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Study of respiratory symptoms among sputum positive

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¥rruew <strong>of</strong>Literature<br />

Predisposing Factors for TB (Seaton, 1989) :<br />

1) Nutrition: Malnutrition is believed to predispose to tuberculosis.<br />

2) Housing: Poor housing conditions with overcrowding such as still exist<br />

in many common lodging houses may contribute to the disease (Patel,<br />

1985 and Capewell, 1986).<br />

3) Occupation : Tuberculosis is commoner <strong>among</strong> the health service<br />

pr<strong>of</strong>essions due to an increased risk <strong>of</strong> exposure to the disease<br />

(Festenstein 1984 and Geiseler et al., 1987). Workers in occupations<br />

giving rise to pulmonary silicosis such as masons, quarry workers,<br />

knife, grinders and coalminers have a greater risk <strong>of</strong> developing<br />

tuberculosis (Snider, 1978 ).<br />

4) Alcoholism: Tuberculosis is common in alcoholics, contributory factors<br />

probably being malnutrition, adverse social factors and a direct effect <strong>of</strong><br />

alcohol on host defenses (Smith and Palmer, 1976).<br />

5) Cigarette smoking : Cigarette smoking is a principal cause <strong>of</strong><br />

preventable diseases and premature death world- wide. It is implicated<br />

in a large number <strong>of</strong> diseases in the different body systems. Smoking is<br />

considered as the chief contributor to chronic pulmonary disease in<br />

adults (Alcalde et al., 1996 ).<br />

The studies that were carried out to explore the role <strong>of</strong> smoking in<br />

developing active IB revealed controversial results, probably because <strong>of</strong><br />

the interference <strong>of</strong> other factors, such as age, alcohol consumption or<br />

socioeconomic status. However, a significant <strong>positive</strong> correlation was<br />

found between the degree <strong>of</strong>smoking and the release <strong>of</strong>intracellular and<br />

extra cellular reactive oxidants in peripheral blood (Richards et al., 1989).<br />

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