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BOTANY Higher Secondary Second Year - Textbooks Online

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Role of RNA in protein synthesis<br />

There are three types of RNA in the organism namely mRNA, tRNA<br />

and rRNA. mRNA brings the message in the form of codons from DNA to<br />

the site of protein synthesis ie. ribosome. The tRNA molecule performs a<br />

number of functions. The most important one is to carry specific aminoacids<br />

to the site of protein synthesis. The rRNA is found in ribosomes. During<br />

protein synthesis, rRNA provides the site where aminoacids are assembled.<br />

3.9. Genetic code<br />

Aminoacids are the basic units of proteins. Different types of proteins<br />

are synthesized using 20 different aminoacids. But number of aminoacids<br />

and their arrangements vary in different types of proteins. These features<br />

ultimately determined by the nucleotide sequence in the DNA. At the time<br />

of protein synthesis, the sequence of information in the form of three<br />

successive nucleotide bases in the mRNA, which codes for specific<br />

aminoacid in a polypeptide is called genetic code. It is transferred from<br />

DNA to mRNA.<br />

The unit of genetic code is codon, which has three nucleotide bases.<br />

Hence, it is also known as triplet. The four-nucleotide bases adenine,<br />

guanine, cytosine and uracil combine with each other in different<br />

combination to form 64 codons. The mRNA carries number of codons<br />

depending upon the type of protein to be synthesized. For example, if a<br />

protein consists of 100 aminoacids, there will be 300 nucleotide bases in<br />

the genetic code (100 codons).<br />

Characteristics of genetic code<br />

Out of 64 codons, three codons are called stop codons UAA, UAG<br />

and UGA. Remaining 61 codons code 20 different aminoacids. For<br />

example, lysine has two codons AAA and AAG. Proline has four<br />

codons CCA, CCG, CCC and CCU.<br />

In the codons of a particular aminoacid, the first and the second<br />

aminoacids remain the same and the third nucleotide only changes.<br />

The initial or starting codon is AUG, which also code for methionine.<br />

The genetic code is non-overlapping i.e. adjacent codons do not<br />

overlap. The non-overlapping code means that the same letter is not<br />

used to code two different aminoacids. For example, UUU codes for<br />

phenylalanine and CCC for proline.<br />

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