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<strong>KCE</strong> reports vol. 6A Prenatale zorg 106 Study Ref Population February 1988. Intervention from June 1988 to June 1996 Intervention Outcomes Results Comments Study type What is the effect of intrapartum antimicrobial prophylaxis on the incidence and ecology of the EO neonatal sepsis? Study Ref Population Intervention Outcomes Results Comments Study Moore et al., 2003 73 23 studies, 14 from single hospitals, the rest multi- centre Most studies based in the USA, 1 in Canada, 2 in Australia 2. e. Cytomegalovirus To identify possible effects of intrapartum antimicrobial prophylaxis for prevention of group-B-streptococcal disease on the incidence and ecology of earlyonset neonatal sepsis Trends in the incidence of all-cause, GBS, non-GBS or antibiotic-resistant earlyonset infections during an era when IAP use was increasing Association between IAP exposure and risk of resistant non-GBS colonisation or infection Substantial declines in the incidence of early-onset infections due to GBS and in some settings, other bacteria. Increases in the frequencies of non-GBS or antimicrobialresistant early-onset sepsis have been limited to preterm, lowbirth weight, very-low-birth weight neonates Trend in incidence could be multifactorial Results of analyses of selected populations are not generalisable What is the immunity-status of Belgian pregnant women against cytomegalovirus (CMV) ? Study Ref Population Intervention Outcomes Results Comments Study Donder s et al., 1997 65 1340 eligible women presenting for routine prenatal care at Gasthuisberg University Hospital in Leuven, Belgium during 1993 At the beginning of pregnancy a routine screening was offered in one single bloodtube for the following: - Anti-CMV IgG (1043 women Prevalence of anti- CMV IgG: 16% at age 18 and 50% at age 40 (mean 28.3%) Deficient immunity against rubella: 15/1268 (1.2%) Refusal rate for HIVscreening was 27% EL EL type SR 3 EL type CSS 3
<strong>KCE</strong> reports vol. 6A Prenatale zorg 107 Study Ref Population Intervention were screened) Outcomes Results Comments Study type - Anti-rubella IgG HBsAg carriership (1268 women were screened) 0.23% - HbsAg (1278 No HIV infection women were screened) detected - Anti-HIV IgG Past infection with (1057 women treponema pallidum were screened) occurred in 0.31% - Rapid Plasma (RPR
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KCE reports 1. Effectiviteit en kos
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