Download het volledig rapport (302 p.) - KCE

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<strong>KCE</strong> reports vol. 6A Prenatale zorg 166 2. m. Herpes simplex What is the incidence of herpes simplex infection in Belgian women? Study Ref Population Interventio Outcomes Results Comments Study EL n type Surveillance network 71 Belgian ? Incidence of herpes simplex infection in women 24 Age of the population SV 4 of 69 sites population between October 2002 and January 2003 between 40 and 70 years Participation to the network is voluntary What is the seroprevalence of herpes simplex type 1 and 2 in a general Belgian population? Study Ref Population Interventio Outcomes Results Comments Study EL n type Pebody et al., 2004 86 The general Belgium Age standardised HSV-1 and HSV-2 HSV-1 CSS 3 populations of and 8 seroprevalences seroprevalence: 67% Belgium and 8 other other European HSV-2 European countries seroprevalence: 11% countries conducted national cross sectional serological surveys for HSV-1 and HSV-2 between 1989 and 2000. Survey sizes ranged
<strong>KCE</strong> reports vol. 6A Prenatale zorg 167 Study Ref Population Interventio n from 3000 to 7166 sera. Outcomes Results Comments Study type Herpes simplex Study Ref Populatio Intervention Outcome Results Comments Study EL n s type RCOG, 25 The risks on transmission and consecutive neonatal herpes are greatest when GL EL 2002 the mother acquires a new infection during late pregnancy. Most of these adopted maternal infections are asymptomatic or unrecognised and it may be difficult from the to distinguish clinically between recurrent and primary HSV infections. guideline and noted Type specific HSV serology has only recently become available and its use and between management has not been fully evaluated. ( ) in the results- Recommended management of women presenting with a first episode of genital herpes during pregnancy: column - Management of the woman should be in line with her clinical condition, which will often involve a five day course of oral acyclovir in standard doses (D-GPP) - Daily suppressive acyclovir in the last suppressive acyclovir in the last four weeks of pregnancy may prevent genital herpes recurrences at term (1b) - Caesarean section is recommended for all women presenting with firstepisode genital herpes lesions at the time of delivery. For women who present with first-episode genital herpes lesions within 6 weeks of the expected date of delivery or onset of preterm labour, elective caesarean may be considered at term, or as indicated, and the paediatricians should be informed. (3) Recommended management of women presenting with a recurrent episode of genital herpes during pregnancy: EL
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NATIONALE RICHTLIJN PRENATALE ZORG:
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KCE reports 1. Effectiviteit en kos
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