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Review ofLiterature though the blood pressure remains within the normal range, and the woman has appoximately a 60% chance of developing preeclampsia. If the test is negative, the likelihood of patient developing preeclampsia is about 1 in 100 (Dekker and Sibai, 1991). Isometric exercise test: Isometric hand - grip exercise is known to increase systemic arterial blood pressure, presumably resulting from increased systemic vascular resistance. Degani et al., (1985) subjected one hundered healthy primigravid women to an isometric hand - grip exercise test between 28 and 32 week's gestation. Each woman was placed in the left lateral position, and blood pressure was recorded at regular intervals until it remained stable. The patient then was instructed to press an inflated cuff of a calibrated sphygmomanometer to maximal voluntary contraction for 30 seconds for a three minute period of sustained isometric handgrip exercise. The patient then compressed the inflated sphygmomanometer at a tension level of 50% ofthe subject's previously determined maximal voluntary contraction. Blood pressure measurements were taken on the passive ann, and an increase in the diastolic pressure of 20 mmHg was taken as a positive isometric pressor response. The level of mean arterial blood pressure during the second trimester is a poor predictor of the future development ofeclampsia and might give the clinician a false sense of security when it is negative « 90 mmHg) (Chesley and Sibai, 1987). Blood pressure alone is not always a dependable indicator of severity. For example, an adolescent woman may have 3 + proteinuria and convulsions while her blood pressure is 140/85 mmHg, whereas most women with blood pressure as high as 180/120 mmHg do not have seizures. (Cunningham et al., 1989). 29
- Page 3 and 4: ACKNOWLEDGMENT Above all and first
- Page 5: List of Abbreviations : Apolipoprot
- Page 8 and 9: INTRODUCTION AND AIM OF THE WORK
- Page 10 and 11: Aim of The Work Aim ofthe work Is t
- Page 12 and 13: I . HYPERTENSIVE DISORDERS IN PREGN
- Page 15: -f Etiology of Preeclampsia Review
- Page 18 and 19: Pathogenesis of pre- eclampsia Revi
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- Page 34 and 35: 1. Gestational hypertension (withou
- Page 36: Review ofLiterature However, severe
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- Page 57 and 58: Review ofLiterature appear that mea
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- Page 61 and 62: 4. Hepatic complications: Review of
- Page 63 and 64: Review ofLiterature hemorrhange wit
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- Page 80 and 81: PATIENTS AND METHODS
- Page 85: .. Procedure: Patients and Methods
Review ofLiterature<br />
though the blood pressure remains within the normal range, and the<br />
woman has appoximately a 60% chance of developing preeclampsia. If<br />
the test is negative, the likelihood of patient developing preeclampsia is<br />
about 1 in 100 (Dekker and Sibai, 1991).<br />
Isometric exercise test: Isometric hand - grip exercise is known to<br />
increase systemic arterial blood pressure, presumably resulting from<br />
increased systemic vascular resistance. Degani et al., (1985) subjected<br />
one hundered healthy primigravid women to an isometric hand - grip<br />
exercise test between 28 and 32 week's gestation. Each woman was<br />
placed in the left lateral position, and blood pressure was recorded at<br />
regular intervals until it remained stable. The patient then was instructed<br />
to press an inflated cuff of a calibrated sphygmomanometer to maximal<br />
voluntary contraction for 30 seconds for a three minute period of<br />
sustained isometric handgrip exercise. The patient then compressed the<br />
inflated sphygmomanometer at a tension level of 50% ofthe subject's<br />
previously determined maximal voluntary contraction. Blood pressure<br />
measurements were taken on the passive ann, and an increase in the<br />
diastolic pressure of 20 mmHg was taken as a positive isometric pressor<br />
response.<br />
The level of mean arterial blood pressure during the second<br />
trimester is a poor predictor of the future development ofeclampsia and<br />
might give the clinician a false sense of security when it is negative « 90<br />
mmHg) (Chesley and Sibai, 1987).<br />
Blood pressure alone is not always a dependable indicator of<br />
severity. For example, an adolescent woman may have 3 + proteinuria<br />
and convulsions while her blood pressure is 140/85 mmHg, whereas most<br />
women with blood pressure as high as 180/120 mmHg do not have<br />
seizures. (Cunningham et al., 1989).<br />
29