Analytical and Forensic Toxicology
Analytical and Forensic Toxicology Analytical and Forensic Toxicology
Assay Methods • Spot & spectrochemical • Immunoassays • Non-competitive • Competitive • Enzyme-multiplied immunoassay (EMIT) • Magnetic microparticle chemiluminescent competitive immunosassay • Microparticle capture immunoassay
Assay Methods • Chromatography • Thin layer liquid (TLC) • High performance (pressure) liquid (HPLC) • Gas chromatography (GC) • Mass spectroscopy (MS) • Inductively coupled plasma mass spectroscopy
- Page 1 and 2: Analytical and Forensic Evan S. Sch
- Page 3 and 4: Content • Core Content of Medical
- Page 5 and 6: • Waived • Moderate complexity
- Page 7 and 8: Magic Answer Box? • Old methodolo
- Page 9: Testing “You’re fired, Jack. Th
- Page 13 and 14: • Salicylates • • • Spot Te
- Page 15 and 16: Co-oximetry • Spectrophotometry u
- Page 17 and 18: Spectrochemical • Produce light a
- Page 19 and 20: Immunoassays • Created due to nee
- Page 21: Non-competitive “Sandwich” assa
- Page 29 and 30: Competitive From Goldfranks 9th edi
- Page 31 and 32: Immunoassays • Old - radio immuno
- Page 33 and 34: Magnetic Microparticle Goldfranks 9
- Page 35 and 36: Rf = Rf migration distance of subst
- Page 37 and 38: TLC Goldfranks 9th edition
- Page 39 and 40: TLC Drawbacks • Multiple steps
- Page 41 and 42: Reverse phase chromatography • No
- Page 43 and 44: HPLC
- Page 45 and 46: Gas Chromatography • Expensive
- Page 47 and 48: Mass Spectrometry • Can serve as
- Page 49 and 50: MS Limits • Cannot separate enant
- Page 51 and 52: GC/MS • Expensive equipment • M
- Page 53 and 54: Hair Analysis • Hair grows ~1 cm/
- Page 55 and 56: • Amphetamines • Cannabinoids
- Page 57 and 58: • • • • • Tetrahydrocanna
- Page 59 and 60: • Dronabinol • Efavirenz • NS
Assay Methods<br />
• Chromatography<br />
• Thin layer liquid (TLC)<br />
• High performance (pressure) liquid<br />
(HPLC)<br />
• Gas chromatography (GC)<br />
• Mass spectroscopy (MS)<br />
• Inductively coupled plasma mass<br />
spectroscopy
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