Accoun ts Letters - Thieme Chemistry

Letters
X Table of Contents
1310
Improved Method for the Preparation of
Macrocyclic Diamides
D. T. Gryko, D. Gryko, J. Jurczak
1313
Stereoselective Conjugate Addition of Alkyl Groups
to (S)-4-(tert-Butyldimethylsilyloxy)-2-phenylsulfonyl-2-cyclopentenone
by Means of Trialkylaluminum
Reagents
T. Yakura, K. Tanaka, M. Iwamoto, M. Nameki, M. Ikeda
1316
A New Route to L-Iduronate Building-blocks for the
Synthesis of Heparin-like Oligosaccharides
R. Ojeda, J. L. de Paz, M. Martín-Lomas, J. M. Lassaletta
1319
Novel Axial Chiral Sulfur-oxazoline Ligands with a
Biphenyl Backbone
Y. Imai, W. Zhang, T. Kida, Y. Nakatsuji, I. Ikeda
1322
A Concise Route to Carbasugars
Y. Le Merrer, C. Gravier-Pelletier, W. Maton, M. Numa,
J.-C. Depezay
1325
Synthetic Studies towards Mniopetals (I). A Short
Synthesis of a Key Intermediate for the Total
Synthesis of Mniopetals
J. Jauch
O
O
S
H2N OMe
+
OMe
TBDMSO
HO
O
O
H 2N
O
O
O
O
O
MeOH, NaOMe
48 h
O
NH
O
S
HN
O
57%
O
O
O
NH
O
HN
O
+ S
S
O
NH
O
HN
O
O
O
TBDMSO R
10%
SO2Ph R3Al SO2Ph toluene
OBn
O
MeO2C O
5 Steps, 17% overall
R
N M
SR' M RS'
N
R M
O
O
(S,aS )
3
M=PdCl2
RS'
O O
H H
M
(S,aR)
not found
Up to 82% ee was attained in palladium-catalyzed allylic
alkylation.
N
O
R
OTDS
PO OP
PO
PO
O
*
OP
+
*
O
S S
Si
SiO
*
S
*
S
OH SiO
+
*
S
*
S
OP
OH
Si = TBDMS