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michigan hypertension core curriculum - State of Michigan

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side effects particularly well. A holistic and integrated approach to HTN management in this population<br />

is necessary for the best outcomes and should include coordination <strong>of</strong> management by what are <strong>of</strong>ten<br />

multiple care providers.<br />

A non-medical, but real concern is the cost <strong>of</strong> medication. 10, 11 Elderly individuals are less likely<br />

to be working and more likely to be on fixed incomes than their younger counterparts. In addition,<br />

as elderly patients may have co-morbid medical conditions, their out <strong>of</strong> pocket medical costs may<br />

be substantial prior to starting anti-hypertensive therapy. The financial issue also impacts access to<br />

health care and BP monitoring which must be considered. In assessing elderly individuals, a provider<br />

needs to be comfortable with having frank and open discussions about the financial realities <strong>of</strong> care<br />

and design a treatment plan that minimizes the economic burden to the treated individual. Such an<br />

approach must involve aggressive and deliberate use <strong>of</strong> generic medications, minimize polypharmacy<br />

and encourage consistent feedback from the treated individual to ensure that the HTN treatment is not<br />

placing an undue burden on the individual.<br />

Hypertension treatment is covered in a separate section <strong>of</strong> the book, but there are a few issues<br />

worth noting. The first is that several studies have demonstrated the effectiveness and utility <strong>of</strong> treating<br />

HTN in older and elderly individuals. 12-14 Cardiovascular events, most notable stroke and heart failure,<br />

can be reduced and treated individuals experience reduced morbidity and in many cases, reduced<br />

mortality. Secondly, the treatment goals for older and elderly individuals are no different from those in<br />

the general population. Specifically, using the JNC-7 recommendations as a guide, BP should be less<br />

than 140 mmHg over less than 90 mmHg in most individuals and less than 130 mmHg over less than<br />

80 mmHg in individuals with DM or CKD. Third, an appreciation for cultural differences is necessary to<br />

achieve optimal results. 15 In regards to specific medications, the thiazide diuretics have shown great<br />

efficacy in the elderly population, as have ACE-I and calcium channel blockers. 13,16,17 Nevertheless,<br />

thiazide diuretics and calcium channel blockers will lower BP more as monotherapy than other<br />

antihypertensive drug classes; however, single drug therapy with any drug class is unlikely to control<br />

BP, especially SBP to below goal levels in most elderly antihypertensives. Thus, in most situations the<br />

practitioner will be using combination drug therapy, typically a diuretic or calcium channel blocker, in<br />

combination with a RAAS inhibitor in a slow, deliberate approach to BP lowering in the elder population.<br />

52 Hypertension Core Curriculum

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