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Study of respiratory symptoms among sputum positive

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An induration <strong>of</strong> 2 1Omm is classified as <strong>positive</strong> in all persons who<br />

do not meet any <strong>of</strong> the above criteria but who belong to one is more <strong>of</strong> the<br />

following groups having high risk for TB. Injected-dmg users know to be<br />

HIV seronegative persons who have other medical conditions that have<br />

been reported to increase the risk for progressing from latent TB infection<br />

to active TB, including diabetes mellitus, conditions requiring prolonged<br />

high-dose corticosteroid therapy and other immunosuppressive therapy<br />

(including bone marrow and organ transplantation), chronic renal failure,<br />

some hematologic disorders (e.g. leukemias and lymphomas). Other<br />

specific malignancy (e.g. carcinoma <strong>of</strong> the head or neck). Weight loss <strong>of</strong><br />

210 % below ideal body weight, silicosis, gastrectomy and jegunoileal<br />

bypass. Residents and employees <strong>of</strong> high risk. Children < 4 years <strong>of</strong> age or<br />

infants, children and adolescents exposed to adults in high-risk categories.<br />

Congegate setting: prisons, jails, nursing homes and other long-<br />

tern1 facilities for the elderly, l~ealth care facilities (including some<br />

residential mental health facilities), and homeless shelters.<br />

An induration <strong>of</strong> > 15mm is classified as <strong>positive</strong> in persons who do<br />

not meet any <strong>of</strong> the above criteria (Bloch, 1998).<br />

b- Medical research council test:<br />

A new diagnostic test for TB has been described that can be done as<br />

two skin tests, or from blood samples based on the reaction to 38.A and<br />

38.G peptide <strong>of</strong> 38 kDa. Reaction to peptide 38.A identifies people who<br />

have had BCG vaccination or previous TB, or those who have active TB.<br />

Reaction to 38.G identifies people the first two <strong>of</strong> these categories but not<br />

the third, as people with active TB lose the T-cell response to it. Thus, the

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