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KCE reports vol. 6A Prenatale zorg 174
Study Ref Population Intervention Outcomes Results Comments Study
type
Pennsylvania cohort for a composite
Composite perinatal outcome: OR 5.96, 95%CI 1.47- defined as a
Medical Center perinatal outcome
24.16
result
who were variable, and secondary
greater
screened for outcomes: caesarean
Macrosomia greater than 4500g: OR 3.66, 95%CI than or
GDM with the 1- delivery and each
1.30-10.32
equal to
hour GCT at 24- component variable of
135 mg/dl
28 gestational the composite.
Antenatal death: OR 4.61, 95%CI 0.77-27.48 followed by
weeks
a normal 3-
Schoulder dystocia: OR 2.85, 95%CI 1.25-6.51 hours GTT
Endometritis: OR 2.18, 95% CI 1.03-4.63
Cesarean delivery: OR 1.76, 95% CI 0.99-3.14
Retrospecti
ve CH: risk
of selection
bias,
misclassifica
tion bias,
abstractor
bias
Can a prospective application of a risk factor scoring be an alternative screening strategy for diagnosing GDM?
Study Ref Population Intervention Outcomes Results Comments Study
Caliskan et
al., 2004
88 425 Turkish
pregnant women,
recruited in the
antenatal policlinics
of the social Security
Council Maternity
and Women´s
Health Teaching
Hospital
To determine the
effectiveness of a
population-based risk factor
scoring to decrease
unnecessary testing for the
diagnosis of GDM
All patients received a risk
factor scoring over 5
None of the patients with a
score of 0 had GDM
When patients with a score of º
1 were screened with a 50g
GCT (cut-off value of 7.2
mmol/L), the number of women
to be screened decreased by
30% and all cases with GDM
were diagnosed. This strategy
Risk factors were
population-based
The five risk factors were:
- Maternal age º 25
- BMI º 25 kg/m 2
- Diabetes in first degree
relatives
- Prior macrosomic infant
- A history of adverse
EL
EL
type
CH 3