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Table l: Drug Therapy of Eypertenslon ln pregnancy<br />

Drug f,kample Q6mmenl<br />

a2-adrenergic<br />

blockers<br />

Beta-blockers Atenolol,<br />

Methyldopa Most commonly used. Safety<br />

Metoprolol<br />

s tYA<br />

well e$tablished Drug of choica<br />

Appear safe. Case repots of<br />

fetal bradycardia, growth<br />

retardataion.<br />

al blockers l:betolol Appea$ effacious. Very<br />

Arteriolar<br />

vaSodilatOrS<br />

scant safety data.<br />

Hydmlazine Effacacious and safe during<br />

pregnatrcy and lactation.<br />

ACE inhibitors Captopril Absolutely contraindicated<br />

Calcium channel<br />

blockers<br />

during preguancy due to<br />

fetal toxicitv.<br />

Diltiazem Appear safe, but not as<br />

much data to support their<br />

US,e.<br />

Diuretics Furosemide Appears safe, but limited<br />

Sodium<br />

nitroprusside<br />

Magnesium<br />

sulfate<br />

efficacy.<br />

Avoid in prespancy due to<br />

potetrtial for fetal<br />

thiocvanate<br />

Treatment of choice for<br />

prevention of ecclamptic<br />

seizures.

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