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The daily requirements of calcium, phosphorus and vitamin D for an adult sheep is about<br />
2.5 g, 1.5 g and 300 to 500 units respectively. The lamb may develop rickets and in adult sheep<br />
it may result in osteomalacia. Supplementing the diet with mineral mixture is essential.<br />
ii) Vitamin A deficiency<br />
Vitamin A deficiency occures in sheep on dry range country side during the periods of<br />
drought. Clinical Vitamin A deficiency does not occur commonly because hepatic storage is<br />
usually good if period of deprivation is not sufficiently long for these stores to reach a critically<br />
low level. Young sheep grazing on drought stricken pasture can suffer deficient diet for 18<br />
months before hepatic stores are depleted and the disease becomes evident. The syndrome<br />
includes night blindness, corneal keratinization,pityriasis, defects in hooves, loss of weight and<br />
infertility. Congential defects are common in the off-spring of deficient dams. For treatment,<br />
place the animals on green pasture and supply vitamin A in feed.<br />
iii) Pregnency Toxaemia of sheep<br />
Amongst domestic farm animals the metabolic disease achieve their greatest importance<br />
in milch and pregnant ewes. Pregnancy taxaeamia of sheep is called as Ketosis of pregnant<br />
ewes and is highly fatal. Hypoglycaemia and Hyperketonae are the primary metabolic<br />
distrubances in ovine ketosis. The most important etiological factor in pregnancy toxaemia is a<br />
decline in the plane of nutrition and short period of stravation (40 hours) during the last two<br />
months of pregnancy particularly large lambs may be affected. It is primarily a disease of<br />
intensive farming system and is relatively rare in extensive grazing units.<br />
The earlier sign is separation from the flocks and apparent blindness, constipation,<br />
grinding of teeth later marked drousiness, tremours of the head, twitching of lips, champing of<br />
jaws and salivations, circulating, sheep goes position of limb and alevation of chin(star<br />
grazing posture), in co-ordination and falling when attempting to walk. A smell of ketones<br />
may be detectable in the breath. In three to four days profound depression comma and death.<br />
For treatment 100 ml of 50% glucose I/V may be given. Supply of molases in ration is also<br />
recommended. During the last two months of pregnany a provision of concentrate at the rate<br />
of 400 g per day; increasing to 800 g per day in last two weeks be made.<br />
6) Posining Caused By<br />
a) The chlorinated Hydrocarbon insecticides<br />
This group includes DDT (Dichloro Diphency Trichloroethane), benezene hexachlordie<br />
(BHC) its pure gramme isomer Lindane, aldrin, dieldrin, chlordane, toxaphane, methocychlor,<br />
DDD, insecticides to control external parasites on sheep or to control insect infestation of<br />
pasture, range forage plants and crop plants. Inhalation, ingestion, aspiration and percutaneous<br />
absorption are possible portals of entry into the body. Most of the insecticides accumulate in<br />
the fat depots, may be excreted in the milk in dangerous amounts. Fat depots are a potential<br />
source of danger in that sudden mobilazation of the blood stream and the appearance of signs of<br />
toxicity. The toxic effects produced includes increased excitability and irritability followed by<br />
muscle tremor, weakness and paralysis and teeth grinding is noticed. Complete anorexia<br />
occurs constantly.<br />
Treatment: Short acting barbiturate (Pantobarbitone), later followed by a dose of chloral<br />
hydros by mouth. When the insecticide has been applied on the skin washing with detergent is<br />
advisable. It is usually recommemded that calcium borogluconate should be given I/V possibly<br />
together with glucose saline.<br />
b) Organo-Phosphorus insecticides<br />
The group includes some of the most dangerous chemicals which are highly toxic but they<br />
are used and recommended for control of insects attacking plants, available for control of<br />
internal parasites of sheep. Some of the compounds are chloration, carbophenothion, Demton,<br />
Dasnon, Dimethylaparation, Trichlorphon, Dioxalthion, Malathion, Darathion, Scharadan etc.<br />
For blow flies, keds, lice and ticks diazon, cobal malathion are used. The recommended<br />
concentrations of dips sprays are 0.04% diaznon, 0.25% for coral, 0.5% for malathion. As<br />
anthelmintics Rueleam (Asuntol), Coral (Bayer 21/199) and Neguvon (Bayer L13/59), have<br />
been used. The clinical signs of poisoning are profuse salivation, muscle stiffness dyspnoea,<br />
with open mouth breathing diarrhea and muscular tremors. Such cases can be treated by given.<br />
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