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KCE reports vol. 6A Prenatale zorg 177
Study Ref Population Intervention Outcomes Results Comments Study
type
EL
from 1981 to values) weight, gestational age, and mmol/l (postprandial)
1984 in Sweden
skinfold thickness not who were originally
significantly different
randomised to the diet
30 in diet group and 40 in
insulin group showed one or
more episodes of neonatal
morbidity
only group
Avery et al., 4 [507] 33 women at less 30 minutes of exercise 3 to Mean haemoglobin Mean haemoglobin A1c (5.2% 144 women were RCT 1b
1997
than 34 weeks of 4 times weekly (n = 15) vs. A1c
vs. 5.2%, NS)
approached
gestation selected control group (n = 14)
for the study, 43 did not
from a health
Caesarean section Caesarean section: 3 (20%) vs. meet
maintenance
3 (21.4%), p=1.0
inclusion criteria and 68
organisation in the
Neonatal
declined
USA
outcomes Birth weight: 3419 µ 528g vs.
3609 µ 428 g, p=0.30
From the original 33, 1
from
Neonatal hypoglycaemia (NS) the experimental and 3
Gestational age: 39.4 µ 1.2 from
weeks vs.39.7 µ0.9 weeks, p = the control group
0.7
No preterm births
dropped
out
Naylor et
al., 1996
4 [506] 3778 women
presenting for
antenatal care in
Toronto, Canada,
from 1989 to 1992
50-g, 1-hour GCT screening
at 26 weeks of gestation
and diagnostic 100-g, 3hour
OGTT at 28 weeks of
gestation (for all women)
Group 1: known and
treated GDM (n = 143)
Group 2: untreated
Macrosomia
Pre-eclampsia
Caesarean delivery
Macrosomia (> 4000 g):
Group 1 15 (10.5%)
Group 2 33 (28.7%)
Group 3 14 (80%)
Group 4 395 (13.7%)
Macrosomia (> 4500 g):
Group 1 5 (3.5%)
Group 2 7 (6.1%)
Group 3 12 (2.1%)
CH 2b