Download het volledig rapport (302 p.) - KCE

KCE reports vol. 6A Prenatale zorg 93
Study Ref Population Intervention Outcomes Results Comments Study
type
of metronidazole (48 hours apart) weeks later weeks of gestation after occurring
683 women received placebo (48
treatment
at varying
hours apart)
Similar for women after < 10 times
weeks after treatment
Kekki et al.,
2004
Re-evaluation of gram stain score
on one occasion º 2 weeks later
70 N/A Comparison of no screening with
two screening programs
(clindamycin-metronidazole)
2. c. Chlamydia trachomatis
Cost-effectiveness analysis of
screening and treatment for BV in
early pregnancy among
asymptomatic women at low risk
for preterm delivery
Costeffectiveness
In the placebo group:
significant increase in
spontaneous resolution from
13% at 2 to 39 weeks to
36% at º 10 weeks of
gestation
No significant difference
between screening and noscreening
strategies in the
costs and in the rate of
preterm deliveries
Screening strategy produced
significantly fewer :
Peripartum infections
Postpartum infections
Screening strategy may
become cost-saving if the
rate of preterm deliveries
exceeds 3%
EL
EE 3
What is the prevalence and incidence of chlamydial infection in Belgium?
Study Ref Population Intervention Outcomes Results Comments Study
type
EL
Donders et al., 1997 65 218 women Examination for Prevalence 7/218 (0.4%) Small sample size CSS 3