Download het volledig rapport (302 p.) - KCE

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<strong>KCE</strong> reports vol. 6A Prenatale zorg 160 What is the impact of primary prevention on the seroconversion rate during pregnancy and what is the impact of secondary prevention on the incidence of congenital toxoplasmosis? Study Ref Population Intervention Outcomes Results Comments Study type EL Foulon 83 11,286 pregnant women in Evaluation of the Impact of primary Reduction of Effect of secondary CH 2b et al., 12 consecutive years in possibilities for preventing prevention on the seroconversion: 63% (p= prevention was studied 1994 Belgium congenital toxoplasmosis seroconversion rate 0.013) in 76 pregnant women during pregnancy at risk of delivering a child with congenital toxoplasmosis Breugel mans et al., 2004 23 First study period (1979- 1982): 2986 Belgian pregnant women Second study period (1983- 1990): 8300 Belgian pregnant women Third period (1991-2001): 16.541 Belgian pregnant women First study period: - Study of the incidence of seroconversion during pregnancy Second study period: - Study of the incidence of seroconversion - Seronegative women received a written list of recommendations on how to avoid a toxoplasma infection during pregnancy Impact of secondary prevention on the incidence of congenital toxoplasmosis Incidence of seroconversion during pregnancy Reduction of the seroconversion in Additional reduction of the incidence of congenital toxoplasmosis: 40% First period: 20/1403 (1.43%) seronegative women seroconverted during pregnancy Second period: 19/3605 (0.53%) seronegative women seroconverted during pregnancy Third period: 8/8492 (0.09%) seronegative women seroconverted Secondary prevention was antibiotic treatment: pyrimathamine 50mg + sulfadiazine 3g daily for 3 weeks alternating with 3 weeks of spiramycin CH 2b
<strong>KCE</strong> reports vol. 6A Prenatale zorg 161 Study Ref Population Intervention Outcomes Results Comments Study type Third study period: the second period during pregnancy - Study of the incidence and the third period of seroconversion compared to the - Seronegative women first period The first prevention received a leaflet: campaign reduced the explaining seroconversion rate by 63% toxoplasmosis as a (p
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KCE reports 1. Effectiviteit en kos
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