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KCE reports vol. 6A Prenatale zorg 116
Study Ref Population Intervention Outcomes Results Comments Study
type
al., 1978 [382] pregnant women from using HBsAg Infants 3 months of age blood of 101/219 (46%) of carrier mothers were
antenatal clinics in West HBsAg positive
269 babies delivered discovered but in the
Midlands, England, from beyond 3 months of
table of ethnic
May 1974 to May 1977 age
17/122 (14%) babies distribution of mothers,
followed up beyond 3 only 100 mothers are
months of age had
persistently high titres of
HBsAg; 64% were Chinese,
30% African-Caribbean and
8% Asian (0 European)
accounted for
What are the consequences for the baby of congenital hepatitis B virus?
Study Ref Population Intervention Outcomes Results Comments Study
Beasley and
Hwang, 1984
4 [384] 22,707 men presenting for
routine examination from
1976 to 1978 in Taiwan
Prospective follow-up
through 1983
HBsAg carrier state
Hepatocellular
carcinoma
Mortality
3,454 HBsAg positive
113/3,454 HCC cases among
HBsAg carriers
3/19,253 cases among noncarriers
103/202 deaths due to
cirrhosis or hepatocellular
carcinoma in HBsAg carrier
group
9/394 deaths due to cirrhosis
or hepatocellular carcinoma in
non-carrier
group
EL
EL
type
CH 2b