Download het volledig rapport (302 p.) - KCE

KCE reports vol. 6A Prenatale zorg 115
Study Ref Population Intervention Outcomes Results
from immigrant
groups 1.04%
Comments Study
type
EL
Brook et
al., 1989
4 [380]
6226 women attending antenatal clinic
at the Royal Free Hospital, London,
from 1983/84 to 1988/89
Screening using HBsAg Number of mothers
HBsAg positive at
first antenatal care
visit
33/6226 (0.5%)
HBsAg positive at
first visit
CS 3
Chrystie 4 [381] Stored serum from antenatal clinics Serology Prevalence among In 1988: 38/3760 (1%)
CSS 3
et al.,
1990 (n = 3760) and 1988 (n = 3975)
women screened women HBsAg
1992
Sera of women originally collected for
positive
rubella in West Lambeth Health
In 1990: 35/3975
authority in London
(0.9%) women HBsAg
positive
Derso et 4 [382] Approximately 240,000 pregnant Serum screening using HBsAg Prevalence of HBsAg 297 pregnant women
CSS 3
al., 1978
women from antenatal clinics in West
carriage in pregnant were HBsAg positive
Midlands, England, from May 1974 to
mothers
May 1977
Overall prevalence of
approx 1/850 (0.1%)
What is the prevalence of congenital hepatitis B virus in the UK?
Study Ref Population Intervention Outcomes Results Comments Study
Ramsay
et al.,
1998
4
[385]
England and Wales from
1985 to 1996
Surveillance of
laboratory reported
cases to PHLS
communicable disease
surveillance centres
Infection in children (under 15
years)
Number of cases due to
mother-to-child transmission
Estimated annual number of
perinatal transmissions which
lead to chronic carriage
Total of 173 cases reported
37/173 (21%) due to
mother-to-child
transmission
93/116 cases of perinatal
transmission leading to
carriage per year
Assumption that 80% of
perinatal infections lead
to chronic carriage
EL
type
CSS 3
Derso et 4 Approximately 240,000 Serum screening Infants HBsAg positive beyond Antigen detected in cord The paper states that 297 COM 3