Download het volledig rapport (302 p.) - KCE

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<strong>KCE</strong> reports vol. 6A Prenatale zorg 72 Study Ref Population Intervention Outcomes Results not accept prenatal diagnosis Comments Study type 5 affected births among 142/623 partners not tested Beta-thalassaemia: 19 of 22 women who returned for follow-up accepted prenatal diagnosis (86%) 4 terminations from 4 affected pregnancies 0 affected births from 3 of 22 women who did not accept prenatal diagnosis 0 affected births among 12/246 partners not tested 1 betathalassaemia birth among 15 EL
<strong>KCE</strong> reports vol. 6A Prenatale zorg 73 Study Ref Population Intervention Outcomes Results unaffected pregnancies Comments Study type Prevalence estimates: 17 infants born each year with beta-thalassaemia (0.03/1000 live births) 160 infants born each year with sickle cell disorder (0.25/1000 live births) Does recording of racial background in the notes of pregnant women help in selective screening for haemoglobinopathies? Study Ref Population Intervention Outcomes Results Comments Study Aspinall et al., 2003 Modell et al., 2000 4 [281] N/A Assessing effectiveness of questions about ethnic origin 4 [276] 400 pregnancies in 138 women in the UK from 1990 to 1994 Audit to evaluate the quality of antenatal screening for haemoglobinopathy and genetic counselling Quality of data collected Haemoglobinopath y affected Screening offered Risk group misclassification as high as 20% June quarter 2000 data from Hospital Episode Statistics indicate ethnic group data missing from 43% of records in London and 37% in England 138/400 (35%) pregnancies with haemoglobinopathy 68/138 (49%) of affected pregnancies had been offered screening at first This study assumes that antenatal screening for Hb disorders is standard practice in the UK EL EL type RW 3 CSS 3
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NATIONALE RICHTLIJN PRENATALE ZORG:
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Nationale richtlijn prenatale zorg:
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KCE reports vol. 6A Prenatale zorg
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KCE reports 1. Effectiviteit en kos
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