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BOTANY Higher Secondary Second Year - Textbooks Online

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The genome size of an individual is expressed in terms of number of base<br />

pairs either in kilobases (1000 bp) or in megabases (one million bp).<br />

Arabidopsis thaliana is an annual crucifer weed called ‘thale cress’. It has<br />

the smallest nuclear genome of 130 mb with five chromosomes (2n = 10).<br />

The human genome comprises approximately 3.2 x 10 9 nucleotides. The<br />

human mitochondrial genome contains 37 genes and has 16,569 basepairs.<br />

Table showing the genome and approximate number of genes<br />

S. No Name of the organism<br />

Size of the genome<br />

in megabase pairs<br />

In human genome, 38.2% of genome is involved in biochemical<br />

activities like synthesis of immunological and structural proteins, 23.2%<br />

in the maintenance of genome, 21.1% in receiving and giving signals<br />

related to cellular activities and remaining 17.5% in the general functions<br />

of the cell. The functions of 30,000 to 40,000 human genes are known.<br />

Self evaluation<br />

I. Answer the following questions in two or three sentences.<br />

1. Define a gene.<br />

2. Why has ‘one gene one enzyme hypothesis’ been modified into<br />

‘one gene one polypeptide hypothesis’?<br />

3. Define genome.<br />

4. State the percentage of human genome performing various<br />

activities.<br />

II. Answer the following questions in about 100 words.<br />

5. Write short notes on genome.<br />

115<br />

Approximate<br />

number of genes<br />

1. Escherichia coli 4.64 4,400<br />

2. Yeast 12.10 5,800<br />

3. Arabidopsis thaliana 130.00 26,000<br />

4. Drosophila 180.00 13,600<br />

5. Homo sapiens 3,300.00 30,000 - 40,000

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