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BOTANY Higher Secondary Second Year - Textbooks Online

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Transgenic microbes<br />

The genetically engineered micro-organisms are being used for the<br />

commercial production of some non-microbial products such as insulin,<br />

interferon, human growth hormone and viral vaccines.<br />

Use of genetically engineered bacterial strain<br />

In 1979, for the first time Anand Mohan Chakrabarty, an Indian born<br />

American scientist developed a strain of Pseudomonas putida that contained<br />

a hybrid plasmid derived by combining parts of CAM and OCT. (CAM<br />

and OCT are the plasmids which contain the genes responsible for the<br />

decomposition of the hydrocarbons like camphor and octane respectively<br />

present in the oil.) This strain could grew rapidly on crude oil because it<br />

was capable of metabolizing hydrocarbons more efficiently. The bacterial<br />

strain called the superbug was produced on a large scale in laboratory,<br />

mixed with straw and dried. When the straw was spread over oil slicks,<br />

the straw soaked up the oil and bacteria broke up the oil into non-polluting<br />

and harmless products. In this way, pollution of land and water due to the<br />

oil slicks can be remedied and the phenomenon is called bioremediation.<br />

It is defined as the use of living microorganisms to degrade environmental<br />

pollutants or prevent pollution. The contaminated sites are restored and<br />

future pollution is prevented.<br />

Benefits from release of genetically modified microorganisms into the<br />

environment.<br />

Protection of environment - Bioremediation of polluted environment.<br />

Microorganisms producing enzymes for food industry.<br />

Microorganisms with improved efficiency of fermentation.<br />

Improved microorganisms for milk industry.<br />

Microorganisms as live attenuated vaccines for health care.<br />

Increasing efficiency of plant nutrition, pest control (safe<br />

biopesticides), protection of plants from climatic stress and protection<br />

of plants from tumour formation and disease.<br />

Self evaluation<br />

I . Choose and write the correct options.<br />

1. One of the following process is employed to introduce a foreign<br />

gene into a cell<br />

a. electrolysis b. electroporation<br />

c. plasmid d. ligation<br />

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