Final Program - American Society of Gene & Cell Therapy

Final Program 

AMERICAN SOCIET Y OF GENE & CELL THERAPY 

14 th Annual Meeting 

SEAT TLE, WA | MAY 18-21, 2 011 

Jointly sponsored by Indiana University 

School of Medicine and the 

American Society of Gene & Cell Therapy

ASGCT Officers and 

Board of Directors 

President (10/11) 

Barrie J. Carter, PhD 

President-Elect (10/11) 

R. Jude Samulski, PhD 

Vice President (10/11) 

Xandra O. Breakefield, PhD 

Secretary (13) 

John J. Rossi, PhD 

Treasurer (11) 

Beverly L. Davidson, PhD 

Board Members 

Christopher Baum, MD 

Fabio Candotti, MD 

Roberto Cattaneo, PhD 

Cynthia Dunbar, MD 

Helen E. Heslop, MD 

Brendan Lee, MD, PhD 

Stephen J. Russell, MD, PhD 

Brian P. Sorrentino, MD 

Samuel C. Wadsworth, PhD 

Mark A. Kay, MD, PhD 

Chair, Advisory Council 

(ex-officio) 

Malcolm K. Brenner, MD, PhD 

Editor-in-Chief, Molecular Therapy 

(ex-officio) 

ASGCT 

Executive Office 

555 East Wells Street, Suite 1100 

Milwaukee, WI 53202 

Phone: 414.278.1341 | Fax: 414.276.3349 

info@asgct.org | www.asgct.org 

Mary Dean – Executive Director 

Erin Hankey – Administrative Coordinator 

Ken Janowski – Program Manager 

Roseann Marotz – Meetings Manager 

David Wood – Senior Meetings and Membership Manager 

Tara Withington, CAE – Consulting Partner 

Contents 

A Welcome from Barrie J. Carter, PhD . . . . . . . . . . . . . . . . . . . .2 

Annual Meeting Supporters . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3 

Annual Meeting Exhibitors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4 

Committee Meeting Schedule . . . . . . . . . . . . . . . . . . . . . . . . . .5 

Committee Rosters. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6 

Abstract Planning Committee 

& Group Coordinating Reviewers . . . . . . . . . . . . . . . . . . . . . . 11 

Excellence in Research Award 

& Travel Grant Recipients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 

Outstanding New Investigator 

& Outstanding Achievement Awards Recipients . . . . . . . 14 

Faculty Listing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 

General Meeting Information . . . . . . . . . . . . . . . . . . . . . . . . . 19 

Washington State Convention Center Floor Plans. . . . . . 24 

Schedule-at-a-Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 

Detailed Program Schedule . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Exhibit Hall Floor Plan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 

Exhibitor Descriptions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78 

Exhibitor Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 

Seattle Fun Facts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Housing Information and Map of Seattle . . . . . . . . . . . . . . 86 

Abstract Directory. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Abstract Author Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150 

14TH ANNUAL MEETING | SEATTLE, WA | MAY 18-21, 2011 1

2 

A Welcome from Barrie J. Carter, PhD 

Dear Colleagues, 

On behalf of the American Society of Gene & Cell Therapy, welcome to the Society’s 

14 th Annual Meeting in ASGCT’s founding city, Seattle, Washington, USA. As I look 

back to the last time ASGCT was in Seattle, I’m impressed with how far our field has 

advanced since 2007. We have seen significant progress in gene and cell therapy for 

immune deficiency diseases, including most recently Wiskott Aldrich Syndrome as 

well as for retinal degeneration, Parkinson’s disease, and a variety of other inherited 

and acquired diseases. We have also seen the first cell therapy product approved for 

cancer and other remarkable progress in cellular therapies, particularly those based 

on modified T cells. In addition, oncolytic viruses are progressing rapidly to advanced 

clinical trials. As a result of this broad ranging progress, we are beginning to see 

investments by large Pharma and Biotech in the arena. 

The Annual Meeting program features many of the developments in the field over the 

past year in 27 scientific symposia, 10 education sessions, 28 oral abstract sessions, 3 

poster sessions, and 5 meet-the-investigator lunch sessions. 

I am honored to have Dr. Victor Dzau present the keynote lecture during the George 

Stamatoyannopoulos Lecture and Dr. George Daley to present on combining gene 

and cell therapy using iPS cells during the Presidential Symposium. In addition, Dr. 

Malcolm Brenner, the 2011 Outstanding Achievement Award winner, will give a 

retrospective of his contributions to the field. 

I emphatically thank the many groups who have come together to support the 

Annual Meeting: the generosity of the exhibitors, non-profit organizations and 

industry supporters contributes greatly to the overall success of ASGCT’s conference. 

Please be sure to take time to visit the vendors in the exhibit hall this year. 

Thank you also to the Annual Meeting faculty for sharing their expertise and time to 

make this a truly unique event. 

And finally, thank you, the Annual Meeting participants, for attending the Society’s 

Annual Meeting. Welcome to my hometown! 

Sincerely, 


President, ASGCT 

FINAL PROGRAM American Society of Gene & Cell Therapy

Annual Meeting Supporters (as of April 2011) 

Our grateful acknowledgement to the following for their educational grant in support of this program: 

Partner Level Support 

Registration Bags 

Contributor Level Support 

Notebook and Exhibit Hall Guide Coffee Mugs Printing of the Final Program 

Patron Level Support 

Conference Grant Support Outstanding New Investigator Awards (2) Travel Grants (5) 

Excellence in Research Award (1) 

Excellence in Research Award (1) Travel Grant (1) General Meeting Support 

Travel Grants (2) Outstanding New Investigator Award (1) General Meeting Support Travel Grants (3) 


and Travel Grants (3) 

Conference Grant Support 

Excellence in Research Awards (2) 

Travel Grants (4) 

Travel Grant (1) 

Job Bank Booklet 

Supported in part by March of Dimes 

Foundation Grant No. 4-FY11-533. 



Marketing Support 


4 

Annual Meeting Exhibitors 

The American Society of Gene & Cell Therapy would like to acknowledge the 

following exhibitors that are exhibiting at the ASGCT 14th Annual Meeting. 

Adaptive TCR Technologies 

Aldevron 

AltheaDx 

American Society of Gene & Cell Therapy 

Axis-Shield PoC 

BioSpherix 

Caliper Life Sciences 

Center for Cellular and Molecular 

Therapeutics at the Children’s Hospital of 

Philadelphia 

Data Unlimited International, Inc. 

Freezerworks – A Division of Dataworks 

Development, Inc. 

GENE TOOLS, LLC 

GENEWIZ, Inc. 

Horizon Discovery Ltd 

Lonza 

Lovelace Respiratory Research Institute 

Mary Ann Liebert, Inc. 

Meridian Life Science, Inc. 

MolMed S.p.A. 

NanoSight 

National Gene Vector Biorepository 

(NGVB) 

Nature Publishing Group 

Nature Technology Corporation 

Nexcelom Bioscience 

NHLBI Gene Therapy Resource Program 

NIH Office of Biotechnology Activities 

Omnia Biologics, Inc. 

Penn Vector Core, University of 

Pennsylvania 

Polyplus-transfection 

Production Assistance for Cellular 

Therapies (PACT) 

ReGenX Biosciences 

Social & Scientific Systems, Inc. 

St. Jude Children’s Research Hospital 

Techulon, Inc. 

TriLink BioTechnologies, Inc. 

Waisman Biomanufacturing 

Make time each day to peruse the products, services and publications offered by the 

exhibiting companies. Network and meet new colleagues in a relaxed atmosphere. 

Stop by the Job Exchange Area. 

Thank you 14 th Annual Meeting Exhibitors! 


Committee Meeting Schedule 

Committee terms technically commence and conclude at the Annual Meeting. Incoming chair and committee member terms 

officially go into effect on May 21, 2011 at the Business Meeting. All meetings will be held at the Washington State Convention 

Center unless otherwise noted. 

WEDNESDAY, MAY 18 th 

12:00 pm – 1:15 pm Translational Science & Product Development 

Committee Meeting 

THURSDAY, MAY 19 th 

WSCC Room 211 

Publications Committee Meeting WSCC Room 212 

1:00 pm – 2:30 pm Ethics Committee Meeting WSCC Room 211 

Education Committee Meeting WSCC Room 212 

7:00 pm – 8:30 pm Molecular Therapy Editorial Board Meeting Sheraton Seattle, Cirrus Room 

FRIDAY, MAY 20 th 

12:00 pm – 1:15 pm Bio-Industry Liaison Committee Meeting WSCC Room 211 

SATURDAY, MAY 21 st 

International Committee Meeting WSCC Room 212 

Advisory Council Meeting WSCC Room 213 

7:30 am – 8:00 am Society Annual Business Meeting WSCC 618-620 

12:15 pm – 1:45 pm Membership Committee Meeting WSCC Room 212 

SOCIETY ANNUAL BUSINESS MEETING 

Scientific Committee Meetings 

Cancer Gene & Cell Therapy; Cardiovascular Gene & Cell Therapy; 

Chemical Gene & Cell Therapy; Gene & Cell Therapy of Genetic 

Diseases; Genetic Vaccines; Physical Gene & Cell Therapy & 

Vectorology; Respiratory Tract Gene & Cell Therapy; Stem Cell; Viral 

Gene Transfer Vectors 

WSCC 6E 

The ASGCT Business Meeting will be conducted on Saturday, May 21, 7:30 am – 8:00 am. A continental breakfast will be served at 

7:15 am in the Room 618-620. 

All ASGCT members are welcome to attend. Election results will be announced, new officers will be installed and the Society’s 

finances and membership statistics will be reviewed. We welcome your input and participation! 


6 

Committee Rosters 

Advisory Council 

Chair 

Mark A. Kay, MD, PhD (2010 - 2011) 

Katherine P. Ponder, MD (2011 - 2012) 

Members 

David M. Bodine, PhD (2009 - 2014) 

Barrie J. Carter, PhD (2011 - 2016) 

Kenneth Cornetta, MD (2010 - 2015) 

Theodore Friedmann, MD (2007 - 2012) 

Leaf Huang, PhD (2006 - 2011) 

Carl H. June, MD (2010 - 2015) 

Andra E. Miller, PhD (2007 - 2012) 

Luigi M. Naldini, MD, PhD (2008 - 2013) 

Arthur W. Nienhuis, MD (2008 - 2013) 

Katherine P. Ponder, MD (2009 - 2014) 

Bio-Industry Liaison Committee 

Chair 

Seng H. Cheng, PhD (2010 - 2012) 

Members 

Estuardo Aguilar-Cordova, PhD (2008 - 2014) 

Dale Ando, MD (2010 - 2013) 

Joseph T. Bruder, PhD (2010 - 2013) 

Anthony T. Cheung, PhD (2008 - 2014) 

Michael Fons, PhD (2007 - 2013) 

Joyce L. Frey-Vasconcells, PhD (2009 - 2012) 

William F. Kaemmerer, PhD (2010 - 2013) 

Karen Kozarsky, PhD (2007 - 2013) 

Brett P. Monia, PhD (2010 - 2013) 

Jeffrey M. Ostrove, PhD (2008 - 2011) 

Gabor M. Rubanyi, MD, PhD (2010 - 2013) 

Vladimir Slepushkin, MD, PhD (2006 - 2012) 

Sean M. Sullivan, PhD (2010 - 2013) 

Geoff P. Symonds, PhD (2006 - 2012) 

Thomas Tillett (2010 - 2013) 

Cancer Gene & Cell Therapy Committee 

Chair 

Margaret Black, PhD (2011 - 2012) 

Laurence JN Cooper, MD, PhD (2009 - 2011) 

Members 

Karen S. Aboody, MD (2011 - 2014) 

Chiara Bonini, MD (2009 - 2012) 

Renier J. Brentjens, MD, PhD (2010 - 2013) 


Evanthia Galanis, MD, DSc (2011 - 2014) 

Stephen Gottschalk, MD (2007 - 2013) 

Paola Grandi, PhD (2011 - 2014) 

Maciej S. Lesniak, MD, MHCM, FACS (2009 - 2012) 

Richard A. Morgan, PhD (2009 - 2012) 

John J. Nemunaitis, MD (2008 - 2014) 

Daniel H. Sterman, MD (2007 - 2013) 

Bakhos A. Tannous, PhD (2011 - 2014) 

Savio L.C. Woo, PhD (2010 - 2013) 

Lily Wu, MD, PhD (2010 - 2013) 

Cardiovascular Gene & Cell Therapy 

Committee 

Chair 

Barry J. Byrne, MD, PhD (2010 - 2012) 

Members 

David A. Dichek, MD (2010 - 2013) 

Michael P. Murphy, MD (2009 - 2012) 

Timothy O’Brien, MD, PhD (2009 - 2012) 

Michael J. Passineau, PhD (2010 - 2013) 

Gabor M. Rubanyi, MD, PhD (2010 - 2013) 

Matthew L. Springer, PhD (2007 - 2013) 

Karen A. Vincent, PhD (2008 - 2014) 

Krisztina M. Zsebo, PhD (2011 - 2014) 

Chemical Gene & Cell Therapy Committee 

Chair 

Ian MacLachlan, PhD (2011 - 2012) 

Theresa M. Reineke, PhD (2010 - 2011) 

Members 

Roger C. Adami, Ph.D. (2007 - 2013) 

Todd Giorgio, PhD (2010 - 2011) 

Stephen L. Hart, PhD (2011 - 2014) 

James G. Hecker, MD, PhD (2006 - 2012) 


Suzie H. Pun, PhD (2007 - 2013) 


Kevin G. Rice, PhD (2010 - 2013) 

Cyrus R. Safinya, PhD (2010 - 2013) 

Millicent O. Sullivan, PhD (2010 - 2013) 

David B. Weiner, PhD (2010 - 2013) 



Clinical Trials and Regulatory Affairs 

Committee 

Chair 

Carl H. June, MD (2009 - 2011) 

Members 

Dale Ando, MD (2010 - 2013) 

Jacqueline Corrigan-Curay, MD, JD (2008 - 2014) 

Carl H. June, MD (2011 - 2012) 

Elizabeth Kang, MD (2009 - 2012) 

Thomas M. Miller, PhD (2008 - 2011) 

Glenn F. Pierce, MD, PhD (2011 - 2014) 

Daniel M. Takefman, PhD (2009 - 2012) 

Peter K. Working, PhD, DABT (2010 - 2013) 

J. Fraser Wright, PhD (2009 - 2012) 

Education Committee 

Co-Chairs 

Linda B. Couto, PhD (2010 - 2012) 

Fulvio Mavilio, PhD (2009 - 2011) 

Sonia I. Skarlatos, PhD (2011 - 2012) 

Members 

William F. Goins, PhD (2007 - 2013) 

Scott Q. Harper, PhD (2010 - 2013) 

Tal Kafri, MD, PhD (2007 - 2013) 

Harry L. Malech, MD (2010 - 2013) 

Matthew H. Porteus, MD, PhD (2010 - 2013) 

Suzie H. Pun, PhD (2009 - 2012) 

Luk H. Vandenberghe, PhD (2010 - 2013) 

Ethics Committee 

Chair 

Nelson Wivel, MD (2010 - 2012) 

Members 

Roger H. Bertolotti, PhD (2009 - 2012) 

R. Michael Blaese, MD (2010 - 2013) 

Theodore Friedmann, MD (2008 - 2014) 

Edward I. Ginns, MD, PhD (2009 - 2012) 

Dieter C. Gruenert, PhD (2010 - 2013) 


Financial Affairs Committee 

Chair 


Members 

Xandra O. Breakefield, PhD (2010 - 2012) 

Beverly L. Davidson, PhD (2009 - 2011) 

John J. Rossi, PhD (2010 - 2013) 

R. Jude Samulski, PhD (2009 - 2011) 

Gene & Cell Therapy of Genetic and 

Metabolic Diseases Committee 

Chair 

Valder Arruda, MD, PhD (2010 - 2012) 

Members 

Alessandra Biffi, MD (2011 - 2014) 

Fatima Bosch, PhD (2010 - 2013) 

Fabio Candotti, MD (2010 - 2011) 

Lawrence C. Chan, MD (2010 - 2013) 

Stephanie Cherqui, PhD (2011 - 2014) 

Andrew M. Davidoff, MD (2010 - 2013) 

Nuria Morral, PhD (2009 - 2012) 

Sihong Song, PhD (2011 - 2014) 

Thierry C. VandenDriessche, PhD (2009 - 2012) 

Charles P. Venditti, MD, PhD (2008 - 2014) 

Robin Ziegler, MS (2010 - 2013) 

Genetic Vaccines Committee 

Chair 

Helen E. Heslop, MD (2009 - 2011) 

Jeffrey J. Molldrem, MD (2011 - 2012) 

Members 

Ronald Alvarez, MD (2006 - 2012) 

Austin J. Barrett, MD (2010 - 2013) 

Si-Yi Chen, MD, PhD (2010 - 2013) 


Sattva S. Neelapu, MD (2010 - 2013) 

Hematologic and Immunologic Gene and 

Cell Therapy Committee 

Chair 

Michel Sadelain, MD, PhD (2010 - 2012) 

Members 

Alessandro Aiuti, MD, PhD (2008 - 2014) 

Gianpietro Dotti, MD (2010 - 2013) 

David W. Emery, PhD (2006 - 2012) 

Karin M.L. Gaensler, MD (2006 - 2012) 

John T. Gray, PhD (2011 - 2014) 

Manuel Grez, PhD (2009 - 2012) 


Paris Margaritis, D.Phil (2011 - 2014) 

Derek A. Persons, MD, PhD (2007 - 2013) 

Karen E. Pollok, PhD (2006 - 2012) 

Barbara Savoldo, MD, PhD (2010 - 2013) 


8 


Immune Responses to Gene & Cell Therapy 

Committee 

Chair 

Pedro Lowenstein, MD, PhD (2011 - 2012) 

Adrian J. Thrasher, MD, PhD (2009 - 2011) 

Members 

Andrea Amalfitano, DO, PhD (2010 - 2013) 

Catherine M. Bollard, MBChB, FRACP, FRCPA (2011 - 2014) 

Andrew Byrnes, PhD (2010 - 2013) 

Roland W. Herzog, PhD (2010 - 2013) 

Shulin Li, PhD (2011 - 2014) 

Gerald S. Lipshutz, MD (2010 - 2013) 

John D. Mountz, MD, PhD (2007 - 2013) 

Denise Sabatino, PhD (2008 - 2014) 

Yiping Yang, MD, PhD (2010 - 2013) 

Infectious Diseases and Vaccines Committee 

Chair 

Roberto Cattaneo, PhD (2009 - 2011) 

Margaret A. Liu, MD (2011 - 2012) 

Members 


Philip R. Johnson, MD (2010 - 2013) 

Wayne A. Marasco, MD, PhD (2006 - 2012) 

Eric Poeschla, MD (2010 - 2013) 

Steven Polyak, MD (2010 - 2013) 

Bruce E. Torbett, PhD, MSPH (2009 - 2012) 

James M. Wilson, MD, PhD (2007 - 2013) 

Stefan Worgall, MD, PhD (2006 - 2012) 

International Committee 

Chair 

John Rasko, MBBS, PhD (2009 - 2011) 


Members 

Alberto Auricchio, MD (2010 - 2013) 

Christopher Baum, MD (2010 - 2013) 

Guangping Gao, PhD (2009 - 2012) 

Bobby Gaspar, MD, PhD (2008 - 2014) 

Salima Hacein-Bey Abina, PhD (2008 - 2014) 

Amit Nathwani, MD, PhD (2011 - 2014) 


Takashi Shimada, MD, PhD (2009 - 2012) 

Sander van Deventer, MD, PhD (2007 - 2013) 


Seppo Ylä-Herttuala, MD, PhD, FESC (2005 - 2011) 

Membership Committee 

Chair 

Guangping Gao, PhD (2011 - 2012) 

Dexi Liu, PhD (2010 - 2011) 

Members 

Donna Armentano, PhD (2011 - 2014) 

Alberto Auricchio, MD (2011 - 2014) 


Michele P. Calos, PhD (2010 - 2013) 

Dexi Liu, PhD (2006 - 2012) 

Toya Ohashi, MD (2008 - 2014) 

Keiya Ozawa, MD, PhD (2011 - 2014) 

Maria-Grazia Roncarolo, MD, PhD (2005 - 2011) 

John J. Rossi, PhD (2005 - 2011) 

Junzhi Wang, PhD (2011 - 2014) 

Savio L.C. Woo, PhD (2010 - 2011) 

Ex-Officio 

Robert M. Frederickson, PhD (2005 - 2012) 

Musculo-Skeletal Gene & Cell Therapy 

Committee 

Chair 

Jerry R. Mendell, MD (2010 - 2012) 

Members 

Jeffrey Chamberlain, PhD (2010 - 2013) 

Alan R. Davis, PhD (2007 - 2013) 

Richard J. Gregory, PhD (2010 - 2013) 

Dwight Koeberl, MD, PhD (2010 - 2013) 

Alan J. Nixon, DVM, MS (2007 - 2013) 

Shin’ichi Takeda, MD, PhD (2010 - 2013) 

Kathryn Wagner, MD, PhD (2011 - 2014) 

Bing Wang, MD, PhD (2010 - 2013) 

Neurologic & Ophthalmic Gene & Cell 

Therapy Committee 

Chair 

Maria G. Castro, PhD (2009 - 2011) 

Mark H. Tusznski (2011 - 2012) 

Members 

Robin R. Ali, PhD (2010 - 2013) 

Alessandra Biffi, MD (2011 - 2014) 

William J. Bowers, PhD (2009 - 2012) 

Xandra O. Breakefield, PhD (2009 - 2012) 


Thomas W. Chalberg, PhD (2011 - 2014) 

Beverly L. Davidson, PhD (2008 - 2011) 

Florian Eichler, MD (2011 - 2014) 

David J. Fink, MD (2010 - 2013) 

William Hauswirth, PhD (2010 - 2013) 

Anne Messer, PhD (2010 - 2013) 

Seshidhar Reddy Police, DVM, MS, PhD (2011 - 2014) 

Deborah J. Watson, PhD (2009 - 2012) 

John H. Wolfe, VMD, PhD (2010 - 2013) 



Nominating Committee 

Chair 

David M. Bodine, PhD (2010 - 2012) 

Members 

Christopher Baum, MD (2010 - 2011) 


Roland W. Herzog, PhD (2010 - 2011) 

Maria-Grazia Roncarolo, MD, PhD (2010 - 2011) 

Oligonucleotide and RNAi Therapeutics 

Committee 

Chair 

Kevin V. Morris, PhD (2011 - 2012) 

Bruce Sullenger, PhD (2009 - 2011) 

Members 

C. Frank Bennett, PhD (2010 - 2013) 

Brian D. Brown, PhD (2010 - 2013) 

Dirk Grimm, PhD (2010 - 2013) 

Ryszard Kole, PhD (2011 - 2014) 

Matthew Levy, PhD (2011 - 2014) 

Paul B. McCray, Jr., MD (2008 - 2014) 



Marco Weinberg, PhD (2010 - 2013) 

Physical Gene & Cell Therapy and 

Vectorology Committee 

Chair 

Richard Heller, PhD (2011 - 2012) 

Shulin Li, PhD (2009 - 2011) 

Members 


Michael Fons, PhD (2009 - 2011) 


Amir S. Khan, PhD (2011 - 2012) 

Shulin Li, PhD (2011 - 2012) 

R. Scott McIvor, PhD (2009 - 2012) 

Carol H. Miao, PhD (2009 - 2012) 

Lluis M. Mir, PhD, DSc (2009 - 2012) 

Matthew H. Porteus, MD, PhD (2010 - 2012) 

Sean M. Sullivan, PhD (2010 - 2013) 

Program Committee 

Co-Chairs 




Gay Crooks, MD (2011 - 2012) 

Ronald G. Crystal, MD (2010 - 2012) 

John F. Engelhardt, PhD (2010 - 2011) 

R. Jude Samulski, PhD (2011 - 2012) 

Members 

Valder Arruda, MD, PhD (2010 - 2012) 


Bruce A. Bunnell, PhD (2009 - 2011) 

Barry J. Byrne, MD, PhD (2010 - 2012) 



Seng H. Cheng, PhD (2010 - 2012) 


Linda B. Couto, PhD (2010 - 2012) 

Larry A. Couture, PhD (2010 - 2012) 

Gay Crooks, MD (2009 - 2011) 

Terence R. Flotte, MD (2011 - 2012) 



Carl H. June, MD (2009 - 2011) 

Jane S. Lebkowski, PhD (2011 - 2012) 

Shulin Li, PhD (2009 - 2011) 

Margaret A. Liu, MD (2011 - 2012) 

Pedro Lowenstein, MD, PhD (2011 - 2012) 

Fulvio Mavilio, PhD (2009 - 2011) 

Jerry R. Mendell, MD (2010 - 2012) 







Daniel R. Salomon, MD (2010 - 2011) 

Sonia I. Skarlatos, PhD (2011 - 2012) 


Adrian J. Thrasher, MD, PhD (2009 - 2011) 




10 


Publications Committee 

Chair 

Donald B. Kohn, MD (2009 - 2011) 

Francis C. Szoka, Jr., PhD (2011 - 2012) 

Members 

Hans-Peter Kiem, MD, FACP (2007 - 2013) 

Donald B. Kohn, MD (2011 - 2012) 

Arthur W. Nienhuis, MD (2010 - 2013) 


Rachel Salzman, DVM (2008 - 2014) 

Francis C. Szoka, Jr., PhD (2008 - 2011) 

Respiratory Tract Gene & Cell Therapy 

Committee 

Chair 



Members 


David A. Dean, PhD (2010 - 2013) 

John F. Engelhardt, PhD (2010 - 2013) 


Deborah Gill, PhD (2008 - 2014) 

Uta Griesenbach, PhD (2010 - 2013) 

Jay K. Kolls, MD (2007 - 2013) 

David W. Parsons, PhD (2007 - 2013) 

Susan D. Reynolds, PhD (2011 - 2014) 

Stem Cell Committee 

Chair 

Gay Crooks, MD (2009 - 2011) 


Members 

Karen S. Aboody, MD (2009 - 2012) 

Fernando D. Camargo, PhD (2009 - 2012) 

Gay Crooks, MD (2011 - 2012) 

James Ellis, PhD (2009 - 2012) 


Kazuo Ohashi, MD, PhD (2006 - 2012) 

Evan Y. Snyder, MD, PhD, FAAP (2009 - 2012) 

Alice F. Tarantal, PhD (2009 - 2012) 

Tissue Engineering Committee 

Chair 

Daniel R. Salomon, MD (2010 - 2011) 

Members 

Dan Gazit, DMD, PhD (2010 - 2013) 

William V. Giannobile, DDS, DMedSc (2010 - 2013) 

Bruce L. Levine, PhD (2010 - 2013) 

Paul Y. Liu, MD, FACS (2010 - 2013) 

Tatiana Segura, PhD (2010 - 2013) 

Stephanie Simek, PhD (2010 - 2013) 

Translational Science and Product 

Development Committee 

Chair 

Larry A. Couture, PhD (2010 - 2012) 

Members 

Joy Cavagnaro, PhD, DABT, RAC, FATS (2010 - 2013) 


Boro Dropulic, PhD (2011 - 2014) 

Derek J. Hei, PhD (2010 - 2013) 

Douglas J. Jolly, PhD (2010 - 2013) 


Alain Rolland, PharmD, PhD (2010 - 2013) 

Richard O. Snyder, PhD (2010 - 2013) 

Viral Gene Transfer Vectors Committee 

Chair 


Members 

Mavis Agbandje-McKenna, PhD (2010 - 2013) 

Ian E. Alexander, MBBS (2011 - 2014) 

John A. Chiorini, PhD (2010 - 2013) 

John T. Gray, PhD (2007 - 2013) 

Brendan Lee, MD, PhD (2008 - 2011) 


Philip Ng, PhD (2009 - 2012) 

Samuel D. Rabkin, PhD (2009 - 2012) 

Stephen J. Russell, MD, PhD (2010 - 2013) 

Dmitry M. Shayakhmetov, PhD (2009 - 2012) 

Jackie Sheng, PhD (2011 - 2014) 

David Strayer, MD, PhD (2009 - 2012) 


Abstract Planning Committee 

Each year this committee, which is made up of the ASGCT President, President-Elect, Secretary, Program Committee Co-Chairs 

and two invited members, reviews abstracts that are suggested by the various categories for the Presidential Symposium and the 

Clinical Oral Abstract Session. 


Carter BioConsulting 

Seattle, WA 

Ronald G. Crystal, MD 

Weill Medical College of 

Cornell University 

New York, NY 

Abstract Reviewers 

Committee Chair 


RNA Virus Vectors 

Coordinating Reviewer 

Grant D. Trobridge, PhD 

Reviewers 

Brian D. Brown, PhD 

Boris Fehse, PhD 

Karen E. Pollok, PhD 

Jiing-Kuan Yee, PhD 

AAV Vectors 


Saswati Chatterjee, PhD 

Reviewers 

Douglas M. McCarty, PhD 

Selvarangan Ponnazhagan, PhD 

Kirsten AK Weigel-Van Aken, MD 

Weidong Xiao, PhD 

Adenovirus and Other DNA 

Virus Vectors 


Joseph C. Glorioso, III, PhD 

Reviewers 

Terence R. Flotte, MD 

Steven C. Ghivizzani, PhD 

Matthew D. Weitzman, PhD 

James M. Wilson, MD, PhD 

John F. Engelhardt, PhD 

University of Iowa College of Medicine 

Iowa City, IA 

Donald B. Kohn, MD 

University of California, Los Angeles 

Los Angeles, CA 


Beckman Research Institute City of Hope 

Duarte, CA 

DNA Vectorology 

& Gene Targeting 


Perry B. Hackett, PhD 

Reviewers 

Carlos F. Barbas, III, PhD 

Paula M. Cannon, PhD 

Zoltan Ivics, PhD 

Matthew H. Wilson, MD, PhD 

Physical Methods 

of Delivery 


Daniel G. Anderson, PhD 

Reviewers 

Guangping Gao, PhD 

Jordan J. Green, PhD 

Matthew H. Porteus, MD, PhD 

Mark Tracy, PhD 

Chemical and 

Molecular Conjugates 


Sean M. Sullivan, PhD 

Reviewers 

Arash Hatefi, PhD, PharmD 

Young Jik Kwon, PhD 

Suzie H. Pun, PhD 

Kevin G. Rice, PhD 


University of North Carolina at Chapel Hill 

Chapel Hill, NC 


Vical, Inc. 

San Diego, CA 

Genetic and Metabolic 

Diseases Gene & Cell Therapy 


Valder Arruda, MD, PhD 

Reviewers 

Christopher Doering, MD 

Daniel G. Miller, MD, PhD 

Nuria Morral, PhD 

Katherine P. Ponder, MD 

Cardiovascular 

Gene & Cell Therapy 


K. K. Wong, MD 

Reviewers 

Barry J. Byrne, MD, PhD 

Dongsheng Duan, PhD 

Roger J. Hajjar, MD 

Prediman K. Shah, MD 

Neurologic & Ophthalmic 



Alessandra Biffi, MD 

Reviewers 

Robin R. Ali, PhD 

Alberto Auricchio, MD 

Krystof Bankiewicz, MD, PhD 

Nathalie Cartier-Lacave, MD 


12 

Abstract Reviewers 

Musculo-skeletal 



Jacques P. Tremblay, PhD 

Reviewers 

Jeffrey Chamberlain, PhD 

Paula Clemens, MD 

Johnny Huard, PhD 

Xiao Xiao, PhD 

Infectious Diseases 

and Vaccines 


Bruce L. Levine, PhD 

Reviewers 

Don J. Diamond, PhD 

Stephen M. Kaminsky, PhD 

Patric J. S. Lundberg, PhD 

J. Fraser Wright, PhD 

Cancer - Immunotherapy 


Michael Jensen, MD 

Reviewers 

Laurence J.N. Cooper, MD, PhD 

Lawrence S. Lamb, Jr., PhD 

Daniel Powell, PhD 

Barbara Savoldo, MD, PhD 

Cancer – Oncolytic Viruses 


Patrick B. Arbuthnot, MD, PhD 

Reviewers 

E. Antonio Chiocca, MD, PhD 

Evanthia Galanis, MD, DSc 

David H. Kirn, MD 

Takafumi Nakamura, PhD 

Cancer - Targeted 



Stephen J. Forman, MD 

Reviewers 

Joseph S. Anderson, PhD 

Catherine M. Bollard, MBChB, FRACP, FRCPA 

David L. Porter, MD 

Michel Sadelain, MD, PhD 

Hematologic and Immunologic 



Donald B. Kohn, MD 

Reviewers 


Salima Hacein-Bey Abina, PhD 

Eirini P. Papapetrou, MD, PhD 

Derek A. Persons, MD, PhD 

Lung and Respiratory 

Disease Gene & Cell Therapy 


Bruce A. Bunnell, PhD 

Reviewers 

David A. Dean, PhD 

Uta Griesenbach, PhD 

Larry G. Johnson, MD 

Deborah E. Sullivan, PhD 

Immunologic 

& Host Responses in 



Si-Yi Chen, MD, PhD 

Reviewers 

Michael A. Barry, PhD 

Nicholas Restifo, MD 

Xiao-Tong Song, PhD 

FINAL PROGRAM American Society of Gene & Cell Therapy 

Gene Regulation 


Philip D. Gregory, PhD 

Reviewers 

Donna Armentano, PhD 

Michele P. Calos, PhD 

John Forsayeth, PhD 

Bruce E. Torbett, PhD, MSPH 

Oligonucleotide 

& RNAi Therapeutics 



Reviewers 

C. Frank Bennett, PhD 

Joel R. Chamberlain, PhD 

Dirk Grimm, PhD 

Kevin V. Morris, PhD 

Stem Cell Therapies 


John A. Zaia, MD 

Reviewers 

Walter J. Koch, PhD 

Ann M. Leen, PhD 

Punam Malik, MD 

Dorothee von Laer, MD 

Cell Processing and Vector 

Production 


Larry A. Couture, PhD 

Reviewers 

Lorraine A. Matheson, MS 

Isabelle Rivière, PhD 

William P. Swaney, MS 

Johannes C.M. van der Loo, PhD 

Special thanks to the abstract reviewers for their time and expertise.

Excellence in Research Award 

& Travel Grant Recipients 

Excellence in Research Awards – For Students and Postdoctoral Fellows 

Christie Bell 

University of Pennsylvania 

Adeno-Associated Virus Serotype 9 Uses Galactose as a Cellular 

Receptor To Transduce Conducting Airway 

Miguel Mano 

ICGEB - International Centre for Genetic Engineering and 

Biotechnology 

High-Throughput Genome-Wide siRNA Screening Unravels Cellular 

Factors Critical for AAV Transduction 

Stefania Merella 

San Raffaele Telethon Institute for Gene Therapy 

Assessing the Impact of Lentiviral Vector Integration on Splicing of 

Cellular Genes at the Genome-Wide Level 

Travel Awards – For Students and Postdoctoral Fellows 

Jennifer E. Adair 

Sonny O. Ang 

Cynthia C. Bartholomae 

Etiena Basner-Tschakarjan 

Troy Brady 

Michael J. Castle 

Marcela P. Cataldi 

Daniela Cesana 

Diptiman Chanda 

Szu-Ting Chou 

Darin J. Falk 

Anthony S. Fargnoli 

Richard Gabriel 

Bernhard R. Gentner 

Zakaria Grada 

Katrin Hacke 

Nilesh P. Ingle 

Mahesh Jonnalagadda 

Sunitha Kakarla 

The Excellence in Research Awards and Travel Grants 

were made possible through grant support from: 


Lotta M. Kangasniemi 

Hirotaka Kawano 

Matthias W. Kron 

Marven Lamarre 

Chin-Yu Lin 

Bridget Lins 

Leszek Lisowski 

Angelo L. Lombardo 

Jiamiao Lu 

Anna Manfredi 

Maria D I Manunta 

Citra N. Mattar 

Harald G. Messer 

Annarita Miccio 

Joel Montane 

Claudio Mussolino 

Shruthi Naik 

Md Nasimuzzaman 

Anna Paruzynski 

Christina Rauschhuber 

Max von Pettenkofer-Institute 

Micro RNA Knockdown Significantly Enhances Adenovirus 

Replication and Vector Production 

Samantha Scaramuzza 

San Raffaele Telethon Institute for Gene therapy 

Gene Therapy with Lentiviral Vector Transduced CD34+ Cells for the 

Treatment of Wiskott-Aldrich Syndrome 

Paul N. Valdmanis 

Stanford University 

Role of Ago2 and microRNAs in Mammalian Development 

Nicole K. Paulk 

Karin Pike-Overzet 

Valentina Poletti 

Nagesh Pulicherla 

Marco Ranzani 

Diana Rommelfanger 

Shoshannah L. Roth 

Ivette M. Sandoval 

Erica B. Schleifman 

Shen Shen 

Laura J. Smith 

Masataka Suzuki 

Hiroki Torikai 

Yu-Shan Tseng 

Lindsay M. Wallace 

Hongjie Wang 

Jiehua Zhou 

Qinghui Zhou 

Excellence in Research Award (1) Excellence in Research Award (1) Travel Grant (1) Excellence in Research Award (1) Travel Grants (2) 

Travel Grants (3) Excellence in Research Award (1) 

and Travel Grants (3) 

Excellence in Research Awards (2) 

Travel Grant (1) 




14 

Outstanding New Investigator 

& Outstanding Achievement Awards Recipients 

Outstanding New Investigator Award Winners 

The following Outstanding New Investigator Award winners were selected by the Advisory Council based on merit and their 

contributions to the field of gene and cell therapy. The recipients will present their work at the special Outstanding New 

Investigator Symposium on Saturday, May 21st at 8:00 am. 

Hiroyuki Nakai, MD, PhD 

University of Pittsburgh 

School of Medicine 

Pittsburgh, Pennsylvania 

In Vivo Viral Genome and Capsid Biology 

of Recombinant AAV Vectors 

The Outstanding New Investigator Awards were made possible through grant support from: 

Outstanding Achievement Award Winner 

The Outstanding Achievement Award winner was selected by the ASGCT Advisory Council as an example of an ASGCT member 

who has achieved a pioneering research success through a lifetime of significant scientific contributions to the field of gene and 

cell therapy. The Outstanding Achievement Award winner will present the talk Cell and Gene Therapy - Putting it Together during a 

special Outstanding Achievement Award plenary lecture on Friday, May 20th at 3:45 pm. 


Baylor College of Medicine 

Houston, Texas 

Miguel Sena-Esteves, PhD 

University of Massachusetts 

Medical School 

Worcester, Massachusetts 

AAV-Mediated Gene Therapy for Neuro- 

Metabolic Diseases and Brain Tumors 


Qizhen Shi, MD, PhD 

Medical College of Wisconsin 

Milwaukee, Wisconsin 

Targeting Factor VIII (FVIII) Expression 

to Platelets for Gene Therapy of 

Hemophilia A with Inhibitors

Faculty Listing 

Annemieke Aartsma-Rus, 

PhD 

Leiden University Medical 

Center 

Leiden, Netherlands 

Karen S. Aboody, MD 

City of Hope National Medical 

Center 

Duarte, CA 

Roger C. Adami, PhD 

Marina Biotech 

Bothell, WA 

Laura K. Aguilar, MD, PhD 

Advantagene, Inc. 

Waban, MA 

Estuardo Aguilar-Cordova, 

PhD 

Advantagene, Inc. 

Waban, MA 


University College London 

London, United Kingdom 

Andrea Amalfitano, DO, PhD 

Michigan State University 

East Lansing, MI 

Brian H. Annex, MD 

University of Virginia School of 

Medicine 

Charlottesville, VA 


Genzyme Corporation 

Framingham, MA 




Philadelphia, PA 


Telethon Institute of Genetics 

& Medicine 

Rome, Italy 

Krystof Bankiewicz, MD, 

PhD 

University of California San 

Francisco 

San Francisco, CA 

Glen Barber, PhD 

University of Miami School of 

Medicine 

Miami, FL 

Richard C. Becker, MD 

Duke Heart Center 

Durham, NC 


Isis Pharmaceuticals, Inc. 

Carlsbad, CA 


San Raffaele Telethon Institute 

for Gene Therapy (HSR-TIGET) 

Milano, Italy 

Adam Bogdanove, PhD 

Iowa State University 

Ames, IA 

Fatima Bosch, PhD 

Universitat Autonoma de 

Barcelona 

Bellaterra, Spain 

Marnix Bosch, PhD, MBA 

Northwest Biotherapeutics 

Bethesda, MD 

Nicholas Boulis, MD 

Emory University School of 

Medicine 

Atlanta, GA 

Malcolm K. Brenner, MD, 

PhD 


Houston, TX 

Renier J. Brentjens, MD, PhD 

Memorial Sloan Kettering 

Cancer Center 

New York, NY 


Mt. Sinai School of Medicine 

New York, NY 

Christine Brown, PhD 

City of Hope National Medical 

Center 

Duarte, CA 

Wilson W. Bryan, MD 

Food and Drug Administration 

Rockville, MD 


University of Florida College of 

Medicine 

Gainesville, FL 


Stanford University School of 

Medicine 

Stanford, CA 


NIH/NHGRI 

Bethesda, MD 


University of Southern 

California 



Carter BioConsulting 

Seattle, WA 


INSERM 

Paris, France 

Maria G. Castro, PhD 

Cedars-Sinai Medical Center, 

UCLA 


Toni Cathomen, PhD 

Hannover Medical School 

Hannover, Germany 


Mayo Clinic 

Rochester, MN 

Marina Cavazzana-Calvo, 

MD, PhD 

Hopital Necker 

Enfants-Malades 

Paris, France 


University of Washington 


Seattle, WA 

Seng H. Cheng, PhD 



Kim N. Chi, MD 

BC Cancer Agency Research 

Vancouver, Canada 

Karen L. Christman, PhD 

University of California, 

San Diego 

La Jolla, CA 

Laurence JN Cooper, MD, 

PhD 

University of Texas M.D. 

Anderson Cancer Center 

Houston, TX 

Lawrence Corey, MD 

Fred Hutchinson Cancer 

Research Center 

Seattle, WA 


Beckman Research Institute of 

City of Hope 

Duarte, CA 




New York, NY 

George Q. Daley, MD, PhD 

Children’s Hospital Boston 

Boston, MA 

Kevin D’Amour, PhD 

ViaCyte, Inc. 

San Diego, CA 

Andrew M. Davidoff, MD 

St. Jude Children’s Research 

Hospital 

Memphis, TN 


University of Iowa Carver 

College of Medicine 

Iowa City, IA 


University of Rochester 

Rochester, NY 

David L. DiGiusto, PhD 


Duarte, CA 

Christopher Doering, PhD 

Emory University 

Atlanta, GA 


University of Missouri School 

of Medicine 

Columbia, MO 

Victor J. Dzau, MD 

Duke University 

Durham, NC 


16 

Faculty List 

James Ellis, PhD 

Hospital for Sick Children 

Toronto, Canada 

Michael Emerman, PhD 



Seattle, WA 

David W. Emery, PhD 


Seattle, WA 


University of Iowa Carver 

College of Medicine 

Iowa City, IA 

Eva L. Feldman, MD, PhD 

University of Michigan 

Ann Arbor, MI 

Mitchell H. Finer, PhD 

bluebird bio 

Cambridge, MA 

Kevin M. Flanigan, MD 

Nationwide Children’s 

Research Institute 

Columbus, OH 




Worcester, MA 

Toshiyoshi Fujiwara, MD, 

PhD 

Okayama University Graduate 

School 

Okayama, Japan 

Karin M.L. Gaensler, MD 

University of California San 

Francisco 



Mayo Clinic 

Rochester, MN 

Doina Ganea, PhD 

Temple University School of 

Medicine 





Worcester, MA 

Richard S. Geary, PhD 

Isis Pharmaceuticals, Inc. 

Carlsbad, CA 

Julie Gehl, MD, PhD 

Copenhagen University 

Hospital Herlev 

Herlev, Denmark 

Steven Craig Ghivizzani, 

PhD 

University of Florida 




Pittsburgh, PA 

William F. Goins, PhD 

University of Pittsburgh School 



Stephen Gottschalk, MD 


Houston, TX 

John T. Gray, PhD 

St. Jude Childrens Research 

Hospital 

Memphis, TN 

Paul A. Grayburn, MD, FACC 

Cardiology Consultants of 

Texas 

Dallas, TX 

Henry T. Greely, JD 

Stanford University Law School 

Palo Alto, CA 

Philip Greenberg, MD 


Seattle, WA 


Imperial College Faculty of 

Medicine 



University of Heidelberg 

Heidelberg, Germany 

Robert E. Guldberg, PhD 

Georgia Tech 

Atlanta, GA 

Geoffrey Gurtner, MD 

Stanford Hospital & Clinics 

Stanford, CA 

Hideyoshi Harashima, PhD 

Hokkaido University 

Sapporo, Japan 

Mirjam H.M. Heemskerk, 

PhD 

Leiden University Medical 

Center 

Leiden, Netherlands 

Akseli Hemminki, MD, PhD 

University of Helsinki 

Helsinki, Finland 

Serge Herson, MD 

Hopital Pitie-Salpetriere 

Paris, France 

Roland W. Herzog, PhD 



Michael C. Holmes, PhD 

Sangamo BioSciences, Inc 

Richmond, CA 

Wenlin Huang, PhD 

Sun Yat-Sen University Cancer 

Center 

Guangzhou, Peoples Republic 

of China 





Seattle Children’s Research 

Institute 

Seattle, WA 


University of Arkansas for 

Medical Sciences 

Little Rock, AR 

Philip R. Johnson, MD 

The Children’s Hospital of 

Philadelphia 


Douglas J. Jolly, PhD 

Tocagen, Inc. 

San Diego, CA 

Eric Juengst, PhD 

University of North Carolina at 

Chapel Hill 



Carl H. June, MD 



William F. Kaemmerer, PhD 

Medtronic, Inc. 

Minneapolis, MN 

Tal Kafri, MD, PhD 


Chapel Hill 


Alexander Kalinkovich, PhD 

Weizmann Institute of Science 

Rehovot, Israel 


Weill Cornell Medical College 

New York, NY 

Elizabeth Kang, MD 

NIH/NIAID 

Bethesda, MD 

Michael Kaplitt, MD, PhD 



New York, NY 

Howard L. Kaufman, MD 

Rush University Cancer Center 

at Rush University Medical 

Center 

Chicago, IL 



Medicine 

Stanford, CA 

Hans-Peter Kiem, MD 



Seattle, WA 

Nancy M.P. King, JD 

Wake Forest University School 


Winston-Salem, NC 


JENNEREX Biotherapeutics, 

Incorporated 


Dwight Koeberl, MD, PhD 

Duke University Medical 

Center 

Durham, NC

Faculty List 

Ryszard Kole, PhD 

AVI BioPharma 

Bothell, WA 


UC Irvine 

Irvine, CA 


University of Alabama at 

Birmingham 

Birmingham, AL 

Jane S. Lebkowski, PhD 

Geron Corp 

Menlo Park, CA 

Ann Leen, PhD 


- CAGT 

Houston, TX 

Arthur Levin, PhD 

Santaris Pharma A/s 

San Diego, CA 

Shulin Li, PhD 

MD Anderson Cancer Center 

Houston, TX 

Brian Lichty, PhD 

McMaster University 

Hamilton, Canada 

Andre Lieber, MD, PhD 


Seattle, WA 

Jay R. Lieberman, MD 

University of Connecticut 

Health Center 

Farmington, CT 

Dexi Liu, PhD 



Paul Y. Liu, MD, FACS 

Roger Williams Medical Center 

Providence, RI 

Christian L. Lorson, PhD 

University of Missouri 

Columbia, MO 

Pedro Lowenstein, MD, PhD 

Cedars Sinai Medical Center, 

UCLA 


Paolo Macchiarini, MD, PhD 

Karolinska Institutet 

Stockholm, Sweden 

Harry L. Malech, MD 

NIH/NIAID Laboratory of Host 

Defenses 

Bethesda, MD 


Cincinnati Children’s Hospital 

Cincinnati, OH 

Lorraine Matheson 

Indiana University 

Indianapolis, IN 

Sebastien Maury, MD, PhD 

Assistance Publique - 

Hopitaux De Paris 

Paris, France 

Anton P. McCaffrey, PhD 

Trilink Biotechnologies 

San Diego, CA 


The Research Institute at 

Nationwide Children’s Hospital 

Columbus, OH 

Grant McFadden, PhD 



Jerry R. Mendell, MD 

The Research Institute at 

Nationwide Children’s Hospital 

Columbus, OH 

Carol H. Miao, PhD 


Seattle, WA 



Seattle, WA 

Thomas Miller, PhD 

National Institutes of Health 

Bethesda, MD 

Jeffrey J. Molldrem, MD 

M.D. Anderson Cancer Center 

Houston, TX 

Richard A. Morgan, PhD 

National Cancer Institute 

Columbia, MD 


Indiana University School of 

Medicine 


Lindsey A. Muir 


Seattle, WA 

Charles E. Murry, MD, PhD 


Seattle, WA 


University of Pittsburgh School 



Luigi M. Naldini, MD, PhD 

University Vita-Salute San 

Raffaele 

Milano, Italy 

John J. Nemunaitis, MD 

Mary Crowley Cancer Research 

Centers 

Dallas, TX 

Philip Ng, PhD 


Houston, TX 

John M. Pagel, MD, PhD 



Seattle, WA 

Eirini P. Papapetrou, MD, 

PhD 

Memorial Sloan-Kettering 

Cancer Center 

New York, NY 

Duanqing Pei, PhD 

Guangzhou Institute of 

Biomedicine and Health, CAS 

Guangzhou, Peoples Republic 

of China 

Louis M. Pelus, PhD 

Indiana University 


Marc Penn, MD, PhD 

Cleveland Clinic Foundation 

Cleveland, OH 


St. Jude Children’s Research 

Hospital 

Memphis, TN 

Thomas Petersen, PhD 

Kirkland, WA 

Steven Piantadosi, MD, PhD 

Cedars-Sinai Medical Center 


Michel Pohl, PhD 

INSERM 

Paris, France 


Washington University School 


St. Louis, MO 

Selvarangan Ponnazhagan, 

PhD 

University of Alabama at 

Birmingham 

Birmingham, AL 

Matthew H. Porteus, MD, 

PhD 


Medicine 

Stanford, CA 

Daniel J. Powell, Jr., PhD 





Seattle, WA 

David J. Rawlings, MD 

University of Washington; 

Dept of Pediatrics 

Seattle, WA 

Thomas A. Reh, PhD 



Seattle, WA 

Susan D. Reynolds, PhD 

National Jewish Health 

Denver, CO 

Stanley Riddell, MD 



Seattle, WA 



Cancer Center 

New York, NY 


18 

Faculty List 

Paul D. Robbins, PhD 



Richard Roden, PhD 

The Sidney Kimmel 

Comprehensive Cancer 

Center at Johns Hopkins 

Baltimore, MD 

Alain Rolland, PharmD, PhD 

Vical 

San Diego, CA 

Botond Roska, PhD 

Friedrich Miescher Institute 

Basel, Switzerland 


Beckman Research Institute 


Duarte, CA 

Gabor M. Rubanyi, MD, PhD 

Cardium Therapeutics, Inc. 

San Diego, CA 

David W. Russell, MD, PhD 


Seattle, WA 


Mayo Clinic 

Rochester, MN 



Cancer Center 

New York, NY 

Daniel R. Salomon, MD 

The Scripps Research Institute 

La Jolla, CA 



Chapel Hill 


Brenda M. Sandmaier, MD 



Seattle, WA 

Tatiana Segura, PhD 

University of California, Los 

Angeles 





Worcester, MA 

Lonnie D. Shea, PhD 

Northwestern University 

Evanston, IL 


Medical College of Wisconsin 

Milwaukee, WI 

Arun Srivastava, PhD 

University of Florida College of 

Medicine 


Patrick S. Stayton, PhD 


Seattle, WA 

Duncan J. Stewart, MD, 

FRCPC 

Ottawa Hospital Research 

Institute 

Ottawa, Canada 

Rainer F. Storb, MD 



Seattle, WA 


Vical, Inc. 

San Diego, CA 

Daniel M. Takefman, PhD 

Food and Drug Administration 

Rockville, MD 

James D. Thompson, PhD 

Quark Pharmaceuticals Inc. 

Boulder, CO 

Adrian J. Thrasher, MD, PhD 

Institute of Child Health 


John F. Tisdale, MD 

NIH 

Bethesda, MD 


The Scripps Research Institute 

La Jolla, CA 

Greg Towers, PhD 

University College London 



Université Laval and CRCHUQ 

Sainte-Foy, Canada 


Washington State University 

Pullman, WA 

Luk H. Vandenberghe, PhD 



Thierry C. VandenDriessche, 

PhD 

University of Brussels 

Leuven, Belgium 

Gabriele Varani, PhD 


Seattle, WA 

Richard G. Vile, PhD 

Mayo Clinic 

Rochester, MN 

Christof von Kalle, MD, PhD 

NCT Heidelberg 

Heidelberg, Germany 




Christopher M. Walker, PhD 

The Research Institute 

Columbus, OH 

Kirsten AK Weigel-Van 

Aken, MD 

University of Florida - Cancer 

& Genetics Research Complex 



The Salk Institute 

San Diego, CA 

Dominic J. Wells, PhD 

Royal Veterinary College 


David A. Williams, MD 

Children’s Hospital Boston 

Boston, MA 

Andrew A. Wilson, MD 

Boston University School of 

Medicine 

Boston, MA 








Houston, TX 

Steven P. Wilson, PhD 

University of South Carolina 


Columbia, SC 

Nelson Wivel, MD 



Darren Wolfe, PhD 

Diamyd Inc. 



Children’s Hospital of 

Philadelphia - Pathology and 

Laboratory Medicine 



Temple University 




Chapel Hill 


Masato Yamamoto, MD, PhD 

University of Minnesota 

Minneapolis, MN 

Masayuki Yamato, PhD 

Tokyo Women’s Medical 

University 

Shinjuku-ku, Japan 

Seppo Ylä-Herttuala, MD, 

PhD, FESC 

University of Kuopio 

Kuopio, Finland 

Joseph Zabner, MD 

University of Iowa 

Iowa City, IA 


Beckman Research Institute of 


Duarte, CA

General Meeting Information 

American Society Of Gene & Cell Therapy 

Mission and Vision 

The American Society of Gene & Cell Therapy’s (ASGCT) mission 

is to advance knowledge, awareness, and education leading 

to the discovery and clinical application of genetic and cellular 

therapies to alleviate human disease. 

ASGCT’s vision is to be a catalyst for bringing together scientists, 

physicians, patient advocates, and other stakeholders to 

transform the practice of medicine by incorporating the use of 

genetic and cellular therapies to control and cure human disease. 

Abstract Volume - Molecular Therapy 

All abstracts, except Late Abstract Submissions, accepted for 

presentation at the ASGCT 14 th Annual Meeting have been 

published in the May supplement of Molecular Therapy. Each 

attendee will receive one copy of the supplement along 

with their registration materials. Late Abstract Submissions 

accepted for presentation have been printed in a booklet 

that will be distributed to each attendee. In addition, the 

Late Abstract Submissions will be published in the July 2011 

issue of Molecular Therapy. The option for itinerary download 

for Personal Digital Assistants (PDAs) is also available. Please 

contact ASGCT for a link at (414) 278-1341 or info@asgct.org. 

Admission 

Official name badges will be required for admission to all 

ASGCT sessions. All Annual Meeting attendees receive a name 

badge with their registration bag. Name badges should be 

worn at all times inside the convention center, as badges will be 

used to control access to sessions and activities. Attendees are 

cautioned against wearing their name badges while away from 

the convention center as badges may draw unwanted attention 

to your status as visitors to Seattle, Washington. 

Boxed Lunches 

Pre-ordered boxed lunches will be available for pick-up at the 

registration desk according to the schedule below: 

Wednesday, May 18 12:00 pm – 12:30 pm 

Thursday, May 19 1:00 pm – 1:30 pm 

Friday, May 20 12:00 pm – 12:30 pm 

Saturday, May 21 12:15 pm – 12:45 pm 

All boxed lunches must have been pre-ordered via the Annual 

Meeing registration form before May 9 and pick-up of boxed 

lunches is by ticket only. 

Business Center (FedEx Office) 

There is a FedEx Office located in the Washington State 

Convention Center in the Upper Pike Street Lobby. It is open 

Monday – Friday from 7:00 am to 9:00 pm and Saturday and 

Sunday from 9:00 am to 6:00 pm. Phone: (206) 467-1767. 

Business Meeting 

Join the Society’s leadership for a business meeting and 

continental breakfast. 

Saturday, May 21, 2011 

7:30 am – 8:00 am (Light continental breakfast at 7:15 am) 

Room 618-620, Level Six 

All members are welcome. See page 5 for more details. 

Camera/Recording Policy 

It is the policy of ASGCT that no cameras are permitted in 

the meeting sessions, exhibit hall, or poster sessions, with the 

exception of a professional photographer hired by ASGCT to 

capture images for use in Society archival and promotional 

materials. Please refrain from taking any photos in those 

locations. Audio and/or videotaping is strictly prohibited. 

Your attendance at ASGCT events implies your permission for 

images captured during these events to be used for the purposes 

of ASGCT archival and promotional materials and waives your 

rights for compensation or ownership of these images. 

Cell Phones & PDAs 

As a courtesy to all presenters and attendees, please ensure that 

cell phone and PDA ringers are turned off or silenced during all 

sessions as they may interfere with session audio. 

Committee Meetings 

Most standing and scientific committees will meet during 

the Annual Meeting. See page 5 for Committee Meeting 

information. 

Concierge Desk 

Seattle offers a wide variety of activities and restaurants to meet 

all tastes and budgets. A Concierge Desk is located in the Upper 

Pike Street Lobby of the Washington State Convention Center, 

staffed by the Seattle Convention and Visitors Bureau, who can 

help you with your city needs and reservations. 

Concierge Desk Hours 

Sunday through Saturday 9:00 am – 5:00 pm 


20 


Continuing Medical Education 

Accreditation Statement 

This activity has been planned and implemented in accordance 

with the Essential Areas and policies of the Accreditation 

Council for Continuing Medical Education (ACCME) through the 

joint sponsorship of Indiana University School of Medicine and 

the American Society of Gene & Cell Therapy. Indiana University 

School of Medicine is accredited by the ACCME to provide 

continuing medical education for physicians. 

NOTE: Sessions marked with an asterisk (*) are not part of the 

CME program. 

Designation Statement 

Indiana University School of Medicine designates this live 

activity for a maximum of 28.5 AMA PRA Category 1 Credits. 

Physicians should only claim credit commensurate with the 

extent of their participation in the activity. 

CME Certificates 

Participants requiring CME certificates must go to the 

Registration Desk and complete a CME form. CME certificates 

will be mailed to participants after the meeting. There is a CME 

fee of $65 USD for the 14 th Annual Meeting. 

Disclosure 

In accordance with the Accreditation Council for Continuing 

Medical Education (ACCME) Standards for Commercial Support, 

educational programs sponsored by Indiana University School 

of Medicine (IUSM) must demonstrate balance, independence, 

objectivity, and scientific rigor. All faculty, authors, editors, 

and planning committee members participating in an IUSMsponsored 

activity are required to disclose any relevant financial 

interest or other relationship with the manufacturer(s) of 

any commercial product(s) and/or provider(s) of commercial 

services that are discussed in an educational activity. 

Note 

While it offers CME credits, this activity is not intended to 

provide extensive training or certification in the field. 

Educational Methods and Materials 

Lectures, Case Presentations, Panel Discussions, Question and 

Answer Sessions, Audio/Video Presentations, Abstracts, Posters 

Educational Objectives 

At the conclusion of the activity, the participant should be able to: 

• Provide advice to patients who inquire about the potential 

of gene and cell therapy or the availability of open clinical 

trials, based on their exposure to the current clinical trials in 

gene and cell therapies. 

• Review state-of-the-art basic science and clinical trials data 

presented at this meeting with students in medical school 

and other health venues. 

• Use the latest advances in gene and cell therapy to enhance 

their research mission, as physician scientists conducting 

basic and clinical research. 

• Demonstrate improved regulatory compliance in conducting 

gene and cell therapy clinical trials, through exposure to NIH 

and FDA faculty during the educational program. 

Evaluation Method 

Evaluation by questionnaire will address program content, 

presentation, and possible bias. 

Needs 

Clinical gene transfer has become more and more complex 

due to ongoing developments in the fields of gene and cell 

therapy itself, together with bioethics, research integrity, and 

financial conflicts, as well as federal mandates, regulations 

and guidelines. Oligonucleotide Therapies, Novel Vector 

Development, Host-Vector Interactions and Vaccine Therapies 

will be discussed as well as many other scientific topics. This 

meeting will provide an educational forum for scientists 

and clinicians to expand their knowledge about the broad 

developments in these fields. 

Target Audience 

The target audience includes basic science and translational 

researchers, clinical investigators, physicians, postdoctoral 

fellows, graduate students, employees of federal government 

and regulatory agencies, and other healthcare professionals 

with an interest in the latest advancements in the field of gene 

and cell therapy. 



Dates 

The ASGCT 14 th Annual Meeting will begin the morning of 

Wednesday, May 18 and continue through the evening of 

Saturday, May 21, 2011. Exhibits will be open Wednesday, May 

18 through Friday, May 20. 

Exhibits 

Exhibits will be located in Exhibit Hall 4B, Level Four, of the 

Washington State Convention Center. The companies, 

organizations and institutions exhibiting at the ASGCT Annual 

Meeting will be providing you with the latest information on 

products and services directly related to your professional needs, 

as well as recruiting for open positions. An Exhibit Hall Social will 

be held on Wednesday evening and a coffee social will be offered 

on Thursday and Friday in the exhibit hall. All participants are 

urged to allow adequate time in your daily schedule to visit the 

exhibits, as they are an integral part of the success of the meeting. 

Exhibit Hall Hours 

Exhibits will be open Wednesday, May 18 through Friday, 

May 20, 2011. 


Thursday, May 19 10:15 am – 11:00 am 


Friday, May 20 9:15 am – 10:00 am 


Guest Attendance 

ASGCT asks registered attendees to refrain from taking children, 

spouses, or guests to any educational session or functions 

offered at the 14 th Annual Meeting. 

Internet Access & Policy 

Internet access will be available at the Washington State 

Convention Center to all meeting attendees. Limited computer 

stations will be provided in the South Lobby, outside Hall 4B. 

When others are waiting at the internet kiosks, please limit your 

Internet use to 15 minutes at a time so other attendees can 

access the internet as well. 

Job Bank 

At the 14 th Annual Meeting, there will be a forum for academic 

institutions and companies to promote open positions to 

meeting attendees. If you have open positions, please bring 

multiple copies of your job posting to the meeting. Similarly, 

if you are seeking a job, please bring multiple copies of your 

résumé to submit. ASGCT will not take responsibility for 

résumés sent to the ASGCT office in response to a job posting. 

If you would like more information about this service, please 

contact Erin Hankey at ehankey@asgct.org. The Job Exchange 

area will be located inside Exhibit Hall 4B. 

Lead Retrieval 

A lead retrieval system has been made available to all exhibitors 

of the ASGCT 14 th Annual Meeting. Exhibitors may ask to scan 

attendee name badges with a hand held scanner in order to 

obtain attendee contact information. 

Location 

• The 14 th Annual Meeting will be held at the Washington 

State Convention Center, 800 Convention Place, Seattle, WA 

98101, USA. 

• Exhibits and Posters will take place in Hall 4B – Level Four. 

• Registration will be located in the South Lobby, just outside 

Hall 4B – Level Four. 

Materials Distribution 

Please refrain from distributing promotional materials 

throughout the meeting; these may only be distributed from an 

exhibit booth in Hall 4B – Level Four. 

Media 

Members of the working media may register for the 14 th Annual 

Meeting in the Press Room – Room 309 (Level Three). Interview 

space, computers and internet services are available for the 

convenience of media representatives covering the meeting. 

Press must register, provide credentials, and wear their press 

badge for admittance to ASGCT sessions. Assistance will be 

provided to members of the media that would like to schedule 

interviews. 

No Smoking 

Smoking is prohibited at all 14 th Annual Meeting sessions 

and events. 


22 


Posters 

Abstract Posters will be on display in Hall 4B (Level Four). 

Thursday, May 19 

Abstract Poster Session I 

10:00 am – 12:00 pm Poster Setup by Authors 

1:00 pm – 6:40 pm Poster Viewing 

(authors present from 4:40 pm – 6:40 pm) 

4:40 pm – 6:40 pm Exhibit Hall Open: Networking Reception, 

Exhibits, and Poster Session 

6:40 pm – 7:00 pm Authors Remove Posters 

Friday, May 20 

Abstract Poster Session II 




4:40 pm – 6:40 pm Exhibit Hall Open: Networking Reception, 

Exhibits, and Poster Session 


Saturday, May 21 

Abstract Poster Session III 




6:15 pm – 8:15 pm Poster Session 


Call4Posters® Pick-up Schedule 

This year the ASGCT arranged with Marathon Multimedia to 

provide poster authors with the opportunity to create their 

poster online using the Call4Posters® service. Poster presenters 

who took advantage of this service may pick-up their preordered 

poster at the ASGCT Registration Desk during the 

following hours. 

Tuesday, May 17 5:00 pm – 7:00 pm 

Wednesday, May 18 7:00 am – 8:00 pm 

Thursday, May 19 7:00 am – 5:00 pm 

Friday, May 20 7:30 am – 5:00 pm 

Saturday, May 21 7:30 am – 5:00 pm 

Press Room 

The Press Room is located in the Washington State Convention 

Center, Room 309 (Level Three). 

Press Room Hours 





Registration Desk 

Name badges, final programs, and abstract supplements will be 

distributed at the registration desk located outside of Hall 4B, in 

the South Lobby of the Washington State Convention Center. 

Registration Desk Hours 






Cancellation Refund Policy 

Refund requests should have been submitted in writing to the 

ASGCT Executive Office prior to May 9, 2011. A $35 processing fee 

will be charged for all refunds. We regret that refunds cannot be 

allowed for requests postmarked or received after May 8, 2011. 

Seattle Information 

Please note, the City of Seattle issues jaywalking tickets to 

individuals who do not follow the traffic laws. Therefore, please 

abide by the traffic signs and lights and utilize the designated 

crosswalks at all times. See Seattle Fun Facts on page 85 for 

more information on Seattle. 

Shuttle Bus 

ASGCT will not be providing shuttle transportation for the 

14 th Annual Meeting. The Washington State Convention Center 

is located within 1-4 blocks of the ASGCT Annual Meeting 

hotel block. 



Speaker Ready Room 

There will be a Speaker Ready Room located in the Washington 

State Convention Center, Room 613-614 (Level Six). 

All faculty, including oral abstract presenters, must deliver 

their presentations to the Speaker Ready Room the day before 

their session or at least four hours prior to their presentations. 

Equipment is available for faculty to review their materials. 

Audiovisual personnel will be available for assistance. Please 

mark your materials (your name, session and speaker order) 

so the materials can be returned to you. The Society strongly 

encourages faculty to pre-load presentations in the Speaker 

Ready Room; those faculty who load presentations in the 

meeting rooms during the sessions will have that time 

deducted from their presentation time by the Chair. 

ASGCT strongly encourages faculty presenting on Wednesday 

of the Annual Meeting to check in at the Speaker Ready Room 

on Tuesday, May 17 to avoid congestion. 

Avoid delays and check-in early! 

Speaker Ready Room Hours 






Special Accessibility Needs 

If you require special accommodations under the ADA in order 

to fully participate in the meeting or the course, please visit the 

Registration Desk; ASGCT staff will be happy to assist you with 

your specific needs. 


24 

Washington State Convention Center 

Level 1 


Escalators 

Up to ASGCT 

Registration


Level 2 

Level 2 

• ASGCT Committee 

Meetings 

• Meet-the- 

Investigator Sessions 


26 


Level 3 

Level 3 

• Meet-the-Investigator 

Sessions 

• Press Room – Room 309 



Level 4 

Skybridge 

Friday Night 

Party 

Posters 

Exhibits 

Registration 

Level 4 

• Exhibit Hall - 4B 

• Internet Kiosks 

• Job Exchange 

• Poster Hall - 4B 

• Registration Desk 

• Friday Night Party 

- Skybridge 


28 


Level 6 


Level 6 

• Plenary Lecture Hall - 6BC 

• Session Rooms 

(Education, Oral Abstracts, 

Scientific Symposia) 

• Speaker Ready Room 

(Room 613-614) 

• Committee Meetings

Schedule-at-a-Glance (This program is subject to updates/changes) 

Tuesday, May 17 

5:00 pm - 7:00 pm Registration Open 

Wednesday, May 18 

7:00 am - 8:00 pm Registration Open 

7:30 am - 8:00 am Coffee Break 

8:00 am - 10:00 am Scientific Symposia Session I 

10:30 am - 12:00 pm Education Session I 

12:00 pm - 1:15 pm Lunch Break (On Own) 

1:15 pm - 2:45 pm Education Session II 

3:15 pm - 5:15 pm Oral Abstract Session I 

5:15 pm - 7:15 pm Exhibit Hall Welcome Reception 



8:00 am - 10:15 am Presidential Symposium 

Keynote Speaker: George Q. Daley, MD, PhD: Towards Combined Gene and Cell Therapy with Pluripotent Stem Cells 

10:15 am - 11:00 am Exhibit Hall Coffee Social 

11:00 am - 1:00 pm Scientific Symposia Session II 


1:00 pm - 2:30 pm Meet-the-Investigator Sessions 

1:00 pm - 6:40 pm Poster Viewing (Authors present from 4:40 pm – 6:40 pm) 

2:30 pm - 4:30 pm Oral Abstract Session II 

4:40 pm - 6:40 pm Exhibit Hall Open: Networking Reception & Poster Session I 



8:00 am - 9:15 am George Stamatoyannopoulos Lecture 

Keynote Speaker: Victor J. Dzau, MD: Paracine Mechanisms of Stem Cell Action in Tissue Repair and Regeneration 

9:15 am - 10:00 am Exhibit Hall Coffee Social 

10:00 am - 12:00 pm Scientific Symposia Session III 



1:15 pm - 3:15 pm Oral Abstract Session III 

3:45 pm - 4:30 pm Outstanding Achievement Award Lecture 

Keynote Speaker: Malcolm K. Brenner, MD, PhD: Cell and Gene Therapy - Putting it Together 

4:40 pm - 6:40 pm Exhibit Hall Open: Networking Reception & Poster Session II 

7:00 pm - 9:00 pm Friday Night Party 



7:30 am - 8:00 am ASGCT Business Meeting (with continental breakfast) 

8:00 am - 9:45 am Outstanding New Investigator Symposium 

10:15 am - 12:15 pm Oral Abstract Session IV 


12:15 pm - 1:45 pm Meet-the-Investigator Sessions 


1:45 pm - 3:45 pm Scientific Symposia Session IV 

4:15 pm - 6:15 pm Scientific Symposia Session V 

6:15 pm - 8:15 pm Poster Session III 

8:15 pm Annual Meeting Concludes 



30 

Program Schedule Wednesday, May 18, 2011 

SCIENTIFIC SYMPOSIUM 100 

8:00 am - 10:00 am 

Room: 615-617 

Challenges in the Development of Investigational Gene and Cell Therapy Products: 

Perspectives from Multi Center Trials 

Jointly planned by the Association of Academic Biologics Manufacturers 

CO-CHAIRS 



SPEAKERS 


Can Cell Transfer Therapy Move From Wall Street to Main Street? 

Given that cell and gene therapies are beginning to work in a number of phase I trials, the next challenge becomes how to 

progress to the next step in clinical development? In this session, the approach that we have taken to conduct multicenter 

studies with personalized, patient specific T cells in patients with cancer will be discussed. The field must demonstrate that robust 

manufacturing technologies are in place in order to support the eventual wide spread application and FDA approval of therapies 

with customized cell and gene therapy products. 

Mitchell H. Finer, PhD 

Lessons Learned from Lentiviral Gene Transfer into Bone Marrow in Two Clinical Trials: Planning a Multi-Center 

International Study Leading to Product Registration 

Bluebird Bio (formerly Genetix Pharmaceuticals) gained significant experience over the past five years in the clinical development of 

Lentiviral gene therapy products for the treatment of monogenic diseases in the context of autologous bone marrow transplant. The 

company is currently the sponsor of a Phase I/II study for evaluation of genetic therapy of Hemoglobinopathies (β-thalassemia and 

sickle cell anemia) following gene transfer of a functional human β-globin gene into autologous CD34+ cells, currently being carried 

out in Paris. The 34 month follow-up of the first patient were published in Nature in November 2010 (Cavazzana-Calvo et al,. 2010, 

Nature 467:318-322) by Philippe Leboulch and Marina Cavazzana-Calvo. The company’s collaborators Patrick Aubourg and Nathalie 

Cartier published the results describing two year follow-up of two boys treated in a Phase I/II study for the treatment of the childhood 

cerebral form of Adrenoleukodystrophy (ALD) through ex vivo transfer of the ALD cDNA into autologous CD34 cells, sponsored by 

INSERM, in Paris (Cartier et al., 2009, Science 326:818-823). Working together with an international group of collaborators in the US and 

France and the experience gained from these Lentiviral clinical trials, the company is undertaking the planning and launch of a single, 

multi-center study designed to register a Lentiviral gene therapy-based product to be used in the context of autologous bone marrow 

transplantation for the treatment of the childhood cerebral form of ALD. The application of lessons learned from the previous two 

studies and how they facilitated the design and implementation of the upcoming international multi-center study will be presented. 


John T. Gray, PhD 

Paper to Patient in 4 Years: Development of a Self-Complementary Serotype 8 AAV Vector for Treatment of Hemophilia B 

for a Multi-Center Clinical Trial in the United States and United Kingdom 

The manufacture of clinical grade adeno-associated virus vectors remains significantly challenging, with little consensus as to either 

“best practices” for the manufacturing process or clearly defined biochemical assays for ensuring final product potency. Since our 

publication in 2006 of a novel, self-complementary AAV vector expressing a codon-optimized human Factor IX gene, we have 

transitioned this vector into large scale GMP production, and gained regulatory approval in both the US and the UK for the use of 

the resulting clinical vector in adult Hemophilia B patients. In this Symposium presentation I will summarize our vector production 

process, product certification, and regulatory approval. Details will be provided for multiple analytical assays that we have 

developed for monitoring product quality, including our observations that quantitative PCR assays can dramatically underestimate 

the vector genome titer of self-complementary AAV vectors. 



PANEL 

Estuardo Aguilar-Cordova, PhD 


Daniel M. Takefman, PhD 


8:00 am - 10:00 am 

Room: 6A 

Gene & Cell Therapy Around the Globe: A Showcase of Europe 

Jointly planned with the European Society of Gene and Cell Therapy 

CO-CHAIRS 

Thierry C. VandenDriessche, PhD 

Seppo Ylä-Herttuala, MD, PhD, FESC 

SPEAKERS 

Paolo Macchiarini, MD, PhD 

Stem-Cell Based Restoration and Replacement Therapies for Irreversible Diseases of the Airway 

The ramifications of stem cell research and therapy for irreversible diseases of the airway are enormous. We provided evidence 

that mesenchymal stem and autologous (respiratory) cells can be successfully used to reseed, either ex-vivo or in-vivo, laryngotracheal 

and tracheal human bioengineered scaffolds, and that this can successfully replace major airway in children and adults. 

However, adult stem cells have remarkable abilities to self-renew and differentiate into one or multiple types of mature cells, and 

that they commonly reside in specific local microenvironement, called niche. Since they have been found as well in the airway, why 

not speculate to use stem cell therapy for restoring cell, tissue or organ function in patients with otherwise untreatable airways 

diseases instead doing, and therefore avoid tissue-engineered transplantation? We currently have an ongoing phase I clinical trial 

that recruits and mobilizes both, dormant or silent stem cells and progenitors cells from the periphery to repair untreatable tissues 

or organs. This nearly eliminates any ethical or religious arguments to the stem cell treatment, and regulations. All this research will 

be presented. 

Sebastien Maury, MD, PhD 

Regulatory T-cell Depletion to Improve the Graft-Versus-Tumor Effect of Donor Lymphocytes after Allogeneic 

Hematopoietic Stem Cell Transplantation 

Donor T-cells play a pivotal role in the graft-versus-tumor (GVT) effect after allogeneic hematopoietic stem cell transplantation 

(HSCT). In the setting of donor lymphocyte infusion (DLI) after HSCT, we postulated that Treg depletion could improve alloreactivity 

and likewise the GVT effect of donor T-cells. In alloreactivity-resistant patients, we show that Treg-depleted DLI is a safe 

approach which induces GVT effect. In patients not responding to this approach, the combination of a chemotherapy-induced 

lymphodepletion of the recipient synergizes the effect of Treg-depleted DLI. Our findings offer a new rational therapeutic approach 

for cancer cellular immunotherapy. 


Cell Transplantation Strategies for Repairing the Retina 

We have previously discovered that transplantation of rod precursor cells at a specific stage of development results in their 

integration and subsequent differentiation into rod photoreceptors that form synaptic connections and improve visual function 

in mouse models of retinal degeneration (MacLaren, et al Nature, 2006). Conversely, transplantation of progenitor or stem cells 

that are not at this precise ontogentic stage do not show this property and fail to integrate. These findings provide a strong basis 

14TH ANNUAL MEETING | SEATTLE, WA | MAY 18-21, 2011 31 

Wednesday, May 18


32 


for the development of a cell transplantation programme for the treatment of retinal disease. We are also developing strategies 

to overcome barriers present in the degenerate neural retina in order to improve the efficiency of cell integration and are testing 

efficacy using electrophysiology and various behavioural assessments of vision. Recently it has been shown that it is possible to 

generate photoreceptor cells from embryonic stem cells (Lambda et al PNAS 2006, Osakada Nat Biotech 2008) and our current 

work is focused on using embryonic stem cells to generate rod progenitors cells for transplantation. 

Dominic J. Wells, PhD 

Translational Studies in Duchenne’s Muscular Dystrophy 

The presentation will briefly review the range of experimental therapeutic options for the lethal muscle wasting disorder, 

Duchenne muscular dystrophy. It will then focus on antisense mediated exon-skipping to restore the open reading frame of the 

dystrophin mRNA. Recent clinical trials will be discussed together with the possible factors limiting the efficiency of systemic 

delivery of antisense reagents. Potential solutions to increase efficiency will be proposed in the light of pre-clinical experiments. 

Finally the role of the immune response in the context of exon-skipping and treatment of DMD in general will be evaluated. 


8:00 am - 10:00 am 

Room: 611-612 

Immunosuppression for Gene and Cell Therapy 

CO-CHAIRS 



SPEAKERS 

Rainer F. Storb, MD 

Conditioning for Transplantation of Hematopoietic Stem Cells 

Allogeneic hematopoietic cell therapy requires crossing a double immunologic barrier, host-versus-graft reaction and graft-versushost 

reaction. In order to accomplish the former, conditioning regimens have been developed that range in intensity from high, 

otherwise lethal doses of body irradiation or chemotherapy to use of non-toxic radiolabeled monoclonal antibodies or T-cell 

costimulatory blockade. The latter requires administration of immunosuppressive agents for 6-12 months after allogeneic cell 

transplantation, usually a combination of an anti-metabolite and a calcineurin inhibitor. During that time, tolerance of graft against 

host becomes established in a majority of patients. 


Immune Modulation to Promote Tolerance in Gene and Protein Therapies 

Adaptive immune responses against therapeutic proteins limit efficacy of gene and protein replacement therapies for genetic 

diseases. It is therefore desirable to develop immune tolerance protocols for the specific protein antigen. This can be accomplished 

using specific routes/modes of antigen administration, tolerogenic gene transfer protocols, or administration of a combination 

of antigen and immune modulatory drugs (as well as drugs that limit inflammatory signals). Such strategies may also be helpful 

in reversing existing immune responses. Immune tolerance induction to coagulation factors in treatment of hemophilia will be 

discussed as an example for employment of such strategies. 


Gene and Cell Based Therapies for Autoimmune Diseases 

Gene therapy approaches for treating autoimmune disorders such as rheumatoid arthritis and type I diabetes have shown 

significant efficacy in numerous animal models. The effective approaches include ex vivo methods involving genetically modified 

dendritic cells (DC), exosomes derived from genetically modified DC as well as direct, in vivo gene transfer of immunomodulatory 

cytokines to joints and to endogenous islets. We have performed several clinical trials for gene therapy of rheumatoid arthritis 

using intra-articular injection of genetically modified synovial fibroblasts expressing IL-1Ra. Currently we are developing AAV-based 

approaches for treating osteoarthritis by intra-articular gene transfer of IL-1Ra. The significant pre-clinical and clinical progress 

made towards developing viable gene therapy approaches for treating autoimmune disorders using rheumatoid arthritis and type 

1 diabetes as model autoimmune diseases will be presented. 



Doina Ganea, PhD 

Genetically Altered Myeloid Dendritic Cells Secreting Immunosuppressive Neuropeptides as Therapy for Inflammatory/ 

Autoimmune Conditions 

Dendritic cells (DC) initiate immune responses as well as tolerance. We showed previously that the neuropeptide vasoactive 

intestinal peptide (VIP) suppresses innate immune responses, generates tolerogenic dendritic cells, and has therapeutic effects 

in models of autoimmune/inflammatory disorders. To generate tolerogenic DC that also provide VIP locally, we used lentiviral 

vectors to engineer VIP-expressing DC. LentiVIP-DC secrete VIP, switch from a proinflammatory to an anti-inflammatory cytokine 

profile and lose the capacity to activate T cells. A single inoculation of LentiVIP-DC in sepsis and MS models had therapeutic effects. 

Local delivery of VIP by LentiVIP-DC may represent a promising therapeutic tool for the treatment of autoimmune diseases and 

inflammatory disorders. 

Education Sessions 

The goal of the ASGCT Education Program is to provide participants with a broad background and introduction to topics relevant 

to the field of gene and cell therapy. Education Sessions will be subdivided into two headings. “Topical Review” sessions will 

provide a broad perspective of an area of importance to the gene and cell therapy community such as major vector systems, 

specific target organs or diseases, and funding/regulatory issues. “Emerging Field Review” sessions will provide a broad perspective 

of a technological or scientific discipline that has recently become of great significance to ASGCT members. 

EDUCATION SESSION 110 

10:30 am - 12:00 pm 

Room: 6A 

Emerging Field Review: Genomics (Personalized Medicine) 

CHAIR 


SPEAKERS 

John J. Nemunaitis, MD 

Clinical Development of GNE Gene Lipoplex Therapy in Hereditary Inclusion Body Myopathy 

Hereditary Inclusion Body Myopathy (HIBM) is an autosomal recessive adult onset myopathy due to mutations in the GNE (UDP- 

N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase) gene. Affected patients have no therapeutic options. A single 

patient with severe HIBM treated via single patient IND safely received seven escalated doses of GNE gene lipoplex via intravenous 

infusion. Quadriceps muscle expression of the delivered GNE, plasmid and RNA were observed 24 hours after the 5.0 mg dose and 

at significantly greater levels 72 hours after the 7.0 mg infusion in comparison to expression in quadriceps muscle immediately 

before infusion. Clinical safety and activity is demonstrated with intravenous infusion of GNE gene lipoplex supporting further 

assessment involving Phase I trial. 

Stanley Riddell, MD 

Functional Heterogeneity in T Cell Subsets - Implications for Adoptive Immunotherapy with Genetically Re-targeted T Cells 

The adoptive transfer of T cells that are isolated from the blood and retargeted to recognize tumor cells by transferring genes that 

encode an αβ T cell receptor or a chimeric antigen receptor is a rapidly emerging therapy for human malignancy. The simplest 

iteration of this approach is to genetically modify peripheral blood T cells that have not been selected based on any particular 

phenotypic or functional properties. In this presentation, we will discuss the rapid evolution in our understanding of heterogeneity 

within human peripheral blood T cells, which includes subsets that are distinctly programmed for survival and inflammatory 

cytokine production, and suggests that selection of defined populations for gene modification may be necessary to fully capitalize 

on the opportunities for cancer immunotherapy. Clinical investigation of defined cell populations will require the development of 

improved cell selection technologies that do not compromise function. It is also imperative that future clinical trials incorporate 

detailed characterization of the cell products that are infused and sophisticated monitoring of their fate, migration and function in 

vivo in each patient, to provide insight into the basis for therapeutic success and toxicity, and direct subsequent investigation. 


Wednesday, May 18


34 


Kevin M. Flanigan, MD 

Identifying Patient-Specific Mutations in the DMD Gene: Implications for Phenotype and Therapies 

New methods of molecular diagnosis have facilitated the identification of rare or unique mutations in the DMD gene that result 

in the dystrophinopathies Duchenne and Becker Muscular Dystrophy. Cataloging these mutations has widened the mutational 

spectrum associated with these diseases, and has led to the increased recognition of certain mutational classes. New data has 

emerged to explain the mechanisms by which mutations predicted from genomic testing to result in reading frame termination 

are instead associated with expression of partially functional dystrophin and a milder disease course. These mechanisms may 

have implications for the implementation of therapies already in clinical trials, including nonsense mutation suppression, exon 

skipping, and gene replacement. In this talk I will summarize diagnostic advances, review molecular mechanisms of phenotypic 

amelioration, and discuss the therapeutic implications for Duchenne Muscular Dystrophy. 


10:30 am - 12:00 pm 

Room: 608-609 

Emerging Field Review: HIV Gene Therapy 

This session will discuss the biology of HIV-1, the practicalities of performing clinical trials in HIV patients and latest results from 

both T cell and stem cell based trials. Dr. Paula Cannon will introduce the session by describing key features of the HIV-1 lifecycle 

and cellular anti-viral defenses that are being exploited in gene therapy approaches and the use of humanized mouse 

models for pre-clinical evaluation. Dr. Carl June will describe T cell based gene therapies, including an update of ongoing T cell trials 

using zinc finger nucleases directed against CCR5. Dr. Dave DiGiusto will focus on some of the practical aspects of running a clinical 

trial, in particular the isolation and manipulation of hematopoietic stem cells from HIV-infected patients. 

CHAIR 


SPEAKERS 


Targets and Tools for anti-HIV Gene Therapy 

This talk will provide an introduction to anti-HIV gene and cell therapies. Features of the HIV-1 life-cycle and cellular antiviral 

defenses that can be exploited by gene therapy will be highlighted, as well as progress in the use of humanized mouse 

models for pre-clinical evaluation. The application of zinc finger nucleases targeting the CCR5 co-receptor to engineer 

hematopoietic stem cells will be described. 


T Cell Engineering for HIV - Update 

The development of HIV therapy has been a triumph in that a formerly universally fatal infection is now managed by a cocktail of 

antiretroviral drugs that prevent progression the infection. The challenge to the field is that the current therapies are not curative, 

and that even with the best antiviral therapies, the present therapies are not curative since the reservoir of HIV infection is not 

reduced, and a significant morbidity from the infection and the treatment remain. New cell and gene therapy based approaches 

have the potential to address this shortfall, and should be focused on the development of transformative therapies that are 

potentially curative. The results from a pilot trial using CCR5 deficient T cells will be reviewed as an example of the new cell and 

gene therapies that are on the horizon. 

David L. DiGiusto, PhD 

Gene Therapy for HIV, Progress, Promise and Practicality 

Stem cell-based gene therapy for HIV has been under investigation for over 20 years and offers great promise as a “functional 

cure” for AIDS. Among the many issues for this type of therapy are questions related to best therapeutic entity, gene delivery to 

stem cells, preparative regimen for transplant, persistence of cells in vivo and the potential for treatment related malignancies. 

This session will focus on the practical aspects of stem cell isolation, genetic modification and transplant and feature a review of 

published data that outline the problems encountered and potential solutions. At the completion, participants will have a better 

understanding of the advantages and limitations of gene modified stem cell therapies and potential pathways forward in this 

intriguing field of investigation. 




10:30 am - 12:00 pm 

Room: 606-607 

Topical Review: Cellular Based Therapies 

To date, stem cell therapies have focused on hematopoietic stem cells used in patients with malignancies or marrow failure, 

and requiring high dose conditioning regimens to prepare the recipient. The majority of these transplants were done using 

cells collected from related donors. In this session we will describe other indications for stem cell based therapies such as nonmalignant 

hematologic disorders, the use of nonmyeloablative regimens and the use of alternative, ie non-related donors. Finally 

we will discuss the use of stem cell therapy in a non-hematologic setting. 

CHAIR 

Elizabeth Kang, MD 

SPEAKERS 

John F. Tisdale, MD 

Nonmyeloablative Transplantation for Non Malignant Hematologic Disorders 

HLA-matched allogeneic hematopoietic stem cell transplantation is an established curative approach to children with sickle cell 

disease. Disease burden in has historically prohibited this approach in adults due to anticipated excess toxicity. This talk will focus 

on new conditioning regimens that we have recently developed that allow safe and effective application in adult patients. The 

limitations of this and other approaches will be discussed, along with new areas of research, including the development of haploidentical 

transplantation strategies. 

Brenda M. Sandmaier, MD 

Nonmyeloablative Regimens for Alternative Donor Hematopoietic Cell Transplantation 

Allogeneic hematopoietic cell transplantation can be a curative approach for patients with both malignant and nonmalignant 

hematopoietic diseases including immunodeficiency disorders and hemoglobinopathies. By introducing nonmyeloablative 

or minimal-intensity conditioning regimens, significant progress has been made in reducing transplant-related mortality. The 

reduction in toxicity has allowed us to extend allogeneic hematopoietic cell transplantation to older patients and those with 

comorbidities. Of equal importance, donor choices have been expanded by developing less toxic regimens for unrelated donors, 

HLA-haploidentical related donors, and unrelated cord blood grafts. Lastly, improvements in prophylaxis of graft versus host disease 

have contributed to the improved outcomes using alternative donors. 

Lindsey A. Muir 

Considerations for the Clinical Application of Myogenic Stem Cells in Muscular Dystrophy 

In the context of neuromuscular disorders such as Duchenne muscular dystrophy, many cell populations have been investigated 

for their potential to contribute to repair and regeneration of skeletal muscle. Some promising cell types will be discussed to 

illustrate important features that must be considered for eventual use in the clinic, including cell source, potency, engraftment 

efficiency, delivery, and evaluation of their contribution to muscle function following transplantation into animal models. 


10:30 am - 12:00 pm 

Room: 611-612 

Topical Review: Gene Therapy Strategies for Lysosomal Storage Diseases 

Lysosomal storage diseases (LSDs) are due to the primary genetic deficiency of a lysosomal enzyme, often causing accumulation 

of undegraded substrates within the lysosome that contributes to the disease phenotype. Viral-mediated gene therapy strategies 

have been developed for many of these diseases, several of which are currently in or close to the clinics. Common and specific 

aspects of these pathologies will be presented. Ex vivo and in vivo gene therapy approaches that are currently evaluated will be 

discussed. A special focus will be made on AAV and retroviral approaches. Results in animal models and clinical applications will be 

presented, particularly for mucopolysaccharidosis and metachromatic leukodystrophy. 

CHAIR 



Wednesday, May 18


36 


SPEAKERS 


Gene Therapy Strategies for Lysosomal Storage Diseases : General Aspects and Application to Metachromatic 

Leukodystrophy 

Metachromatic leukodystrophy is a severe neurodegenerative disease of the central nervous system due to the deficiency or aryl 

sulfatase A enzyme that leads to the accumulation of sulfatide in neurons and glial cells. Ex vivo gene therapy clinical application 

based on autologous transplantation of hematopoietic stem cells corrected with a lentiviral vector is currently ongoing. In situ 

delivery of AAV-ARSA vector to the brain has also been evaluated in animal models. Clinical application in rapidly progressive forms 

of the disease should be soon initiated. 


Targeting the CNS in Pompe Disease: Count Every Breath You Take 

The approval of enzyme replacement therapy for the severe form of muscular dystrophy know as Pompe disease has lead to a new 

natural history for a condition which previously lead to uniform mortality in infancy. New findings in an animal model and patients 

on current therapy have revealed a major component of the weakness is due to lower motor neuron dysfunction. In an effort to 

treat respiratory failure associated with neural dysfunction in Pompe disease, we have initiated a Phase I/II clinical study of AAVmediated 

replacement of the defective gene in order to target both the diaphragm and phrenic nerve responsible for respiration. 


Gene Therapy for Mucopolysaccharidosis 


10:30 am - 12:00 pm 

Room: 615-617 

Topical Review: Vector Design 

From the birth of gene therapy, research has been focused on the development of novel vector systems, and the optimization of 

existing ones. A major impetus has been the improvement of the efficiency of delivery and gene expression, but more recently, 

vector design has been found to also impact safety and manufacturing aspects of a gene therapeutic. Here, an overview is 

provided on the advances over the past decades in design of a viral gene transfer vector from envelope and capsid, to expression 

cassette components and transgene modifications. 

CO-CHAIRS 


Luk H. Vandenberghe, PhD 

SPEAKERS 


AAV and Adeno Vector Design 

Over the past decade, gene transfer vehicles based on engineered Adenoviruses (Ad) and Adeno-associated viruses (AAV) have 

consistently emerged as therapeutic vectors of choice for a broad range of genetic and chronic diseases in humans. Most recently, 

their already vast potential as recombinant in vivo gene and cell therapeutics has been further bolstered by continued progress in 

designing even safer, more efficient, more specific and hence more clinically applicable novel vector generations. Most notable 

advances include ingenious new approaches to re-program Ad vector tropisms using arrays of genetic and physical strategies, to 

develop gutless vectors devoid of all viral genes, or to directly develop the genuine viruses as cytotoxic agents for oncolytic viral 

therapies. Likewise, the already immensely broad utility and relevance of AAV vectors has recently been further expanded via the 

generation and selection of batteries of moleculary evolved synthetic capsids, by the engineering of self-complementary genomes 

for potent and persistent long-term RNAi expression, as well as by the exploitation of endogenous microRNAs as means to control 

vector tropism and to segregate AAV transgene expression. The aim of this educational lecture is to provide a comprehensive 

up-to-date overview over these exciting latest conceptual and technical advances in the fields of Ad and AAV vectors, supported 

by selected examples for the use of these newest promising vector generations for cancer treatments, gene correction and 

replacement strategies, iPS cell generation or in vivo RNAi-based therapies. 



Adrian J. Thrasher, MD, PhD 

Designing Retroviral Vectors for Reliable Gene Expression 

David W. Emery, PhD 

Safe and Effective Transgene Cassette Design 

This education presentation will focus on three aspects of safe and effective transgene cassette design. The first will entail a broad 

overview of the basic elements of an effective expression cassette, including the basic rules for promoters, coding sequences, 

RNA processing signals, and translational processing signals. The second will briefly cover some recent advances toward assuring 

constitutive or tissue-specific expression, including the use of specific promoter/enhancer elements, targets for tissue-specific 

microRNAs, and barrier chromatin insulators. The third will briefly cover some recent advances toward reducing the genotoxic 

potential of transgene expression cassettes, including the use of cellular or tissue-specific promoters, vectors with alternative 

integration site preferences, and enhancer-blocking insulators. Although specific examples will involve the setting of retroviral 

vectors, the underlying themes can be applied broadly to most gene transfer applications. 

LUNCH BREAK (ON OWN) 

12:00 pm - 1:15 pm 


1:15 pm - 2:45 pm 

Room: 6A 

Emerging Field Review: Cell Based Therapies Using ES/iPS Cells 

One of the most exciting advances in the recent years has been the discovery that somatic cells can be converted to 

pluripotent cells (called iPS cells) by the expression of a small number of defined transcription factors. The ability to generate 

iPS cells from somatic cells means that the ethical issues of deriving human embryonic stem cells from blastocysts has been 

circumscribed. There are important challenges, however, in translating the use of iPS cells to the clinic and in this session, the 

speakers will focus on several of these issues. 

CHAIR 

Matthew H. Porteus, MD, PhD 

SPEAKERS 

James Ellis, PhD 

Basic Issues in Creating iPS Cells 

The ability to reprogram somatic cells into induced pluripotent stem (iPS) cells has tremendous potential for developing novel 

cell based therapies. However, there are several basic issues that must be carefully addressed to generate and use clinical grade 

patient-specific iPS cells. Prior to reprogramming it is essential to obtain appropriate consent and decide on the best cell type 

to acquire from the patient. Ideally, the primary cells should be isolated and reprogrammed in xenogenic factor-free conditions 

using one of several methods that may be compatible with clinical use. Once iPS cell lines are expanded, their pluripotency status 

and differentiation capacity needs to be rigourously evaluated using well defined criteria, and concerns about their safety posttransplantation 

and the ability to track their progeny cells in vivo addressed. 

Charles E. Murry, MD, PhD 

ES/iPS Cells for Cardiac Repair 

Human embryonic stem cells and induced pluripotent stem cells (hESCs and hiPSCs) can be directed to differentiate into 

mesodermal cardiovascular progenitors and definitive cardiomyocytes using members of the TGF-b family (activin A and BMP4) 

and Wnt family. We have learned how to keep the cells alive after transplantation into infarcted hearts and shown that they form 

human myocardium that prevents the development of heart failure. Tissue engineering studies demonstrate that including 

stromal and vascular cells markedly enhances survival of myocardial tissue grafts. Endothelial and stromal cells self-assemble 

into networks, which form definitive blood vessels with connections to the host after transplantation. Current efforts are focused 

on electrical integration of human cardiac grafts, using genetically encoded calcium indicators to assess synchrony of beating 

between graft and host myocardium. 


Generation and Genetic Modification of Human iPS Cells 


Wednesday, May 18


38 



1:15 pm - 2:45 pm 

Room: 615-617 

Emerging Field Review: Progress in Gene Therapy for Pain 

Chronic pain represents a major cause of morbidity, significantly impairing individual quality of life and imposing a substantial 

burden on society. Numerous drugs such as NSAIDs and opioids have been approved for the treatment of chronic pain, yet 

they show limited efficacy either due to a lack of response to the drug regimen, or in most cases the patients develop tolerance 

to the drug, requiring ever increasing doses. The need for alternative therapies to treat chronic inflammatory and neuropathic 

painhas led to the development of gene therapy approaches using various viral (HSV, AAV, AdV, LV) and non-viral delivery systems. 

Vectors expressing inhibitory neurotransmitters (enkephalin, GAD65/67, ß-endorphin, endomorphin-2) or genes that modify 

neurotransmitters involved in nociception (glutamate transporter, µ-opiod receptor), trophic factors (NGF, BDNF, GDNF, HGF, VEGF), 

channels (Nav1.7, GlyR, Kir2.1) or a series of anti-inflammatory molecules (IL-4, IL-10, IL-2, TNFαsR) have been employed in a variety 

of animal models of persistent pain with remarkable success. Recently, two FDA-approved Phase-I trials for treating chronic pain 

ensued. The presenters in this session will cover the use of different vector systems and therapeutic gene products for treating 

chronic inflammatory and neuropathic pain in both animal models and finally in human Phase-I trials. 

CHAIR 

William F. Goins, PhD 

SPEAKERS 

Darren Wolfe, PhD 

NP2 Therapy for Severe Pain 

HSV vectors have proved effective at treating a large number of nervous system disorders in preclinical models. Target diseases 

include pain, neuropathy, cancer, and central nervous system diseases such as Parkinsons. Diamyd Inc has developed replication 

defective HSV vectors for clinical use and have recently completed our first clinical trial with intractable pain as an indication. 

Results of the study will be presented that demonstrate the safety of the platform as well as substantial and sustained pain relief in 

subjects with terminal cancer pain. 

Michel Pohl, PhD 

Lentiviral Vectors for Targeted Therapeutic Intervention into the Spinal Cord Glial Cells 

Clinical management of pathological pain, that frequently develops after alteration of peripheral nerves, remains challenging. 

We know today that neuropathic pain is associated with important changes of systems involved in pain processing, especially in 

the spinal cord where central afferents of sensory nerves project. Here, immune cell infiltration, glial activation and nerve tissue 

plasticity participate in induction of pain and its maintenance. This focal neuro-inflammatory context is associated with differential 

expression of many genes, production and release of signaling molecules and activation of various intracellular signaling pathways. 

The idea of local and possibly cell type specific intervention to modulate these systems and even to restore their physiologic 

function is tempting as a therapeutic option. This presentation will describe lentiviral-derived vectors as one of the promising tools 

for spinal cord local and cell targeted delivery of therapeutic molecules. 

Steven P. Wilson, PhD 

Controlling Pain by Herpesvirus-mediated Manipulation of Gene Expression in Primary Afferents 

A number of laboratories have exploited the natural tendency of herpes simplex virus to stably transduce sensory neurons, with 

the goal of changing the phenotypes of primary afferent, nociceptive neurons. The most commonly employed strategy is to use 

recombinant viruses designed to over-express antinociceptive peptides, such as enkephalins, in these neurons. Another strategy is 

to knock down expression of pronociceptive peptides using RNA interference methods. Additional strategies include manipulating 

the expression of receptors, ion channels or intracellular signaling molecules to modulate the activities of the primary afferents. 

The ultimate goal of these approaches is to develop therapies that will modulate pain. 




1:15 pm - 2:45 pm 

Room: 606-607 

Topical Review: Cancer Adoptive Immunotherapy with Genetically Modified Lymphocytes 

CHAIR 


SPEAKERS 


Genetically Modifying T cells to Target Tumors: It Starts with the TCR 

The use of strategies to characterize differential expression of proteins in tumors compared to normal cells has provided candidate 

antigens for targeting, and the development of methods to isolate and expand T cells recognizing such antigens has provided 

means to generate potential therapeutic reagents. However, most of these antigens represent normal self-proteins that are overexpressed 

by the tumor but still found in normal tissues, and thus most high avidity T cells have either been deleted or anergized. 

Strategies to isolate naturally occurring high affinity TCRs, including by rescue of tolerant T cells, or to mutate TCRs to improve 

affinity, and then express these TCRs in patient T cells to reproducibly provide a T cell reagent that can more effectively target 

human malignant cells will be discussed. Such T cells expressing introduced high affinity TCRs have the potential to mediate 

toxicity to normal tissues after transfer, and approaches to improve and screen for safety will also be discussed. 


Adoptive Therapy of Cancer with T cells Genetically Targeted to Tumor Associated Antigens through the Introduction of 

Chimeric Antigen Receptors (CARs): Trafficking, Persistence, and Perseverance 

A patient’s own T cells may be genetically modified to target tumor associated antigens (TAAs) through the introduction of genes 

encoding artificial T cell receptors termed chimeric antigen receptors. CAR modified T cells subsequently recognize tumor cells 

which express the targeted TAA in a non-HLA dependent manner. Promising pre-clinical studies using this approach has recently 

prompted the initiation of a series of early phase clinical trials at multiple centers using this technology and targeting a number 

of TAAs expressed on a wide variety of malignancies. Early reports from these clinical trials give hope for efficacy of this approach 

in the future, and provide insight into the optimal application of this therapy in second generation clinical trials. Specifically, CAR 

design, the tumor microenvironment, prior lymphodepletion, and in vivo modified T cell persistence will be discussed. 

Mirjam H.M. Heemskerk, PhD 

TCR Gene Therapy for Cancer 

TCR gene transfer is an attractive strategy to equip T-cells with defined antigen-specific TCRs using short-term in vitro procedures. 

Introduction of a well characterized high affinity TCR may result in an off-the shelf therapy with potent anti-tumor reactivity. 

However, some potential drawbacks to TCR gene transfer exist. TCR transfer leads to lower expression of the introduced TCR 

compared to parental T-cell clone due to competition for cell surface expression with the endogenous TCR and mixed TCR dimers. 

High affinity TCR are necessary to overcome this problem. High affinity TCRs directed against minor histocompatibility antigens 

and virus antigens are available, however identification of high affinity TCRs specific for tumor associated self-antigens is a critical 

bottleneck in this strategy. In addition, TCR transfer may lead to the formation of mixed TCR dimers, composed of introduced TCR 

chains pairing with the endogenous TCRα or ß chain, harbouring potentially harmful new reactivities. In this presentation the 

benefits and threats of TCR gene transfer and possible solutions will be presented. 


1:15 pm - 2:45 pm 

Room: 611-612 

Topical Review: Lessons from Large Animal Models in Gene Therapy 

The topical review session, entitled “Lessons From Large Animal Models in Gene Therapy,” will focus on the development and 

utilization of large-animal models in preclinical trials using lenti-, adeno- and AAV- based vectors for gene-therapy applications. The 

session will concentrate on the advantages and limitations of various large animal models as a means of studying the efficacy and 

safety of viral vectors in clinical trials. The session will comprise three talks: 


Wednesday, May 18


40 


CO-CHAIRS 

Tal Kafri, MD, PhD 


SPEAKERS 


Hematopoietic Stem Cell Gene Therapy in Large Animal Models 


Adenoviral Vectors in Non-Human Primates 

Nonhuman primates have been used extensively to evaluate adenoviral vectors for gene therapy. This education session will 

discuss why nonhuman primates are used, important lessons that have been learned as well as some associated pitfalls. Practical 

information for those contemplating research using nonhuman primates will also be discussed. 


The Challenge of Developing Animal Models of Human Gene Therapy with AAV 

Translation of gene therapy into the clinic relys on preclinical data, at least until there is a robust clinical experience with the 

platform vector technologies. Our experience is that vector efficacy in humans is well modeled in animals although host vector 

interactions are not. 


1:15 pm - 2:45 pm 

Room: 608-609 

Topical Review: Regulatory RNAs 

In this session we will hear from three renowned scientists about the latest insights emerging from studies of RNA biology and the 

newest technologies being developed to exploit these findings for gene and cell therapy. Dr. Anton McCaffrey will describe recent 

discoveries in RNA interference which are enabling better and safer applications of RNAi in the lab and in the clinic. Dr. Stephen 

Russell will detail the complex biology of microRNAs, and how this level of regulation can be used to control the tropism of viruses 

and vectors. Finally, Dr. Gabriele Varani will speak about some of the major new structural insights being uncovered about RNA 

binding proteins, and how these findings are helping to expand our global understanding of RNA regulation. 

CHAIR 


SPEAKERS 


Micro RNA Targeting of Oncolytic Viruses 

Anton P. McCaffrey, PhD 

RNA Interference Basics 

The purpose of this presentation is to provide a tutorial on RNA interference (RNAi). This will include background on the RNAi 

pathway as well as a discussion of opportunities for use of RNAi as a research tool and a therapeutic. Non-viral and viral approaches 

for delivery of RNAi will be covered. Limitations of RNAi and possible solutions will also be discussed. 

Gabriele Varani, PhD 

RNA-binding Proteins in Normal and Aberrant RNA Biogenesis 

The biogenesis of all cellular RNAs (mRNA, non-coding RNA, microRNA and stable nuclear species), rely on their association with 

RNA-binding proteins to control and regulate every maturation step. Because of their widespread role in gene expression, many 

human diseases are associated with mutation or aberrant expression in RNA-binding proteins. These proteins have modular 

structures, being composed of multiple repeats of just a few very frequent domains that are arranged in a variety of ways to satisfy 

their diverse functional requirements. The modules cooperate in regulating RNA binding and biological activity, and are often 

paired with enzymatic domains to regulate the catalytic activity of enzymes acting upon RNA. In this presentation, I will review the 

current knowledge of the structure function of these proteins and its relationship to normal and aberrant RNA biogenesis. 



ORAL ABSTRACT SESSION 130 

3:15 pm - 5:15 pm 

Room: 606-607 

Adenovirus and Other DNA Virus Vectors I: Virus Entry 

CO-CHAIRS 



(Abstracts 1-8; see page 87) 


3:15 pm - 5:15 pm 

Room: 6A 


CHAIR 




3:15 pm - 5:15 pm 

Room: 615-617 

Infectious Diseases and Vaccines 

CO-CHAIRS 





3:15 pm - 5:15 pm 

Room: 611-612 

Cancer-Targeted Gene & Cell Therapy I 

CO-CHAIRS 


Christine Brown, PhD 

(Abstracts 25-32; see pages 88-89) 


3:15 pm - 5:15 pm 

Room: 618-620 

Novel Approaches for Gene Regulation & Genome Modification 

CO-CHAIRS 





Wednesday, May 18


42 



3:15 pm - 5:15 pm 

Room: 608-609 

Genetic and Metabolic Diseases Gene & Cell Therapy I 

CO-CHAIRS 


Christopher Doering, PhD 



3:15 pm - 5:15 pm 

Room: 602-604 

Late Abstract Session 

CO-CHAIRS 




Exhibit Hall Open & Welcome Reception 

5:15 pm - 7:15 pm 

Room: Hall 4B 


Program Schedule Thursday, May 19, 2011 

PRESIDENTIAL SYMPOSIUM 200 

8:00 am - 10:15 am 

Room: 6BC 

Presidential Symposium 

CHAIR 


SPEAKERS 


Presidential Address 

George Q. Daley, MD, PhD 

Towards Combined Gene and Cell Therapy with Pluripotent Stem Cells 

A major goal of stem cell research is the creation of customized stem cells for use in disease modeling and as a foundation for 

autologous cell therapy. Understanding the principles of stem cell derivation, and defining whether embryonic stem (ES) cells 

and induced pluripotent stem (iPS) are equivalent remains a pressing issue. We have derived human and mouse ES cells and iPS 

cells from various human and mouse tissues, and compared their differentiation capacity and epigenome to determine whether 

iPS cells are functional and molecular equivalents of ES cells, and whether iPS cells retain an “epigenetic memory” of their tissue of 

origin. Aspects of iPS cell derivation from normal and diseased tissues will be discussed, as will data comparing ES and iPS cells. 

Presentation of Top Abstracts 


Abstract 49: In Vivo Delivery of Zinc Finger Nucleases Mediates Genome Editing to Correct Genetic Diseases 


Abstract 50: Demonstration of Safety and Antitumoral Activity of JX-594, a Targeted Multi-Mechanistic Oncolytic 

Poxvirus, Following Intravenous Infusion and/or Intratumoral Injections in Patients with Refractory Metastatic Cancers 

Serge Herson, MD 

Abstract 51: A Phase I Dose-Escalating Study of AAV1 - γ-Sarcoglycan Gene Therapy for Limb Girdle Muscular Dystrophy 

Type 2C 


Abstract 52: Efficient Long-Term Bodywide Expression of an AAV9-Minidystrophin in the Muscle and Heart of Young Adult 

GRMD Dogs after Intravascular Injection without Immune Suppression 


Thursday, May 19


44 


EXHIBIT HALL COFFEE SOCIAL 

10:15 am - 11:00 am 

Room: Hall 4B 


11:00 am - 1:00 pm 

Room: 6A 

Clinical Studies with Oligonucleotides 

CHAIR 


SPEAKERS 

Ryszard Kole, PhD 

Progress in Exon Skipping Therapy for Duchenne Muscular Dystrophy 

Oligonucleotide-induced exon skipping in human dystrophin pre-mRNA is being tested in animal models and in a clinical trial 

involving patients with Duchenne muscular dystrophy. Systemic delivery of AVI-4658, a phosphorodiamidate morpholino oligomer, 

shows that this compound induced skipping in dystrophin pre-mRNA in muscles of the affected individuals. As a result, the 

translation reading frame of the defective mRNA is repaired and dystrophin production is restored. Although patient response was 

variable, dystrophin levels reached up to 50% of normal level of this protein. 

Richard C. Becker, MD 

Current State of RNA Oligonucleotides as Regulatable Anticoagulants 

The management of patients with acute thrombotic disorders has been hampered by anticoagulants with a narrow therapeutic 

window for safety and efficacy. We have developed a factor IX/IXa aptamer and complementary reversal oligonucleotide, with a 

goal of filling an unmet need in clinical practice. Phase 1, 2a and 2b studies have been completed and will be presented at the 

American Society of Gene and Cell Therapy’s 14th Annual meeting. 

James D. Thompson, PhD 

Clinical Development of Synthetic siRNAs 

Quark Pharmaceuticals currently has three synthetic siRNAs in clinical development that include PF-655 licensed by Pfizer that is 

being evaluated in Phase 2 studies for two ocular indications, QPI-1002 that Novartis has taken an option to license that is being 

evaluated in Phase 2 studies for renal diseases, and QPI-1007 in Phase I/II studies that is being developed as a neuroprotective 

agent for eye diseases. Quark is also collaborating with Nitto Denko to develop siRNA therapies to treat fibrosis. Quark has 

developed proprietary chemical compositions that abrogate off-target and immunostimulatory activity while preserving RNAi 

activity. Nonclinical and clinical data from these various programs will be presented. 

Kim N. Chi, MD 

OGX-011: An Antisense Therapeutic Against Cluster in Clinical Development for Cancer 

Clusterin is an ATP-independent chaperone that promotes cancer cell survival through NF-kB and AKT signaling, inhibition 

of apoptosis through activated Bax and prevents stress-induced protein aggregation. OGX-011 is a second generation 

phosphorothioate antisense oligonucleotide with 2’-meothxyethyl modifications that potently inhibits clusterin expression in 

vitro, in vivo, and in humans. Phase 2 trials with OGX-011-chemotherapy combinations have been performed in patients with 

breast, lung and castration resistant prostate cancer (CRPC). In a randomized phase 2 study in patients with CRPC, the median 

overall survival for patients treated with docetaxel+OGX-011 was 23.8 vs. 16.9 months for those patients receiving docetaxel alone 

(HR=0.50; 95%CI: 0.29-0.87). Phase 3 studies with OGX-011 are now ongoing. 




11:00 am - 1:00 pm 

Room: 611-612 

Earlier Stage Industry Clinical Trials 

CHAIR 

William F. Kaemmerer, PhD 

SPEAKERS 

Douglas J. Jolly, PhD 

Alain Rolland, PharmD, PhD 

TransVax, a Therapeutic DNA Vaccine for Control of Cytomegalovirus in Hematopoietic Cell Transplant Recipients: 

Results of a Phase 2 Clinical Trial 

CMV reactivation occurs in 60-70% of CMV-seropositive hematopoietic cell transplant (HCT) cancer patients (with leukemia and 

lymphoma) within 6 months of transplant. Preemptive antiviral therapy limits CMV disease, but is accompanied by the risk of drug 

toxicity. Control of viremia is dependent on CMV-specific T cells and a vaccine that increases cellular immune responses could 

decrease CMV reactivation, reducing the need for antiviral drugs and risk of CMV disease. In a double-blind, placebo-controlled, 

exploratory Phase 2 trial, CMV-seropositive recipients of allogeneic HCT were administered TransVax, a CMV therapeutic DNA 

vaccine containing plasmids encoding CMV glycoprotein B (gB) and phosphoprotein 65 (pp65) formulated with poloxamer 

CRL1005 (n=42) or placebo (n=38) just before conditioning and at 1, 3, and 6 months after transplant. TransVax appeared to be 

safe and immunogenic, resulting in protection of HCT recipients from recurrent CMV viremia. This is the first successful proof-ofconcept 

trial of a CMV vaccine in HCT and the results support further development. 


Vaccines for Addictive Drugs 

Cocaine addiction is a major international problem for which there are no therapies. By taking advantage of the immunogenic 

properties of adenovirus gene transfer vectors and linking a cocaine analog to the capsid proteins, we have developed an anticocaine 

vaccine that prevents cocaine from reaching its receptors in the CNS. In a parallel strategy, we have modified adenoassociated 

virus vectors to genetically deliver an anti-cocaine monoclonal that also protects the brain from administered cocaine. 

Michael Kaplitt, MD, PhD 

AAV-GAD Gene Therapy for Parkinson’s Disease: Phase 2 Trial Results and Lessons Learned 


11:00 am - 1:00 pm 

Room: 608-609 

Emerging Conditioning and Hematopoietic Stem Cell Engraftment Strategies 

CHAIR 


SPEAKERS 


In Vivo Selection of Hematopoietic Stem Cells 

Louis M. Pelus, PhD 

Prostaglandines Enhance HSC Function: Strategies to Improve Transduced HSC Engraftment 

Prostaglandins and other members of the eicosanoid family play physiological roles in regulating hematopoietic stem and 

progenitor cell function. We have recently shown that prostaglandin E2 (PGE2) up regulates transcription and expression of 

the CXCR4 receptor on hematopoietic stem cells (HSC), as well as increasing expression of the endogenous caspase-3 inhibitor 

Survivin. PGE2 can also initiate self-renewal of HSC. Ex vivo treatment of mouse HSC, umbilical cord blood CD34+ cells as well as 

G-CSF mobilized peripheral blood CD34+ cells with PGE2 enhances migration in transwell cultures and engraftment of mouse 

HSC in congenic transplantation models and human CD34+ cells in immunodeficient mice. Blockade of prostaglandin signaling 

within the hematopoietic niche using non-steroidal anti-inflammatory drugs (NSAIDs) facilitates release of HSC and synergistic 


Thursday, May 19


46 


mobilization in combination with G-CSF. Application of these strategies offers the means to acquire more HSC for transduction 

protocols and to enhance function/engraftment of gene-transduced hematopoietic HSC. 

Alexander Kalinkovich, PhD 

Regulation of Progenitor Cell Mobilization, Homing and Repopulation via SDF-1/CXCR4 Interactions 

Success in clinical transplantation of hematopoietic stem/progenitor cells (HSPCs) depends on their efficient mobilization, homing 

and engraftment in the recipient’s bone marrow. The chemokine SDF-1 (CXCL12) and its major receptor CXCR4 together with 

adhesion molecules and proteolytic enzymes are key elements in HSPC quiescence, retention and trafficking. Disruption of HSPC 

retention by CXCR4 antagonists such as AMD3100 (Plerixafor) induces rapid HSPC mobilization, mediated by SDF-1 secretion to 

the circulation from bone marrow stromal cells and uPA activation. Clinical HSPC transplantation protocols require the recipient’s 

preconditioning with DNA damaging agents, which cause a dramatic and transient elevation in SDF-1 levels in the bone marrow, 

followed by SDF-1 cleavage and degradation by a wide range of proteolytic enzymes, thus providing appropriate conditions for 

efficient, time dependent homing and engraftment of transplanted CXCR4 expressing HSPCs. Recently discovered mechanisms of 

HSPC mobilization, homing and engraftment (repopulation) mediated by the dynamic SDF-1/CXCR4 interactions will be discussed. 

John M. Pagel, MD, PhD 

Radioimmunotherapy for Leukemias 

Recent developments in pretargeting and engineered and low-molecular weight agents in radionuclide therapy will be reviewed. 


11:00 am - 1:00 pm 

Room: 615-617 

Musculoskeletal Repair Mechanisms and Immune Obstacles 

CHAIR 

Jerry R. Mendell, MD 

SPEAKERS 

Christopher M. Walker, PhD 

Gene Delivery to the Muscle in Health and Disease 

The muscle is an important target for transgene delivery using recombinant adeno-associated virus (rAAV) vectors. T cell mediated 

immunity against encoded transgene products is a poorly understood but potentially important variable in the outcome of therapy. 

This presentation will review the nature of T cell responses elicited by rAAV-mediated gene delivery to muscle. Topics to be highlighted 

include (i) the function and differentiation of T cells primed by transgene products and (ii) the risk of developing a response when the 

therapeutic and defective host genes differ by a little (for example, a misssense mutation) or a lot (large frame-shifting mutations). A 

final point of discussion is whether T cell priming and effector function is equivalent when transgenes are delivered to healthy muscles 

versus those that are chronically inflamed in neuromuscular diseases like Duchenne Muscular Dystrophy. 

Annemieke Aartsma-Rus, PhD 

Learning from Exon Skipping Trials for Duchenne Muscular Dystrophy 

Antisense-mediated exon skipping is a promising therapeutic approach for Duchenne muscular dystrophy (DMD). It uses antisense 

oligonucleotides (AONs) to modulate pre-mRNA splicing so that a specific exon is skipped and the disrupted dystrophin reading 

frame restored allowing the production of internally deleted, partially functional dystrophins and potentially the conversion of a 

severe Duchenne into a milder Becker phenotype. This approach is currently in early phase clinical trials for two AON chemistries 

and targeting two different exons. While early results are encouraging, larger and longer trials are necessary to demonstrate clinical 

efficacy that AON treatment results in slowing disease progression and improving or maintaining muscle function in the absence 

of adverse effects. Furthermore, since exon skipping is a mutation specific approach, drugs to induce skipping of additional exons 

need to be developed as well to allow benefit of a large group of patients. 


The Use of Muscle Stem Cells for Musculoskeletal Repair 

I will discuss the use of muscle derived progenitor cells in gene therapy and tissue engineering applications designed to improve 

bone and articular cartilage healing through the genetic modification of MDSCs to express osteogenic proteins (BMP2 and -4) and 

the angiogenic factor VEGF. I will discuss potential features of these muscle progenitor cells including their potential relationship 



with other stem cell populations as well as behavior (resistance to stress) that may be useful to facilitate their isolation. I will 

describe mechanisms of action by which the cells induce tissue repair including the trans-differentiation of the cells as well as the 

chemo-attraction of the host cells during the repair process. I will also outline in my presentation new results obtained with human 

muscle derived stem cells, which we believe will open new avenues by which researchers could use muscle stem cell-based gene 

therapy and tissue engineering to improve bone repair and regeneration. 

Jay R. Lieberman, MD 

Novel Strategies to Enhance Bone Repair: Lessons Learned 

Regional gene therapy has been developed to enhance bone repair using a variety of different vectors in pre-clinical models. 

The data from these experiments have shed light on the influence of the duration and the amount protein expression on the 

enhancement of bone repair. Although the use of gene therapy to promote bone repair has clinical potential issues related to 

safety and cost effective strategies need further development. These issues will be reviewed during this seminar. 


11:00 am - 1:00 pm 

Room: 602-604 

Potential Use and Abuse of Genetic Testing in Personalized Medicine: Is it Premature? 

CHAIR 

Nelson Wivel, MD 

SPEAKERS 

Henry T. Greely, JD 

Open Questions in Genetically Personalized Medicine 

The use of genetic test results to personalize medicine has been a hot discussion topic for more than a decade. As their actual use 

now begins to become common, important questions remain unanswered. The questions are becoming even more challenging 

as genetic testing moves from single gene tests, to array-based comprehensive genomic hybridization, SNP chips, and ultimately 

full genome sequencing. This presentation will deal with several of those issues, including confidentiality, research uses, and 

informed consent. 

Eric Juengst, PhD 

Personalized Genomic Medicine: Ethical Conundrums 

“Personalized genomic medicine” (PGM) is being promoted as a “new paradigm for health care” and a major goal for translational 

genomic research. In addition to overcoming remaining scientific hurdles, achieving that goal will involve addressing a number 

of ethical, legal and social challenges. Some of those challenges reflect the ways that different social policies and health care 

economies will complicate our ability to realize PGM as a viable health care paradigm. But other challenges might emerge 

from the goal itself, depending on how PGM is interpreted by those who shape it as a social practice. PGM is a goal that unites 

a wide array of biomedical initiatives, from medical sequencing, gene expression, and pharmacogenomics research to public 

health, clinical, and commercial services. Its promissory virtues are precision diagnosis and risk prediction, individualized therapy, 

prevention, health promotion, and patient empowerment. Different proponents of PGM interpret and rank these promises 

differently, with different implications for the realization of PGM as a health care paradigm. As a result, the “translational pipeline” 

of genomic research will have many branches towards its distal end. The purpose of this project is to study how some of the most 

influential parties in promoting, implementing, providing and using “personalized genomic medicine” understand its promises 

and potential pitfalls, in order to draw out the policy choices that lie ahead for researchers, health care providers and the public as 

translational genomic research moves closer to its goal. 

Nancy M.P. King, JD 

Evaluating and Valuing Personalized Genomic Information 

This presentation addresses (1) the difficulty in interpreting risk information in personalized genetic screening and testing and 

(2) the contested meaning of risk as applied to the common complex disorders that are most often tested for currently and are 

probably of greatest interest to a general population. Does personalized genetic information really matter for most people? If not, 

why not? If it does matter, why and how does it matter? And how can genetics and bioethics practitioners educate the public (and 

each other) about its meaning and value (or lack thereof)? 


Thursday, May 19


48 



11:00 am - 1:00 pm 

Room: 606-607 

Viral Vectorology from Surface Targeting to Cytoplasmic Restriction 

CHAIR 


SPEAKERS 


Multi-species Based AAV Capsid Evolution Using Various Selection Parameters: New AAV Vectors for Gene Therapy 

We have previously shown that AAV capsid DNA libraries can be used to select for capsids with novel infection/transduction 

properties (Grimm et al., 2008). We constructed new AAV capsid libraries starting with 10 multi-species variant capsid genes. These 

DNAs were randomly digested and re-assembled using PCR, and each unique sequence was cloned into an AAV genome. We 

selected for viruses that were able to efficiently replicate in primary human hepatocytes in vivo or in human pulmonary arterial 

endothelial cells in culture. At each round of selection, the changing population and capsid composition of each chimeric AAV 

sequence was determined. The emergence and biological significance of specific capsid clones will be discussed as well as the 

gene transfer properties of vectors packaged with selected chimeric capsids of interest. 

Glen Barber, PhD 

Intracellular DNA-Sensing Pathways that Trigger Innate Immune Responses 

The innate immune system is critical for the early detection of invading pathogens and for initiating cellular host defence 

countermeasures which includes the production of type I interferon (IFN). While significant progress has been made into determining 

cellular processes underlining the detection of RNA viruses, less is known about how the innate immune system is galvanized to respond 

to DNA based microbes or intracellular plasmid DNA, sensing pathways that can effect gene therapy strategies. Recently, we reported 

that STING (stimulator of interferon genes) is critical for the induction of IFN by non-CpG, intracellular DNA species produced by various 

DNA pathogens and vectors following infection. Murine embryonic fibroblasts (MEFs) lacking STING, as well as antigen presenting cells 

(APCs) such as macrophages and dendritic cells (DC’s) exposed to intracellular B-form DNA, herpes simplex virus 1 (HSV-1) or Listeria 

were unable to produce IFN or other key innate immune genes. STING’s importance in mediating DNA innate immune responses was 

also made evident since CTL–responses induced by plasmid DNA vaccination were reduced in STING deficient animals. In the presence 

of intracellular DNA, STING relocalized with tank-binding kinase 1 (TBK1) from the endoplasmic reticulum (ER) and association with ERmembrane 

associated mitochondria (MAM), to endosome vesicles. Our data indicates that STING is essential for host defense against a 

variety of DNA pathogens and also required for effective innate immune responses that facilitate effective DNA vaccination. 

Greg Towers, PhD 

Restriction of HIV and Retargeting of HIV Integration 

We have sought a role for cyclophilin proteins in the replication of HIV-1. We have shown that several cyclophilins recruit to the 

incoming HIV-1 core and impact on the choice of pathway by which HIV-1 enters the nucleus. The use of different pathways leads 

to integration into different sites in the host cell genome and this in turn influences replication capacity. The interaction between 

HIV-1 capsid and cyclophilins can be manipulated by capsid mutation. Thus capsid mutation can be used to retarget HIV-1 

integration and may be useful in targeting/re-targeting HIV-1 based gene therapy vectors. 


Targeting Lentiviral Vectors with Engineered Measles Virus Glycoproteins 


1:00 pm - 2:30 pm 



MEET-THE-INVESTIGATOR LUNCH SESSION 220 

1:00 pm - 2:30 pm 

Room: 303 

Career Development: Academic vs. Industry 

SPEAKERS 

Seng H. Cheng, PhD 



1:00 pm - 2:30 pm 

Room: 304 

Translational Research 

SPEAKERS 


Joseph Zabner, MD 


1:00 pm - 2:30 pm 

Room: Meet at the Registration Desk by 1:05pm 

Ellison Stem Cell Core Facility Tour 

SPEAKERS 

C. Anthony Blau, MD 

Carol B. Ware, PhD 


2:30 pm - 4:30 pm 

Room: 615-617 

Adenovirus and Other DNA Virus Vectors II: Response to Vectors 

CO-CHAIRS 

Steven Craig Ghivizzani, PhD 




2:30 pm - 4:30 pm 

Room: 611-612 

Chemical and Molecular Conjugates 

CO-CHAIRS 





Thursday, May 19


50 



2:30 pm - 4:30 pm 

Room: 618-620 

Musculo-skeletal Gene & Cell Therapy 

CO-CHAIRS 





2:30 pm - 4:30 pm 

Room: 6A 

Cancer Immunotherapy - Emphasis on Vaccines and Adjuvants 

CO-CHAIRS 


Daniel J. Powell, Jr., PhD 



2:30 pm - 4:30 pm 

Room: 606-607 

Small RNA and Oligonucleotide Based Therapeutics 

CO-CHAIRS 





2:30 pm - 4:30 pm 

Room: 608-609 

Stem Cell Therapies I 

CO-CHAIRS 

Ann Leen, PhD 




2:30 pm - 3:30 pm 

Room: 602-604 


CO-CHAIRS 







3:40 pm - 4:40 pm 

Room: 602-604 

Lung and Respiratory Disease Gene & Cell Therapy 

CO-CHAIRS 




EXHIBIT HALL OPEN & NETWORKING RECEPTION 

4:40 PM - 6:40 PM 

Room: Hall 4B 

POSTER SESSION I 

4:40 PM - 6:40 PM 

Room: Hall 4B 

RNA Virus Vectors I 


AAV Genome & Host Interactions 


Adenovirus and Other DNA Virus Vectors I 



(Abstracts 149-182 and Abstract 914 from Poster Session III; see pages 98-100) 

Genetic and Metabolic Diseases Gene & Cell Therapy I 

(Abstracts 183-193 and Abstract 464 which moved from Poster Session II; see pages 100-101) 

Neurologic & Ophthalmic Gene & Cell Therapy I 

(Abstracts 194-207; Abstract 197 withdrawn; see page 101) 

Infectious Diseases and Vaccines I 


Cancer - Immunotherapy I 




Hematologic and Immunologic Gene & Cell Therapy I 

(Abstracts 250-269 and Abstract 831 from Poster Session III; see pages 104-106) 

Lung and Respiratory Disease Gene & Cell Therapy 


Immunologic Host Responses in Gene & Cell Therapy 


Gene Regulation I 



(Abstracts 310-325; Abstract 320 withdrawn; see pages 108-109) 

Late Abstracts I 



Thursday, May 19


52 

Program Schedule Friday, May 20, 2011 

GEORGE STAMATOYANNOPOULOS LECTURE 300 

8:00 am - 9:15 am 

Room: 6BC 

George Stamatoyannopoulos Lecture 

CHAIR 


SPEAKERS 

Victor J. Dzau, MD 

Paracine Mechanisms of Stem Cell Action in Tissue Repair and Regeneration 

Numerous studies by our group and others have demonstrated that stem cells contribute to tissue repair and regeneration by 

releasing important paracrine factors in a dynamic spatial-temporal manner that can lead to cell survival, angiogenesis, tissue repair 

and remodeling, as well as cellular regeneration. This presentation will provide an overview of the current status of the field as well 

an update on our work regarding the characterization of those factors. 

EXHIBIT HALL COFFEE SOCIAL 

9:15 am - 10:00 am 

Room: Hall 4B 


10:00 am - 12:00 pm 

Room: 6A 

Clinical Trials 

CHAIR 


SPEAKERS 


AAV Gene Therapy for Age Related Macular Degeneration 

The neovascular form of age related macular degeneration (AMD) is the leading cause of blindness of persons over 65 years of age. 

Injectable anti-VEGF agents are approved for AMD treatment and are quite effective resulting in vision stabilization or even vision 

improvement in AMD patients. However, for maximum efficacy these agents must be injected on a monthly basis, thus presenting 

a significant challenge to patients, caregivers and the healthcare system. We are developing an AAV2 mediated AMD gene therapy 

product for sustained expression of an anti-VEGF protein which has completed rodent and non-human primate testing. An update 

on the clinical trial progress of this product candidate will be given. 



Andrew M. Davidoff, MD 

Phase I/II Clinical Trial of AAV8 FIX for Hemophilia B 

We are currently conducting a phase I/II clinical trial of AAV-mediated, liver-targeted transfer of the cDNA for clotting factor IX (FIX) 

in subjects with hemophilia B. Unique aspects of the clinical trial include the use of vector pseudotyped with serotype 8 capsid, a 

self complementary vector genome, codon optimized FIX coding sequence and vector administration via peripheral vein. Thus far, 

six subjects have received vector, two at each of three dose levels (2x10^10 pcr-vp/kg, 6x10^10 pcr-vp/kg and 2x10^11pcr-vp/kg). 

Interim results including safety, efficacy, vector clearance and immune response will be presented. In addition, future plans for the 

continued conduct of this clinical trial, as well as future ones, will be discussed. 

Christof von Kalle, MD PhD 

Gene Therapy for Wiskott Aldrich Syndrome 

Wiskott Aldrich Syndrome is a life-threatening immune-disorder characterized by bleeding secondary to microthrombocytopenia, 

immunodeficiency, autoimmunity, and susceptibility to lymphoma. A clinical gene therapy protocol using transplantation of 

autologous hematopoietic stem cells transduced with a GALV pseudotyped MLV-derived retroviral vector was developed at 

Hannover Medical School. Ten patients treated in this trial between 2006 and 2009 received 3 – 23 x 10e6 genetically modified 

hematopoietic progenitor cells upon partial myeloablative busulfan (8 mg/kg). 9/10 patients had evidence of sustained 

engraftment of WASP-positive hematopoietic progenitor cells. WASP expression was detected in 10% to 60% in myeloid cells, most 

platelets, and increased in T lymphocytes and NK cells to more than 80% after one year. Functional immune reconstitution was 

documented. A clinical benefit was notable in all 9 patients with sustained engraftment: eczema, bleeding diathesis, autoimmune 

phenomena and immunodeficiency resolved. One patient developed a vector associated T ALL, currently undergoing treatment. 

Comprehensive insertion site analysis demonstrated vector integration that targeted multiple genes controlling growth, 

development and immunological responses in a persistently polyclonal hematopoiesis. These data provide the first proof-ofprinciple 

for gene therapy in Wiskott-Aldrich syndrome as a disorder involving autoimmunity and/or platelets. Prospective clinical 

monitoring is required to determine the long-term efficacy and safety profile of this experimental therapy. 

Arthur Levin, PhD 

From Bench to Bedside, the Progress of a Mir122 Inhibitor, Miravirsen 

MicroRNAs are non-coding RNAs that can modulate the translation of multiple mRNAs often whole in biochemical pathways. 

The modulation of mRNAs by miRNAs is often described as fine tuning the expression, and as such miRNAs are interesting targets 

for therapeutic intervention. Using Locked Nucleic Acid modified oligonucleotides (LNAs) it is possible to create high affinity 

miRNA antagonists that bind and sequester specific miRNAs or specific miRNA families. Sequestration of a miRNA in a LNA-miRNA 

heteroduplex effectively inhibits the activity of the miRNA. miR-122 is a hepatic specific miRNA that is known to be a co-factor for the 

accumulation of hepatitis C virus and it is also known to control energy and lipid metabolism. Miravirsen is an 15-mer LNA-modified 

oligonucleotide that binds to and sequesters miR-122. Miravirsen is the first miRNA-targeting drug in clinical trials and the data 

obtained in laboratory studies and in clinical trials supports the concept that miRNAs can be utilized as therapeutic targets. 


10:00 am - 12:00 pm 

Room: 615-617 

Clinical Trials on Stem Cells 

CO-CHAIRS 


Karin M.L. Gaensler, MD 

SPEAKERS 


Neural Stem Cell-Mediated Therapy for High Grade Gliomas 

Neural stem cells (NSCs) display inherent tumor-tropic properties that can be exploited for targeted delivery of anti-cancer 

agents to invasive and metastatic solid tumors. NSCs are not impeded by the BBB and can target brain tumor sites whether 

administered intracranially or intravenously. Significant therapeutic efficacy has been achieved with modified NSCs in preclinical 

models of glioma, melanoma brain metastases, and medulloblastoma. We now present a first-in-human clinical trial using a 


Friday, May 20


54 


v-myc immortalized, clonal human NSC line, modified to express cytosine deaminase, an enzyme that converts the prodrug 

5-Fluorocytosine (5-FC) to the active chemotherapeutic 5-Fluorouracil (5-FU), in patients with recurrent high-grade glioma. 

Jane S. Lebkowski, PhD 

Development of Human Embryonic Stem Cell-Based Therapies for the Treatment of Human Degenerative Diseases 

Human embryonic stem cells have the ability to differentiate into essentially all cell types of the body providing therapeutic 

potential for numerous diseases. The spectrum of hESC-based cell therapy products currently under development span diverse 

applications including: cardiomyocytes for heart failure, islets for diabetes, chondrocytes for chondral defects, dendritic cells for 

the active immunotherapy, endothelial cells for blood vessels, and dopaminergic neurons for Parkinson’s disease. Preclinical testing 

of hESC-based therapeutic products must address the activity, biodistribution, phenotype, proliferation capacity, immunogenicity, 

and toxicological potential of the cells. In addition, developments of controlled processes to manufacture and characterize these 

products are critical for providing a reproducible and reliable therapeutic supply. An update on hESC-based therapies in or nearing 

clinic testing will be provided. 

Nicholas Boulis, MD 

Spinal Cord Surgery for Cellular and Molecular Segmental ALS Therapy 

Current proof of principle data supporting direct spinal cord injection of stem cell and gene therapies for motor neuron protection 

will be reviewed. Human translation of these approaches required the development of techniques and devices to facilitate 

safe and accurate spinal cord injection. The development of these techniques and devices will be reviewed. In 2010, this work 

culminated in the first spinal cord transplantation trial for ALS. Clinical trial design will be discussed as well as an update on 

progress to date. 

Kevin D’Amour, PhD 

Developing an Encapsulated Stem Cell Therapy for Diabetes 

ViaCyte is a preclinical therapeutic company developing an encapsulated cell therapy for the treatment of insulin-dependent 

diabetes. The therapy is based on the differentiation of embryonic stem cells into pancreatic beta cell precursors (Pro-Islet) and 

we have demonstrated that his progenitor based therapeutic approach consistently produces therapeutically relevant levels of 

insulin in response to blood glucose and sustains diabetic animals. ViaCyte has GMP hESC banks and has developed methods for 

large-scale manufacture of hESC cultures and Pro-Islet cell products (capable of 20 Billion Pro-Islet cells in ~4 weeks). In addition, 

ViaCyte is developing a retrievable, non-biodegradable, encapsulation device (Encaptra) that enables implanted Pro-Islet to 

survive and differentiate into functioning islet cells. The Encaptra system is manufactured from FDA compliant implant grade 

materials and is being designed with the goal of eliminating the need for long-term immunosuppressant drugs. 


10:00 am - 12:00 pm 

Room: 611-612 

Cutting Edge Vectors and New Advances in Physical Gene Delivery 

CHAIR 

Shulin Li, PhD 

SPEAKERS 

Adam Bogdanove, PhD 

TAL Effector Nucleases for Genome Editing 

TAL effector nucleases (TALENs) are a new class of engineered, highly targetable protein for genome editing that promise to 

greatly accelerate the pace of discovery and the development of therapeutic approaches to genetic disorders. Fusions of the 

sequence-specific DNA binding domain of transcription activator-like (TAL) effectors from plant pathogenic Xanthomonas spp. 

to the sequence non-specific catalytic domain of the FokI nuclease, TALENs create targeted double strand breaks in DNA in vivo 

that can be exploited for gene disruption, insertion, or replacement. DNA targeting is modular, based on an apparently contextindependent, 

one-to-one association between polymorphic repeats in the TAL effector domain and nucleotides in the target, so 

TALENs can be customized to recognize new targets without the empirical or selection-based protocols required for alternatives 

such as zinc finger nucleases and homing endonucleases. This presentation will review advances in the development and use of 

TALENs for genome editing, including an examination of their potential limitations, as well as the use of TAL effectors in other DNA 

targeting applications. 



Paul A. Grayburn, MD, FACC 

Islet Regeneration in Severe Diabetes by Gene Therapy Targeted to the Pancreas with Ultrasonic Microbubble Destruction 

Ultrasound-targeted microbubble destruction (UTMD) can be used to selectively deliver gene (or drug) therapy to specific 

organs. Gas-filled microbubbles are loaded with plasmid or naked DNA and circulated intravenously. Ultrasound is used to disrupt 

the microbubbles in a specific organ or tissue, thereby resulting in organ-specific delivery. This presentation will discuss the use of 

UTMD to deliver gene therapy to the pancreas of diabetic animals to achieve regeneration of islets and cure of diabetes. 

Dexi Liu, PhD 

12 Years of Hydrodynamic Gene Delivery: How Close are We from Clinical Use? 

The past 12 years have marked significant progress in establishing the concept and methodology of hydrodynamic gene 

delivery as a simple and effective procedure for intravascular gene delivery in rodents. Various applications of this method have 

been reported, including therapeutic gene discovery in vivo; development of optimal plasmid for desirable gene expression; 

identification of therapeutic siRNAs; and establishment of animal models for human viral infection. This talk will focus on recent 

progress toward developing a clinically applicable hydrodynamic procedure for human gene therapy. Recent results from 

experiments designed to assess safety and effectiveness of a computer assisted image-guided hydrodynamic gene delivery 

procedure in pigs, dogs and baboons will be presented. 

Julie Gehl, MD, PhD 

Drug and Gene Delivery to the Brain: Results from a Novel Brain Electroporation Electrode 

Gene electrotransfer is increasingly being used for gene delivery to a number of different tissues, and clinical studies have been 

performed on gene electrotransfer to tumors, skin and muscle. Gene electrotransfer to brain has awaited development of electrode 

technology. We have been performing electroporation for drug and gene delivery in the treatment of cancer patients for over a 

decade. Based on our experience we have developed an electrode for drug and gene delivery to brain tissue and brain tumors, 

which is now ready for clinical use. Preclinical data on an experimental brain tumor model will be presented, as well as a peak into 

the first clinical trial experience. 


10:00 am - 12:00 pm 

Room: 606-607 

Early Virus-Host Interactions 

CHAIR 


SPEAKERS 

Michael Emerman, PhD 

Evolution and Function of Host Defenses against Retroviruses 

We can trace the history some ancient viral infections from “fossils” left behind in primate genomes in the form of defective 

integrated proviruses. However, other ancient viral infections can be inferred from their effects on the evolution of host antiviral 

genes. The genetic conflict of antiviral genes with virally-encoded antagonists of these host defenses viruses results in patterns 

of adaptive evolution of the host genes which can be used to deduce when a given gene was under positive selection, and 

consequently when possible Darwinian selection due to a pathogenic viral challenge acted during primate evolution. In this talk I 

will explore the ideas of restriction factors against retroviruses and the interplay between ancient infection events and modern viral 

infections. These ideas are important in understanding how to optimize viral-mediated gene therapy approaches for humans and 

model systems. 

Grant McFadden, PhD 

The Curious Road from Poxvirus Tropism to Oncolytic Virotherapy 

Poxviruses have been developed as cancer therapy vector platforms in several ways: vaccination strategies targeted against cancer 

cell antigens, delivery vehicles for anti-cancer cytokines or immunotherapeutics, and as direct oncolytic virotherapeutics to target 

cancer cells for elimination. This presentation will summarize the progress in our lab to adapt one specific nonhuman poxvirus, 

myxoma virus, as an oncolytic virotherapeutic against human cancer. Recent preclinical progress in utilizing this virus to treat 

disseminated pancreatic cancer, and as a purging reagent to eliminate contaminating cancer cells from autologous hematopoietic 

stem cell transplants, will be summarized. 


Friday, May 20


56 


Andrea Amalfitano, DO, PhD 

Innate Immune Responses and Gene Transfer 

The innate immune system has evolved to detect low levels of higher order “non-self” molecular structures, as well as DNA or 

RNA molecules present in inappropriate subcellular locations. Therefore, the in vivo use of any gene transfer vector (virus, non 

viral) will result in activation of several arms of the innate immune system. Extracellular pathogen motif detectors in the blood 

stream, such as the complement system, rapidly bind and direct gene transfer vectors to the reticuloendothelial system prior to 

vector interaction with critically important cells of the host. Overwhelming these systems with extremely high levels of a virus or 

liposome will allow for transduction of cells beyond the RES, but not without significant activation of the innate immune system 

as well. Additionally, many cells targeted for gene transduction by vectors maintain a varied repertoire of membrane bound and 

intracellular pathogen detectors, such as the TLRs. In this talk, results gained from the use of Adenovirus vectors in innate immune 

responsive murine and human models will be highlighted to demonstrate the complexity of these responses, as well how gene 

transfer efficacy or safety outcomes can be improved by molecularly targeting elements of the innate immune system. 


Role of Cellular Proteins in Intracellular Trafficking of AAV Vectors 

For nearly three decades, infection by AAV was assumed to be non-specific, given its broad host-range, which transcends the species 

barrier. In 1996, we provided the first evidence that AAV infection is receptor-mediated, which was subsequently identified to be 

heparan sulfate proteoglycan (HSPG) in Dr. Jude Samulski’s laboratory. In 1999, we also identified fibroblast growth factor receptor 1 

(FGFR1) as a cellular co-receptor for AAV, and others subsequently described the identification of at least five additional cellular coreceptors. 

Post-receptor/co-receptor entry of AAV, we characterized a number of cellular proteins that interact with the viral capsid 

and the viral genome that significantly impact intracellular trafficking as well as AAV-mediated transgene expression. Our more recent 

studies, to be presented at the meeting, have yielded insights into the role of additional cellular proteins that play a key role in various 

steps in the life cycle of AAV, which have implications in the optimal use of AAV vectors in gene therapy of human diseases. 


10:00 am - 12:00 pm 

Room: 602-604 

Novel Cellular and Molecular Therapies in the Lung: Branching out for Inspiration 

CO-CHAIRS 



SPEAKERS 

Susan D. Reynolds, PhD 

Repair Fosters Regeneration of the Airway Epithelium 

Identification of a TSC requires analysis of an individual cell and comparison of its proliferation and differentiation capacity with that 

of other cells within a phenotypically homogenous cell population. Although the existence of TSC from tracheobronchial epithelium 

and a specific niche had been postulated, three essential functions of a stem cell (self-renewal, label-retention and multipotential 

differentiation) were not described simultaneously. Therefore the goal of the present study was to identify tracheal TSC and study 

their interaction with the niche. We demonstrate that CD49f bright /Sca1 + /Aldefluor + mouse tracheal basal cells exhibit both stem cell 

characteristics and niche forming function in vitro. This unique basal cell subtype generates three dimensional rimmed clones that 

harbor label-retaining TSC and label-diluting transit amplifying cells (TAC). Homogenous rim clones can be passaged at clonal density 

five times resulting in generation of 40 X 10 6 progeny. Homogenous rim clones are refractory to differentiation signals. However, the 

cycle of proliferation can be broken by interactions with unfractionated tracheal cells. This modified niche is permissive for generation 

of secretory and ciliated cells, the differentiated cell types found in the tracheal epithelium. We conclude that: 1) the tracheal stem cell 

creates the niche; 2) proliferation of TAC is the default state of the niche-stem cell interaction; and 3) interactions with non-niche cells 

generate a modified environment that is permissive for differentiation. 

Andrew A. Wilson, MD 

Manipulation and Tracking of Alveolar Macrophage Gene Expression In Vivo 

The ability to manipulate gene expression in a targeted fashion in vivo has been a longstanding goal for medical researchers and 

practitioners. We have developed lentivirus-based methods to overexpress or downregulate gene expression specifically in alveolar 



macrophages. We have found that alveolar macrophages are long-lived cells, thus establishing them as potential targets for lungfocused 

gene therapy. Through the use of a novel lentiviral reporter vector, we are able to use in vivo imaging technology to track 

knockdown of transcription factor activation in live animals in real time. 


Phase 2 Trial of rAAV1 Gene Therapy for Alpha-1 Antitrypsin Deficiency 

Recombinant adeno-associated virus (rAAV) vectors offer promise for gene therapy of alpha-1 antitrypsin (AAT) deficiency. In 

a previous clinical trial, a rAAV vector expressing human AAT (rAAV1-CB-hAAT), produced using plasmid transfection, was 

administered by intramuscular (IM) injection at a maximum dose of 8.7 x 10 11 vector genomes (vg)/kg and demonstrated AAT 

expression at low levels that was sustained for >1 year. In this clinical trial, the same vector produced using a herpes simplex 

virus complementation system was administered by IM injection at doses of 6.0 x 10 11 , 1.9 x 10 12 and 6.0 x 10 12 vg /kg. Vector 

administration was well tolerated, with only mild local reactions and no serious adverse events. Serum creatine kinase (CK) levels 

were elevated at Day 30 in 5 of 6 subjects in the higher dose groups and were normal at Day 45 and beyond. Expression of 

M-specific AAT in serum was dose-dependent, peaked at Day 30, and persisted at lower levels through Day 90. As expected, all 

subjects developed anti-AAV antibodies and IFN-γ ELISPOT responses to AAV peptides. None of the subjects developed antibodies 

to AAT. One subject in the mid-dose group developed an IFN-γ ELISPOT response to AAT peptides that was not associated 

with any untoward clinical effects. Muscle biopsies at Day 90 showed a varying degree of inflammatory infiltrates and strong 

immunostaining for AAT. These results provide additional evidence of the safety of AAV gene therapy, and indicate that serum 

levels of transgene expression >20 µg/mL can be achieved. However, further improvements in the design or delivery of rAAV-AAT 

vectors will be required to achieve therapeutic target serum AAT concentrations. 

Thomas Petersen, PhD 

Whole Lung Regeneration: Roles of Matrix Cues and Physical Stimuli 

We have recently demonstrated that decellularized lung matrices can serve as the basis for engineering whole lung tissue, and the 

resultant engineered lungs can participate efficiently in gas exchange when implanted in vivo. However, the specific roles of the 

extracellular matrix and of physical forces in directing cell adherence and differentiation in engineered lung tissues will be key to longterm 

success. The application of physiological physical forces and culture conditions have significant impacts on the repopulating 

epithelium and endothelium, including effects on cell adherence, survival, and differentiation state. Additionally, data indicates that 

repopulating epithelial and endothelial cells adhere or differentiate based on specific cues from localized matrix components. 


10:00 am - 12:00 pm 

Room: 608-609 

Viral Vectors for Immunomodulation of Cancer: From Bench to Bed 

CHAIR 


SPEAKERS 

Pedro Lowenstein, MD, PhD 

Stimulation of Anti-Brain Tumor Immune Responses Through Recruitment of Exogenous Dendritic Cells: 

At the Threshold of a Phase I Trial 

The brain is devoid of classical naïve afferent antigen presenting cells. Through intratumoral expression of Flt3L, we have 

reconstituted the efferent antigen presenting immune loop, which is absent from the normal brain. Together with strategies to 

facilitate presentation of tumor antigens, we have achieved a therapeutic approach which is effective in a large variety of tumor 

models. The transition to a Phase I clinical trial will be described during the talk. 


Immunomodulation in Oncolytic Virus Systems 

Virus vectors are frequently used for cancer gene therapy. The functionality of such interventions not only are affected by 

immunological circumstances but also can be enhanced by immunomodilation with the transgene on the vector. Such situations 

will be explained with examples and the design of the future cancer gene therapy modality will be discussed. 


Friday, May 20


58 


Toshiyoshi Fujiwara, MD, PhD 

Telomerase - Specific Oncolytic Adenovirus for Human Cancer Therapy and Diagnostic Imaging 

Telomelysin (OBP-301) is an attenuated oncolytic adenovirus, in which the telomerase promoter drives expression of E1 

genes. A phase I dose-escalation study of intratumoral injection of Telomelysin demonstrated the safety, tolerability, and 

feasibility of the agent for various solid tumors. We also modified the E3 region of Telomelysin to contain green fluorescent 

protein (GFP) gene for monitoring viral replication (TelomeScan, OBP-401). Following intratumoral injection of TelomeScan, 

it causes viral spread into the regional lymphatic area and selectively replicates in neoplastic lesions, resulting in GFP 

expression in metastatic lymph nodes. This technology has the potential to allow surgeons to provide optimal treatment as a 

surgical navigation system. 

Andre Lieber, MD, PhD 

Hematopoietic Stem Cell Based Relaxin Gene Therapy of Breast Cancer 

Extracellular matrix (ECM) in solid tumors affects the effectiveness of therapeutics through blocking of intratumoral diffusion and/ 

or physical masking of target receptors on malignant cells. This includes receptors for therapeutic monoclonal antibodies and 

adenovirus vectors. We tested whether intratumoral expression of the peptide hormone relaxin would result in ECM degradation 

and the improvement of immune therapy. As viral gene delivery into epithelial tumors with extensive tumor ECM is inefficient, 

we used a hematopoietic stem cell (HSC)-based approach to deliver the relaxin gene to the tumor. We show in syngeneic tumor 

models that this approach facilitates pre-existing or transplanted anti-tumor T-cells to control tumor growth. Furthermore, in 

xenograft models with Her2/neu-positive breast cancer cells, HSC-mediated relaxin expression improved the anti-tumor efficacy of 

trastuzumab/Herceptin. 


10:00 am - 12:00 pm 

Room: 618-620 

State-of-the-Art in Tissue Engineering: Implications for Gene Therapy 

CO-CHAIRS 

Daniel R. Salomon, MD 

Tatiana Segura, PhD 

SPEAKERS 

Robert E. Guldberg, PhD 

Promoting Endogenous Bone Regeneration 

Biomaterial scaffolds functionalized to stimulate endogenous repair mechanisms via incorporation of osteogenic cues offer a 

potential alternative to bone grafting for treatment of large bone defects. We first quantified the ability of a self-complimentary 

adeno-associated viral vector encoding for bone morphogenetic protein 2 (scAAV2.5-BMP2) to enhance human stem cell 

osteogenic differentiation in 2D and 3D culture in vitro. Next, we tested the ability of biomaterials mediated delivery of scAAV2.5- 

BMP2 to repair large bone defects in vivo and compared the results to current protein delivery methods used clinically. The results 

showed that biodegradable porous polymer scaffolds coated by thermostable, lyophilized scAAV2.5-BMP2 enhanced osteogenic 

differentiation in vitro and significantly increased bone regeneration in vivo. 

Geoffrey Gurtner, MD 

Biologic Brachytherapy: Ex vivo Transduction of Microvascular Free Flaps for Targeted Gene Therapy 

Gene therapy remains a promising modality for the treatment of local diseases (solid tumors, recalcitrant infection) but has been 

hampered by difficulties in achieving robust and targeted therapeutic production with acceptable systemic exposure and toxicity. 

Microvascular free flaps are routinely performed clinically in the treatment of patients with these conditions. Free flaps require 

the auto-transplantation of composite tissue (skin, muscle, fat) from one anatomic region to another. Since these free flaps are 

detached from the systemic circulation (ex vivo) for a finite period of time, surgeons have a unique opportunity to treat these flaps 

with transfection/transduction protocols that would be unacceptable in vivo because of potential toxicity. Preclinical work suggests 

that this approach holds the potential to provide high level targeted therapeutic production with minimal systemic toxicity. 



Lonnie D. Shea, PhD 

Advancing Islet Transplantation: From Engraftment to the Immune Response 

The promise and progress of islet transplantation for treating type-1 diabetes has been challenged by obstacles to patient 

accessibility and long-term graft function that may be overcome by integrating emerging technologies in gene delivery, 

biomaterials, and immunomodulation. The microenvironment of islets following hepatic infusion and traditional systemic 

immunosuppression stress the vulnerable islets and contribute to limiting success. Locally delivering trophic factors can 

enhance transplantation at extrahepatic sites by promoting islet engraftment, revascularization and long-term function while 

avoiding unintended systemic effects. Cell- and cytokine-based therapies for immune cell recruitment and reprogramming can 

inhibit local and systemic immune system activation that normally attacks transplanted islets. Combined with antigen-specific 

immunotherapies, states of operational tolerance may be achievable, reducing or eliminating the long-term pharmaceutical 

burden. Integration of these technologies to enhance engraftment and combat rejection may produce transformative advances to 

the therapeutic efficacy and availability of islet transplantation. 


12:00 pm - 1:15 pm 


1:15 pm - 3:15 pm 

Room: 6A 

AAV Capsids & Trafficking 

CO-CHAIRS 

Kirsten AK Weigel-Van Aken, MD 




1:15 pm - 3:15 pm 

Room: 606-607 

Genetic and Metabolic Diseases Gene & Cell Therapy II 

CO-CHAIRS 





1:15 pm - 3:15 pm 

Room: 611-612 

Hematologic and Immunologic Gene & Cell Therapy 

CO-CHAIRS 


Eirini P. Papapetrou, MD, PhD 



Friday, May 20


60 



1:15 pm - 3:15 pm 

Room: 608-609 

Cancer Immunotherapy - Emphasis on Adoptive T Cell Transfer 

CO-CHAIRS 

Laurence JN Cooper, MD, PhD 




1:15 pm - 3:15 pm 

Room: 618-620 

Cancer-Oncolytic Viruses 

CO-CHAIRS 





1:15 pm - 3:15 pm 

Room: 615-617 

Stem Cell Therapies II 

CO-CHAIRS 





1:15 pm - 2:15 pm 

Room: 602-604 

Immunologic & Host Responses in Gene & Cell Therapy 

CO-CHAIRS 

Stephen Gottschalk, MD 

Richard A. Morgan, PhD 



2:30 pm - 3:30 pm 

Room: 602-604 

Cell Processing and Vector Production 

CO-CHAIRS 


Lorraine Matheson 




OUTSTANDING ACHIEVEMENT AWARD LECTURE 330 

3:45 pm - 4:30 pm 

Room: 6BC 

Outstanding Achievement Award Lecture 

CHAIR 


SPEAKER 


Cell and Gene Therapy - Putting it Together 

I entered the field of gene therapy more than 20 years ago, led by my previous experience in clinical and translational bone 

marrow transplantation. I appreciated how the stem cells within the harvested marrow would be excellent targets for gene 

transfer, because in principle a single corrected or modified cell could provide lifelong repopulation of the host with modified 

cells and could benefit multiple lineages. So I have been a long-term believer that cellular and gene therapies are a highly 

complementary pairing. In today’s presentation, I will describe how the barriers to broader introduction of gene-modified cells 

into clinical practice are progressively being overcome. Although genetically modified cells are “complex biologicals” or “advanced 

therapeutic medicinal products” and therefore face many practical, regulatory and economic barriers to their application, 

increasing success and (surprisingly) the changing healthcare environment are beginning to show us how we can effectively 

exploit this combination of approaches, thereby validating both the overall concept - and the society’s new name! 

EXHIBIT HALL OPEN & NETWORKING RECEPTION 

4:40 pm - 6:40 pm 

Room: Hall 4B 


Friday, May 20


62 


POSTER SESSION II 

4:40 pm - 6:40 pm 

Room: Hall 4B 

RNA Virus Vectors II 




Adenovirus and Other DNA Virus Vectors II 


DNA Vectorology & Gene Targeting - I 

(Abstracts 422-438 and Abstract 699 which moved from Poster Session III; Abstract 431 withdrawn; see pages 117-118) 

Physical Methods of Delivery I 

(Abstracts 440-450; Abstract 439 Moved to Oral Abstract Session 413; Abstract 448 withdrawn; see pages 118-119) 

Genetic and Metabolic Diseases Gene & Cell Therapy II 

(Abstracts 451-465.5; Abstract 465 withdrawn; see pages 119-120) 

Musculo-skeletal Gene & Cell Therapy I 

(Abstracts 466-483; Abstract 468 moved to Poster Session I; see pages 120-121) 

Infectious Diseases and Vaccines II 


Cancer-Immunotherapy II 


Cancer-Oncolytic Viruses I 


Cancer-Targeted Gene & Cell Therapy II 

(Abstracts 531-541; Abstracts 539 and 540 withdrawn; see pages 124-125) 

Gene Regulation II 


Oligonucleotide & RNAi Therapeutics I 

(Abstracts 553- 570 and Abstract 837 which moved from Poster Session III; Abstract 552 withdrawn; see pages 125-126) 





Late Abstracts II 

(Abstracts 889-910; Abstract 890 withdrwan; see pages 128-129) 

FRIDAY NIGHT PARTY 

7:00 pm - 9:00 pm 

Room: Skybridge (Level Four) 


Program Schedule Saturday, May 21, 2011 

ASGCT BUSINESS MEETING 

7:30 am - 8:00 am 

Room: 618-620 

A light continental breakfast and coffee will be served at 7:15 am. 

OUTSTANDING NEW INVESTIGATOR SYMPOSIUM 400 

8:00 am - 9:45 am 

Room: 6BC 

Outstanding New Investigator Symposium 

CHAIR 


SPEAKERS 


In Vivo Viral Genome and Capsid Biology of Recombinant AAV Vectors 

Recombinant AAV (rAAV) has gained increasing attention as a promising in vivo gene delivery vehicle. To exert its function in 

targeted cells in vivo, rAAV viral coat overcomes various intra- and extra-cellular barriers, and rAAV viral genome undergoes 

processing primarily by DNA repair machinery. However, the underlying molecular and cellular mechanisms in rAAV-mediated in 

vivo gene delivery and transduction have not been clearly understood. We have addressed how rAAV genomes recombine and 

integrate in murine tissues to understand the in vivo viral genome biology, and more recently developed a new high-throughput 

system that integrates next generation sequencing technologies to further understand the complicated in vivo AAV capsid 

biology. Such basic studies on rAAV vectors in the in vivo context will help develop next generation of rAAV vectors, broaden their 

application, and significantly contribute to successful human gene therapy with rAAV vectors. 


AAV-Mediated Gene Therapy for Neuro-Metabolic Diseases and Brain Tumors 

Work in our laboratory centers on devising gene therapy strategies for lysosomal storage diseases and brain tumors. The etiology 

of these diseases is obviously unrelated, but they share a common widespread phenotype. Lysosomal storage diseases with 


Saturday, May 21


64 


neurological involvement usually affect most structures in the brain; the hallmark of glioblastoma multiforme (GBM) cells is 

their remarkable ability to infiltrate normal tissue and migrate long distances away from the main tumor mass leading to tumor 

recurrence. We are using direct infusion of AAV vectors into brain parenchyma to develop new therapies for these diseases. GM1gangliosidosis 

(GM1) and Tay-Sachs disease (TSD) are lysosomal storage diseases caused by deficiencies of acid β-galactosidase 

or β-hexosaminidase A, respectively, resulting in progressive accumulation of gangliosides (GM1 or GM2) in the CNS. These 

diseases are characterized by moderate to severe neurological impairment depending on the age of onset. We have develop a 

strategy of targeting AAV gene delivery to highly interconnected structures in the brain to achieve global distribution of lysosomal 

enzymes throughout the CNS. Based on this principle we developed an AAV-based gene transfer approach targeting 2 sites per 

brain hemisphere to achieve global distribution of lysosomal enzymes throughout the CNS of large animal models with dramatic 

phenotypic improvements and extension in lifespan. For brain tumor therapy we are exploring the concept of using AAV vectors 

to create a zone of resistance to tumor growth by transducing normal cells in the brain to express anti-tumor proteins. We have 

demonstrated the effectiveness of this principle in different brain tumor models. 


Targeting Factor VIII (FVIII) Expression to Platelets for Gene Therapy of Hemophilia A with Inhibitors 

The development of inhibitory antibodies to exogenous factor VIII (FVIII) is considered a severe and important complication of 

FVIII infusion in hemophilia A patients. Gene therapy of hemophilia A with inhibitor is especially challenging because inhibitory 

antibodies in blood circulation may inactivate functional FVIII activity if it is constitutively secrete into plasma. We have developed 

a vector (2bF8) that targets human FVIII expression to platelets under control of the platelet-specific αIIb gene promoter. Using 

this construct, we can correct the murine hemophilia A phenotype even in the presence of high titer inhibitory antibodies in 

a transgenic mouse model. To apply this unique approach to real-life gene therapy, we use lentivirus-mediated bone marrow 

transduction and syngeneic transplantation to introduce platelet-FVIII expression. Our studies have demonstrated that 2bF8 

lentivirus-mediated gene transfer into hematopoietic stem cells can provide sustained improvement of hemostasis in hemophilia A 

mice with pre-existing anti-FVIII immunity, indicating that this platelet-dependent approach may be promising for gene therapy of 

hemophilia A with inhibitors. 


10:15 am - 12:15 pm 

Room: 606-607 

Clinical Gene & Cell Therapy 

CO-CHAIRS 







10:15 am - 12:15 pm 

Room: 615-617 


CO-CHAIRS 





10:15 am - 12:15 pm 

Room: 6A 


CO-CHAIRS 


Selvarangan Ponnazhagan, PhD 



10:15 am - 12:15 pm 

Room: 611-612 

Physical Methods of Delivery 

CO-CHAIRS 


Carol H. Miao, PhD 

(Abstracts 622-629; Abstract 628 withdrawn and Abstract 439 moved from Poster Session II.; see pages 131-132) 


10:15 am - 12:15 pm 

Room: 608-609 

Gene Targeting 

CO-CHAIRS 





10:15 am - 12:15 pm 

Room: 602-604 


CO-CHAIRS 





Saturday, May 21


66 



10:15 am - 12:15 pm 

Room: 618-620 

Neurologic & Ophthalmic Gene & Cell Therapy 

CO-CHAIRS 





12:15 pm - 1:45 pm 


12:15 pm - 1:45 pm 

Room: 211 

Regulated Expression 

SPEAKERS 




12:15 pm - 1:45 pm 

Room: 401 

Targeted Vectors 

SPEAKERS 




1:45 pm - 3:45 pm 

Room: 602-604 

Cardiovascular Cell and Gene Therapy: State-of-the-Art Pre-clinical and Clinical Studies 

CO-CHAIRS 



SPEAKERS 


Role of SDF-1:CXCR4 Axis in Tissue Repair 

Duncan J. Stewart, MD, FRCPC 

Initial Clinical Experience with a Gene-Enhanced Progenitor Cell Therapy for Refractory Pulmonary Hypertension 

Pulmonary artery hypertension (PAH) is a devastating and progressive disease that which there are no truly effective therapies. 

Recent insights suggest that distal arteriolar pruning initiated by endothelial cells (EC) apoptosis plays a major role in the 

pathogenesis of this disease. Therefore we have explored the possibility that vascular repair and regeneration may represent a 

potentially transformative therapy with the potential to restore normal lung vascular structure and function. Preclincial studies 

demonstrated the ability of endothelial progenitor cells (EPC) to prevent monocrotaline-induced PAH and the superiority of 



endothelial NO-synthase (eNOS) gene-enhanced EPCs in the reversal of established disease in the treatment model. A fist in 

human dose-escalation, tolerability study (PHACeT) is now underway and the preliminary results will be presented. 

Brian H. Annex, MD 

Cell and Gene Therapy for Lower Extremity Ischemia 

Peripheral arterial disease (PAD) occurs when atherosclerosis leads to occlusions in a major vascular bed other than the heart 

and the lower extremity is the most frequent site for PAD. Patients with PAD suffer from a range of symptoms that are all due to 

reductions in blood flow to the leg. While attempts to treat PAD by gene transfer have been met with only limited success, there 

are still efforts underway. Cell therapy is currently an area of interest and excitement and we will review the latest information on 

this subject. 

Karen L. Christman, PhD 

Injectable Extracellular Matrix Based Hydrogels for Cardiac Tissue Engineering 

The extracellular matrix (ECM) is nature’s scaffold, and in recent years, researchers have isolated these scaffolds for tissue 

engineering applications by removing all of the cellular components, a process called decellularization. These scaffolds are 

known to promote cell influx, regeneration, and healing in a variety of tissues, and their degradation products have angiogenic, 

chemoattractant, and antimicrobial properties, as well as promote cell migration and proliferation. While these scaffolds retain the 

native ECM structure, they are not amenable to minimally invasive, injectable procedures. We have recently developed a variety 

of injectable ECM derived materials that self-assemble to form porous, nanofibrous scaffolds once injected in vivo or brought to 

physiological temperature. These scaffolds are showing great promise for cardiac tissue engineering. 


1:45 pm - 3:45 pm 

Room: 606-607 

Clinical and Translational Studies for Genetic and Metabolic Diseases 

CO-CHAIRS 


Thierry C. VandenDriessche, PhD 

SPEAKERS 


New Era for Preclinical Studies of Genetic Diseases in Larger Animal Models: The Cystic Fibrosis Example 

Improved gene targeting methodologies in somatic cells and single cell embryos have opened the door to rapidly generate larger 

animal models of genetic disease. Gene targeting with recombinant adeno-associated virus and zinc finger nuclease has been 

employed to generate non-rodent disease models. The field of cystic fibrosis has been the recent beneficiary of this technology 

with the creation of new cystic fibrosis models in the pig and ferret. These models are now helping to dissect difficult questions 

about disease pathogenesis, while also serving as a platform for the preclinical development of gene and cell therapies. 

Dwight Koeberl, MD, PhD 

Rescue Administration of DNA Viral Vectors in Canine Glycogen Storage Disease Type Ia 

The focus of our research has been the development of new therapy for inherited disorders of metabolism, especially glycogen 

storage disease (GSD) Ia. Glucose-6-phosphatase (G6Pase) deficiency in GSD-Ia affects primarily liver and kidney. We have 

developed gene therapy with adeno-associated virus (AAV) vectors and helper-dependent adenovirus (HDAd) vectors. G6Paseknockout 

mice and GSD-Ia dogs provided models for the biochemical abnormalities of GSD-Ia, although early mortality 

complicates research with the murine and canine models of GSD-Ia. The biochemical abnormalities in GSD-Ia provided 

robust endpoints for demonstrating efficacy following vector administration, including the correction of hypoglycemia and 

hyperlipidemia, lactic aciduria, G6Pase deficiency, and glycogen accumulations in the liver and kidney. We demonstrated that both 

an AAV8-pseudotyped AAV vector encoding human G6Pase and an HDAd vector encoding canine G6Pase prolonged the survival 

and reversed the biochemical abnormalities in mice and dogs with GSD-Ia for > 1 year. More recently, the efficacy of AAV7 and 

AAV9 vectors have been evaluated in mice and dogs with GSD-Ia with regard to the prevention of hypoglycemia during prolonged 

fasting, and the prevention of long-term complications of GSD-Ia including renal dysfunction. 


Saturday, May 21


68 


Fatima Bosch, PhD 

Gene Therapy for Diabetes: Moving to Clinic? 

Diabetes mellitus is a chronic disease with severe secondary complications for which there is no cure. To counteract diabetic 

hyperglycemia by increasing glucose uptake, we generated in skeletal muscle a “glucose sensor” as a result of the co-expression of 

insulin and glucokinase via AAV1 vectors. This is a safe approach that allows long-term reversal of diabetic alterations and survival 

(>3 years) in Beagle diabetic dogs demonstrating the potential of this therapy. 

Marina Cavazzana-Calvo, MD, PhD 

Gene Therapy for Haematopoietic Diseases : New Data on Ongoing Clinical Trials 


1:45 pm - 3:45 pm 

Room: 6A 

Gene & Cell Therapy Around the Globe: A Showcase of Asia 

CHAIR 


SPEAKERS 

Hideyoshi Harashima, PhD 

Controlled Intracellular Trafficking of Non-viral Vectors 

It is widely known that viral vectors are much more efficient than non-viral vectors, however, little is known about which process 

is responsible for this difference. We addressed this question by developing a quantitative intracellular imaging method for pDNA 

and compared efficiency between viral and non-viral vectors. As a result, intranuclear disposition such as transcriptional and 

translational processes can be rate-limiting processes for non-viral vectors. We have developed original non-viral vector named as 

Multifunctional Envelope-type Nano Device (MEND) and optimized MEND to overcome the rate-limiting step to achieve antigen 

presentation in primary dendritic cells as well as to induce antitumor effects. These results indicate that the optimized MEND can 

be a breakthrough technology for DNA vaccine. 

Masayuki Yamato, PhD 

Current Status of Clinical Applications of Cell Sheet Engineering for Regenerative Medicine 

We will show the pipelines and current status of clinical applications of regenerative medicine using cell sheet engineering. Skin, 

cornea, heart, and esophagus have been treated with transplantable cell sheets fabricated on temperature-responsive culture 

surfaces in human clinical settings. 

Duanqing Pei, PhD 

Improving Reprogramming Through Culture Changes 

We have established a robust platform for the generation of patient specific pluripotent stem cells by defined factors. A bank 

of those iPSCs have been created in our institute. We are performing gene corrections for the genetic mutations. We will try to 

establish protocols to differentiate those iPSCs for therapeutical applications. 

Wenlin Huang, PhD 

A Multicenter, Open-label, Randomized Phase II Trial of Adenovirus-mediated Endostatin Gene Therapy in Combination 

with Paclitaxel and Cisplatin Chemotherapy in Advanced Head and Neck Carcinoma: Preliminary Results 

Background: E10A is an adenovirus containing human endostatin gene (Ad-rhE). The phase I clinical trial of E10A revealed that 

weekly intratumoral injection of up to 1 × 10 12 VP of E10A to patients with solid tumor is a feasible and well-tolerated procedure 

that exerts mild antitumor effects. In this trial, we aimed to evaluate the safety and efficacy of E10A combined with paclitaxel/ 

cisplatin chemotherapy in advanced head and neck carcinoma (ClinicalTrials.gov identifier: NCT00634595). 

Methods: Patients treated with chemotherapy alone were given paclitaxel (160mg/m 2 on d1) and cisplatin (25mg/m2 on d1, d2 

and d3) every 21 days. Patients in combination group received two intratumral injections of E10A on days 1 and 8, combined with 

paclitaxel (160mg/m 2 on d3) and cisplatin (25mg/m2 on d3, d4 and d5), and then every 21 days as long as no PD or untolerable 

toxicity occurred. The primary efficacy criterion was response rate (CR/PR) determined in cycle 2 to cycle 4. Patients were assessed 

for toxicity and viral shedding, and antitumor response was evaluated by imaging techniques and tumor biopsy. 



Results: As of November 2010, evaluable population included 120 subjects. In combination group, 1/59 had CR and 25/59 had PR. 

For patients received chemotherapy alone, 0/61 had CR and 14/61 had PR. The most effects. frequent adverse events associated 

with E10A were fever and local reaction of injection site, primarily grades 1 and 2. 

Conclusions: Intratumoral injection of E10A is feasible and well tolerated and shows encouraging antitumor effects. 


1:45 pm - 3:45 pm 

Room: 611-612 

Genetic Vaccines 

CHAIR 


SPEAKERS 

Lawrence Corey, MD 

HIV Vaccine Development 

Efficacy trials of preventive HIV vaccines continue to provide surprising yet critical insights for future HIV vaccines. Vaccine regimens 

with easily measurable immune responses of high magnitude and frequency, such as the Merck Ad5 gag-pol-nef vaccine, 

provided little protection from infection or long term immune control. However, a recent vaccine regimen of a canarypox gp 120 

combination vaccine provided nearly 60% efficacy in the first year after vaccination and 30% efficacy overall. This regimen elicited 

poor CD8+ and mediocre CD4+ T cell responses in phase I and II evaluations. Recent analyses of the longer term follow up of the 

Step trial indicate an interaction between receipt of vaccine and lack of circumcision as well as Ad5 seropositivity. The mechanisms 

of these effects are unclear. Similarly, while NHP models of acquisition are being developed, they are not validated with regards 

to their predictive efficacy. The above data all indicate that our assays and our current animal models to measure immunogenicity 

are poor predictors of HIV vaccine efficacy in a human population. The pace of HIV vaccine efficacy trials has been slow (currently 

one trial every 5 to 7 years). If we are to achieve a globally effective vaccine, we need to develop a system to conduct, monitor and 

analyze efficacy trials in a more efficient and expedient manner, linking laboratory and clinical services more effectively. Adaptive 

trial designs offer a major advantage over fixed “traditional” models in weeding out ineffective vaccines and providing initial reads 

on potentially effective vaccine regimens. The use of adaptive designs will be discussed in the context of a more rapid and efficient 

global clinical trials program. 


T Cells and TCR-Like Antibodies to Treat Leukemia 

The potent T cell-mediated graft-versus-leukemia (GVL) effect observed after allogeneic stem cell transplantation contributes 

to improved relapse-free survival for patients with myeloid leukemia. If donor T cells that mediate GVL could be separated from 

T cells that mediate graft-versus-host disease (GVHD) based on antigen specificity, then enrichment of GVL T cells in the donor 

allograft could be devised that might increase GVL and reduce GVHD. Examples of acknowledged GVL T cells target minor 

histocompatibility antigens (e.g. HA-1) and self-antigens (e.g. PR1, WT1) that are expressed in hematopoietic tissues. A limitation to 

selecting PR1-specific cytotoxic T lymphocytes (PR1-CTL) to mediate GVL is their low precursor frequency and relative low avidity 

T cell receptors (TCRs) compared to TCRs specific for non-self peptides. 8F4, a TCR-like anti-PR1/HLA-A2 monoclonal antibody that 

has 3-log higher affinity for PR1/HLA-A2 compared to PR1-TCR, mediates CDC against primary AML and leukemia stem cells (LCSs) 

and preferentially inhibits AML progenitors. This suggests that 8F4 might be useful in the treatment of leukemia. The biological 

basis of treatment strategies with PR1-CTL and 8F4 will be discussed. 

Philip R. Johnson, MD 

Removing the Roadblock to an HIV Vaccine 

The holy grail of HIV vaccine development is an immunogen that elicits antibodies which broadly neutralize field strains of the 

virus. While tremendous insights have been gained into the structure and function of the HIV envelope glycoprotein, precious 

little progress has been made in designing such immunogens. In fact, it remains formally possible that with current technologies, 

engagement of the adaptive immune system will not lead to an effective HIV vaccine. The mechanisms behind this immune 

evasion will be discussed, along with potential ways around this formidable roadblock. 


Saturday, May 21


70 


Richard Roden, PhD 

Next Generation HPV Vaccines 

Persistent infection with oncogenic human papillomavirus (HPV) is a necessary but insufficient cause of virtually all cervical cancers. 

Thus cervical cancer is entirely preventable through vaccination. However, cervical cancer remains the third most common cause 

of cancer death among women, and reducing this will require broader access to HPV vaccines, especially in the developing world 

where the implementation of secondary screening has met with limited success. We are developing vaccines targeting the minor 

capsid protein L2 to induce protective immunity, as well as therapeutic immune responses to the viral oncoproteins E6 and E7. 

Genetic vaccination shows promise as a low cost approach to deliver such second generation HPV vaccines. 


1:45 pm - 3:45 pm 

Room: 615-617 

Late Stage Industry Clinical Trials 

CO-CHAIRS 

Estuardo Aguilar-Cordova, PhD 

Gabor M. Rubanyi, MD, PhD 

SPEAKERS 

Laura K. Aguilar, MD, PhD 

A Randomized Controlled Trial of ProstAtak as Adjuvant to Up-front Radiation Therapy for Localized Prostate Cancer 

Prostate cancer is the second leading cause of cancer death in men in the US. More than 50,000 men suffer from prostate cancer 

recurrence each year for which no curative therapy exists. ProstAtak is a cytotoxic immunotherapy agent composed of an 

adenoviral vector expressing the Herpes thymidine kinase gene (AdV-tk) injected into the tumor followed by oral administration of 

valacyclovir, an anti-herpetic prodrug. ProstAtak works synergistically with radiation to kill tumor cells as well as stimulate the invivo 

formation of a tumor-specific vaccine to combat micrometastases and recurrence from residual disease. Safety and potential 

efficacy have been demonstrated in Phase 1 and 2 trials with more than 250 patient doses delivered to more than 100 patients 

with prostate cancer. A completely blinded, randomized, placebo controlled trial will definitively evaluate the efficacy of ProstAtak 

in combination with standard external beam radiation therapy in up-front prostate cancer. 

Marnix Bosch, PhD, MBA 

Autologous Dendritic Cells for Glioblastoma 

DCVax-Brain is an autologous cell therapy product for patients with malignant glioma, that has shown significant and meaningful 

clinical benefit in early trials. Northwest Biotherapeutics has designed and initiated a multi-center, placebo controlled double 

blind Phase II trial to test the efficacy and safety of this product. The trial was initiated in 13 sites around the US but enrollment was 

temporarily put on hold due to economic circumstances. At this point the company is resuming enrollment. Further details of trial 

design and the rationale behind it will be presented, as well as an update on clinical data gathered to date. 

Richard S. Geary, PhD 

Mipomersen, an Antisense Oligonucleotide Inhibiting apoB Synthesis, for Familial Hypercholesterolemia 

Isis and Genzyme have successfully completed four Phase 3 studies examining the safety and efficacy of the antisense, apoB 

synthesis inhibitor, mipomersen, in patients whose severe hypercholesterolemia was not adequately controlled on an existing 

regimen of maximally tolerated lipid-lowering therapy. In all of these studies, mipomersen significantly reduced all atherogenic 

lipids including LDL-C, apoB and Lp(a), and had no effect on HDL. The most common adverse event was local injection site 

reactions. Liver enzymes (ALT) were elevated ≥3X ULN for at least 7 days in 8% of mipomersen-treated patients. A detailed 

summary of the safety and efficacy profile for the Phase 3 mipomersen program will be presented. Overall, the data support the 

potential utility of mipomersen as a pharmacologic option to provide additional LDL-C lowering in hypercholesterolemic patients 

not adequately controlled on existing lipid-lowering medications. 



Seppo Ylä-Herttuala, MD, PhD, FESC 

Ad5-VEGF-D for Graft Stenosis 

Vascular access stenosis is a significant problem in dialysis patients. Local gene transfer could be used for the treatment 

of the stenosis at the vascular access site. Safety and efficacy information currently available about the use of Ad-VEGF-D 

vasculoprotective gene transfer for this condition will be described. 


1:45 pm - 3:45 pm 

Room: 608-609 

New Therapeutic Strategies for Neuro-Ophthalmic Diseases 

CHAIR 

Maria G. Castro, PhD 

SPEAKERS 

Christian L. Lorson, PhD 

RNA-based Strategies for Increasing SMN Production in Spinal Muscular Atrophy: Trans-splicing 

Nucleic acid-based therapeutics are an expanding area of investigation and Spinal Muscular Atrophy (SMA) is well suited for a 

variety of these applications. While loss of SMN1 results in SMA, the existence of a nearly identical, but alternatively spliced SMN2 

gene, has made it possible to specifically target SMN2 for a variety of therapeutic strategies that are designed to redirect the 

SMN2 alternative splicing event. Our lab utilizes several strategies to modulate SMN2 pre-mRNA splicing, including trans-splicing, 

antisense oligonucleotides, and bifunctional RNAs. The molecular genetics of SMA and an analysis of nucleic acid-based strategies 

from the test tube to animal models will be discussed. 

Thomas A. Reh, PhD 

The Use of Embryonic Stem Cells in the Treatment of Retinal Degenerations 

We are developing methods for the use of human embryonic stem cells in the repair of retinal degenerations. Using what we 

learned from studying retinal stem/progenitors in vitro over many years, we have developed a technique for directing hES cells 

to the retinal progenitor cell fate (Lamba et al, 2006; P.N.A.S.; 2009, Cell Stem Cell; 2010 PlosOne) and expanding these cells in vitro. 

We now have the capacity to generate large numbers of human retinal progenitors and retinal neurons in vitro and we are 

investigating their ability to replace lost photoreceptors or ganglion cells in mouse models of macular degeneration or glaucoma. 

Botond Roska, PhD 

Targeting Microbial Light Sensors to Retinal Cell Types to Restore Visual Function in Retinitis Pigmentosa 

Retinitis pigmentosa is a hereditary eye disease that affects photoreceptors and leads to blindness. The discovery of a microbial 

light-gated channel and the subsequent development of similar “optogenetic” sensors opened the door for creating artificial 

photoreceptors in the remaining retinal circuits of retinitis pigmentosa retinas via gene therapy. I will show how we combine the 

understanding of retinal cell types, circuits and computations with the ability to equip cell types with optogenetic sensors in order 

to restore visual activity in animal models of retinitis pigmentosa. I then discuss the first translational steps towards therapy. 


4:15 pm - 6:15 pm 

Room: 611-612 

Chemical Gene & Cell Therapy 

CHAIR 


SPEAKERS 


Clinical Development of Plasmid DNA-based Vaccines for Treatment of Cancer and Infectious Disease 


Saturday, May 21


72 


Roger C. Adami, Ph.D. 

Highly Potent DiAlkylated Amino-Acid (DiLA2) Based Formulations for Systemic Liver Delivery 

Highly effective and well tolerated systemic delivery systems remains one of the main hurdles to establishing RNA-based 

therapeutics. Toward this objective, we developed an innovative dialkylated amino acid-based (DiLA2) delivery system that 

provides both efficient hepatocellular uptake and endosomal escape. The resulting particles were between 60 to 80 nm and had 

> 90% of the siRNA encapsulated. Using these particles we obtained an ED50 of 30 µg/kg in mice delivering a Factor VII UsiRNA. 

Complement activation assays with these particles demonstrated C3a levels remain below the buffer treated baseline, suggesting 

minimal to no potential for alternative complement pathway activation. These new DiLA2 systems provide a basis for design and 

development of robust, well tolerated RNA and oligonucleotide delivery systems. 


The Importins of DNA Nuclear Localization 

Entry of plasmids into the nucleus is a required step in all DNA-based transfections and has been seen as one of the greatest 

barriers to effective gene transfer. Our studies over the years have focused on elucidating the mechanisms of plasmid nuclear 

import in non-dividing cells, a key cell target for gene therapy. I will discuss the roles of transcription factors and other proteins in 

the nuclear localization of plasmids, both using in vitro cell culture systems and animal models. 

Patrick S. Stayton, PhD 

pH-Responsive Carriers for Nucleic Acid Delivery 

The long-term objective of our research is to develop new drug delivery systems for macromolecular drugs that must reach 

intracellular targets for efficacy. Biotherapeutics such as siRNA have significant therapeutic potential, but effectively formulating 

and delivering them remains a widely recognized challenge. We have been developing synthetic polymeric carriers that mimic 

the highly efficient intracellular delivery systems found in pathogenic viruses and organisms. Their most important property ties 

together the sensing of pH changes to membrane destabilizing activity, and the carriers thus possess a hidden functionality that 

is expressed in the endosomal compartment to increase cytosolic delivery of macromolecules. The carriers are applicable to a 

wide range of biotherapeutics, and might open up new families of peptide, antibody or nucleic acid drug candidates that attack 

previously inaccessible intracellular targets 


4:15 pm - 6:15 pm 

Room: 6A 

Emerging Hematopoietic Clinical Studies: Challenges and Advances 

CHAIR 


SPEAKERS 


HSC Gene Therapy for Metachromatic Leukodystrophy 

Metachromatic Leukodystrophy (MLD) is a demyelinating lysosomal storage disorder due to deficiency of arylsulfatase A (ARSA) 

lacking effective therapies. According to relevant preclinical data, a Phase I/II clinical trial of hematopoietic stem cell (HSC) gene 

therapy employing lentiviral vectors (LVs) was recently approved for the treatment of MLD and the first patient was treated in our 

Institute in May 2010. Upon administration of a myeloablative dose of busulfan, the patient received autologous BM HSC freshly 

and efficiently transduced with ARSA-encoding LVs. No serious adverse events were reported in the peri- and post-transplant 

phase; a sustained engraftment of the transduced cells and a sustained, above-normal ARSA activity were observed in all blood 

lineages and in BM CD34+ cells up to 6 months follow up. These marking levels far exceed those reported in previous trials using 

gamma-retroviral vectors or LV and, if maintained long-term, would suggest a substantial gain in gene marking efficacy. Thus far, 

the follow up of this patient demonstrates the short-term safety and feasibility of the procedure, but only long-term evaluation will 

establish its safety and efficacy. 




Beta-globin Gene Transfer for the Treatment of Beta-Thalassemia 

The beta-thalassemias are inherited anemias caused by the insufficient production of the beta-chain of hemoglobin. The 

transplantation of autologous CD34+ hematopoietic stem cells genetically modified with recombinant lentiviral vectors encoding 

the human beta-globin gene represents a potential curative therapy for patients lacking an HLA-matched donor. We have shown 

in murine models that beta-thalassemia can be cured upon the transduction of bone marrow cells with optimized TNS9-derived 

lentiviral vectors. Based on these preliminary data, we have conducted a pilot trial in patients with β- thalassemia major to 

primarily investigate the feasibility and safety of peripheral blood hematopoietic progenitor cell (HPC) mobilization with G-CSF and 

determine the yield of mobilized CD34+ HPCs. A secondary objective was to determine whether the collected HPCs are amenable 

to effective transduction with the clinical TNS9.3.55 lentiviral vector that has been manufactured for the planned therapeutic trial. 

Our studies demonstrate that high-level beta-globin transgene expression is maintained in erythroid cells derived from thalassemic 

CD34+ cells. Update will be given on the trials, the yield of CD34+ HPCs, the efficiency of transduction and the level of globin 

expression in patient cells. 


New Approaches to Genetic Correction in Fanconi Anemia 

Previous attempts at genetic correction in Fanconi anemia patients have been unsuccessful, largely due to a reduced numbers of 

hematopoietic stem cell (HSC) targets and the loss of HSCs during in vitro manipulations required for gene transfer. This session will 

review new approaches to address these issues: i) the application of new vector systems that require less in vitro manipulations, 

such as lentivirus vectors, allowing very short ex vivo culture periods; and ii) the development of somatic cell reprogramming that 

allows the generation of unlimited numbers of stem cell targets. These reprogrammed stem cells called induced pluripotent stem 

(iPS) cells can be differentiated into hematopoietic progenitor cells and have the added advantages of unlimited expansion and 

clonability which could facilitate full molecular characterization of genetically corrected cellular products. 


Lentiviral Gene Transfer for Beta-Thalassemia 


4:15 pm - 6:15 pm 

Room: 618-620 

Advancing Genes and Cells into the Clinic - Delivery on Target for CNS Disorders 

CO-CHAIRS 

Thomas Miller, PhD 


SPEAKERS 


Importance of Precise Vector Delivery and Axonal Transport in Gene Therapy Trials for Parkinson’s Disease 

Optimal viral vector delivery into the brain is challenging and brain distribution of viral vectors is uncertain. To address this issue we 

developed viral vector delivery system that permits direct MRI monitoring of vector distribution within the brain in real-time. This 

significant advance allows for the first time to adjust parameters of vector infusion while delivering gene therapy, giving surgeon 

full control over gene transfer technology. Description and performance of this now FDA approved system for viral vector delivery 

to the brain will be presented. 

Eva L. Feldman, MD, PhD 

Intraspinal Stem Cell Transplantation for Amyotrophic Lateral Sclerosis 

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that lead to the specific loss of motor neurons. 

Recently stem cell technologies have been developed for the investigation and treatment of neurodegenerative diseases. I 

will discuss the different stem cells currently being studied for mechanistic discovery and therapeutic development, including 

embryonic, adult and induced pluripotent stem cells. I will also present supporting evidence for the utilization of stem cell 

technology in the treatment of ALS, and describe key issues that must be considered for the transition of stem cell therapies for 

MN diseases from bench to bedside. Finally, I will discuss the first-in-human Phase I trial currently underway examining the safety 


Saturday, May 21


74 


and feasibility of intraspinal stem cell injections in ALS patients as a foundation for translating stem cell therapies for various 

neurological diseases. 

Wilson W. Bryan, MD 

Efficient Drug Development 

The objective of drug development is to deliver safe and effective products to the public. However, development of a product 

from the point of conception through FDA marketing approval requires substantial expenditures of time and money. Sponsors 

can decrease the time and expense by planning ahead for subsequent steps in drug development. Such planning should be a 

collaboration that includes scientists, clinicians, and regulators. This presentation will describe the drug development process, 

focusing on opportunities for sponsor-regulator interactions that can facilitate efficient drug development. 

Steven Piantadosi, MD, PhD 

Impact of Therapy Delivery on Clinical Trial Design 

Panel Discussion 


4:15 pm - 6:15 pm 

Room: 606-607 

Viral Vectors for Gene Targeting and Homologous Recombination in Gene Therapy 

CO-CHAIRS 



SPEAKERS 


Sustainable Gene Transfer and Gene Correction in Stem Cells 

Engineered Zinc Finger Nucleases (ZFNs) are powerful new tools for gene targeting. We have optimized the application of ZFNmediated 

gene editing to several cell types, including human primary lymphocytes, fibroblasts, neural stem cells and induced 

Pluripotent Stem cells (iPSC), and demonstrated the feasibility, efficiency and specificity of gene disruption and site-specific 

integration. We studied the transcriptional and epigenetic impact of different transgene expression cassettes targeted into 

different genomic loci and tailored locus choice and cassette design to achieve robust and uniform transgene expression without 

inducing detectable transcriptional perturbation of the targeted locus and its flanking genes. These studies provide a framework 

for “sustainable” gene transfer that can be exploited in novel experimental paradigms and safer therapeutic applications. We have 

combined gene correction with strategies for safe genetic reprogramming of patient-derived fibroblasts to iPSC, in order to provide 

an alternative and potentially unlimited source of patient-derived, gene-corrected, reprogramming factor free stem cells. These 

iPSC represent invaluable tools to explore methods for inducing their differentiation into hematopoietic cell types and design new 

cell replacement approaches. 

David J. Rawlings, MD 

Modeling Homing Endonuclease Gene Targeting in Primary Cells 

Rare cutting homing endonucleases (HE) represent a promising technology for site-specific genome engineering. However, successful 

application of this technology requires both improved methods for determining the variables that facilitate nuclease-induced gene 

repair and application of this knowledge to use in primary cells populations. To address these goals we will present data describing: 1) 

a novel genome engineering reporter system, that supports rapid flow cytometry analysis of repair pathway choice at individual DNA 

breaks: and 2) progress in applying viral gene modification strategies in a primary cell models of immune deficiency disease. 

Toni Cathomen, PhD 

Exploring and Exploiting Designer Nucleases for Targeted Genome Editing 

Designer nucleases, such as zinc-finger nucleases (ZFNs), are a powerful tool to edit the genome of complex organisms at will. 

As a consequence, designer nucleases have developed into a major playmaker in the genome engineering field and have been 

employed to trigger the targeted editing of genomes at over 50 different gene loci in more than 10 organisms, including human 

stem cells. In my talk, I will summarize the technological innovations that have successfully catapulted ZFNs into the gene therapy 



arena and provide an overview of parameters that determine ZFN activity and ZFN-associated toxicity, both key qualities in any 

therapeutic application involving designer nucleases. As a final point, I will present data that introduce TALe-based nucleases as a 

valuable alternative to ZFNs. 

David W. Russell, MD, PhD 

Gene Targeting with Adeno-Associated Virus Vectors 

AAV vectors efficiently recombine with homologous chromosomal sequences in mammalian cells. Up to 1% of the entire cell 

population exposed to vector particles undergoes gene targeting under optimal conditions. Insertions, deletions and substitutions 

can all be introduced with high fidelity. The technique works well in many cell types, including transformed cell lines, stem cells, 

and even in vivo in murine hepatocytes. In human pluripotent stem cells we have used AAV vectors to target disease-causing 

genes and manipulate chromosomes. 


4:15 pm - 6:15 pm 

Room: 608-609 

Viral Vectors for Immunomodulation of Cancer: From Bed to Bench 

CHAIR 

Laurence JN Cooper, MD, PhD 

SPEAKERS 

Howard L. Kaufman, MD 

Oncolytic Herpes Simplex Virus-1 Encoding GM-CSF for the Treatment of Malignant Melanoma 

Oncovex GM-CSF is an oncolytic herpes simplex virus-1 (HSV-1) in which the ICP 34.5 and ICP47 genes have been deleted and human 

GM-CSF has been inserted. The vector demonstrated therapeutic activity and an acceptable safety profile in a multi-institutional 

Phase II clinical trial. Treatment was associated with local and systemic melanoma-specific CD8+ T cell responses and decreases in 

CD4+CD25+FoxP3+ regulatory T cells and myeloid-derived suppressor cells. An international prospective randomized Phase III clinical 

trial is being conducted. The background rationale, study design, current status and future plans for Oncovex GM-CSF will be discussed. 

Brian Lichty, PhD 

Boosting Anti-tumour Immunity with Oncolytic Vaccine Vectors 

Replicating viral vectors are attractive candidate cancer therapeutics as they can directly mediate tumour destruction via viral 

oncolysis while inducing anti-tumour immunity. These two means of tumour destruction work together to mediate optimal 

therapeutic impact and a reduction in either can reduce efficacy. It is however challenging to develop anti-tumour immune 

responses with replicating viral vectors as these are highly immunogenic and anti-viral immune responses will dominate. We have 

shown that oncolytic rhabdoviral vaccine vectors are very potent boosters of tumour vaccines able to generate massive antitumour 

immune responses in tumour-bearing hosts. The mechanisms underlying these effects and additional means to further 

enhance the effects will be presented. 


Oncolytic Virotherapy and the Immune System: Montague and Capulet or Yin and Yang? 

The efficacy of oncolytic virotherapy for cancer is inextricably linked to the interaction between the virus, the tumor cells and 

the immune system. Immune reactivity to the virus will clearly hinder anti tumor efficacy in as far as it inhibits delivery (through 

neutralising antibody) as well as intra-tumral spread and replication (through the activity of both innate effectors as well as 

anti-viral adpative T cell responses). Conversely, innate and adaptive effectors to the virus can contribute significantly to tumor 

clearance, can lead to the generation of adaptive responses directed against tumor cells and can even enhance systemic delivery 

of viruses by protecting them from neutralization. Data will be presented showing how the tension between oncolytic virotherapy 

and the immune system can be reconciled to generate more effective anti tumor therapies. 

Akseli Hemminki, MD, PhD 

Personalized Cancer Therapy with Oncolytic Adenoviruses 

The attractiveness of personalized medicine with oncolytic adenoviruses has been recognized by EU legislators and patient-bypatient 

treatments are regulated by the Advanced Therapies directive (EU 1394/2007), which has allowed us to treat more than 240 

patients with 10 different viruses in an Advanced Therapy Access Program (also known as “hospital exemption” or “named patient 


Saturday, May 21


76 


basis”). The optimal virus capsid, tumor specific promoter, arming device and virus sensitizers (temozolomide, 3 different schedules 

of cyclophosphamide) are selected based on preclinical and clinical data, taking into account the nature of the clinical problem in 

each patient, while switching the viral capsid has been utilized to enhance systemic delivery. Injections have been performed in 

ultrasound, visual or CT guidance, intratumorally, intracavitary and/or intravenously on an individual basis. Both archival and fresh 

pretreatment tumor samples have been studied by microarray, transduction, cell killing and immunohistochemistry for selecting 

the optimal virus and for prediction of efficacy. Safety, efficacy, biological, virological and immunological data will be reported. 

POSTER HALL SOCIAL 

6:15 pm - 8:15 pm 

Room: Hall 4B 

POSTER SESSION III 

6:15 pm - 8:15 pm 

Room: Hall 4B 

AAV Experimental Therapeutics 


Adenovirus and Other DNA Virus Vectors III 


DNA Vectorology & Gene Targeting - II 

(Abstracts 686-700; Abstract 699 moved to Poster Session II; see page 136) 

Physical Methods of Delivery II 


Genetic and Metabolic Diseases Gene & Cell Therapy III 




Neurologic & Ophthalmic Gene & Cell Therapy II 


Musculo-skeletal Gene & Cell Therapy II 


Cancer-Immunotherapy III 


Cancer-Oncolytic Viruses II 


Cancer-Targeted Gene & Cell Therapy III 


Hematologic and Immunologic Gene & Cell Therapy II 

(Abstracts 820-833; Abstract 831 moved to Poster Session I; see page 145) 

Oligonucleotide & RNAi Therapeutics II 

(Abstracts 834-851; Abstract 837 moved to Poster Session II; see pages 145-147) 

Stem Cell Therapies III 


Late Abstract III 


ANNUAL MEETING CONCLUDES 


Exhibit Hall Floor Plan 

S 

4 1 2 

F 

EXIT 

GATE 7 

WOMEN MEN 

WOMEN 

F 

4C-2 

4C-1 

FE 

FHC 

CWF 

EXIT 

MEN 

FHC 

D 

FE 

FHC 

GATE 6 

D 

18' VERTICAL CLEARANCE 

THIS AREA 

FE 

FHC 

F 

FHC 

FE 

CWF 

ESCALATORS 

FLOORS 4 & 6 

ONLY 

EXIT DELI "B" 

EXIT 

EXIT 

WOMEN 

F 

FE 

FHC 

UP 

DOWN 

MEN 

498.1 

EXIT 

UP TO 5 

SHOW 

COATS 

EXIT 

F 

FHC 

EXIT 

GATE 5 

12’ 10’ 

Job Exchange 

22’ 

213 

211 

209 

207 

205 

203 

201 

F 

Aisle 200 

10’ 

214 

212 

204 

202 

ENTRANCE 

SCALE 

0' 5' 10' 15' 20' 30' 40' 50' 60' 

313 

311 

FHC 

FE 

F 

Food & Beverage 

303 

301 

HALLS 4A & 4B 

44-10x10 booths 

154-4x8 posters 

Ceiling Height 25' 

Aisle widths 10' unless noted 

ASGT 14th Annual Meeting 

May 18-21. 2011 

Washington State Convention & Trade Center 

Seattle, Washington 

Aisle 300 

10’ 

NORTH 

314 

312 

304 

302 

15’ 

F 

15’ 

413 

411 

403 

401 

10’ 

10’ 

10’ 

10’ 

10’ 

10’ 

10’ 

10’ 

12’ 

10’ 

10’ 

Aisle 400 10’ 

FHC 

FE 

414 513 

412 511 

410 509 

408 507 

406 505 

404 503 

402 501 

F 

PUBLIC 

PHONES 

ENTRANCE 

Aisle 500 

10’ 

F 

SOUTH SERVICE CORRIDOR 

514 

512 

510 

508 

506 

504 

502 

439 

South 

Lobby 


40' 

Fill-in 

Kiosk 

FE 

FE 

FHC 

FE 

FE 

FHC 

438 

Internet Kiosks 

& Message Board 

PUBLIC 

PHONES 

Registration 

Storage Area 

BALCONY LINE ABOVE 

F 

F 

FHC 

FE 

EXIT 

UP TO 5 

FHC F SHOW 

EXIT 

F 

F 

CWF 

UP TO 5 & 6 

EXIT 

4A 

GATE 4 

EXIT 

MEN 

GRAND 

STAIRWAY 

FHC 

FE 

WOMEN 

GRAND 

STAIRWAY 

LOUNGE 

EXIT 

PU 

PH

78 

Exhibitor Descriptions 

Adaptive TCR Technologies 

307 Westlake Avenue N 

Suite 300 

Seattle, WA 98109 

Phone: (206) 659-0521 

Fax: (206) 659-0667 

E-mail: cdesmarais@adaptivetcr.com 

Website: www.adaptivetcr.com 

Booth Number: 504 

Adaptive’s TCR Profiling service provides a biochemical method 

for parallel sequencing of millions of TCRs with the data 

analysis capability of a secure proprietary relational database 

management system. Adaptive’s immunoSEQ system combines 

the capabilities of ultrahigh-throughput DNA sequencing 

with a proprietary sequencing methodology and a powerful 

bioinformatics software suite to provide exceptionally deep 

access to T cell repertoires. 

Aldevron 

3233 15th Street South 

Fargo, ND 58104 

Phone: (701) 499-7300 

Fax: (701) 280-1642 

E-mail: halland@aldevron.com 

Website: www.aldevron.com 


Aldevron is a world-leader in plasmid DNA, protein, and 

antibody production. Aldevron also provides DNA vaccine 

screening and genetic immunization (GIA) services. We 

manufacture biologics for research, clinical, and diagnostic 

applications. Aldevron also offers a broad portfolio of readyto-use 

plasmids including AAV helper, cytokine, and reporter 

vectors. Aldevron’s capacity and throughput capabilities support 

any project in bacterial, insect, and mammalian cell systems. By 

combining innovative technologies with best-in-class project 

management, our team ensures that we consistently exceed 

your expectations. 

AltheaDx 

3550 Dunhill Street 

San Diego, CA 92121 

Phone: (916) 812-0813 

E-mail: mclendenin@altheadx.com 

Website: www.altheadx.com 


AltheaDx is bringing theranostics into clinical use, with six 

companion diagnostic projects currently underway. The goal 

of AltheaDx is to reduce the time, risk, and cost of therapeutic 

development for our partners and to provide a clear path for 

development and commercialization of high-value companion 

diagnostic tests. 

American Society of Gene & Cell Therapy 

555 East Wells Street 

Suite 1100 

Milwaukee, WI 53202 

Phone: (414) 278-1341 

Fax: (414) 276-3349 

E-mail: info@asgct.org 

Website: www.asgct.org 

Booth Number: 505 & 507 

Stop by the ASGCT membership booth to find out where the 

2012 Annual Meeting will be held, pick up a copy of Molecular 

Therapy, and learn about the Society’s new strategic plan! 

Axis-Shield PoC 

PO Box 6863 Rodelokka 

Oslo, 0504 

Norway 

Phone: +4724056000 

Fax: +4724056010 

E-mail: bjh@axis-shield.com 

Website: www.axis-shield-density-gradient-media.com 


Axis-Shield will display a range of Density Gradient Media 

for the isolation of biological particles using centrifugation 

techniques. 

BioSpherix 

19 Demott Street 

Lacona, NY 13145 

Phone: (315) 387-3414 x 206 

Fax: (315) 387-3415 

E-mail: kbenedict@biospherix.com 

Website: www.biospherix.com 


BioSpherix will be exhibiting the Xvivo System, the world’s 

first and only point-of-care cGMP compliant cell and tissue 

incubation and processing systems for cell and gene therapy. 

For any application: explants or implants; minimal or maximal 

manipulation; autologous or allogeneic cells; pre or post 

biorepository. Stop by BioSpherix booth #301. 



Caliper Life Sciences 

68 Elm Street 

Hopkinton, MA 01748 

Phone: (508) 435-9500 

Fax: (508) 435-3439 

Website: www.caliperls.com 


Caliper Life Sciences is a leading supplier of technology for in 

vitro and in vivo applications in life science and drug discovery 

research. Caliper Products include both the IVIS and Maestro in 

vivo imaging platforms, and the Nuance multispectral imaging 

system for multiplexed fluorescence microscopy applications 

to study processes like disease progression or stem cell 

engraftment. 

Center for Cellular and Molecular 

Therapeutics at the Children’s Hospital of 

Philadelphia 

3501 Civic Center Blvd., Room 5059 

Colket Translational Research Building 

Philadelphia, PA 19104 

Phone: (267) 426-5256 

Fax: (215) 590-3660 

E-mail: sunj@email.chop.edu 


Our Center is dedicated to the understanding, development, 

and application of gene and cell therapies and the promotion 

of professional and public education in the field. The Center 

fosters a multidisciplinary approach to discover gene and cell 

therapies in search of cures for debilitating and life threatening 

childhood disorders. 

Data Unlimited International, Inc. 

15881-B Crabbs Branch Way 

Rockville, MD 20855 

Phone: (240) 631-7933 

Fax: (240) 631-7937 

E-mail: fkan@duii.com 

Website: www.duii.com 


Starfruit Technologies ® is software/database/computer/barcode 

for DNA diagnostic, genome/cancer research, immunogenetic 

labs – enables sample, patient, biorepository, billing databases; 

mutation, variant, disease, genotype databases, SNP databank; 

instrument interface, barcode, electronic signature, QA/ 

QC; worksheet, workflow, inventory, protocol, image; 

epidemiological frequency, trend, geographical distribution, 

disease/disorder susceptibility, reporting; comply with 21CFR11, 

CAP, CLIA, HIPPA, PHI. 

Freezerworks 

A Division of Dataworks Development, Inc. 

PO Box 174 

Mountlake Terrace, WA 98043 

Phone: (425) 673-1974 

Fax: (425) 673-2506 

E-mail: sales@freezerworks.com 

Website: www.freezerworks.com 


Specializes in sample management software and services 

in support of biorepositories, clinical trials and cancer 

research. Fully user configurable, Freezerworks safeguards 

data with powerful user and group security, integration 

tools, 21 CFR part 11 compliance, and cryogenic-safe bar code 

labeling. CaBig compatible. 

GENE TOOLS, LLC 

1001 Summerton Way 

Philomath, OR 97370 

Phone: (541) 929-7840 Ext. 1011 

Fax: (541) 929-7841 

E-mail: zli@gene-tools.com 

Website: www.gene-tools.com 


Gene Tools manufactures Morpholino oligos for blocking 

translation, modifying splicing or inhibiting miRNA activity. 

Morpholinos are used in cell cultures, embryos or, as Vivo- 

Morpholinos, in adult animals. Morpholinos are effective, 

specific, stable and non-toxic. Backed by Ph.D.-level customer 

support, Gene Tools designs and synthesizes Morpholinos and 

offers cytosolic delivery options. 

GENEWIZ, Inc. 

115 Corporate Blvd. 

South Plainfield, NJ 07080 

Phone: (877) 436-3949 Ext. 3206 

Fax: (908) 333-4511 

E-mail: jeffrey.shaman@genewiz.com 

Website: www.genewiz.com 


GENEWIZ, Inc. supports your needs for regulatory services 

from pre-clinical testing through biomanufacturing. Our DNA 

sequencing and molecular biology GLP services allow our 

clients to focus on their core capabilities while getting the 

design, preparation, testing, and data for the biologics needed 

in their therapeutic and diagnostic applications. For more 

information, contact GLP@genewiz.com. 


80 


Horizon Discovery Ltd 

Building 7300 

IQ Cambridge 

Cambridge, Cambridgeshire CB25 9TL 

United Kingdom 

Phone: 0044 1223655580 

Fax: 0044 1223862240 

E-mail: info@horizondiscovery.com 

Website: www.horizondiscovery.com 


Horizon Discovery employs its proprietary rAAV genome editing 

platform to modify human and mammalian cell lines. Products 

and services include OTS & custom X-MAN (gene-X, mutant 

and normal) isogenic human cell-lines, assays and diagnostic 

reagents. Horizon is applying its gene editing platform into 

additional areas including bioproduction and regenerative 

medicine. 

Lonza 

8830 Biggs Ford Rd. 

Walkersville, MD 21793 

Phone: (301) 898-7025 

Fax: (301) 845-4024 

E-mail: celltherapy@lonza.com 

Website: www.lonza.com 


Lonza offers world class technology platforms in the areas of 

GMP cell culture and viral-based therapeutic manufacturing, 

custom biotherapeutic culture media, a large selection of 

primary and stem cells and a full line of custom bioassays. 

Our extensive experience in Cell and GeneTherapy process 

optimization and scale-up innovation helps clients to safely and 

effectively advance their products through all phases of the 

commercial pipeline and maximize their return on investment. 

Lovelace Respiratory Research Institute 

2425 Ridgecrest Drive SE 

Albuquerque, NM 87108 

Phone: (505) 348-9456 

Fax: (505) 348-4983 

E-mail: wbechtol@lrri.org 

Website: www.lrri.org 


The Lovelace Respiratory Research Institute is a private not-forprofit 

biomedical research organization. Lovelace offers animal 

models of disease, evaluation of efficacy of potential new 

therapeutics, and pre-clinical assessments including evaluation 

of pharmacokinetics/biodistribution in large and small animal 

models. Studies are routinely performed under GLP guidelines. 

Mary Ann Liebert, Inc. 

140 Huguenot Street, 3 rd Floor 

New Rochelle, NY 10801 

Phone: (914) 740-2100 

Fax: (914) 740-2101 

E-mail: info@liebertpub.com 

Website: www.liebertpub.com 


Mary Ann Liebert, Inc., publishes authoritative journals in 

new and promising areas of science and biomedical research 

including Human Gene Therapy, (www.liebertpub.com/hum); 

official journal of 9 international societies; named one of the 

100 most influential Journals in Biology & Medicine over the last 

100 years! Visit us at booth #412. 

Meridian Life Science, Inc. 

3471 River Hills Drive 

Cincinnati, OH 45244 

Phone: (513) 271-3700 

Fax: (513) 271-3762 

E-mail: shirley.torrence@meridianbioscience.com 

Website: www.meridianlifescience.com 


MolMed S.p.A. 

Via Olgetinna, 58 

Milan, 20132 

Italy 

Phone: +39 0221277257 

Fax: +39 0221277325 

Email: simona.laseta@molmed.com 

Website: www.molmed.com 


MolMed is a medical biotechnology company focused 

on research, development and clinical validation of novel 

antitcancer therapies with also key expertise in cell and gene 

therapy. MolMed’s service area, GMP Solutions, provides tailormade 

services for manufacturing of patient-specific cells 

and genetically modified cells, and active pharmaceutical 

ingredients for clinical use. 



NanoSight 

6660 N. High Street, Suite 2A 

Worthington, OH 43085 

Phone: (614) 888-0023 

Fax: (614) 987-0045 

E-mail: colleen.munhall@nanosight.com 

Website: www.nanosight.com 


NanoSight manufactures instruments for Counting, Sizing and 

Visualizing Nanoparticles from 10 nm to 2.0 µm. Applications 

include measuring viral titre, Labeled and unlabeled Exosomes, 

Protein aggregation kinetics and all types of metal colloids. 

Nanoparticle Tracking Analysis (NTA) visualizes the particles being 

analyzed which enables the operator to perform an immediate 

qualitative examination of the particles being measured. 

National Gene Vector Biorepository (NGVB) 

980 W. Walnut Street, R3 C602 

Indianapolis, IN 46202-5188 

Phone: (317) 274-4519 

Fax: (317) 278-3327 

E-mail: lrubin@iupui.edu 

Website: https://www.ngvbcc.org 


The National Gene Vector Biorepository provides support for 

gene therapy research by offering several services. Check out 

the reagent repository comprising cell lines, plasmids and other 

tools used in gene therapy research. There are archiving services 

to meet FDA requirements. The NGVB will store clinical post-trial 

samples, final product reserves, and master cell banks as well 

as pharmacology/toxicology samples. A pharm/tox database 

containing gene therapy tox studies is a valuable resource. We 

offer assistance with insertional mutagenesis analysis through 

the SeqMap Bioinformatic Tool as well as LAM-PCR and other 

testing services. Go to https://www.ngvbcc.org or come and 

see us in Booth 205. 

Nature Publishing Group 

75 Varick Street, 9 th Floor 

New York, NY 10013 

Phone: (212) 726-9200 

E-mail: institutions@nature.com 

Website: www.nature.com 


Nature Publishing Group brings leading scientific and medical 

research to your desk top. The NPG portfolio combines the 

continued excellence of Nature, its associated research and 

review journals, and 50 leading academic and society journals 

in the life, physical and clinical sciences. Visit Booth 402 for free 

sample copies. 

Nature Technology Corporation 

4701 Innovation Dr. 

Lincoln, NE 68521 

Phone: (402) 472-6530 

Fax: (402) 472-6532 

E-mail: jvincent@natx.com 

Website: www.natx.com 


Nature Technology Corporation is a discovery-based 

bioengineering technology company, providing industry 

partners with safe and efficacious non-viral vectors (plasmids) 

and processes for gene therapy and DNA vaccination research. 

NTC’s molecular services include vector construction, plasmid 

DNA manufacturing and recombinant proteins. 

Nexcelom Bioscience 

360 Merrimack Street, Bldg. #9 

2nd Floor 

Lawrence, MA 01843 

Phone: (978) 327-5340 

Fax: (978) 327-5341 

E-mail: lvavra@nexcelom.com 

Website: www.nexcelom.com 


Nexcelom’s Cellometer line of simple-to-use cell counters 

automate manual cell counting procedures by obtaining 

accurate counts, viability, and cell sizes in less than 30 seconds & 

only 20uL of sample. Fluorescence detection capabilities enable 

fast & simple determination of GFP transfection rates, PI-viability, 

& direct counting of WBCs without lysing. 

NHLBI Gene Therapy Resource Program 

2 Rockledge Center 

6701 Rockledge Drive 

Bethesda, MD 20892-7940 

Phone: (301) 435-0477 

Fax: (301) 628-1929 

E-mail: gtrpccc@s-3.com 

Website: www.gtrp.org 


The NHLBI Gene Therapy Resource Program (GTRP) facilitates 

the translation of gene therapy research into clinical 

interventions primarily in heart, lung, and blood diseases. 

Services provided by the Program include preclinical and 

clinical-grade vector production, pharmacology/toxicology 

testing, immunology testing, regulatory support, and clinical 

trial funding assistance. 


82 


NIH Office of Biotechnology Activities 

6705 Rockledge Dr., Suite 750 

Bethesda, MD 20892-7985 

Phone: (301) 496-9838 

Fax: (301) 496-9839 

E-mail: oba@od.nih.gov 

Website: http://oba.od.nih.gov 


NIH Office of Biotechnology Activities staff will be available 

to answer questions about the oversight of recombinant 

DNA research and the requirements for Institutional 

Biosafety Committees (IBCs) under the NIH Guidelines for 

Research Involving Recombinant DNA Molecules. In addition, 

information will be available on dual use research in the life 

Sciences. Informative materials and handouts related to both 

recombinant DNA and dual use research will be available. 

Omnia Biologics, Inc. 

12111 Parklawn Drive 


Phone: (301) 984-5928 

Fax: (301) 984-2515 

E-mail: scardak@omniabiologics.com 

Website: www.omniabiologics.com 


Omnia Biologics provides cost effective outsourcing of product 

development services to the biotechnology, pharmaceutical, 

and academic biologic drug developers. These services 

include process development, cGMP cell and virus banking, 

comprehensive cGMP manufacturing services, BSL-3 

containment, assay development, formulation and fill/finish. 

Omnia has experience with a variety of vaccine, gene therapy 

and protein therapeutic platforms. 

Penn Vector Core, University of Pennsylvania 

Gene Therapy Program 

125 South 31st Street, Suite 2000 

Philadelphia, PA 19104-3403 

Phone: (215) 573-0633 

Fax: (215) 573-0300 

E-mail: aksandhu@mail.med.upenn.edu 

Website: http://www.med.upenn.edu/gtp/vectorcore/ 


The Penn Vector Core is a full service viral vector core facility 

specializing in the production of novel AAV serotype vectors. With 

over a decade of production and development experience, the 

Core is a key resource for investigators interested in the use of 

vector tools for gene transfer applications. 

Polyplus-transfection 

Blvd S. Brant 

Bioparc 

Illkirch 

Bas Rhin 

67400 

France 

Phone:+33 (0) 390 406 474 

Fax: +33 (0) 390 406 181 

E-mail: latayi@polyplus-transfection.com 

Website: www.polyplus-transfection.com 


Polyplus-transfection is a Biotech company dedicated to the R 

& D and marketing of transfection reagents. Polyplus provides 

state-of-the-art quality reagents for standard in vitro DNA 

transfection to human gene therapy, as well as for protein 

production in synthetic medium, siRNA delivery and protein 

delivery in living cells. 

Production Assistance for Cellular 

Therapies (PACT) 

401 N. Washington Street, Suite 700 


Phone: (301) 251-1161 

Fax: (240) 306-2527 

E-mail: pactinfo@pactgroup.net 

Website: www.pactgroup.net 


The Production Assistance for Cellular Therapies (PACT) program 

is an NHLBI-funded initiative created to provide assistance with 

cellular therapy translational research and the manufacture of 

cellular therapy products through funded contracts with five 

GMP cell processing facilities and a Coordinating Center. Visit 

the PACT website at www.pactgroup.net for more information. 

ReGenX Biosciences 

750 17th Street, NW, Suite 1100 

Washington, DC 20006 

Phone: (202) 778-2365 

Fax: (202) 785-7439 

E-mail: jbrown@regenxbio.com 

Website: www.regenxbio.com 


ReGenX BioSciences is leading the effort to translate promising 

gene delivery applications into a pipeline of next generation 

personalized therapies for a range of severe diseases with 

serious unmet needs. ReGenX’s NAV gene delivery technology 

includes recombinant adeno-associated viral (rAAV) vectors that 

offer a platform for safer, highly efficient and specific expression 

of biologics with therapeutic effect. 



Social & Scientific Systems, Inc. 

8757 Georgia Avenue, 12th Floor 

Silver Spring, MD 20910 

Phone: (301) 628-3000 

Fax: (301) 628-3001 

E-mail: tcockrell@s-3.com 

Website: www.s-3.com 


St. Jude Children’s Research Hospital 

262 Danny Thomas Place 

Memphis, TN 38105 

Phone: (901) 595-2750 

Fax: (901) 595-5376 

E-mail: fellowships@stjude.org 

Website: www.stjude.org/fellowships 


St Jude Children’s Research Hospital is a non-profit biomedical 

research institution in Memphis, TN, where 190 basic science 

and clinical researchers investigate the molecular basis of both 

normal cellular and diseased processes. Visit our booth to 

discuss and apply for Postdoctoral Fellowship positions. 

Techulon, Inc. 

2200 Kraft Drive, Suite 2475 

Blacksburg, VA 24060 

Phone: (415) 602-0481 

Fax: (206) 202-0418 

E-mail: frank.akers@techulon.com 

Website: www.techulon.com 


Techulon provides Glycofect polymer-based transfection 

reagents that deliver DNA and RNA into cells with lower cell 

toxicity and high protein expression. In addition to selling 

delivery reagents Techulon is seeking collaborators for 

therapeutically relevant applications. Free samples are available 

for a limited time. 

TriLink BioTechnologies, Inc. 

9955 Mesa Rim Road 

San Diego, CA 92121 

Phone: (858) 546-0004 

Fax: (858) 546-0020 

E-mail: bgrajkowski@trilinkbiotech.com 

Website: www.trilinkbiotech.com 


TriLink BioTechnologies manufactures custom oligonucleotides, 

modified nucleoside triphosphates and CleanAmp PCR 

products. In addition, custom chemistry, contract research 

services and ISO/QSR compliant cGMP production facilities 

are offered. TriLink’s strong proficiency in nucleoside and 

oligonucleotide chemistry means high purity, modified 

compounds and expert technical support. For more information 

visit www.trilinkbiotech.com. 

Waisman Biomanufacturing 

1500 Highland Avenue 

Madison, WI 53705 

Phone: (608) 263-8940 

Fax: (608) 263-5725 

E-mail: info@GMPbio.org 

Website: www.GMPbio.org 


Waisman Biomanufacturing is a dedicated manufacturing 

facility that provides cGMP manufacturing services for 

producing gene and cell therapeutics for early-stage human 

clinical trials. Services that are provided by the WCBF range from 

process development to clinical production and product fill and 

finish and release testing, with full quality system support. 


84 

Exhibitor Information 

General Information 

The Exhibit Hall is located in Hall 4B of the Washington 

State Convention Center. All participants are urged to allow 

adequate time in your daily schedule to visit the exhibits. The 

companies, organizations and institutions exhibiting at the 

ASGCT 14 th Annual Meeting will be providing you with the latest 

information on products and services directly related to your 

professional needs, as well as recruiting for open positions. 

Exhibit Dates 

Exhibits will be open Wednesday, May 18 through Friday, May 

20, 2011. 

Exhibitor Registration 

The Exhibitor Registration Desk is located across the hallway 

from Hall 4B. 

Exhibitor Registration Desk Hours 





Exhibit Move In 


Exhibit Hall Hours 


Thursday, May 19 10:15 am – 11:00 am 


Friday, May 20 9:15 am – 10:00 am 


Exhibit Move Out 


Note: All exhibit booths must be staffed during hall hours. 

Packing of equipment/literature and the dismantling of exhibits 

will not be permitted until after 6:40 pm on Friday, May 20, 2011. 

Exhibitor Badge Policy 

Admission to the Exhibit Hall will be by name badge only. 

Security guards will monitor exhibit hall entrances for proper I.D. 

Exhibit booth personnel must show an official ASGCT exhibitor 

name badge in order to gain access to the exhibit hall during 

installation, show, or dismantlement hours. Independent 

contractor personnel, hired by an exhibitor to install and 

dismantle their display, do not need to show exhibitor badges, 

but should possess identification that they are employed by 

the independent contractor. If independent contractors do not 

possess proper identification, they should obtain a name badge 

at the on-site exhibitor registration desk. 

Endorsement Disclaimer 

Products and services displayed in the Exhibit Hall or advertised 

in this program occur by contractual business arrangements 

between the ASGCT and participating companies and 

organizations. These arrangements do not constitute or imply 

an endorsement by the ASGCT of these products and services. 


Seattle Fun Facts 

Seattle Information 

Seattle is two cities in one. It’s a world-class metropolis set within wild, beautiful natural surroundings, offering the best of urban 

lifestyle while embracing the rugged outdoors—Seattle is a true metronatural city. 

Many of Seattle’s top visitor attractions are within mere blocks of the Washington State Convention Center, including the Pike 

Place Market, Pioneer Square, Seattle Art Museum, Seattle Symphony, water tours, ferries, world-class restaurants and repertory 

and musical theaters. Three national parks lie within a two-hour drive of Seattle and the city is a gateway to the San Juan Islands, 

Olympic Peninsula, Washington Wine Country and British Columbia. 

Pike Place Market – Situated just above the waterfront, the 

market is popular with natives and tourists alike. A vital part 

of Seattle’s economy, the market features more than 200 

businesses, including farmers and merchants offering fresh 

vegetables, seafood, food bars, cafes, restaurants, crafts, art work, 

and gifts. Home of the original Starbucks®, the market was born 

in 1907 and is the oldest continually operating farmers’ market 

in the USA. 

Pioneer Square – Seattle’s oldest neighborhood is a 20-squareblock 

National Historic District. Its charming buildings have 

been restored and now hold a great arts, café, shopping, and 

nightlife scene. 

Seattle Center & the Space Needle – The Seattle Center was 

built as the United States Science Pavilion for the Seattle World’s 

Fair of 1962. This complex on 74-acres is home to the 11 theaters, 

five gardens, six fountains, restaurants, a skate park and an events 

area. The center is also home to The Space Needle, which opened 

on the first day of the World Fair, features an observation deck, 

restaurant and cocktail bar. This most recognizable landmark 

in Seattle can be reached by a 90-second monorail ride from 

downtown’s Westlake shopping center. 

The Seattle Waterfront – The waterfront is a bustling 

collection of attractions, restaurants and shopping. It is also the 

starting point for ferries and cruise ships, including the Victoria 

Clipper and Argosy boat tours which are located here. Feed the 

seagulls, stroll by the wooden piers of Waterfront Park, admire 

the view or shop for souvenirs. Also located on the waterfront is 

the Olympic Sculpture Park, a must-do for visitors who want 

to experience art outdoors while enjoying incredible views 

of the Olympic Park Mountains, Puget Sound, and Seattle’s 

cityscape. 

For more information on Seattle, WA and area attractions stop 

by the Seattle Convention & Visitors Bureau’s Concierge 

Desk in the Washington State Convention Center or your hotel’s 

concierge desk. 

Please note, the City of Seattle issues jaywalking tickets to 

individuals who do not follow the traffic laws. Therefore, please 

abide by the traffic signs and lights and utilize the designated 

crosswalks at all times. 


86 

Housing Information and Map of Seattle 

1) Sheraton Seattle – Headquarters Hotel 

1400 Sixth Avenue 

Seattle, Washington 98101 

Phone: (206) 621-9000 

2) Grand Hyatt Seattle 

721 Pine Street 


Phone: (206) 774-1234 

W Republican St 

W Harrison St 

W Thomas St 

John St 

Elliott Avenue 

Terminal 91 

Pier 70 

Queen Anne 

Ave N 

Olympic 

Sculpture Park 

Victoria Clipper 

1st Ave N 

Pier 69 

Pier 67 

Roy St 

SEATTLE 

CENTER 

2nd Ave N 

Broad St 

Alaskan Way 

Cedar St 

Vine St 

Wall St 

Mercer St 

Clay St 6th Ave N 

Bell Harbor International 

Conference Center 

Pier 66/Bell St. 

Cruise Terminal 

Ferry to Tillicum Village 

* 

Space 

Needle 

Experience 

Music Project 

Tilikum Place 

Battery St 

Pier 62 & 63 

Elliott Bay 

Republican St 

Harrison St 

5th Ave N 

Taylor Ave N 

Bell St 

Western Ave 

Ferry to Bainbridge Island 

Denny Way 

5th Ave 

Blanchard St 

Pier 59 

4th Ave 

Lenora St 

1st Ave 

Seattle Aquarium 

Ferry to Bremerton 

Regrade Park 

Steinbrueck 

Park 

Waterfront Park 

Pier 57 

Pier 56 

Pier 55 

sland 

Aurora Ave N 

6th Ave 

2nd Ave 

3) Hyatt at Olive 8 

1635 8th Avenue 


Phone: (206) 695-1234 

4) The Westin Seattle 

1900 5th Avenue 


Phone: (206) 728-1000 

To Lake Union 

Dexter Ave N 

Thomas St 

7th Ave 

3rd Ave 

Pier 54 

John St 

PIKE PLACE MARKET 

Pier 52 

8th Ave 

WA State 

Ferries 

Pine St 

9th Ave 

Union St 

Post Alley 

Virginia St 

Terry Ave 

Olive Way 

University St 

Seneca St 

Spring St 

Marion St 

Madison St 

Columbia St 

Minor Ave 

Howell St 


8th Ave N 

Pier 48 

9th Ave N 

Pike St 

Westlake Ave N 

4 

Terry Ave N 

Westlake 

Park 

Boren Ave N 

Stewart St 

Fairview Ave N 

Bus 

Terminal 

Pioneer 

Square Park 

LEGEND 

1. Sheraton Seattle Hotel 

2. Grand Hyatt Seattle 

3. Hyatt at Olive 8 

4. Westin Seattle Hotel 

3 

1 

2 

Occidental 

Square 

Minor Ave N 

4th Ave 

PIONEER 

CONVENTION CENTER 

Citywide Concierge 

& Visitor Center 

5th Ave 

City Hall 

Park 

Freeway Park 

6th Ave 

7th Ave 

8th Ave 

Jefferson St 

3rd Ave S 

2nd Ave S 

Boren-Pike-Pine Park 

Terrace 

9th Ave 

Terry Ave 

Cherry St 

NORTH 

James St 

Kobe 

Terrace 

Park 

Summit Ave 

Boren Ave 

Boylston Ave 

Minor Ave 

Alder St 

Yesler Way 

Broadway Ave 

S Washington St 

S Main St 

S Jackson St

Abstract Directory Wednesday, May 18, 2011 


Adenovirus and Other DNA Virus Vectors I: 

Virus Entry 

3:15 PM - 5:15 PM 

Room: 606-607 

1 3:15 PM 

Retargeting Parvovirus B19 to HER2/neu-Positive Cells for 

Breast Cancer Treatment 

Harald G. P. Messer, Yiwen Xiang, Mavis Agbandje-McKenna, 

Kirsten A. K. Weigel-Van Aken. 

2 3:30 PM 

Identification of the Receptor for Adenovirus Serotypes 3, 

7, 11, and 14: Structural Analysis of Adenovirus – Receptor 

Interaction 

Hongjie Wang, ZongYi Li, Jonas Persson, Ines Beyer, Robert 

Strauss, Akseli Hemminki, Pascal Fender, Andre Lieber. 

3 3:45 PM 

Multi-Year Transgene Expression in Nonhuman Primates 

Following Hepatic Transduction with Helper-Dependent 

Adenoviral Vectors 

Nicola Brunetti-Pierri, Gary Stapleton, Thomas Ng, David 

Iannitti, William Cioffi, Mark Law, John Breinholt, Donna 

Palmer, Nathan Grove, Milton Finegold, Arthur Beaudet, 

Charles Mullins, Philip Ng. 

4 4:00 PM 

The Refinement of the Molecular Model of Adenovirus 

Binding to Blood Coagulation Factors and the Role of This 

Interaction in Virus Recognition by the Host 

Konstantin Doronin, Justin Flatt, Steffen Lindert, Dewight R. 

Williams, Phoebe L. Stewart, Dmitry M. Shayakhmetov. 

5 4:15 PM 

Suppression of Protein Phosphatase 2A Activity Enhances 

Ad5/F35 Adenovirus Transduction Efficiency in Human 

Normal B Lymphocytes and Cell Lines 

Marie-Pierre Cayer, Mélanie Samson, Claudia Bertrand, Nellie 

Dumont, Mathieu Drouin, Daniel Jung. 

6 4:30 PM 

Basic Residues in the Heparin-Binding Exosite of the 

Factor X Serine Protease Domain Mediate Ad5/FX Complex 

Binding to Hepatocytes 

Margaret R. Duffy, Angela C. Bradshaw, John H. McVey, Alan L. 

Parker, Andrew H. Baker. 

7 4:45 PM 

GSK3beta-Mediated Regulation of the Coxsackie- 

Adenovirus Receptor Influences Adenovirus Infection 

Priyanka Sharma, Kathleen Frondorf, Katherine J. D. A. 

Excoffon. 

8 5:00 PM 

Mining the Adeno-”Virome” for Effective Oncolytics 

Against Solid Tumors and Leukemias 

Chris Y. Chen, Julien S. Senac, Eric A. Weaver, Reeti Khare, 

Shannon M. May, Michael A. Barry. 



3:15 PM - 5:15 PM 

Room: 6A 

9 3:15 PM 

Chromatin Structure Effects on Integration of 

Gammaretroviruses MLV and XMRV 

Shoshannah L. Roth, Nirav Malani, Troy Brady, Charles Berry, 

Frederic Bushman. 

10 3:30 PM 

Elimination of Gene Targeted Chromosome in Trisomic Cells 

Li Li, Kai-Hsin Chang, Roli Hirata, Gaoying Ren, Andy Herman, 

Thalia Papayannopoulou, David Russell. 

11 3:45 PM 

Towards Eliciting the Mechanism of Plasmid DNA Silencing 

In Vivo 

Jiamiao Lu, Mark Kay. 

12 4:00 PM 

Development of a High-Throughput Quantitative Method 

for Assessing Plasmid Nuclear Import 

Holly M. Reynolds, David A. Dean. 

13 4:15 PM 

Robust Long-Term Gene Expression in Mouse Liver Via the 

Novel hAT Transposon TcBuster 

Lauren E. Woodard, Aparna Kaja, Robert H. Hice, Peter W. 

Atkinson, Nancy L. Craig, Matthew H. Wilson. 

14 4:30 PM 

Immunosuppression with Cyclophosphamide Significantly 

Prolongs High-Level Expression of IDUA Mediated by the 

Sleeping Beauty Transposon System 

Elena L. Aronovich, Jason B. Bell, Kelly M. Podetz-Pedersen, 

Brenda L. Koniar, R. Scott McIvor, Perry B. Hackett. 

15 4:45 PM 

Evaluating the Safety of PiggyBac Mediated Gene Transfer 

in Human Cells 

Sunandan Saha, Aparna Kaja, Cliona M. Rooney, Matthew H. 

Wilson. 

16 5:00 PM 

Development of a Sleeping Beauty Transposon-Based 

Integration System for Gene Transfer in Human Epithelial 

Cells 

Giandomenico Turchiano, Maria Carmela Latella, Zsuzsanna 

Izsvak, Zoltan Ivics, Fulvio Mavilio, Alessandra Recchia. 


Wednesday, May 18


88 



Infectious Diseases and Vaccines 

3:15 PM - 5:15 PM 

Room: 615-617 

17 3:15 PM 

Induction of T Cell Dysfunction by AAV-Mediated Hepatitis 

B Virus Infection 

Mi-Hua Tao, Ya-Hui Huang, Ho-Yuan Chou, Cheng-Chieh Fang. 

18 3:30 PM 

Desmoglein 2 Is a Receptor for Adenovirus Serotypes 3, 7, 

11, and 14: Implications for Pathogenesis of Adenovirus 

Infections and Cancer Treatment 

Hongjie Wang, ZongYi Li, Jonas Persson, Ines Beyer, Robert 

Strauss, Akseli Hemminki, Pascal Fender, Andre Lieber. 

19 3:45 PM 

Increased Mucosal CD4 + T Cell Activation Following 

Vaccination with a Species-Specific Adenovirus Vector in 

Rhesus Macaques 

Roberto Calcedo, Irene Bukh, Soumitra Roy, Diane G. 

Carnathan, Rebecca Grant, Sarah J. Rutcliffe, James M. Wilson, 

Michael R. Betts. 

20 4:00 PM 

Most Closely HLA-Matched Allogeneic Virus Specific 

Cytotoxic T-Lymphocytes (CTL) To Treat Persistent 

Reactivation or Infection with Adenovirus, CMV and EBV 

after Hemopoietic Stem Cell Transplantation (HSCT) 

Ann M. Leen, Catherine M. Bollard, Adam M. Mendizabal, 

Elizabeth J. Shpall, Paul Szabolcs, Joseph Antin, Neena 

Kapoor, Sung-Yun Pai, Bambi Grilley, Adrian P. Gee, Malcolm 

K. Brenner, Cliona M. Rooney, Helen E. Heslop. 

21 4:15 PM 

Modeling Genetic Protection Against AIDS: Viral Restriction 

Factor Transgenesis in the Domestic Cat 

Pimprapar Wongsrikeao, Dyana T. Saenz, Tommy Rinkoski, 

Takeshige Otoi, Eric M. Poeschla. 

22 4:30 PM 

Induction of Strong Cellular and Humoral Immune 

Responses Following Immunotherapy of Post-LEEP CIN 2/3 

with HPV 16 & 18 E6/E7 DNA Vaccines 

Jian Yan, Xuefei Shen, Mary Giffear, Jessica Lee, Amir S. Khan, 

Dawn Harris, Panyupa Pankhong, Devon Shedlock, Jean 

Boyer, David B. Weiner, Mark Bagarazzi, Niranjan Y. Sardesai. 

23 4:45 PM 

Enhanced Immunogenicity of Measles Virus Constructs 

Encoding Helicobacter pylori Neutrophil-Activating Protein 

as Vaccine Platforms 

Ianko D. Iankov, Mark J. Federspiel, Evanthia Galanis. 

24 5:00 PM 

In Vivo Safety and Efficacy of a Combination Anti-HIV 

Lentiviral Vector in RAG1 Mice for HIV Gene Therapy 

Jon Walker, Brian Fury, Jeannine McGee, Gerhard Bauer, Jan A. 

Nolta, Joseph S. Anderson. 




3:15 PM - 5:15 PM 

Room: 611-612 

25 3:15 PM 

Genetically Modified T Cells Directed to Glioblastoma 

Suppress Tumor Growth in a Rodent Glioma Model 

Seogkyoung Kong, Betty Tyler, Jinyuan Zhou, Bob S. Carter, 

Henry Brem, Richard P. Junghans, Prakash Sampath. 

26 3:30 PM 

Disruption of HLA Expression To Enable Allogeneic Cells To 

Escape Immune Recognition 

Hiroki Torikai, Andreas Reik, Frank Soldner, Carrie Yuen, 

Yuanyue Zhou, Denise Kellar, Helen Huls, Edus H. Warren, 

Scott S. Tykodi, Michael C. Holmes, Edward J. Rebar, Dean A. 

Lee, Richard E. Champlin, Philip D. Gregory, Rudolf Jaenisch, 

Laurence J. N. Cooper. 

27 3:45 PM 

A Chimeric Antigen Receptor Molecule Mediates Bispecific 

Activation and Targeting of T Lymphocytes 

Zakaria Grada, Meenakshi Hegde, Donald R. Shaffer, Alexia 

Ghazi, Tiara Byrd, Giampietro Dotti, Winfried Wels, Matthew 

Baker, Helen E. Heslop, Stephen Gottschalk, Nabil Ahmed. 

28 4:00 PM 

Drug Resistant γδ T Cells Are Required to Efficiently 

Kill Drug Resistant Glioblastoma Multiforme during a 

Chemotherapy Challenge 

Anindya Dasgupta, Harold T. Spencer, George Y. Gillespie, Yun 

Su, Joscelyn E. Bowersock, Lawrence S. Lamb. 

29 4:15 PM 

Redirected Allogeneic T Cells for Adoptive Cell Therapy of 

Cancer 

Assaf Marcus, Tova Waks, Zelig Eshhar. 

30 4:30 PM 

Optimization of a Gamma-Retroviral Vector Co-Expressing 

a Prostate-Specific Membrane Antigen-Targeted Chimeric 

Antigen Receptor (PSMA-CAR) and HSVTK for the 

Treatment of Metastatic Prostate Cancer 

Xiuyan Wang, Oriana Borquez-Ojeda, Jolanta Stefansk, Jason 

Plotkin, Steven Poon, Jinrong Qu, Teresa Wasielewska, Larrisa 

Shenker, Vladimi Ponomarev, Susan Slovin, Michel Sadelain, 

Isabelle Rivière.


ORAL ABSTRACT SESSION 133 — continued 


3:15 PM - 5:15 PM 

Room: 611-612 

31 4:45 PM 

Specific Targeting of Interleukin-13 (IL-13) Receptor α2- 

Positive Tumor Cells with Lentiviral Vectors Displaying IL-13 

Wu Ou, Michael P. Marino, Bharat Joshi, Andrea Maisner, 

Evanthia Galanis, Raj K. Puri, Jakob Reiser. 

32 5:00 PM 

Serial Transplantation of MGMTP140K-Transduced Bone 

Marrow and Dose-Intense Chemotherapy Selects for 

Clones with Distinct Insertions 

Frank A. Giordano, Ursula R. Sorg, Jens-Uwe Appelt, Nico 

Lachmann, Stephanie Bleier, Ingo Roeder, Veronika Kleff, W. 

Jens Zeller, Heike Allgayer, Christof von Kalle, Stefan Fruehauf, 

Thomas Moritz, Stephanie Laufs. 


Novel Approaches for Gene Regulation & 

Genome Modification 

3:15 PM - 5:15 PM 

Room: 618-620 

33 3:15 PM 

Identification and Characterization of New Chromatin 

Insulators for Gene Therapy Vectors 

David W. Emery, Amy C. Groth, Mingdong Liu, Hao Wang, 

John Stamatoyannopoulos, George Stamatoyannopoulos. 

34 3:30 PM 

TALE-Based Designer Nucleases: A Novel Platform To Edit 

the Human Genome 

Claudio Mussolino, Fabienne Luetge, Robert Morbitzer, 

Thomas Lahaye, Toni Cathomen. 

35 3:45 PM 

Engineering XID(Btk) Site Specific I-Anil Homing 

Endonuclease for Gene Repair in Hematopoietic Stem Cells 

Yupeng Wang, Jordan Jarjour, James Havranek, Summer 

Thyme, David Baker, Andrew M. Scharenberg, David J. 

Rawlings. 

36 4:00 PM 

Human Cardiac Troponin T Regulatory Cassettes Facilitate 

High-Level Transient Expression in Differentiating Skeletal 

Muscle and Continuous Expression in Cardiac Muscle 

Xiaolan Chen, Quynh V. Nguyen, Guy L. Odom, Eric E. Finn, 

Robert E. Welikson, John C. Angello, Jeffrey S. Chamberlain, 

Stephen D. Hauschka. 

37 4:15 PM 

Modifying Target Structure Greatly Improves the Efficiency 

of microRNA-Regulated Vectors 

Alessia Baccarini, Hemangina Chauhan, Thomas Gardner, 

Albert Ruzo, Ravi Sachidanandam, Brian Brown. 

38 4:30 PM 

A Transgene Encoded Cell Surface EGFR Polypeptide for 

Selection, In Vivo Tracking and Ablation of Engineered Cells 

Xiuli Wang, Wen-Chung Chang, ChingLam W. Wong, David 

Colcher, Mark Sherman, Julie R. Ostberg, Stanley R. Riddell, 

Stephen J. Forman, Michael C. Jensen. 

39 4:45 PM 

Evaluation of an AAV2-Based Rapamycin-Regulated Glial 

Cell-Derived Neurotrophic Factor (GDNF) Expression Vector 

System 

Piotr Hadaczek, Janine Beyer, Wade Narrow, William Bowers, 

Howard J. Federoff, John Forsayeth, Krystof S. Bankiewicz. 

40 5:00 PM 

Targeted Delivery of IDUA across the Blood-Brain Barrier 

for Treatment of MPS Type I 

Daren Wang, Alex Kuan, David Hui, Dao Pan. 


Genetic and Metabolic Diseases 

Gene & Cell Therapy I 

3:15 PM - 5:15 PM 

Room: 608-609 

41 3:15 PM 

Correction of Murine Rag Deficiencies by Self-Inactivating 

Lentiviral Vector-Mediated Gene Transfer 

Karin Pike-Overzet, Mark Rodijk, Yuk-Yin Ng, Miranda R. M. 

Baert, Chantal Lagresle, Axel Schambach, Rob C. Hoeben, 

Salima Hacein-Bey-Abina, Arjen C. Lankester, Robbert G. M. 

Bredius, Gertjan J. A. Driessen, Christopher Baum, Marina 

Cavazzana-Calvo, Jacques J. M. van Dongen, Frank J. T. Staal. 

42 3:30 PM 

Distribution of Lentiviral Vectors in Gene Therapy for 

X-Adrenoleukodystrophy 

Cynthia C. Bartholomae, Nathalie Cartier, Salima Hacein-Bey 

Abina, Ina Kutschera, Maximilian Schliesser, Bruno l’Homme, 

Alain Fischer, Marina Cavazzana-Calvo, Patrick Aubourg, 

Manfred Schmidt, Christof von Kalle. 

43 3:45 PM 

Integration Site Analysis in a Benign Hemangioma 

That Developed in the Spleen at 8 Years after Neonatal 

IV Injection of a gamma Retroviral Vector into a 

Mucopolysaccharidosis VII Dog 

Katherine P. Ponder, Thomas O’Malley, Anna Paruzynski, 

Christina Lulay, Manfred Schmidt, Christof von Kalle, Patricia 

O’Donnell, Mark E. Haskins. 


Wednesday, May 18


90 





3:15 PM - 5:15 PM 

Room: 608-609 

44 4:00 PM 

Repeated Lentivirus-Mediated G-CSF Delivery To Treat 

Canine Cyclic Neutropenia 

Ofer Yanay, Cheryl Adler, David C. Dale, William R. Osborne. 

45 4:15 PM 

Balloon Delivery of Helper-Dependent Adenoviral Vector 

Results in Sustained hFIX Expression in Rhesus Macaques 

Nicola Brunetti-Pierri, Amiee Liou, Priti Patel, Donna Palmer, 

Nathan Grove, Karen Rice, Milton Finegold, Arthur Beaudet, 

Charles Mullins, Philip Ng. 

46 4:30 PM 

Outcomes of AAV8 and AAV5-Mediated Fetal Gene Transfer 

at 0.9G in Non-Human Primates 

Citra N. Mattar, Amit Nathwani, Simon Waddington, Niraja 

Dighe, Christine Kaeppel, Ali Nowrouzi, Jenny Mcintosh, 

Nuryanti Johana, Nicholas Fisk, Andrew Davidoff, Jens-Uwe 

Appelt, Christof von Kalle, Manfred Schmidt, Arijit Biswas, 

Mahesh Choolani, Jerry K. Y. Chan. 

47 4:45 PM 

Longterm and Sustained Knockdown of Mutant AAT along 

with Simultaneous Augmentation of Wildtype AAT with a 

Single Dual Function Vector Has Minimal Effect on Global 

Liver miRNA Profiles 

Christian Muller, Qiushi Tang, Lina Song, Phillip D. Zamore, 

Terence R. Flotte. 

48 5:00 PM 

In Vivo AAV-Mediated Gene Repair Is Enhanced by the DNA- 

PK Inhibitor Vanillin 

Nicole K. Paulk, Milton Finegold, Markus Grompe. 


Late Oral Abstract Session 

3:15 PM - 5:15 PM 

Room: 602-604 

867 3:15 PM 

Tumor Suppressor Properties of miR-122 and Its Biological 

Function in Mouse Liver 

Janaiah Kota, Shu-hao Hsu, Bo Wang, Huban Kutay, Stefan 

Costinean, Shoumei Bai, Lianbo Yu, Krista La Perle, Raghu R. 

Chivukula, K. Reed Clark, Samson T. Jacob, Jerry R. Mendell, 

Kalpana Ghoshal, Joshua T. Mendell. 

868 3:30 PM 

Encapsulated hESC Derived Islets as a Transplantation 

Therapy for Diabetes without Immunosuppression 

Kaitlyn Kirk, Ergeng Hao, Laura Martinson, Evert Kroon, 

Pamela Itkin-Ansari. 

869 3:45 PM 

Improved Retroviral Replicating Vectors for Prodrug- 

Activator Gene Therapy of Cancer 

Noriyuki Kasahara, Douglas J. Jolly, Daniel Pertschuk, 

Debra Gessner, Christopher Logg, Kei Hiraoka, Akihito 

Inagaki, Shuichi Kamijima, Ryan Burnett, Ching-I Chen, Pelle 

Pettersson, Derek Ostertag, Amy Lin, Walter Günzburg, Brian 

Salmons, Mitchel Berger,. 

870 4:00 PM 

CSF-Mediated Distribution of TPP1 from AAV Transduced 

Brain Ependyma Promotes Widespread Enzyme Activity in 

Nonhuman Primate Brain and Improves CNS Phenotypes in 

LINCL Dogs 

Martin L Katz, Luis Tecedor, Fred A Wininger, Joan R. Coates, 

Camille A. Flournoy, Katie Nice, Jeffrey Kordower, Beverly L 

Davidson. 

871 4:15 PM 

Gene Therapy Approach to Treat Osteoarthritis Using 

AAVIRAP 

LR Goodrich, CW McIlwraith, JN Phillips, SB Foti, RJ Samulski. 

872 4:30 PM 

Developing Photoreceptor Targeted AAV Varient by 

Directed Evolution 

D. Dalkara, R. Klimczak, M. Visel, D. Schaffer, J. Flannery. 

873 4:45 PM 

Postnatal Transplantation of FVIII-Expressing MSC 

Phenotypically Corrects Hemophilia A 

C. D. Porada, C. Sanda, C-J. Kuo, E. Colleti, R. Moot, C. Doering, 

H.T. Spencer, G. Almeida-Porada. 

874 5:00 PM 

Influence of Pre-Existing Neutralizing Antibodies on Gene 

Expression Following Intramuscular Administration of AAV 

Vectors 

Jenny A. Greig, Deirdre McMenamin, James M. Wilson. 


Abstract Directory Thursday, May 19, 2011 

PRESIDENTIAL SYMPOSIUM 200 

Presidential Symposium 

8:00 AM - 10:15 AM 

Room: 6BC 

49 8:45 AM 

In Vivo Delivery of Zinc Finger Nucleases Mediates Genome 

Editing To Correct Genetic Disease 

Michael Holmes, Hojun Li, Virginia Haurigot, Yannick Doyon, 

James Li, Anand Bhagwat, Sunnie Wong, Xavier Anguela, 

Rajiv Sharma, Sam Murphy, Fayaz Khazi, Shangzhen Zhou, 

David Paschon, Ed Rebar, Philip Gregory, Katherine High. 

50 9:05 AM 

Demonstration of Safety and Antitumoral Activity of JX- 

594, a Targeted Multi-Mechanistic Oncolytic Poxvirus, 

Following Intravenous Infusion and/or Intratumoral 

Injections in Patients with Refractory Metastatic Cancers 

Caroline Breitbach, James Burke, Anne Moon, Tae-Ho Hwang, 

John C. Bell, David H. Kirn. 

51 9:25 AM 

A Phase I Dose-Escalating Study of AAV1 – γ-Sarcoglycan 

Gene Therapy for Limb Girdle Muscular Dystrophy Type 2C 

Serge Herson, Fayçal Hentati, Aude Rigolet, Norma B. 

Romero, Anthony Behin, France Leturcq, Pascal Laforet, 

Thierry Maisonobe, Rim Amouri, Hafedh Haddad, Muriel 

Audit, Marie-Françoise Rosier-Montus, Bernard Gjata, Carole 

Masurier, François M. Lemoine, Pierre Carlier, Jean-Yves 

Hogrel, Bruno Eymard, Lee Sweeney, Richard Mulligan, David 

Klatzmann, Mustapha Cheraï, Didier Caizergues, Thomas Voït, 

Olivier Benveniste. 

52 9:45 AM 

Efficient Long-Term Bodywide Expression of an AAV9- 

Minidystrophin in the Muscle and Heart of Young Adult 

GRMD Dogs after Intravascular Injection without Immune 

Suppression 

Juan Li, Chunping Qiao, Janet Bogan, Dan Bogan, Ruhang 

Tang, JianBin Li, Chunlian Chen, Hui Zheng, Jennifer Dow, Joe 

N. Kornegay, Xiao Xiao. 


Adenovirus and Other DNA Virus Vectors II: 

Response to Vectors 

2:30 PM - 4:30 PM 

Room: 615-617 

53 2:30 PM 

An HSV Based Selection Method for Isolation of Negative 

Regulators of TRPV1 

Bonnie Reinhart, Asaff Harel, Justus B. Cohen, Joseph C. 

Glorioso. 

54 2:45 PM 

Interaction of Adenoviral Particles with Scavenger 

Receptors on Kupffer Cells Stimulates an Early, MyD88 

Dependent Innate Immune Response In Vivo 

Masataka Suzuki, Terry K. Bertin, Donna J. Palmer, Racel G. 

Cela, Margaretha Guenther, Ming-Ming Jiang, Kilian Guse, 

Phil Ng, Brendan H. I. Lee. 

55 3:00 PM 

Arming Adenovirus with CpG Motifs To Stimulate Innate 

and Adaptive Immune Response To Enhance Anti-Tumor 

Efficacy 

Vincenzo Cerullo, Valentina Romano, Iulia Diaconu, Matteo 

Ugolini, Noora Rouvinen-Lagerström, Akseli Hemminki. 

56 3:15 PM 

MicroRNA Control of HSV-1 Replication for the Treatment 

of Glioblastoma Multiforme 

Lucia Mazzacurati, Marco Marzulli, Bonnie Reinhart, Justus B. 

Cohen, Joseph C. Glorioso, Paola Grandi. 

57 3:30 PM 

High-Capacity Adenoviral Vectors Induce Multispecific CD8 

T Cell Responses and Show Improved Properties over 1st- 

Generation Vectors as Genetic Vaccines 

Matthias W. Kron, Tatjana Engler, Schmidt Erika, Reinhold 

Schirmbeck, Stefan Kochanek, Florian Kreppel. 

58 3:45 PM 

Oncolytic Adenovirus Expressing a Dual-Function Gene To 

Diagnose and Treat Pancreatic Cancer 

Julia Davydova, Miguel Trujillo, Samantha McDonough, 

Michael Oneal, Eric Brown, Joohee Han, Selwyn Vickers, John 

Morris, Masato Yamamoto. 

59 4:00 PM 

Gene Therapy-Mediated Delivery of Targeted Cytotoxins 

for Glioma Therapeutics: Efficacy in the Absence of 

Neurotoxicity 

Marianela Candolfi, Weidong Xiong, Kader Yagiz, Chunyan Liu, A. 

K. M. G. Muhammad, Mariana Puntel, David Foulad, Ali Zadmehr, 

Gabrielle Alzadeh, Kurt M. Kroeger, Matthew Tesarfreund, 

Sharon Lee, Waldemar Debinski, Dhruv Sareen, Clive Svendsen, 

Ron Rodriguez, Pedro R. Lowenstein, Maria G. Castro. 


Thursday, May 19


92 



Adenovirus and Other DNA Virus Vectors II: 

Response to Vectors 

2:30 PM - 4:30 PM 

Room: 615-617 

60 4:15 PM 

Kupffer Cell Evasion by a Hypervariable Region-Modified 

Adenovirus Vector 

Reeti Khare, Michael A. Barry. 



2:30 PM - 4:30 PM 

Room: 611-612 

61 2:30 PM 

Combinatorial Use of Block- and Homo-Polycation To Form 

DNA Polyplex Enhances Transgene Expressions in Mouse 

Lung with Minimal Toxicity 

Satoshi Uchida, Keiji Itaka, Qixian Chen, Kensuke Osada, 

Takehiko Ishii, Mariko Harada-Shiba, Masa-Aki Shibata, 

Kazunori Kataoka. 

62 2:45 PM 

Polymeric Delivery of siRNA for P-Glycoprotein Down- 

Regulation in a Xenograft Tumor Model in NOD-SCID Mice 

Meysam Abbasi, Hamid M. Aliabadi, Elaine Moase, Kamaljit 

Kaur, Charles Doillon, Raymond Lai, Afsaneh Lavasanifar, 

Hasan Uludag. 

63 3:00 PM 

Gene Therapy with Antibody Targeted Immunoliposome 

Rescue Experimental Parkinson’s Disease 

Qinghui Zhou, Ailing Fu, Boado Ruben, William M. Pardridge. 

64 3:15 PM 

Subcellular Trafficking and Transfection Efficacy of PEI-PEG 

Polyplex Nanoparticles with a Ligand to Melanocortin-1 

Receptors 

Alexey V. Ulasov, Yuri V. Khramtsov, Elena A. Beletkaia, Nikita 

S. Rodichenko, Georgiy A. Trusov, Mikhail O. Durymanov, 

Andrey A. Rosenkranz, Eugene D. Sverdlov, Alexander S. 

Sobolev. 

65 3:30 PM 

Cathepsin B-Labile Polymers for Endosome/Lysosome- 

Specific Degradation and Nucleic Acid Release 

David S. Chu, Russell N. Johnson, Suzie H. Pun. 

66 3:45 PM 

A Modified HK Carrier of siRNA Enhances Silencing of 

Tumor Targets In Vivo 

Szu-Ting Chou, Qixin Leng, Puthupparampil Scari, Archibald 

J. Mixson. 

67 4:00 PM 

Subcutaneous Delivery of Plasmid DNA to Hepatocytes by 

Ligand-Targeted Sub-50 nm Capsules 

B. T. Kren, V. L. Korman, D. Tolbot, G. M. Unger. 

68 4:15 PM 

Methods To Observe Intracellular Trafficking of Non-Viral 

Delivery Vehicles in 3D 

Nilesh P. Ingle, Theresa M. Reineke. 




2:30 PM - 4:30 PM 

Room: 618-620 

69 2:30 PM 

Exploring the Potential of Plasma Pheresis To Circumvent 

Pre-Existing Antibodies to AAV8 on Transgene Expression 

Following Targeted Vascular Delivery 

Louis G. Chicoine, Louise R. Rodino-Klapac, K. Reed Clark, 

Chrystal L. Montgomery, Thomas J. Preston, William G. 

Bremer, Katherine J. Campbell, Zarife Sahenk, Paul T. Martin, 

Christopher M. Walker, Jerry R. Mendell. 

70 2:45 PM 

Acceleration and Augmentation of Femoral Segmental 

Bone Healing by Adipose-Derived Stem Cells Engineered 

with Hybrid Baculovirus Vectors Conferring Sustained 

Transgene Expression 

Chin-Yu Lin, Kun-Ju Lin, Chun-Yu Kao, Tzu-Chen Yen, Yu-Han 

Chang, Yu-Chen Hu. 

71 3:00 PM 

Restoration of Dystrophin Expression in the mdx Mouse 

Model for Duchenne Muscular Dystrophy (DMD) Induced 

by RTC13 

Refik Kayali, Liutao Du, Jin-Mo Ku, Gladys Completo, Olga 

Prikhodko, Yosuf Subat, Hailiang Hu, Michael Jung, Richard A. 

Gatti, Carmen Bertoni. 

72 3:15 PM 

Effective Limb Transduction and Phenotypic Correction 

after Injection of rAAV8-U7 snRNA in GRMD Dogs 

Caroline Le Guiner, Marie Montus, Laurent Servais, Luis 

Garcia, Yves Fromes, Jean-Yves Hogrel, Pierre Carlier, Yan 

Cherel, Philippe Moullier, Thomas Voit, The AFM-Sponsored 

Duchenne Consortium. 

73 3:30 PM 

Inhibition of CD26 Activity Enhances Engraftment of Donor 

Cells to Regenerating and Dystrophic Skeletal Muscle 

Maura H. Parker, Carol Loretz, Rainer Storb, Stephen J. 

Tapscott.




2:30 PM - 4:30 PM 

Room: 618-620 

74 3:45 PM 

Addition of Peptide Therapy To Inhibit NF-κB Activation 

to AAV Serotype 9 Mini-Dystrophin Gene Transfer To Treat 

Muscular Dystrophy in mdx Mice 

Daniel P. Reay, Gabriela A. Niizawa, Jon F. Watchko, Molly 

Daood, Eugene Raggi, Paula R. Clemens. 

75 4:00 PM 

RNA Interference Improves Myopathic Phenotypes in Mice 

Over-Expressing Facioscapulohumeral Muscular Dystrophy 

Region Gene 1 (FRG1) 

Lindsay M. Wallace, Sara E. Garwick-Coppens, Scott Q. Harper. 

76 4:15 PM 

Sustained Expression of Canine Micro-Dystrophin and 

Amelioration of Muscle Function in Dystrophic Dogs 

Following Large Scale AAV-Mediated Treatment 

Zejing Wang, Rainer Storb, Donghoon Lee, Christine Halbert, 

Martine K. Childers, Glen Banks, James Allen, Eric Finn, Martin 

Kushmeric, Dusty Miller, Jeffery S. Chamberlain, Stephen J. 

Tapscott. 


Cancer Immunotherapy - Emphasis on 

Vaccines and Adjuvants 

2:30 PM - 4:30 PM 

Room: 6A 

77 2:30 PM 

Serial Treatment of Refractory Cancer Patients with GM-CSF 

Expressing Oncolytic Adenovirus Enhances Immunological 

Response and Survival without Compromising Safety 

Petri Nokisalmi, Anniina Koski, Anna Kanerva, Lotta 

Kangasniemi, Iulia Diaconu, Sari Pesonen, Vincenzo Cerullo, 

Timo Joensuu, Akseli Hemminki. 

78 2:45 PM 

Preclinical Efficacy and Safety Studies of a Monoclonal 

Antibody Co-Therapy for Cancer 

Roma Yumul, Hongjie Wang, Ines Beyer, Jonas Persson, Andre 

Lieber. 

79 3:00 PM 

Phase I Trial of Gene Mediated Cytotoxic Immunotherapy 

in Combination with Chemoradiation for Locally Advanced 

Pancreatic Cancer 

Mark Bloomston, Christopher Marsh, Jon Walker, Walter 

Coyle, Howard Marx, Sanaa Tahiri, Claudia Moran Cruz, Laura 

K. Aguilar, Estuardo Aguilar-Cordova, Vincent Chung. 

80 3:15 PM 

How To Improve Adoptive T Cell Immune-Gene Therapy: 

The Importance of Be(ginn)ing Naïve 

Nicoletta Cieri, Barbara Camisa, Elena Provasi, Zulma 

Magnani, Anna Mondino, Attilio Bondanza, Chiara Bonini. 

81 3:30 PM 

IL15-VAX: A Prostate Cancer Cellular Vaccine Expressing IL- 

15 and IL-15Ralpha 

Jason C. Steel, Charmaine A. Ramlogan, Ping Yu, Thomas A. 

Waldmann, John C. Morris. 

82 3:45 PM 

A Phase 1-2 Clinical Study of MGN1601, a Tumor Vaccine 

Comprising Allogeneic, Gene-Modified and Irradiated 

Tumor Cells in Combination with an Immunomodulator, in 

Patients with Metastatic Renal Cell Carcinoma (ASET Study) 

– Preliminary Results 

S. Weikert, M. Tschaika, E. Weith, V. Grünwald, M. Schroff, B. 

Wittig, M. Schmidt. 

83 4:00 PM 

DC-NILV: Dendritic Cell Targeting Non-Integrating 

Lentiviral Vector Platform for Direct Administration in 

Immunotherapeutic Clinical Settings 

N. Van Hoeven, J. Odegard, C. Nicolai, P. McGowan, M. 

Slough, D. Campbell, C. Vin, S. Tareen, S. Robbins, P. Wang, D. 

Baltimore, S. Reed, V. Slepushkin, T. Dubensky. 

84 4:15 PM 

T Cells Modified To Express Tumor Associated Antigens and 

Dendritic Cell-Activating Molecules for Cancer Vaccination 

Adham S. Bear, Meghan E. Turnis, Xiao-Tong Song, Conrad R. 

Cruz, An Lu, Gottschalk M. Stephen, Cliona M. Rooney, Aaron 

E. Foster. 


Small RNA and 

Oligonucleotide Based Therapeutics 

2:30 PM - 4:30 PM 

Room: 606-607 

85 2:30 PM 

Systemic Delivery of RNase H-Active Antisense Oligos in a 

Transgenic Mouse Model of Myotonic Dystrophy Type 1 

Thurman M. Wheeler, Andrew J. Leger, Sanjay K. Pandey, A. 

Robert MacLeod, Masayuki Nakamori, Seng H. Cheng, C. 

Frank Bennett, Bruce M. Wentworth, Charles A. Thornton. 

86 2:45 PM 

Role of Ago2 and microRNAs in Mammalian Development 

Paul N. Valdmanis, Hakkyun Kim, Yannick Pouliot, Mark A. Kay. 


Thursday, May 19


94 



Small RNA and 

Oligonucleotide Based Therapeutics 

2:30 PM - 4:30 PM 

Room: 606-607 

87 3:00 PM 

First Results of a Phase 2-3 Clinical Study with the 

Immunomodulator MGN1703 in Patients with Advanced 

Colorectal Carcinoma (IMPACT Study) 

M. Schmidt, H. J. Schmoll, F. Mayer, J. Riera-Knorrenschild, G. 

Hapke, B. Hildebrandt, W. Eisterer, J. Andel, R. Ziebermayr, E. 

Weith, M. Schroff, B. Wittig, M. Tschaika. 

88 3:15 PM 

ShRNA-Mediated Gene Silencing in Primetes with AAV8 

Takayuki Kubodera, Shinga Ohira, Yuko Katakai, Hiroaki 

Mizukami, Yukihiko Hirai, Michio Imamura, Kazuaki Chayama, 

Takashi Shimada, Keiya Ozawa, Hidehiro Mizusawa, Takanori 

Yokota. 

89 3:30 PM 

Dual Functional BAFF Receptor Aptamers Inhibit Ligand 

Induced Proliferation and Deliver siRNAs to NHL Cells 

Katrin Tiemann, Piotr Swiderski, Stephen Forman, John Rossi, 

Jiehua Zhou. 

90 3:45 PM 

Nanoparticle Delivery of PNA and Donor DNA for Genomic 

Modification and Inactivation of the CCR5 Gene 

Erica B. Schleifman, Nicole Ali McNeer, Andrew Jackson, Jean 

Leif, Christopher Cheng, Ranjit S. Bindra, Leonard D. Shultz, 

Dale L. Greiner, Priti Kumar, W. Mark Saltzman, Peter M. Glazer. 

91 4:00 PM 

In Vivo HIV Inhibition by CCR5 Knock-Down by RNA 

Interference through Stem Cell Based Gene Therapy 

Approach in the Humanized NSG BLT Mouse Model 

Saki Shimizu, Ruth Cortado, Emily Lowe, Anna Sahakyan, 

Joshua Boyer, Tom Suree, Dong Sung An. 

92 4:15 PM 

Efficient In Vivo Delivery of Vitamin E-Conjugated siRNA 

from Colorectum to Liver 

Kazutaka Nishina, Masahiro Murakami, Kie Yoshida, Hiroya 

Kuwahara, Hidehiro Mizusawa, Takanori Yokota. 




2:30 PM - 4:30 PM 

Room: 608-609 

93 2:30 PM 

Generation of Gene-Corrected, Vector- and 

Reprogramming Factor-Free iPS Cells from SCID-X1 

Patients 

Angelo Lombardo, Pietro Lo Riso, Bruno Di Stefano, Mario 

Amendola, Michael C. Holmes, Philip D. Gregory, Andrew R. 

Gennery, Vania Broccoli, Luigi Naldini. 

94 2:45 PM 

microRNA-126 Modulates the Sensitivity of Hematopoietic 

Stem and Progenitor Cells to Environmental Signals 

Bernhard Gentner, Alice Giustacchini, Francesco Boccalatte, 

Massimo Saini, Eric Lechman, John E. Dick, Luigi Naldini. 

95 3:00 PM 

Highly Efficient Hematopoietic Reconstitution by In Vivo 

Chemoselection of HPRT-Deficient Bone Marrow with 

6-Thioguanine 

Katrin Hacke, Akos Szakmary, Andrew R. Cuddihy, Janet A. 

Treger, Brooke T. Bogan, Nora Rozengurt, Nathan A. Lemp, Jiri 

Aubrecht, Gregory W. Lawson, Nagesh P. Rao, Gay M. Crooks, 

Robert H. Schiestl, Noriyuki Kasahara. 

96 3:15 PM 

Stem Cells Isolated from p65 Deficient Mice Improved the 

Histopathology of Skeletal Muscle in Dystrophic Mice 

Aiping Lu, Ying Tang, Minakshi Poddar, Bing Wang, Denis C. 

Guttridge, Paul D. Robbins, Johnny Huard. 

97 3:30 PM 

LYL1, a Basic Helix-Loop-Helix Transcription Factor, 

Promotes Hematopoietic Differentiation of Common 

Marmoset Embryonic Stem Cells 

Hirotaka Kawano, Tomotoshi Marumoto, Michiyo Okada, 

Tomoko Inoue, Takenobu Nii, Jiyuan Liao, Saori Yamaguchi, 

Yoko Nagai, Hiroyuki Inoue, Atsushi Takahashi, Erika Sasaki, 

Yoshie Miura, Kenzaburo Tani. 

98 3:45 PM 

Genome-Wide Definition of Transcriptionally Active 

Regulatory Elements in Human Stem Cells by Retroviral 

Scanning 

Valentina Poletti, Alessia Cavazza, Annarita Miccio, Danilo 

Pellin, Ermanno Rizzi, Giorgio Corti, Clelia Di Serio, Gianluca 

De Bellis, Fulvio Mavilio.




2:30 PM - 4:30 PM 

Room: 608-609 

99 4:00 PM 

Zinc Finger Nuclease Mediated Genomic Editing of CCR5 in 

Human Hematopoietic Stem Cells for Clinical Application in 

HIV Gene Therapy 

Lijing Li, Anitha Rao, Lan-Feng Cao, Kenneth Kim, Ursula 

Hofer, Paula Cannon, Philip D. Gregory, Michael C. Holmes, 

John Zaia, Qing Liu, John Rossi, David DiGiusto. 

100 4:15 PM 

Human Neural Stem Cells of Parthenogenetic Origin 

Ruslan Semechkin, Dmitry Isaev, Tatiana Abramihina, Nikolay 

Turovets, Richard A. West, Tatjana Zogovic-Kapsalis, Adnrey 

Semechkin. 



2:30 PM - 3:30 PM 

Room: 602-604 

101 2:30 PM 

Initial Results from a First-in-Man Study Delivering Non- 

Viral Gene Therapy JVS-100 To Treat Ischemic Heart Failure 

Marc S. Penn, Joseph Pastore, Rahul Aras, Didier Rouy, Gary 

Schaer, MaryJane Farr, Warren Sherman, Farrell Mendelsohn, 

Douglas Losordo. 

102 2:45 PM 

AAV8 Gene Therapy Leads to Significant Lowering 

of Plasma Cholesterol Levels in Humanized Mouse 

Models of Homozygous and Heterozygous Familial 

Hypercholesterolemia 

Sadik H. Kassim, Hui Li, Dawn Marchadier, Peter Bell, Scott 

Kobner, James M. Wilson, Daniel J. Rader. 

103 3:00 PM 

Phase I/IIa, Open-Labeled, Dose Escalation Clinical Study 

Using DVC1-0101 (F-Gene-Deleted Non-Transmissible 

Recombinant Sendai Virus Vector Expressing Human FGF- 

2) To Treat Peripheral Arterial Disease 

Yoshikazu Yonemitsu, Takuya Matsumoto, Hiroyuki Itoh, 

Jin Okazaki, Makiko Uchiyama, Kumi Yoshida, Toshihiro 

Onohara, Hiroyuki Inoguchi, Ryoichi Kyuragi, Atsushi Guntani, 

Mototsugu Shimokawa, Mitsuho Onimaru, Hiroshi Ban, 

Makoto Inoue, Tsugumine Zhu, Mamoru Hasegawa, Yoichi 

Nakanishi, Yoshihiko Maehara. 

104 3:15 PM 

Intrathoracic Administration of AAV9 Reverses Neural and 

Cardiorespiratory Dysfunction in Pompe Disease 

Darin J. Falk, Cathryn S. Mah, Meghan S. Soustek, Kun-Ze Lee, 

Denise A. Cloutier, Mai K. Elmallah, Kirsten E. Erger, Thomas J. 

Conlon, David D. Fuller, Barry J. Byrne. 


Lung and Respiratory Disease 


3:40 PM - 4:40 PM 

Room: 602-604 

105 3:40 PM 

Human Multipotent Stromal Cells Attenuate LPS-Induced 

Acute Lung Injury in Mice Via Secretion of TNF-alpha- 

Induced Protein 6 

Svitlana Danchuk, Joni H. Ylostalo, Fokhrul M. Hossain, Randy 

Sorge, Austin Ramsey, Joseph A. Laskey, Bruce A. Bunnell, 

David A. Welsh, Darwin J. Prockop, Deborah E. Sullivan. 

106 3:55 PM 

In Vivo Site-Specific Delivery of Nanoparticles to Airway 

Epithelium Monitored by Scintigraphy 

Maria Manunta, Robin McAnulty, Aristides Tagalakis, Amy 

McDowell, John Fleming, Livia Bolt, Lorenzo Biassoni, 

Cristopher O’Callaghan, Stephen Hart. 

107 4:10 PM 

Gene Transfer of the Epithelial Sodium Channel (ENaC) 

alpha1 Subunit Using Electroporation Protects from 

Lipopolysaccaride (LPS)-Induced Acute Lung Injury 

Xin Lin, David A. Dean. 

108 4:25 PM 

Self-Reactive T Cells to CFTR in Cystic Fibrosis (CF) and Non- 

CF Humans: Implications for Gene Therapy 

Maria P. Limberis, Roberto Calcedo, Uta Griesenback, Eric W. 

Alton, James M. Wilson. 

POSTER SESSION I 

4:40 PM - 6:40 PM 

Room: Hall 4B 


109 

DNA-Recognizing Integrase Fusion Protein Alters 

Integration Pattern of HIV-1 Based Vector 

Vesa Turkki, Diana Schenkwein, Mervi Ahlroth, Seppo 

Ylä-Herttuala. 


Thursday, May 19


96 


POSTER SESSION I — continued 

4:40 PM - 6:40 PM 

Room: Hall 4B 


110 

Development and Characterization of Targeted Lentiviral 

Vectors Pseudotyped with the Tupaia paramyxovirus 

Glycoproteins 

Theresa Enkirch, Sabrina Kneissl, Birgit Hoyler, Wolfgang 

Stremmel, Christian J. Buchholz, Christoph Springfeld. 

111 

Reliability Metrics for LM/LAM/nrLAM-PCR Coupled with 

High Throughput Sequencing 

Troy B. Hawkins, Aparna Jasti, Aaron Ernstberger, Keithanne 

Mockaitis, Kenneth Cornetta. 

112 

Assessing Potency in Lentiviral Vectors Pseudotyped with 

VSV-G, RD114 or FV Envelope Glycoproteins 

Anna C. Pulliam-Leath, Aparna Jasti, Helmut Hanenberg, Dirk 

Lindemann, Kenneth Cornetta. 

113 

Tracking Retroviral-Integrated Clones with Modified Non- 

Restriction Enzyme LAM-PCR Technology 

Chuanfeng Wu, Alexander Jares, Thomas Winkler, Jianjun Xie, 

Andre Larochelle, Cynthia E. Dunbar. 

114 

GP64 Pseudotyped Feline Immunodeficiency Virus-Based 

Vector Transduces Murine Primary Nasal Epithelial Cells 

with Greater Efficacy Than Primary Tracheal Epithelial Cells 

Mayumi Oakland, Paul B. McCray, Patrick L. Sinn. 

115 

Safety Evaluation of Gene Transfer Vectors for Gene 

Therapy of Wiskott-Aldrich Syndrome 

Yasuhiro Ikawa, Toru Uchiyama, Fabio Candotti. 

116 

Retrovirus with the Bioorthogonally Functionalized 

Envelope for Efficient, Convenient, and Versatile Labeling, 

Purification, and Targeted Delivery 

Shirley Wong, Haley Phan, Min Suk Shim, Young Jik Kwon. 

117 

Decitabine Effects on Lentiviral Transduction for Human 

CD34 + Cells 

Naoya Uchida, Matthew M. Hsieh, John F. Tisdale. 

118 

A New Lentiviral Based RNAi Platform Used in Gene 

Validation in Tuberculosis Research and Effects of 

Modifications in the Transgene 3’ UTR 

Ulrike Jung, Kellen C. Fae, Juan P. Patron, John J. Rossi, Stefan 

H. E. Kaufmann. 

119 

Reducing Immune Response to Lentiviral Vectors by the 

Display of Human Self’ Marker, CD47 on Vector Envelope 

Nisha Sosale, Richard K. Tsai, Irena Ivanovska, Philip W. 

Zoltick, Dennis E. Discher. 



120 

Hepatocellular Carcinoma Due to Targeted Promoter 

Insertion by AAV Vectors 

Mei Xu, Peirong Wang, Yi Li, David W. Russell. 

121 

Regulation of AAV Mediated Transgene Expression by a 

Host Cell Transcriptional Repressor PARP-1 

Sangeetha Hareendran, Nishanth Gabriel, Arun Srivastava, 

Alok Srivastava, Giridhara Rao Jayandharan. 

122 

AAV-Mediated Gene Delivery and Gene Targeting in 

Human Embryonic Stem Cells 

Prashanth Asuri, Melissa A. Bartel, Jae-Hyung Jang, David V. 

Schaffer. 

123 

Absence of Integration Hotspots in Mice after 

Intramuscular Injection of AAV1-LPL S447X 

C. Kaeppel, S. Beattie, A. Nowrouzi, U. Appelt, R. Kirsten, H. 

Glimm, J. Snapper, C. von Kalle, H. Petry, M. Schmidt. 

124 

Adeno-Associated Viral Vector DNA Is Insensitive to De 

Novo CpG Methylation but Rapidly Associates with Histone 

Modifications in Liver and Skeletal Muscle 

Adrien Léger, Caroline Le Guiner, Michael L. Nickerson, 

Nicolas Ferry, Philippe Moullier, Richard O. Snyder, Magalie 

Penaud-Budloo. 

125 

AAV-Mediated Gene Correction for the Treatment of 

Recessive Dystrophic Epidermolysis Bullosa 

Rowan Flynn, Lisa M. Petek, Andrew P. South, Daniel G. Miller. 

126 

A Distinctive Fate of rAAV Vector Genomes in the Liver 

Transduced with Very Low Doses of rAAV8 in Mice 

Kei Adachi, Hiroyuki Nakai.



4:40 PM - 6:40 PM 

Room: Hall 4B 


127 

AAV-Mediated shRNA Integration into an Endogenous 

miRNA Locus as a New Strategy for Safe, Specific and 

Persistent Therapeutic RNAi 

Stefan Mockenhaupt, Dirk Grimm. 

128 

Naturally Occurring Non-Functional Mutations of the AAV 

ITR 

Cameron Mroske, Hector Rivera, Taihra Ul-Hassan, Saswati 

Chatterjee, K. K. Wong, Jr. 

129 

Establishment and Use of a Configuration-Specific Method 

To Determine the Structure of AAV-ITRs Recombined by 

DNA Repair Pathways 

Baocheng Huang, Hiroyuki Nakai. 

130 

AAV Vectors Copurify with Microvesicles in Producer 

Cell Media: Implications for Gene Transfer and Vector 

Purification 

Casey A. Maguire, Leonora Balaj, Sara Sivaraman, Johan 

Skog, Miguel Sena-Esteves, Xandra O. Breakefield, Bakhos A. 

Tannous. 

131 

A Simple Strategy To Increase the Transduction Efficiency 

of Single-Stranded AAV Vectors In Vitro and In Vivo 

Wenqin Ma, Baozheng Li, Chen Ling, Giridhara R. 

Jayandharan, Arun Srivastava, Barry J. Byrne. 

132 

Site-Specific Modification of AAV2 Vector by Using the 

Genetically Encoded Aldehyde Tag 

Yarong Liu, Kye-Il Joo, Pin Wang. 

133 

Construction of (Multi) Monomeric Duplex Adeno- 

Associated Vectors for Human Gene Therapy 

Jacek Lubelski, Yvet Noordman, Bas Bosma, Larbi Afia, Harald 

Petry, Andrew Bakker. 

134 

Targeted Integration of an rAAV Vector into the AAVS1 Site: 

Measurement of the Integration Rate without Selection 

Peter Ward, Christopher E. Walsh. 


135 

Microscopy Analysis of Adenovirus Serotype 3 Interaction 

with its Receptor Desmoglein 2 

Zong-Yi Li, Hongjie Wang, Ines Beyer, Pascal Fender, Andre 

Lieber. 

136 

The Role of Endosomal Escape and Mitogen Activated 

Protein Kinases in Adenoviral Activation of the Innate 

Immune Response 

Jeffrey S. Smith, Zhili Xu, Jie Tian, Donna J. Palmer, Philip Ng, 

Andrew P. Byrnes. 

137 

The Sequential Proteolysis and Liberation of the 

Intracellular Domain of CD44 Modulates Adenoviral Vector 

Transgene Expression and Replication of Adenovirus 

Wesley S. Bond, Cristhian J. Ildefonso, Mary Y. Hurwitz, 

Richard L. Hurwitz. 

138 

Enhanced Transduction of Fiber Modified Ad in Canine 

Lymphoma Cell Lines 

Ann Marie O’Neill, David T. Curiel, Bruce F. Smith. 

139 

Simultaneous Genetic Peptide Targeting of Adenovirus 

Subtype 5 towards Two Different Receptors 

Michael Behr, Maximilian Richter, Martin A. Häusl, Philipp 

Fieger, Sarah Engelhardt, Carolin Stegmüller, Alexander H. 

Enk, Anja Ehrhardt, Dirk M. Nettelbeck. 

140 

Augmentation of Rat Skin Flap Viability by Relaxin- 

Expressing Adenovirus 

Il-Kyu Choi, Won Jai Lee, In Sik Yun, Yong-Oock Kim, Tae Jin 

Yun, Dong Kyun Rah, Chae-Ok Yun. 

141 

A Rapid, PCR-Based Method for Direct In-Vitro Cloning into 

Recombinant Adenoviral Vectors 

Thomas P. Quinn, Lily Lee, Mei Fong, Michael Haugwitz, 

Hiroaki Sagawa. 

142 

Differential Effects of Murine and Human Factor X on 

Adenovirus Transduction Via Cell Surface Heparan Sulfate 

Anne K. Zaiss, Roger Lawrence, David Elashoff, Jeffrey D. Esko, 

Harvey R. Herschman. 

143 

Improved Tropism of Adenoviral Vectors for Muscle Cells 

Using an IGF-1R Targeted Bispecific Ligand 

Maxime Pinard, Birgit Kastberger, Yue Zeng, Nancy Larochelle, 

Josephine Nalbantoglu, Bernard Massie, Rénald Gilbert. 


Thursday, May 19


98 



4:40 PM - 6:40 PM 

Room: Hall 4B 


144 

An Alternate Method for Efficient Delivery of Catalyzing 

Enzymes 

Andrew D. Fontes, Rene Quintanilla, Michael Poderycki, Jon 

Chesnut, Uma Lakshmipathy. 

145 

A Hypoxia and α-Fetoprotein-Dependent Oncolytic 

Adenovirus Exhibits Specific Killing of Hepatocellular 

Carcinomas 

Oh-Joon Kwon, Pyung-Hwan Kim, Steven Huyn, Lily Wu, 

Minjung Kim, Chae-Ok Yun. 

146 

Quantification of Wild Type Replicative Adenovirus 

Contamination That Results from Amplification of 

Conditionally Replicative Adenovirus 

Eric J. Brown, Julia Davydova, Masato Yamamoto, Selwyn M. 

Vickers. 

147 

Specific Modification of Hexon with 5KDa PEG Improves 

the Therapeutic Index of Helper-Dependent Ad Vector for 

Liver-Directed Gene Therapy 

Francesco Vetrini, Donna J. Palmer, Nathan C. Grove, Amanda 

Rosewell, Florian Kreppel, Philip Ng. 

148 

Multi-Modal Imaging Reveals Sites of Cellular 

Reprogramming in Treatment of Type-1 Diabetes 

Neil Phillips, Mark Kay. 


149 

T1α Promoter-Mediated Gene Delivery into Alveolar 

Epithelial Type I Cells 

Lynn F. Gottfried, David A. Dean. 

150 

New Gene Regulation Delivery System Using Peptide- 

Pendant Polyethyleneimine for Cancer Cell-Specific 

Therapy and Imaging 

Yoshiki Katayama, Riki Toita, Leong-Hun Kang, Takeshi Mori, 

Takuro Niidome. 

151 

Gene Delivery to Oral Cancer Cells by Transferrin- 

Polyplexes and Tat-Peptide-Lipoplexes 

Senait Gebremedhin, Stephen Koons, Krystyna Konopka, 

Nejat Duzgunes. 

152 

Highly Effective Non-Viral Antitumor Gene Therapy 

System Comprising Biocompatible Small Plasmid Complex 

Particles 

Chieko Yoshihara, Tomoko Ito, Yoshiyuki Koyama. 

153 

Characterization of Lipoplex Properties and Gene Transfer 

Efficiency of a Novel Family of Cationic Carotenoid Lipids 

Natalia Bilchuk, Matthew S. Adams, Rachel Jones, Alexandra 

M. Liberski, Christer L. Øpstad, Vassilia Partali, Hans-Richard 

Sliwka, Howard H. Lou, Michael D. Pungente, Philip L. 

Leopold. 

154 

Preparation of Hydroxyapatite Nanocapsule Including 

DNA/PEI/Hyaluronic Acid Ternary Complex for Durable 

Gene Delivery 

Tomoko Ito, Makoto Otsuka. 

155 

Lipopolymer Mediated siRNA Delivery Strategy for Acute 

Myeloid Leukemia Cells 

Breanne Landry, Hamidreza Montazeri Aliabadi, Hasan 

Uludag. 

156 

Development of Nanocomplexes for Targeted siRNA Delivery 

Aristides D. Tagalakis, Luisa Saraiva, Stephen L. Hart. 

157 

Designing DNA-Doped Biomineral Nanocomposites for 

Effective and Safe Gene Delivery 

Bingbing Sun, Hong Shen. 

158 

Tumor-Directed Small Interfering RNA Delivery by Anti- 

EGFR Immunonanoplexes 

Jung Seol Kim, Yeon Kyung Lee, Hwa Yeon Jeong, Young Eun 

Shin, Keun Sik Kim, Yong Serk Park. 

159 

Reducible Poly(Amido Ethyleneimine)s Affect Cellular 

Redox Potentials through Copper Mediated Enzymes 

James W. Yockman, Young Won Lee, Jonathan H. Brumbach, 

Katherine S. Blevins, Zachary J. Robbins, Sung Wan Kim. 

160 

EGFR-Mediated Gene Delivery Using Anti-EGFR 

Immunonanoparticles 

Jung Seok Kim, Yeon Kyung Lee, Wha Yeon Jeong, Young Eun 

Shin, Keun Sik Kim, Yong Serk Park. 

161 

Bioreducible Polymer Conjugated Cell Penetrating 

Peptides for siRNA Delivery 

Hye Yeong Nam, Sung Wan Kim, David A. Bull. 




4:40 PM - 6:40 PM 

Room: Hall 4B 


162 

Polymeric Delivery of a Bone Morphogenetic Protein-2 

Plasmid at Rat Subcutaneous Site 

Laura Rose, Cezary Kucharski, Hasan Uludag. 

163 

Developing Magnetic Nanoparticles for Targeted Nucleic 

Acid Delivery and Detection 

Andrew M. Prantner, Jun Chen, Christopher B. Murray, 

Nathalie Scholler. 

164 

Acid-Transforming Polypeptide for Efficient, Targeted, and 

Molecularly Tunable Nonviral Gene Delivery 

Min Suk Shim, Young Jik Kwon. 

165 

The Nuclear Pore Dilating Agent TCHD Increases Gene 

Transfer into Differentiated Airway Epithelium Ex Vivo, But 

Has No Effect In Vivo 

Uta Griesenbach, Katherine M. Wilson, Raymond Farley, 

Cuixiang Meng, Ronald K. Scheule, Seng H. Cheng, Eric W. F. 

W. Alton. 

166 

Stimuli-Sensitive Copolymer Nanocapsules for Nontoxic 

and Efficient Non-Viral Gene Delivery 

Min Sang Lee, Yeon Lim Jang, Myung Goo Kim, Dai Phu 

Huynh, Cong Truc Huynh, Yuhan Lee, Su Young Chae, Sun 

Hwa Kim, Tae Gwan Park, Doo Sung Lee, Ji Hoon Jeong. 

167 

Non-Viral Gene Delivery with 25-kD PEI and G4 PAMAM 

Are Dependent on Active Clathrin and Caveolar Trafficking 

Pathways 

Mark E. Hwang, Rahul K. Keswani, Daniel W. Pack. 

168 

RhoGTPases Modulate Non-Viral Gene Delivery 

Anandika Dhaliwal, Maricela Maldonado, Clayton Lin, Tatiana 

Segura. 

169 

Tailorable PNA-Based siRNA Nanoconjugates for Cell- 

Responsive Gene Silencing 

Abbygail A. Palmer, Millicent O. Sullivan. 

170 

Disrupted Adenovirus-Based Nicotine Conjugate Vaccine 

To Treat Nicotine Addiction 

Bishnu P. De, Martin L. Hicks, Jonathan B. Rosenberg, Amira Y. 

Moreno, Kim Janda, Stephen M. Kaminsky, Ronald G. Crystal. 

171 

Transfection of Cells by RGD-Tagged PEGylated Lipid-DNA 

Nanoparticles in Serum 

Chia-Ling Chan, Ramsey N. Majzoub, Kai K. Ewert, Keng-San 

Liang, Cyrus R. Safinya. 

172 

A “Soft Polyplex” of Oligoarginine-Grafted Polymers 

Affording a Protein Kinase-Responsive Gene Expression 

Takeshi Mori, Hiroyuki Tanaka, Riki Toita, Takuro Niidome, 

Yoshiki Katayama. 

173 

Directed Movement and Velocity of Transfected Plasmids Is 

Enhanced on Acetylated Microtubules 

Melissa A. Badding, David A. Dean. 

174 

Quantification of Intracellular Polyplex Distribution Via 

Subcellular Fractionation Techniques 

Julie Shi, Brian Chou, David Chu, Russell N. Johnson, Suzie H. 

Pun. 

175 

Histone-Mimetic Polyplexes as Self-Activating and 

Tailorable Non-Viral Gene Delivery Vehicles 

Meghan J. Reilly, Millicent O. Sullivan. 

914 (MOVED FROM POSTER SESSION III) 

Intracellular Trafficking of a Histone-Mimetic Polyplex to 

Promote Nucleus-Specific Self-Unpackaging 

Meghan J. Reilly, John D. Larsen, Millicent O. Sullivan. 

176 

Oligonucleotide-Conjugated Silver Nanoparticles for 

Photoactivated Gene Silencing 

Paige K. Brown, Ammar T. Qureshi, Alyson L. Moll, Daniel J. 

Hayes, W. Todd Monroe. 

177 

Development of Peptide-Based HPMA-Copolymers for 

Nucleic Acid Delivery 

Russell N. Johnson, Dave Chu, Julie Shi, Suzie H. Pun. 

178 

Multifunctional Nanocarriers for Enhancing Suicide Gene 

Therapy 

Jiesheng Wang, Jen-I. Hsu, Ching-An Peng. 

179 

Enhanced Stability and Knockdown Efficiency of 

Poly(ethylene Glycol)-b-Polyphosphoramidate/siRNA 

Micellar Nanoparticles by Co-Condensation with Sodium 

Triphosphate 

Masataka Nakanishi, Rajesh Patil, Yong Ren, Hai-Quan Mao. 


Thursday, May 19


100 



4:40 PM - 6:40 PM 

Room: Hall 4B 


180 

Aromatic Self-Assembling Polyethylenimines Are 

Efficacious siRNA Delivery Reagents 

Guy Zuber, Benoit Frisch, Gaelle Creusat. 

181 

Liver Targeted siRNA Delivery by Different Polymeric 

Carriers Containing Monosaccharide or Polysaccharide 

Tetsuji Yamaoka, Wakako Kamata, Yoichi Tachibana, Mariko 

Harada-Shiba, Jeong-hun Kang. 

182 

Cutaneous Gene Delivery Using Pyrene-Substituted 

Gemini-Lipid Nanoparticles 

Mahmoud Elsabahy, Ildiko Badea, Ronald Verrall, Marianna 

Foldvari. 



183 

Improved Chylomicron Clearance as a Marker for Long- 

Term Efficacy of Alipogene Tiparvovec (AAV1-LPL S447X Gene 

Therapy) in LPLD Patients 

Jaap Twisk, Frederique Frisch, Stephen Greentree, Harald 

Petry, Janneke de Wal, Diane Brisson, Claude Gagné, André C. 

Carpentier, Daniel Gaudet. 

184 

Pharmacological Immunosuppression Fails To Improve the 

Outcome of AAV-Based Liver Gene Transfer in Non-Human 

Primates 

Carmen Unzu, Sandra Hervas-Stubbs, Ana Sampedro, Itsaso 

Mauleon, Uxua Mancheño, Carlos Alfaro, Rafael Enriquez 

de Salamanca, Alberto Benito, Ignacio Melero, Antonio 

Fontanellas. 

185 

Pre-Existing Neutralizing Antibodies to AAV Capsids in 

Large Animals Other Than Monkeys May Confound In Vivo 

Gene Therapy Studies 

Roberto Calcedo, Judith Franco, Qiuyue Qin, Dean W. 

Richardson, Jeffrey B. Mason, Surina Boyd, James M. Wilson. 

186 

Impact of Pre-Existing Neutralizing Antibodies on AAV8- 

Mediated, Liver-Directed Gene Transfer and Vector 

Biodistribution in Nonhuman Primates 

Lili Wang, Roberto Calcedo, Peter Bell, Jianping Lin, Rebecca 

Grant, Don L. Siegel, James M. Wilson. 

187 

Comprehensive Integration Site Analysis of One New Gene 

Therapy Vector AAV-rDNA 

Zhongya Wang, Hiroyuki Nakai, Markus Grompe. 

188 

Relationship between Neutralizing Antibody and Factor 

IX Expression in Non-Human Primates Following IV 

Administration of AAV8 Vectors 

Hiroaki Mizukami, Jun Mimuro, Akira Ishiwata, Hiroya Yagi, 

Tsukasa Ohmori, Seiji Madoiwa, Tomonori Tsukahara, Masashi 

Urabe, Akihiro Kume, Yoichi Sakata, Keiya Ozawa. 

189 

Development of a Clinical HIV-Based SIN Vector Encoding a 

High-Expression Factor VIII Transgene for the Treatment of 

Hemophilia A 

Christopher B. Doering, Gabriela Denning, Robert Moot, 

Jennifer Johnston, Jordan Shields, Boro Dropulic, H. Trent 

Spencer. 

190 

Gene and Cell Therapy for Hemophilia B Using Adipose 

Tissue-Derived Stem/Stromal Cells Transduced with a Self- 

Inactivating SIV Lentivirus Vector 

Natsumi Watanabe, Kazuo Ohashi, Kohei Tatsumi, Rie Utoh, 

Kazuko Kanegae, Yuji Kashiwakura, Tsukasa Ohmori, Yoichi 

Sakata, Makoto Inoue, Mamoru Hasegawa, Teruo Okano. 

191 

Optimizing Engraftment of FANCA Gene-Modified Bone 

Marrow Cells in a Mouse Model of Fanconi’s Anemia 

Jennifer E. Adair, Xin Zhao, Pamela S. Becker, Hans-Peter 

Kiem. 

192 

Mozobil-Alone or Mozobil+G-CSF Significantly Improve the 

Mobilization Efficiency of Thalassemic Mice: Implications 

for Human Gene Therapy of Thalassemia 

Evangelia Yannaki, Nikoleta Psatha, Eleni Sgouramali, 

Evangelia Athanasiou, Eleftheria Tsolaki, Minas 

Yiangou, Minas Arsenakis, Athanasios Fassas, Achilles 

Anagnostopoulos. 

193 

AAV Mediated Liver-Specific Gene Therapy for Thrombotic 

Thrombocytopenic Purpura (TTP) in a Murine Model 

Sheng-Yu Jin, Juan Xiao, Fraser J. Wright, X. Long Zheng. 

464 MOVED FROM POSTER SESSION II 

Hematopoietic Differentiation of Airway Epithelial Cell-Derived 

Cystic Fibrosis (CF) Induced Pluripotent Stem (iPS) Cells 

R. Geoffrey Sargent, Yanu Yang, Albert Lee, Marcus O. 

Muench, Soya Kim, Arash Bedayat, Layli Jamali, Lin Ye, Judy 

Chang, Dieter C. Gruenert. 




4:40 PM - 6:40 PM 

Room: Hall 4B 



712 MOVED FROM POSTER SESSION III 

Hematopoietic Stem Cell Gene Therapy with a Lentiviral 

Vector for the Multi-Systemic Lysosomal Storage Disorder 

Cystinosis 

Frank Harrison, Brian A. Yeagy, Donald B. Kohn, Daniel R. 

Salomon, Stephanie Cherqui. 

Neurologic & Ophthalmic Gene & Cell Therapy I 

194 

Long-Term Phenotypic Correction of Feline Lysosomal 

Storage Disease by Intracranial AAV Gene Therapy 

Victoria J. Jones, Allison M. Bradbury, Misako Hwang, Stanley 

G. Leroy, Stacy Maitland, Aime K. Johnson, Miguel Sena- 

Esteves, Douglas R. Martin. 

195 

Brain Gene Therapy for Metachromatic Leukodystrophy: 

Optimized Clinical Protocol 

Caroline Sevin, Françoise Piguet, Dolan Sondhi, Marie-Anne 

Colle, Thomas Roujeau, Sylvie Raoul, Jack-Yves Deschamps, 

Celine Bouquet, Ornella Ahouansou, Marie Vanier, Philippe 

Moullier, Yan Cherel, Neil R. Hackett, Michel Zerah, Ronald G. 

Crystal, Patrick Aubourg, Nathalie Cartier. 

196 

Dosage Thresholds and Vector Serotype Define AAV 

Targeting of Rod and Cone Photoreceptors in Non-Human 

Primates 

Luk H. Vandenberghe, Peter Bell, Albert M. Maguire, Ru Xiao, 

Rebecca Grant, Jean Bennett, James M. Wilson. 

197 ABSTRACT WITHDRAWN 

198 

RNAi Therapy for Spinocerebellar Ataxia Type 1 

Megan K. Keiser, Ryan L. Boudreau, Beverly L. Davidson. 

199 

Long-Term Persistence of AAV Mediated Gene Therapy for 

Leber Congenital Amaurosis Type 1 (LCA1) 

Sanford L. Boye, Thomas Conlon, Kirsten Erger, Travis 

Cossette, Jijing Pang, Sukanya Karan, Renee Ryals, Wolfgang 

Baehr, William W. Hauswirth, Shannon E. Boye. 

200 

Correction of the Lysosomal Storage Defect in Mouse 

Model of Juvenile Neuronal Ceroid Lipofuscinosis by 

Neonatal Injection of AAV Serotype rh.10 Vector Expressing 

the Human CLN3 Gene 

Dolan Sondhi, Neil R. Hackett, Emma Scott, Alvin Chen, Susan 

Cotman, Ronald G. Crystal. 

201 

The Effect of Pre-Existing Immunity to AAV on CNS 

Directed Gene Therapy 

Christopher M. Treleaven, Thomas J. Tamsett, Jonathan 

A. Fidler, Gregory D. Hurbult, Seng H. Cheng, Lamya S. 

Shihabuddin, James C. Dodge. 

202 

Microglia as an Attractive Cellular Vehicle for Gene Therapy 

of Parkinson’s Disease 

K. C. Biju, Rene A. Santacruz, Cang Chen, Robert A. Clark, 

Senlin Li. 

203 

Early Functional and Long-Term Rescue of the LHON Mouse 

with Wild-Type Human ND4 Gene Delivery 

Rajeshwari D. Koilkonda, Tsung-Han Chou, Marco Ruggeri, 

Vittorio Porciatti, William W. Hauswirth, Vince Chiodo, Sanford 

L. Boye, John Guy. 

204 

Adeno-Associated Virus Mediated Gene Therapy for 

Treatment of Autosomal Dominant Retinitis Pigmentosa 

(ADRP) 

Haoyu Mao, Marina S. Gorbatyuk, William W. Hauswirth, 

Alfred S. Lewin. 

205 

CNS Expression of Glucocerebrosidase Corrects 

Hippocampal alpha-Synuclein Aggregates and 

Memory Deficits in a Mouse Model of Gaucher-Related 

Parkinsonism 

Pablo S. Sardi, Lamya S. Shihabuddin, Seng H. Cheng. 

206 

Anterograde Trafficking of AAV2 Vectors in the Primate 

Brain 

Adrian P. Kells, Ernesto Aguilar Salegio, Krystof S. Bankiewicz. 

207 

Evaluation of the Immune Responses in the Treatment 

of RPE65 Deficient Dogs by Subretinal Injection of a 

Recombinant AAV Serotype 4 

Nathalie Provost, Lise Libleau, Alexandra Mendes Madeira, 

Jack-Yves Deschamps, Michel Weber, Guylène LeMeur, 

Yan Cherel, Philippe Moullier, Fabienne Rolling, Christine 

Chauveau. 


Thursday, May 19


102 



4:40 PM - 6:40 PM 

Room: Hall 4B 

Infectious Diseases and Vaccines I 

208 

Inhibition of Human Immunodeficiency Virus (HIV) Type 1 

Replication through Expression of RNAi Effectors Targeting 

HIV-Dependency Factor HTATSF1 

Victoria Green, Patrick Arbuthnot, Marco S. Weinberg. 

209 

Protection Against Divergent Influenza H1N1 Virus by a 

Centralized Influenza Hemagglutinin 

Eric A. Weaver, Richard Webby, Michael A. Barry. 

210 

Administration of AdC7-OprF Expressing the P. aeruginosa 

Protein OprF and Carrying the RGD Sequence in the Fiber 

Provides Longterm Mucosal Immunity without Increasing 

Cellular Immunity 

Anja Krause, Wen Zhu, Yaqin Xu, Ronald G. Crystal, Stefan 

Worgall. 

211 

Combination of CCR5delta32 and shRNAs Targeting HIV 

Ekta Patel, Starlyn Okada, Yingchi Chen, Miao-Fen Chao, 

Qingwen Jin, Li-Min Huang, Ghalib Alkhatib, Lung-Ji Chang. 

212 

Post-Exposure Treatment with a Human Adenovirus 

5 Vector-Based Combination Therapy Against Zaire 

Ebolavirus and Avian Influenza H5N1 in Small Animals 

Ami Patel, Jason Richardson, Jane Ennis, Jeff Turner, Gary P. 

Kobinger. 

213 

Lentivector Expressing HBsAg and Immunoglobulin Fc 

Fusion Antigen Induces Potent Immune Responses and 

Results in Seroconversion in HBsAg Transgenic Mice 

Yuan Hong, Yibing Peng, Michael Mi, David H. Munn, Guiqiang 

Wang, Yukai He. 

214 

Passive Immunization Strategy for Pandemic Influenza 

Using AAV Delivery of Broadly-Neutralizing Antibodies 

Virginie S. Adam, James M. Wilson, Maria P. Limberis. 

215 

Strategies for Therapeutic Vaccination: Electroporation- 

Mediated Delivery of DNA Vaccines in the Woodchuck 

Hepatitis Model 

Claire F. Evans, Katherine H. Liu, Mary A. Ascenzi, Christine A. 

Bellezza, Abraham J. Bezuidenhout, Alain Luxembourg, Drew 

W. Hannaman, Paul J. Cote, Bud C. Tennant, Stephan Menne. 

216 

Porcine Adenovirus 3 or Human Adenovirus 5 Vectors 

Expressing HA and NP Does Not Improve Cross-Clade 

Protection Against Avian Influenza H5N1 

Ami Patel, Suresh K. Tikoo, Yan Li, Gary P. Kobinger. 

217 

HIV Latency: Overcoming Transcriptional Block (Initiation 

and Elongation) 

Suresh K. Arya. 

218 

Production and Characterization of Monoclonal Antibodies 

Against Brucella melitensis Bp26 for Mapping the Antigenic 

Epitope 

Jinlang Qiu, Wenjing Wang, Hui Zhang, Yuanzhi Wang, Ling 

Zhang, Yixin Bian, Hongwei Li, Chuangfu Chen, Chengyao Li. 

219 

GLA Synergize with Dendritic Cell-Directed LV for an 

Improved Immune Response 

Liang Xiao, Matt Lin, Jocelyn Kim, Lili Yang, Pin Wang. 



220 

Chemotherapy in Combination with T-Cell Therapy Results 

in Significant Antitumor Activity and Improved Clinical 

Outcomes for EBV-Associated Nasopharyngeal Carcinoma 

Marissa Teo, John Chia, Peter Wang, David Tai, Joanna Ng, 

ChitLai Chee, Fei Gao, SzeHuey Tan, SooFan Ang, Yatanar Soe, 

Stephen Gottschalk, HanChong Toh. 

221 

A Novel Single Chain Chimeric Antigen Receptor 

Framework Provides Tumor Reactivity of Retrovirally 

Transduced Human T Cells towards an erbB2 + Breast 

Carcinoma Cell Line 

Ralf-Holger Voss, Winfried S. Wels, Matthias Theobald. 

222 

GM-CSF Gene Transduced Murine Cancer Stem Cells 

Eliminate Tumorigenicity In Vivo 

Chika Sakamoto, Hiroyuki Inoue, Yusuke Murakami, Yosuke 

Yokota, Megumi Narusawa, Shohei Miyamoto, Ayumi 

Watanabe, Makoto Inoue, Koichi Takayama, Mamoru 

Hasegawa, Yoichi Nakanishi, Kenzaburo Tani. 

223 

Estimation of T Cell Receptor (TCR) Diversity by Next 

Generation Sequencing Technologies 

Eliana Ruggiero, Ali Nowrouzi, Anne Arens, Hanno Glimm, 

Manfred Schmidt, Christof von Kalle.



4:40 PM - 6:40 PM 

Room: Hall 4B 


224 

Targeting B-Cell Malignancies with Chimeric Antigen 

Receptor-Modified γδ T Cells 

Drew C. Deniger, Harjeet Singh, Helen Huls, Simon Olivares, 


225 

Adoptive Transfer Therapy Using Expanded Melanoma- 

Specific T Cells Programmed Ex Vivo for Improved Efficacy 

In Vivo 

Helen A. Andersson, Jessica A. Hernandez, Sourindra Maiti, 

Helen Huls, Laszlo Radvanyi, Laurence J. N. Cooper. 

226 

Intratumoral Expression of CTLA4 Monoclonal Antibody 

Induces Immunosuppressive NKT Cells in a Mouse Model of 

Breast Cancer with Tolerance to Her2/neu 

Jonas Persson, Ying Liu, Roma Yumul, Ines Beyer, Hans-Peter 

Kiem, Steve Roffler, Andre Lieber. 

227 

Efficient Eradication of Castration-Resistant Human 

Prostate Cancers by Inactivated Sendai Virus Particle 

Koji Hatano, Yoshifumi Kawaguchi, Yasuhide Miyamoto, Norio 

Nonomura, Yasufumi Kaneda. 

228 

Development of a T Cell Receptor Targeting the 

HLA-A*0201 Restricted Epitope SSX2: 41-49 for Adoptive 

Immunotherapy of Cancer 

Nachimuthu Chinnasamy, Jeremy L. Davis, Mahadev Rao, 

David S. Schrump, Daniel E. Speiser, Steven A. Rosenberg, 

Richard A. Morgan. 

229 

Apoptosis Inducer ABT-737 Enhances Efficacy of 

Engineered CD19-Targeting T-Cells 

Hannah Karlsson, Camilla Lindqvist, Gabriella Paul- 

Wetterberg, Per Frisk, Angelica Loskog. 

230 

Validation of Donor Derived Virus Specific T-Lymphocytes 

Genetically Modified To Target the CD19 Antigen for the 

Treatment of Relapsed Leukemia 

Kevin J. Curran, Clare Taylor, Ekaterina Doubrovina, Xiuyan 

Wang, Richard J. O’Reilly, Michel Sadelain, Nancy A. Kernan, 

Renier J. Brentjens, Isabelle Riviere. 

231 

Development of Genetically Engineered T Cells Expressing 

a Chimeric Antigen Receptor Against Prostate Stem Cell 

Antigen for the Adoptive Cell Therapy of Cancer 

Kiran H. Lagisetty, William R. Burns, Zheng Zhili, Steven A. 

Rosenberg, Richard A. Morgan. 

232 

Delivery of Dendritic Cells Engineered To Express T-bet into 

Solid Murine Tumors Defines an Effective Therapy 

Jennifer L. Taylor, Yanyan Qu, Lu Chen, Walter J. Storkus. 

233 

Comparative Microarray Analysis Implicates the Pivotal 

Participation of Type I Interferon Related Signaling 

Pathway in Antitumor Effect Provoked by In Vivo GM-CSF 

Gene Transduced Lung Cancer Cells 

Megumi Narusawa, Hiroyuki Inoue, Yoshihiro Tanaka, Yosuke 

Yokota, Chika Sakamoto, Shohei Miyamoto, Tomoko Inoue, 

Makoto Inoue, Koichi Takayama, Mamoru Hasegawa, Yoichi 

Nakanishi, Kenzaburo Tani. 

234 

T Cells Genetically Modified To Express Chimeric Antigen 

Receptor Specific for EGFR for Glioma 

Hillary G. Caruso, Sonny Ang, Singh S. Harjeet, Simon 

Olivares, Laurence J. N. Cooper. 

235 

In Vivo Delivery of Interferon-alpha Gene Enhances 

Tumor Immunity and Suppresses Immunotolerance after 

Autologous Hematopoietic Stem Cell Transplantation 

Kenta Narumi, Takeshi Udagawa, Yoshinori Ikarashi, Takahiro 

Ochiya, Teruhiko Yoshida, Kazunori Aoki. 

236 

Induction of Epitope-Specific CD8+ T Cells for Melanoma 

Eradication by Intratumoral Electroportation of IL-12 cDNA: 

A Possible Mechanism for Tumor Killing 

Jeong-Im Sin. 

237 

Oncolytic Plasmid System, a Novel Antitumor Strategy by 

Plasmid Encoding Adenovirus Protein 

Yoshiyuki Koyama, Chieko Yoshihara, Masahiko Tojyo, 

Tomoko Ito, Katsuyuki Hamada. 


238 

Therapeutic Efficacy and Safety Studies of a Novel 

Oncolytic Adenovirus Active in Tumor-Associated Stromal 

Cells and Tumor Microenvironment 

Diego L. Viale, Veronica M. Lopez, Eduardo G. Cafferata, 

David Gould, Yuti Chernajovsky, David T. Curiel, Osvaldo L. 

Podhajcer. 


Thursday, May 19


104 



4:40 PM - 6:40 PM 

Room: Hall 4B 


239 

Expansion and Anti-Tumor Efficacy of CD19 Targeted Cord 

Blood T Cells 

Hollie J. Pegram, Vincent La Russa, Renier J. Brentjens. 

240 

Expression of Membrane Bound GD2 Peptide Mimic on 

K562 Cell Line Supports Antigen Specific Expansion of T 

Cells Modified with GD2 Chimeric Antigen Receptor 

Srinivas S. Somanchi, Laurence J. N Cooper, Dean A. Lee. 

241 

Identification of Targeted Adenovirus Vector for Pancreatic 

Cancer by Screening Large Adenoviral Library with 

Random AB-Loop-Mutations 

Yoshiaki Miura, Eric Brown, Julia Davydova, Masato Yamamoto. 

242 

Insulin-Like Growth Factor Binding Protein 7 (IGFBP7): A 

Novel Therapeutic for Hepatocellular Carcinoma 

Dong Chen, Byoung Kwon Yoo, Prasanna K. Santhekadur, 

Rachel Gredler, Paul B. Fisher, Devanand Sarkar. 

243 

Uterine Fibroids Gene Therapy: Targeted Adenovirus 

Vector (Ad-SSTR-RGD-TK/GCV) Provides Superior Inhibition 

of Human Leiomyoma Cells than Human Uterine Smooth 

Muscle Cells 

Sangeeta Nair, David T. Curiel, Ayman Al-Hendy. 

244 

Telomerase Inhibition Strategies by siRNAs Against Either 

hTR or hTERT in Oral Squamous Cell Carcinoma 

Yan Li, Liying Xiao, Mingyuan Li, Gang Yao, Yun Feng. 

245 

Functional Characterization of TCRP1, a Novel Gene 

Mediating Resistance to Cispltin in Oral Squamous Cell 

Carcinoma Cell Line 

Yixue Gu, Shasha Fan, Yang Xiong, Bo Peng, Guopei Zheng, 

Zhimin He. 

246 

Aerosol Delivery of Small Hairpin Osteopontin Blocks 

Pulmonary Metastasis of Breast Cancer in Mice 

Kyeong-Nam Yu, Myung-Haing Cho. 

247 

A Fusion Protein, Tat-CYGB, Is a Potential Agent for Liver 

Cancer Therapy 

Ruian Xu, Weijie Shi, Weidong Xiao. 

248 

Transcriptional Targeting of Retrovirus Vector through the 

SSX4 Tumor-Specific Promoter 

Toshio Yawata, Eri Ishida, Masahiro Kitahara, Keiji Shimizu. 

249 

Establishment of Transgenic Mice Expressing a Biotin Binding 

Targeting Construct on the Endothelium of Blood Vessels 

Thomas Wirth, Anke Nicolaus, Georg Breier, Seppo 





250 

MGMT P140K and TK HSV Chemoselection of Allogeneic 

HSC and Correction of β-Thalassemia after Neonatal 

Transplantation without Myeloablation or Post-Transplant 

Immunosuppression 

Rustom Falahati, Jianqing Zhang, Yimin Shi, Linda Flebbe- 

Rehwaldt, Stanton L. Gerson, Karin M. L. Gaensler. 

251 

Pharmacologically Regulated Cell Growth of Specific 

Hematopoietic Lineages 

David W. Emery, Brandon Thomas, Kiyoshi Okazuka, Emilie A. 

Lovelett, Brian C. Beard, Hans-Peter Kiem, C. Anthony Blau. 

252 

Towards Lentiviral IL2RG Gene Therapy for SCID-X1: The 

Importance of Pre-Transplant Conditioning and Cell Dose 

Marshall W. Huston, Niek P. van Til, Trudi P. Visser, Helen de 

Boer, Gerard Wagemaker. 

253 

A2UCOE-eGFP Confers Sustained Transgene Expression in 

Human Fetal Liver Hematopoietic Stem Cells (FL-HSC) 

Niraja Dighe, Maroun Khoury, Mark Chong, Citra Mattar, 

Simon Waddington, Michael N. Antoniou, Jianzhu Chen, 

Mahesh Choolani, Jerry Chan. 

254 

Correction of RAG2 Severe Combined Immunodeficiency 

by Lentiviral Gene Therapy Requires Strong Expression of 

RAG2 

Niek P. van Til, Helen de Boer, Roya Sarwari, Trudi P. Visser, 

Barbara Cassani, Anna Villa, Gerard Wagemaker. 

255 

Correction of X-SCID by Sleeping Beauty-Mediated Gene 

Transfer into Hematopoietic Cells 

Kendra A. Hyland, Erik R. Olson, Nicola Philpott, Xianzheng 

Zhou, R. Scott McIvor.



4:40 PM - 6:40 PM 

Room: Hall 4B 



256 

The Comparison of Various Promoters for Wiskott Aldrich 

Syndrome Gene Therapy Using Insulated Lentiviral Vectors 

Rachel M. Koldej, Gael Carney, Matthew Wielgosz, 

Satyanarayana Pondugula, Arthur W. Nienhuis. 

257 

In Vivo, Lineage-Directed Transgene Expression after 

Hematopoietic Stem Cell Gene Transfer in a Large Animal 

Model 

Aravind Ramakrishnan, Beverly Torok-Stord, Mortimer Poncz, 

Nathaniel P. Williams, Christina Ironside, Hans-Peter Kiem, 

Brian C. Beard. 

258 

Non-Myeloablative Conditioning with Busulfex 8 mg/kg 

or 200 cGy TBI Is Equivalent in Gene Therapy of Canine 

Leukocyte Adhesion Deficiency Using Foamy Viral Vectors 

Thomas R. Bauer, Jr., Erik M. Olson, Laura M. Tuschong, Tanya 

H. Burkholder, David W. Russell, Dennis D. Hickstein. 

259 

Mouse Transplant Models for Evaluating the Safety of a 

SCID-X1 Lentiviral Vector 

Sheng Zhou, Zhijun Ma, Taihe Lu, Laura J. Janke, John T. Gray, 

Brian P. Sorrentino. 

260 

Balancing Efficacy and Adverse Outcomes in Gene Therapy 

for Wiskott-Aldrich Syndrome 

Alexander Astrakhan, Blythe Sather, Sara Mamman, Michelle 

Brault, Socheath Khim, Byoung Ryu, Carol Miao, David J. 

Rawlings. 

261 

Further Amelioration of the Late Effects of Total 

Body Irradiation (TBI) by Manganesium Superoxide 

Dismutase Plasmid/Liposome (MnSOD-PL) Gene 

Therapy Supplemented by a Continuous Antioxidant- 

Chemopreventive Diet 

Michael W. Epperly, Hong Wang, Jeffrey A. Jones, Tracy Dixon, 

Carlos A. Montesinos, Joel S. Greenberger. 

262 

High Levels of Polyclonal, Multilineage Hematopoietic 

Cell Gene Marking Following Lentiviral Transduction and 

Transplantation of Steady-State Bone Marrow CD34 + Cells 

in a Non-Human Primate Model 

Phillip W. Hargrove, Yoon-Sang Kim, Amy Taylor, Dana 

Simpson, Andrew M. Davidoff, Perdeep K. Mehta, Derek A. 

Persons. 

263 

Long-Term Multi-Lineage Engraftment of NOD-scid 

IL2Rgnull Mice after Transplantation with Genetically 

Modified b-thalassemic CD34 + Cells 

Leda Ferro, Jinrong Qu, Clare Taylor, Xiuyan Wang, Aurelio 

Maggio, Farid Boulad, Sadelain Michel, Isabelle Riviere. 

264 

Uncovering Haemopoietic System Dynamics and Tracking 

Fate and Long-Term Survival of Single Progenitor Clones In 

Vivo in Humans by Retroviral Tagging 

Luca Biasco, Cristina Baricordi, Cynthia Bartholomae, 

Immacolata Brigida, Samantha Scaramuzza, Raffaele Fronza, 

Stefania Merella, Alessandro Ambrosi, Danilo Pellina, Clelia Di 

Serio, Eugenio Montini, Christof von Kalle, Manfred Schmidt, 

Alessandro Aiuti. 

265 

Deep Sequencing Analyses of Small RNAs in HIV-1 Infected 

Cells Transduced with a Triple Inhibitory RNA Lentiviral 

Vector 

Haitang Li, John Rossi. 

266 

Decade-Long Persistence of Adoptively Transferred 

Autologous Redirected CD4ζ Chimeric Receptor T Cells in 

HIV+ Study Subjects 

John Scholler, Naomi Aaronson, Gabriela Plesa, Richard 

Carroll, Gwendolyn Binder, Kristen Hege, Steven Deeks, 

Ronald Mitsuyasu, Ashley Vogel, Zhaohui Zheng, Julio Cotte, 

Wendy Bernstein, Troy Brady, Bruce Levine, Carl June. 

267 

Development of a New Strategy for X-CGD Gene Therapy 

Using a miRNA Regulated Lentiviral Vector 

Maria Chiriaco, Giada Farinelli, Bernhard Gentner, Gigliola 

Di Matteo, Valentina Capo, Silvia Di Cesare, Samantha 

Scaramuzza, Lucia Sergi Sergi, Antonella Isgrò, Didier Trono, 

Manuel Grez, Andrea Finocchi, Paolo Rossi, Luigi Naldini, 

Alessandro Aiuti. 

268 

Correction of Mouse Prkdc scid Deficiency by ZFN-Driven 

Gene Repair 

Hayder H. Abdul-Razak, Céline Rocca, Francisco Javier Molina 

Estévez, Guillermo Güenechea, Steven J. Howe, Chih Hao V. 

Gan, Alison Roberts, Michael C. Holmes, Philip D. Gregory, 

Adrian J. Thrasher, Juan A. Bueren, Rafael J. Yáñez-Muñoz. 


Thursday, May 19


106 



4:40 PM - 6:40 PM 

Room: Hall 4B 



269 

Safety and Clonality Analyses for a New Vector for CGD 

Clinical Gene Therapy 

Simone Scholz, Margarita Diaz, Stefan Stein, Axel Schambach, 

Hanno Glimm, Christof von Kalle, Manuel Grez, Manfred 

Schmidt. 


BAFF Inhibition by Exon Skipping in Sjögren’s Syndrome 

Nienke Roescher, Jelle Vosters, Ghada Al Saleh, Patrick 

Dreyfus, Sebastien Jacques, Luis Garcia, Gilles Chiocchia, 

Antoine Francoise, Jean Sibilia, Paul Peter Tak, Jay Chiorini, 

Xavier Mariette, Jacques-Eric Gottenberg. 

Lung and Respiratory Disease 


270 

Adeno-Associated Virus Transduction in the Ferret Airway 

Ziying Yan, Diana C. M. Lei-Butters, Xingshen Sun, Xiaoming 

Liu, Nicholas W. Keiser, John Fisher, Hongshu Sui, John F. 

Engelhardt. 

271 

The Airway Epithelium Differentiation State Affects 

Efficiency of siRNA Oligonucleotide Delivery 

Sateesh Krishnamurthy, Ashley Jacobi, Scott D. Rose, Mark A. 

Behlke, Paul B. McCray, Jr., Beverely L. Davidson. 

272 

Strain-Specific Differences in Pulmonary Gene Transfer 

Efficiency: Relevance for Toxicology Studies in Mice 

Giannoulis Legakis, Benjamin Causton, Jie Zhu, Nikki 

Newman, Raymond Farley, Cuixiang Meng, Clare M. Lloyd, 

Eric W. F. W. Alton, Uta Griesenbach. 

273 

Reporter Gene Expression Following Repeat 

Administration of a HIV-1 Lentiviral Vector in Mouse 

Airways 

Patricia L. Cmielewski, Don S. Anson, David W. Parsons. 

274 

Gene Transfer by Influenza HA Pseudotyped EIAV Lentiviral 

Vectors to the Airways of Neonatal Mice 

Manij Patel, John C. Olsen. 

275 

Generation of Inducible CFTR-Expressing Lentiviral Vectors 

for Gene Therapy 

Xiaoming Liu, Meihui Luo, Yulong Zhang, John F. Engelhardt. 

276 

The Therapeutic Role of TSLP shRNA in Treating Pulmonary 

Fibrosis 

Guo-Zheng Liu, Tsung-Jen Hung, Su-Fen Liu, Tao-Chen Lee, 

Zih-Han Yang, Lea-Yea Chuang, Jinn-Yuh Guh, Tung-Nan Liao, 

Min-Yuan Hung, Yu-Lin Yang. 

277 

Efficient Transduction of Alveolar Type II Epithelial Cells 

in Nonhuman Primates by Helper-Dependent Adenovirus 

5-Fiber 35 Chimeric Vectors 

Amanda Rosewell, Peter Hiatt, Ruth McConnell, Dianne 

Dang, Francesco Vetrini, Nathan Grove, Donna Palmer, Milton 

Finegold, Arthur Beaudet, Philip Ng. 

278 

Delivery Dynamics and Destination of Gene Vector 

Instillations in Live Mouse Airways 

Martin W. Donnelley, Karen K. W. Siu, R. Aidan Jamison, David 

W. Parsons. 

279 

Lung Epithelial Binding Peptide-Linked High Mobility 

Group Box-1 A Box as a Lung Epithelial Cell Targeting Gene 

Carrier 

Hyun Ah Kim, Su Hee Cho, Ji Hwan Park, Minhyung Lee. 

280 

Development of a Nonviral Gene Therapy Approach for 

Surfactant Protein B Deficiency 

Rebecca C. Barnett, David A. Dean. 

281 

One Year Persistence from a Single HIV-1 Lentiviral Vector 

Delivery into Marmoset Lung: LacZ and Vector Gene 

Presence 

David W. Parsons, Nigel Farrow, Darren Miller, Shannon Le 

Blanc, Richard Bright, Don S. Anson. 

282 

E1B-55kDa Deleted Adenoviruses Induce p53 Up- 

Regulation Resulting in Apoptosis in Human Malignant 

Mesothelioma 

Yuji Tada, Makako Yamanaka, Kiyoko Kawamura, Shinya 

Okamoto, Shan Yang, Atsushi Kitamura, Suguru Yamauchi, 

Liang Min, Hiroshi Kobayashi, Yuichi Takiguchi, Koichiro 

Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa. 




4:40 PM - 6:40 PM 

Room: Hall 4B 

Immunologic & Host Responses in 


283 

dAd5GNE300, a 2nd Generation Anti-Cocaine Adenovirus- 

Based Vaccine That Blocks Cocaine-Induced Activity, 

Reward and Drug Seeking in Rodents 

Jonathan B. Rosenberg, Sunmee Wee, Martin L. Hicks, Bishnu 

P. De, Stephen M. Kaminsky, Amira Y. Moreno, Kim Janda, 

George Koob, Ronald G. Crystal. 

284 

Lmo2 Over-Expression and p19 Arf Loss Genetically 

Cooperate To Increase the Self-Renewal Capacity of 

Immature Thymocytes 

Louise M. Treanor, Sheng Zhou, Taihe Lu, Brian P. Sorrentino. 

285 

Sequential Gene Therapy with Aumentation of Expression 

Is Possible with Neonatal Gene Transfer 

Chuhong Hu, Eun K. Lee, Gerald S. Lipshutz. 

286 

Live Oral Bacterial Cell Therapy for Term Infants with 

Cyanotic Congenital Heart Malformations: Investigating 

Hypoxia and Probiotic Induced Changes in the Intestinal 

Microbiota 

Collin L. Ellis, John C. Rutledge, Gary W. Raff, Mark A. 

Underwood. 

287 

Liver-Specific Expression of the Insulin Epitope 9-23 Using 

a Lenti-Viral, microRNA142 Regulated Vector Protects 

Against Autoimmune Diabetes 

Akbarpour Mahzad, Kevin Goudy, Naldini Luigi, Maria-Grazia 

Roncarolo. 

288 

The AAV2(Y-F) Mutant Capsid Causes Immune Avoidance 

to Killing by Capsid Specific CD8+ T Cells and Is Further 

Improved by Proteasome Inhibition 

Ashley T. Martino, David M. Markusic, Arun Srivastava, Roland 

W. Herzog. 

289 

Differential Activation of Innate Immune Responses and 

T Cell Proliferation by Adeno-Associated Virus Vectors 

Containing Different Regulatory Cassettes in Murine 

Pompe Disease 

Ping Zhang, Takuya Osada, Andy Bird, Songtao Li, Timonthy 

Clay, Dwight Koeberl. 

290 

FoxP3-Treg Preconditioning with IL-2-IL-2 Antibody 

Complex Overcomes Promotes Transgene Tolerance in a 

Stringent Autoimmune Model after Lenti-Viral Transfer 

Kevin Goudy, Mahzad Akabarpur, Andrea Annoni, Luigi 

Naldini, Maria-Grazia Roncarolo. 

291 

The Critical Role of Activation Induced Cell Death and 

Passive Apoptosis in the Induction of In Vivo Tolerance 

toward AAV8 in the Liver 

Susan M. Faust, Tullia Lindstein, Craig B. Thompson, James M. 

Wilson. 

292 

Direct Presentation, Not Cross Presentation of AAV Capsids, 

Render Hepatocytes Target for CTLs in a Humanized Mouse 

Model 

Suryanarayan Somanathan, Luk Vandenberghe, Peter Bell, 

Soumitra Roy, James L. Riley, James M. Wilson. 

293 

Adaptive Immunity to rAAV1 Is Supported by Capsid- 

Specific Th1 T Cell Responses and Is Critically-Dependent 

upon MyD88 Signaling in B Cells 

Muriel Sudres, Séverine Ciré, Virginie Vasseur, Léa Bréaut, 

Sylvie Darocha, Florence Boisgérault, Christine LeBec, David- 

Alexandre Gross, Bernard Ryffel, Anne Galy. 

294 

Development of Novel Strategies To Modulate Pre-Existing 

Anti-Factor VIII Immune Responses in Hemophilia A 

Inhibitor Mice Treated with Factor VIII Plasmid-Mediated 

Gene Therapy 

Chao-Lien Liu, Peiqing Ye, Jacqueline Lin, Carol H. Miao. 

295 

Upregulation of Interferon Pathways in Tumors Resistant to 

Oncolytic Adenovirus 

Ilkka Liikanen, Vladia Monsurrò, Laura Ahtiainen, Mari Raki, 

Tanja Hakkarainen, Iulia Diaconu, João D. Dias, Vincenzo 

Cerullo, Anna Kanerva, Sari Pesonen, Daniela Marzioni, Marco 

Colombatti, Akseli Hemminki. 

296 

TLR9 Signaling and Regulatory T-Cells Orchestrate the 

Immune Response to the Transgene Product in Muscle 

Brad E. Hoffman, Mario Cooper, Roland W. Herzog. 

297 

Activities of Nucleic Acid Binding and Stimulation of ATP 

Hydrolysis by RNA Helicase RIG-I and Activation of Type I 

Interferon Response 

Sujin Yoon, Kyung-Bo Kim, Kkothanahreum Park, Keun-Sik 

Kim, Dong-Eun Kim. 


Thursday, May 19


108 



4:40 PM - 6:40 PM 

Room: Hall 4B 

Gene Regulation I 

298 

Integration of Lentiviral Vectors in Human Genes Generates 

Abnormal Transcripts through the Usage of Constitutive 

and Cryptic Splice Signals 

Arianna Moiani, Riccardo Mezzadra, Daniela Sartori, Ylenia 

Paleari, Annarita Miccio, Fabienne Cocchiarella, Claudia 

Cattoglio, Giuliana Ferrari, Fulvio Mavilio. 

299 

The RNA Interference Pathway Is Responsible for Silencing 

of Transgene Expression after Sleeping Beauty Mediated 

Somatic Integration 

Christina Rauschhuber, Anja Ehrhardt. 

300 

Further Improvements and Applications of Context- 

Dependent Assembly (CoDA): A Publicly Available, 

Selection-Free Method for Engineering Zinc Finger 

Nucleases 

Jeffry D. Sander, Deepak Reyon, Ryan Kuzmickas, Cyd Khayter, 

Morgan L. Maeder, J. Keith Joung. 

301 

Direct Regulation of GDNF Protein Stability Using 

Destabilizing Domains 

Luis Quintino, Khalid Tai, Christina Isaksson, Tom Wandless, 

Cecilia Lundberg. 

302 

Interaction between LCR and a Replicator Mediated by the 

LARC Complex Prevents Methylation-Dependent Gene 

Silencing 

Liang Huang, Haiqing Fu, Chii Mei Lin, Mirit I. Aladjem. 

303 

Multimodal Targeted In Vivo Imaging of Brain Tumors 

Johanna M. Niers, Mariam Kerami, John W. Chen, Ralph 

Weissleder, Bakhos A. Tannous. 

304 

Regulation of B23/Nucleophosmin Protein Expression and 

Function by HIV-1 Derived miR-TAR-5p and miR-TAR-3p 

Dominique L. Ouellet, John J. Rossi, Patrick Provost. 

305 

Scavenging in Reactive Oxygen Species Improves Gene 

Expression in Polyplex Supported Gene Delivery: Nitroxyl- 

Radical Containing Nanoparticles Assists Non-Viral Gene 

Delivery System 

Yukio Nagasaki, Kazuko Toh, Toru Yoshitomi, Yutaka Ikeda. 

306 

Gaussia Luciferase: A Biomarker for In Vivo Evaluation of 

Systemic Protein Delivery through Circulation 

Salim S. El-Amouri, Phoung Cao, Dao Pan. 

307 

Multimodal In Vivo Imaging and Blood Monitoring of 

Intrinsic and Extrinsic Apoptosis 

Johanna M. Niers, Mariam Kerami, Lisa Pike, Grant 

Lewandrowski, Bakhos A. Tannous. 

308 

Prolonged Gene Silencing Effect Using Multilayered siRNA 

Coated Gold Nanoparticles 

Seung-Koo Lee, Myung-Shin Han, Ching-Hsuan Tung. 

309 

Implication of nNOSμ Delocalization on the Muscle Force in 

Dystrophin Deficient and δ-Sarcoglycan Knockout Mice 

Dejia Li, Yongping Yue, Yi Lai, Chady H. Hakin, Dongsheng 

Duan. 



310 

Human Hematopoietic Stem Cells Can Be Functionally 

Isolated Based on Their Low Intracellular Reactive Oxygen 

Species (ROS) Activity 

Brian Ichwan, Cynthia E. Dunbar, Andre Larochelle. 

311 

Differentiation of Diabetic Patient-Specific iPS Cells into 

Insulin-Secreting Cells 

Tayaramma Thatava, Karen Squillace, Adam Armstrong, Seiga 

Ohmine, Yogish Kudva, Yasuhiro Ikeda. 

312 

Overexpression of CXCR4 in Purified Hematopoietic Stem 

Cells Led to Poor Peripheral Reconstitution with Impaired 

Marrow Release of Progenitor Cells: Implications in Clinical 

Transplantation 

Chen Yi Lai, Sachie Suzuki, Motohito Okabe, Satoshi 

Yamazaki, Masafumi Onodera, Makoto Otsu, Hiromitsu 

Nakauchi. 

313 

Knockdown of p21 Cip1/Waf1 Enhances Proliferation, the 

Expression of Stemness Markers and Osteogenic Potential 

in Human Mesenchymal Stem Cells 

Tu-Lai Yew, Chih-Chien Tsai, Fang-Yao Chiu, Shih-Chieh Hung. 

314 

Pre-Clinical Evaluation of Zinc Finger Nuclease-Modified 

Mobilized Hematopoietic Stem Cells in NSG Mice 

Ursula Hofer, Jill E. Henley, Kathrin A. Burke, Nathalia Holt, 

Lijing Li, David L. DiGiusto, John A. Zaia, Philip D. Gregory, 

Michael C. Holmes, Paula M. Cannon.



4:40 PM - 6:40 PM 

Room: Hall 4B 

315 

Establishment of Human iPS Cell Lines Heterozygous for 

Genes in the Non-Homologous End-Joining Pathway by 

Using Helper-Dependent Adenoviral Vectors 

Keiichiro Suzuki, Yuka Hirabayashi, Emi Aizawa, Yuzuru 

Iwanaga, Ayako Tokumitsu, Ko Mitani. 

316 

Combination Sox Transcription Factor and Tgf-Beta Gene 

Transduction Drive Pre-Transplant Chondrogenesis in 

Adult Marrow Derived Stromal Cells 

Alan J. Nixon, Jan-Jan Liu, Michael S. Scimeca, Ashlee E. Watts. 

317 

Generation of Induced Pluripotent Stem (iPS) Cells Using 

Helper-Dependent Adenoviral Vectors 

Nunzia Pastore, Rosa Maria Sepe, Pasquale Piccolo, Donna 

Palmer, Philip Ng, Nicola Brunetti-Pierri. 

318 

Cationic-Liposome-Mediated CXCR4 Gene Delivery into 

Hematopoietic Stem/Progenitor Cells: Implications for 

Clinical Transplantation 

Peng Xu, Jie Chen, James Xing, Hilal Gul. 

319 

Development of Polyamidoamine Dendrimer-Conjugated 

Quantum Dots for Tracing Primary Cultured Mesenchymal 

Stem Cells in Mice 

Yuriko Higuchi, Wu Can, Shigeru Kawakami, Fumiyoshi 

Yamashita, Mitsuru Hashida. 



321 

Generation of Insulin-Producing Cells from PDX-1 Gene- 

Modified Human Umbilical Cord Mesenchymal Stem Cells 

Dongmei He, Juan Wang, Yangjun Gao. 

322 

New Adipose Tissue Formation by Human Adipose-Derived 

Stem Cell with Hyaluronic Acid Gel 

Shu Hung Huang, Sheng Hua Wu, Sin Daw Lin, Chung Sheng 

Lai. 

323 

Mobilization and Enrichment of Mesenchymal Stem Cells 

In Vivo Augments Bone Healing in a Mouse Model of 

Segmental Bone Defect 

Sanjay Kumar, Selvarangan Ponnazhagan. 

324 

Fully Pluripotent Patient-Specific Induced Pluripotent 

Stem (iPS) Cells and In Vivo Converted Cells: The Transient 

Epigenetic Gene Therapy Approach 

Roger Bertolotti. 

325 

Benefits of Hypoxic Culture on Bone Marrow-Derived 

Mesenchymal Stem Cells 

Shih-Chieh Hung, Chih-Chien Tsai. 


875 

Human Papillomavirus Pseudoviruses as Gene Delivery 

Vectors for Murine and Human Tumors 

Rebecca J Cerio, Jeffrey N Roberts, Cynthia D Thompson, 

Douglas R Lowy, John T Schiller. 

876 

A New Surface Modified Lentivector Targets Gene Transfer 

Ex Vivo into hHSC in Marrow from Patients with BM Failure 

Syndrome and In Vivo in Humanized Mice 

François-Loïc Cosset, Cecilia Frecha, Caroline Costa, Didier 

Nègre, Fouzia Amirache, Didier Trono, Juan Bueren, Els 

Verhoeyen. 

877 

Role of Immune Response and Immune Tolerization in 

Long-Term In Vivo Gene Expression Mediated by the 

Sleeping Beauty Transposon System 

Kelly M Podetz-Pedersen, Stephen J Russell, David B 

Schowalter, Nikunj V Somia, R Scott McIvor. 

878 

In Vivo Targeting of microRNA 21 Using Lentiviral Vectors 

for the Gene Therapy of Pancreatic Cancer 

Flavie Sicard, Hubert Lulka, Louis Buscail, Pierre Cordelier. 

879 

Regulation of Endogenous GAD67 Expression Using 

Artificial Transcription Factors. 

Erika Elgstrand Wettergren, Fredrik Gussing, Maike Sest, 

Torbjörn Gräslund, Cecilia Lundberg. 

880 

Intracarotid Injection of Adipose Tissue-Derived PDGFRβ+ 

Cells Rescues Ischemic Brain with Neuro-Vasculogenic 

Potential 

Kon Chu, Keun-Hwa Jung, Soon-Tae Lee, Sang Kun Lee, Jae- 

Kyu Roh. 

881 

Effective and Safe Gene-Based Delivery of GLP-1 Using 

Chitosan/Plasmid-DNA Therapeutic Nanocomplexes in an 

Animal Model of Type 2 Diabetes 

M. Jean, M. Alameh, V. Daras, M. Lavertu, M. Thibault, M.D. 

Buschmann, A. Merzouki. 


Thursday, May 19


110 



4:40 PM - 6:40 PM 

Room: Hall 4B 


882 

Tight Regulation of Transgene Expression by Mifepristone- 

Inducible System after In Vitro Delivery by Lentiviral Vectors 

to Neural Progenitor Cells 

Christopher Grunseich, Yijun Shi, Kenneth H. Fischbeck, Tyler 

M. Pierson. 

883 

Rheoswitch-Mediated Regulation of IL-12 Protein Delivered 

Using an Adenoviral Vector Results in Anti-Tumor Effects 

Across a Spectrum of Tumor Types 

Selva Murugesan, Mario Moreno, Sheila Connelly, Fayaz 

Khazi, Meixia Bi, Mini Bharathan, Charles Reed, Mark 

Thornton, Sunil Chada. 

884 

Knockdown of ENaCα as a Treatment for Cystic Fibrosis 

Lung Disease 

Rebekka E. Harding-Smith, Deborah R. Gill, Stephen C. Hyde. 

885 

Synergistic Effect of a Novel Gene Therapeutic Agent, VB- 

111, with Chemotherapy, for Treatment of Cancer 

Eyal Breitbart, Yael C. Cohen, Livnat Bangio. 

886 

Ad-Egr1-Luc Adenoviral Vector is Functionally Activated by 

UV Light 

Francisco Martínez-F, Araceli Barrera-L, Christian Y Lomeli-R, 

JA Madinaveitia-V, Erendira Estrada-V, Hugo Sandoval-Z, 

Hilda Villegas-C, Catalina Machuca-R, David T. Curiel, K 

Sakamoto. 

887 

Gene Therapy Approaches Based on Bcl-2 to Increased 

Resistance of Human Cultured Keratinocytes for 

Transplantation 

Francisco Martínez-F, Araceli Barrera-L, Christian Y Lomeli-R, 

Erendira Estrada-V, Hugo Sandoval-Z, Hilda Villegas-C, 

Catalina Machuca-R, David T. Curiel, JA Madinaveitia-V, 

Alejandro Zentella- D. 

888 

Cell Carrier-Based Protection of Vesicular Stomatitis Virus 

(VSV) from Immune and Nonimmune Serum-Mediated 

Inactivation 

Mulu Z. Tesfay, Mark J. Federspiel, Glen N. Barber, Kah-Whye 

Peng, Stephen J. Russell. 


Abstract Directory Friday, May 20, 2011 



1:15 PM - 3:15 PM 

Room: 6A 

326 1:15 PM 

Adeno-Associated Virus Serotype 9 Uses Galactose as a 

Cellular Receptor To Transduce Conducting Airway 

Christie Bell, Luk Vandenberghe, Peter Bell, Maria P. Limberis, 

James M. Wilson. 

327 1:30 PM 

New Insight into Obstacles to Hematopoietic Stem and 

Progenitor Cell Transduction with rAAV2 Vectors 

Hao-Yuan Jiang, Yiwen Xiang, Bridget Lins, Angela E. Rivers, 

Mavis Agbandje-McKenna, Kirsten A. K. Weigel-Van Aken. 

328 1:45 PM 

Engineering Liver-Detargeted AAV9 Vectors for Cardiac 

and Musculo-Skeletal Gene Transfer 

Nagesh Pulicherla, Kelli D. Bryant, Sarah M. Brown, Mavis 

Agbandje-McKenna, Aravind Asokan. 

329 2:00 PM 

Functional Mapping of Tissue Tropism of Naturally 

Occurring Adeno-Associated Virus Isolates from Human 

Hematopoietic Stem Cells 

Laura J. Smith, Kim Van Vliet, Erin Miller, M. Ariel Kauss, Taihra 

B. Ul-Hasan, K. K. Wong, Mavis Agbandje-McKenna, Saswati 

Chatterjee. 

330 2:15 PM 

Site-Directed Mutagenesis of a Surface-Exposed Serine 

Residue Leads to High-Efficiency Transduction by 

Recombinant Adeno-Associated Virus 2 Vectors 

George V. Aslanidi, Lakshmanan Govindasamy, Chen Ling, 

Sergei Zolotukhin, Mavis Agbandje-McKenna, Arun Srivastava. 

331 2:30 PM 

Shuffled AAV Library Selection on Human Hepatocytes In 

Vivo 

Leszek Lisowski, Kirk Chu, Mark A. Kay. 

332 2:45 PM 

The Crystal Structure of AAV5: Role of Variable and 

Conserved Regions in Capsid Function 

Lakshmanan Govindasamy, Michael DiMattia, Brittney L. 

Gurda, Robert McKenna, John A. Chiorini, Nicholas Muzyczka, 

Sergei Zolotukhin, Mavis Agbandje-McKenna. 

333 3:00 PM 

Selection of Neutralizing Antibody-Resistant AAV8 Variants 

with Structure-Guided Site-Specific Saturated Mutagenesis 

Qiang Wang, Brittney Gurda, Luk Vandenberghe, Jing Lu, 

Sheng Li, James M. Wilson. 



Gene & Cell Therapy II 

1:15 PM - 3:15 PM 

Room: 606-607 

334 1:15 PM 

Prevention of Murine Autoimmune Diabetes by CCL22- 

Mediated T Regulatory Cell Recruitment to the Islet 

Joel Montane, Loraine Bischoff, Galina Soukhatcheva, Lei Dai, 

Paul Orban, Gijs Hardenberg, Megan Levings, Merce Obach, 

Rusung Tan, C. Bruce Verchere. 

335 1:30 PM 

Adeno-Associated Virus 8 (AAV8) Mediated Expression of 

XIAP in beta Cells Protects Islet Allografts in Diabetes 

Joel Montane, Merce Obach, Galina Soukhatcheva, C. Bruce 

Verchere. 

336 1:45 PM 

Lentiviral Vector Enhanced Haematopoietic Stem Cell 

Gene Therapy Corrects the Neurological Phenotype of 

Mucopolysaccharidosis IIIA Mice 

Alexander W. W. Langford-Smith, Fiona L. Wilkinson, Kia J. 

Langford-Smith, Ana Sergijenko, Rebecca Holley, William 

Bennett, Simon Howe, Adrian Thrasher, Catherine Merry, 

Simon Jones, J. Ed Wraith, Robert Wynn, Brian W. Bigger. 

337 2:00 PM 

Correction of Neurological Disease of 

Mucopolysaccharidosis IIIB in Adult Mice by rAAV9 Trans- 

Blood-Brain-Barrier Gene Delivery 

Haiyan Fu, Juliann DiRosario, Smruti Killedar, Kimberly 

Zaraspe, Douglas M. McCarty. 

338 2:15 PM 

Enhancement of Gene Therapy in Pompe Disease by 

Increased Mannose-6-Phosphate Receptor Expression in 

Target Tissues 

Dwight D. Koeberl, Baodong Sun, Jian Dai, Andrew Bird, 

Deeksha S. Bali. 

339 2:30 PM 

Preservation of Renal Function in Murine Glycogen Storage 

Disease Type I with a Double-Stranded Adeno-Associated 

Virus Vector 

Xiaoyan Luo, Songtao Li, Andrew Bird, Michelle P. Winn, 

Dwight D. Koeberl. 

340 2:45 PM 

Robust and Sustained Correction of OTC Deficiency 

in Adult Spfash Mice Using an AAV2/8-Based Vector 

Expressing Codon-Optimized Human OTC Gene 

Lili Wang, Jianping Lin, Hiroki Morizono, Peter Bell, David 

Jones, Deirdre McMenamin, Mark Batshaw, James M. Wilson. 


Friday, May 20


112 





1:15 PM - 3:15 PM 

Room: 606-607 

341 3:00 PM 

Long-Term Correction of Very Long-Chain Acyl-CoA 

Deydrogenase Deficiency by Recombinant Adeno- 

Associated Virus 9 Gene Therapy 

Allison M. Keeler, Glenn Walters, Thomas Conlon, Karin Green, 

Christian Mueller, Terence R. Flotte. 




1:15 PM - 3:15 PM 

Room: 611-612 

342 1:15 PM 

Maintenance of Hematopoietic Polyclonality 

after MGMTP140K-Mediated In Vivo Selection and 

Chemoprotection Following Multiple Cycles of 

Chemotherapy in Glioblastoma Patients 

Jennifer E. Adair, Brian C. Beard, Grant D. Trobridge, Maciej 

Mrugala, Hans-Peter Kiem. 

343 1:30 PM 

Molecular Follow-Up of the German WAS Clinical Gene 

Therapy Trial 

Anna Paruzynski, Kaan Boztug, Claudia Ball, Ali Nowrouzi, 

Christina Lulay, Marie Böhm, Sonja Naundorf, Klaus Kühlcke, 

Rainer Blasczyk, Irina Kondratenko, Laszló Maródi, Hanno 

Glimm, Christoph Klein, Christof von Kalle, Manfred Schmidt. 

344 1:45 PM 

Correction of Canine Pyuvate Kinase Deficiency by Foamy 

Virus Vector-Mediated MGMT-P140K Selection In Vivo 

Brian C. Beard, Robert A. Wu, Christina Ironside, Punam Malik, 

Hans-Peter Kiem, Grant D. Trobridge. 

345 2:00 PM 

Zinc Finger Nuclease Mediated Safe Harbor Targeted Gene 

Transfer in Patient iPSCs Functionally Corrects X-Linked 

Chronic Granulomatous Disease 

Colin L. Sweeney, Jizhong Zou, Bin-Kuan Chou, Uimook Choi, 

Jason Pan, Hongmei Wang, Sarah N. Dowey, Linzhao Cheng, 

Harry L. Malech. 

346 2:15 PM 

Long-Term Correction of Canine Leukocyte Adhesion 

Deficiency with a SIN Lentiviral Vector Using the Human 

PGK Promoter Expressing Canine CD18 

Michael J. Hunter, Huifen Zhao, Laura M. Tuschong, Tanya H. 

Burkholder, Derek A. Persons, Dennis D. Hickstein. 

347 2:30 PM 

Gamma-Retroviral Salvage Gene Therapy for Two Children 

with Chronic Granulomatous Disease 

Ulrich Siler, Janine Reichenbach, Anna Pruzynski, Manfred 

Schmid, Christoph von Kalle, Manuel Grez, Reinhard Seger. 

348 2:45 PM 

Alpharetroviral SIN Vectors: Evaluation of Genotoxicity and 

Long-Term Expression in Hematopoiesis 

Julia D. Suerth, Ute Modlich, Martijn H. Brugman, Tobias 

Maetzig, Verena Thies, Kerstin Kaufmann, Manuel Grez, 

Christopher Baum, Axel Schambach. 

349 3:00 PM 

Lentiviral Vectors Using a Ubiquitously Acting Chromatin 

Opening Element and Endogenous Btk Promoter 

Restore B and Myeloid Cell Defects in Murine X-Linked 

Agammaglobulinemia 

Hannah Kerns, Blythe Sather, Sara Mamman, Albanus 

Moguche, Michelle Brault, Alexander Astrakhan, Byoung Ryu, 

David Rawlings. 



Cancer Immunotherapy - 

Emphasis on Adoptive T Cell Transfer 

1:15 PM - 3:15 PM 

Room: 608-609 

350 1:15 PM 

Adoptive Transfer of “Stem Cell-Like” Anti-Tumor T Cells 

Can Eradicate Tumors 

Nicholas P. Restifo, Christopher D. Morrison, Pawel Muranski, 

Luca Gattinoni. 

351 1:30 PM 

Adoptive Transfer of Autologous IL13-zetakine + Engineered 

T Cell Clones for the Treatment of Recurrent Glioblastoma: 

Lessons from the Clinic 

Christine E. Brown, Renate Starr, Araceli Naranjo, Christine 

Wright, James Bading, Julie A. Ressler, Massimo D’Apuzzo, 

Behnam Badie, Stephen J. Forman, Michael C. Jensen. 

352 1:45 PM 

In Vivo Selection of Gene Modified T Cells by Engineering 

Resistance to Clinical Immunosuppressive Drugs 

Mycophenolate Mofetil and Methotrexate 

Mahesh Jonnalagadda, Christine E. Brown, Julie R. Ostberg, 

Wen C. Chang, Stephen J. Forman, Michael C. Jensen. 

353 2:00 PM 

Generating a Chimeric Antigen Receptor To Redirect T-Cell 

Specificity after Infusion 

Sonny O. Ang, Cassie Hartline, Tiejuan Mi, Sourindra N. Maiti, 

George W. Jackson, Helen Hul, Elizabeth Shpall, Dean A. Lee, 

Richard E. Champlin, Laurence J. N. Cooper.



Cancer Immunotherapy - 

Emphasis on Adoptive T Cell Transfer 

1:15 PM - 3:15 PM 

Room: 608-609 

354 2:15 PM 

Improved Costimulation of CD19-Specific T Cells 

Transpresenting a Membrane-Bound IL-15 

Lenka V. Hurton, Harjeet Singh, Simon Olivares, Laurence J. N. 

Cooper. 

355 2:30 PM 

Gene Transfer to Hematopoietic Stem/Progenitor Cells as 

a Novel Approach for Immunotherapy Against B-Lineage 

Malignancies 

Satiro N. Oliveira, Christine Ryan, Francesca Giannoni, 

Cinnamon Hardee, Behrod Katebian, Arineh Sahaghian, 

Roger Hollis, Donald B. Kohn. 

356 2:45 PM 

CD8:Class I MHC Interactions Influence T Cell Activity 

Mediated by Chimeric Antigen Receptors 

David H. Aggen, Jennifer D. Stone, Adam S. Chervin, Andrea 

Schietinger, Karin Schreiber, Hans Schreiber, David M. Kranz. 

357 3:00 PM 

Genetically Engineered T-Cells Targeting Cancer Associated 

Fibroblasts for Cancer Immunotherapy 

Sunitha Kakarla, Lisa Wang, David Rowley, Klaus Pfizenmaier, 

Stephen Gottschalk. 


Cancer-Oncolytic Viruses 

1:15 PM - 3:15 PM 

Room: 618-620 

358 1:15 PM 

Systemic Combination Virotherapy for Malignant 

Melanoma with Vesicular Stomatitis Virus and Adoptive T 

Cell Transfer 

Diana M. Rommelfanger, Phonphimon Wongthida, Karen 

K. Kaluza, Rosa M. Diaz, Jill M. Thompson, Timothy J. Kottke, 

Richard G. Vile. 

359 1:30 PM 

Enhancing Therapeutic Index of Oncolytic Vaccinia Virus 

through Combining MicroRNA Regulation and Thymidine 

Kinase Deletion 

Mina Hikichi, Minoru Kidokoro, Hisatoshi Shida, Hideaki 

Tahara, Takafumi Nakamura. 

360 1:45 PM 

Engineering Viruses To Enhance and Monitor Systemic 

Oncolytic Efficacy 

Shruthi Naik, Rebecca Nace, Glen Barber, Stephen J. Russell. 

361 2:00 PM 

Systemic Delivery of Reovirus in Combination with 

Carefully Scheduled Chemotherapy Cures Established 

Tumors 

Timothy Kottke, Jill Thompson, Rosa Diaz, Phonphimon 

Wongthida, Diana Rommelfanger, Gerry Nuovo, Matt Coffey, 

Peter Selby, Hardev Pandha, John Chester, Kevin Harrington, 

Alan Melcher, Richard Vile. 

362 2:15 PM 

Vstat120 Modulates the Innate Pro-Inflammatory Response 

to Oncolytic Virus 

Jayson Hardcastle, Jeffrey Wojton, Eric Wohleb, W. Hans 

Meisen, Christopher Alvarez-Breckenridge, M. Oskar Nowicki, 

Jonathan Godbout, Balveen Kaur. 

363 2:30 PM 

Vaccine, but Not Wild-Type, Measles Virus Infection Has 

Pleotropic Effects on Human Neutrophil Function – A 

Mechanistic Insight into the Effects of an Oncolytic Virus on 

the Innate Immune System 

Yu Zhang, Lena Rai, Bella Patel, Aditi Dey, Anna Castleton, 

Adele K. Fielding. 

364 2:45 PM 

Cyclophosphamide Controls the Humoral Response to 

Oncolytic Viruses 

Kah-Whye Peng, Andrew Greenslade, Rae Myers, Emily K. 

Mader, Suzanne M. Greiner, Mark J. Federspiel, Stephen J. 

Russell. 

365 3:00 PM 

Inhibition of Rho Associated Coiled-Coil Forming Kinase 

Increases Efficacy of Measles Virus Infection 

Mateusz Opyrchal, Ianko Iankov, Cory Allen, Evanthia Galanis. 



1:15 PM - 3:15 PM 

Room: 615-617 

366 1:15 PM 

Reprogramming Mouse iPS Cells as a New Approach To 

Correct the Stem Cell Defect in the Mpl -/- Mouse Model 

Jackie Roy, Angela Epp, Junli Feng, Xiaoping Wu, Neil C. 

Josephson. 

367 1:30 PM 

Targeting NF-kB Enhances the Regenerative Potential of 

Muscle Stem Cells through Multiple Mechanisms 

Jonathan D. Proto, Aiping Lu, Kayla Imbrogno, Ying Tang, Paul 

D. Robbins, Bing Wang, Johnny Huard. 


Friday, May 20


114 




1:15 PM - 3:15 PM 

Room: 615-617 

368 1:45 PM 

Recombinase Strategies To Make and Modify iPS Cells 

Marisa Karow, Christopher L. Chavez, Alfonso P. Farruggio, 

Jonathan M. Gesinger, Joseph C. Wu, Yanru Chen-Tsai, 

Michele P. Calos. 

369 2:00 PM 

Doxycyclin-Inducible Expression of Human Cytidine 

Deaminase (hCDD) in Hematopoietic Cells Mediates 

Protection Against Cytosine-Arabinoside Ara-C In Vitro and 

In Vivo 

Nico Lachmann, Nils Pfaff, Sebastian Brennig, Tobias Cantz, 

Axel Schambach, Christopher Baum, Thomas Moritz. 

370 2:15 PM 

Enhanced Cell Survival, Differentiation and Down- 

Regulation of Hypoxia-Related Genes by Increased Oxygen 

Supply 

Dmitriy Sheyn, Shimon Benjamin, Shiran Ben David, Ilan 

Kallai, Yoram Zilberman, Anthony Oh, Gadi Pelled, Dan Gazit, 

Zulma Gazit. 

371 2:30 PM 

In Vitro Reprogramming of Murine Gall Bladder Cells to 

beta-Like Cells 

Raymond D. Hickey, Kathryn M. Schubert, Jessie S. Coleman, 

Feorillo Galivo, Eric Lagasse, Markus Grompe. 

372 2:45 PM 

Improved Hematopoietic Stem/Progenitor Cell 

Maintenance of Nonhuman Primate Marrow Cells Via a 

Non-Cell-Autonomous Effect of Fos and Vps72 

Korashon L. Watts, Eric Deneault, Guy Sauvageau, Hans-Peter 

Kiem. 

373 3:00 PM 

Muscle Derived Stem Cells Transduced with BMP4 Interact 

Broadly with Host Cells To Promote Bone Healing in Critical 

Sized Skull Defect 

Xueqin Gao, Arvydas Usas, Aiping Lu, Jonathan Proto, Jessica 

C. Tebbets, Hongshuai Li, James H. Cummins, Mathieu Huard, 

Johnny Huard. 



Immunologic & Host Responses in 


1:15 PM - 2:15 PM 

Room: 602-604 

374 1:15 PM 

Characterizing AAV1 Capsid Antigenic Regions 

Yu-Shan Tseng, Brittney Gurda, Wendy Weichert, Colin R. 

Parrish, John A. Chiorini, Mavis Agbandje-McKenna. 

375 1:30 PM 

Avoiding Trangene Immune Rejection after AAV Vector 

Delivery to the Skeletal Muscle: Tolerogenic Dendritic Cell- 

Based Immunotherapy in a Nonhuman Primate Model 

Aurélie Moreau, Mercedes Segovia, Laurence Dubreil, Gaëlle 

Tilly, Jack-Yves Deschamps, Yan Cherel, Ignacio Anegon, 

Philippe Moullier, Maria Cristina Cuturi, Oumeya Adjali. 

376 1:45 PM 

Immunosuppressive Strategies To Protect Transgenic Skin 

Cells from Immune Rejection: Implications for Cutaneous 

Gene/Cell Therapy 

Soosan Ghazizadeh, Weibing Zhang, Li T. Huang. 

377 2:00 PM 

Hepatocyte-Targeted Expression by Integrase-Defective 

Lentiviral Vectors Induces Antigen-Specific Regulatory T 

Cells and Immune Tolerance to Foreign Antigens 

Andrea Annoni, Alessio Cantore, Kevin Goudy, Lucia Sergi 

Sergi, Luigi Naldini, Maria Grazia Roncarolo. 



2:30 PM - 3:30 PM 

Room: 602-604 

378 2:30 PM 

Micro RNA Knockdown Significantly Enhances Adenovirus 

Replication and Vector Production 

Christina Rauschhuber, Martin Hausl, Dirk Nettelbeck, Anja 

Ehrhardt. 

379 2:45 PM 

GMP Production of a SIN Lentiviral Vector for the Treatment 

of SCID-X1 Using a Stable Producer Cell Line 

Tim Lockey, Susan Sleep, Robert Throm, Mike Greene, Paolo 

Fagone, Harry Malech, Brian Sorrentino, John T. Gray.




2:30 PM - 3:30 PM 

Room: 602-604 

380 3:00 PM 

Generation and Characterization of AAV Producer Cell 

Lines 

John Martin, Amy Frederick, Yuxia Luo, Robert Jackson, 

Dianna Ambach, Christopher Renzi, Lisa Budzinski, Lois 

Horton, Angela Johnsen, Simon Godwin, Donna Armentano, 

Sam Wadsworth, Karen Vincent. 

381 3:15 PM 

A New Cell Line for Clinical Grade Production of E1-Deleted 

Adenovirus Encoding Toxic Proteins 

Rénald Gilbert, Claire Guilbault, David Gagnon, Danielle 

Jacob, Lucie Bourget, Amine Kamen, Bernard Massie. 

POSTER SESSION II 

4:40 PM - 6:40 PM 

Room: Hall 4B 

RNA Virus Vectors II 

382 

Rapid Titration of Lentiviral and Gamma Retroviral 

Vectors Using a Beta-Lactamase Protein Fragment 

Complementation Assay 

Wu Ou, Connie Lu, Jakob Reiser. 

383 

Insulated Lentiviral Vectors towards Safer Gene Transfer to 

Stem Cells 

Caroline Duros, Alexandre Artus, Armelle Gaussin, Scholtz 

Simone, Daniela Cesana, Eugenio Montini, Manfred Schmidt, 

Christof von Kalle, Nicolas Mermod, Odile Y. D. Cohen- 

Haguenauer, Odile Y. D. Cohen-Haguenauer. 

384 

Generation of Transgene-Free Induced Pluripotent Stem 

Cells Using Polycistronic Foamy Virus Vectors 

Iram F. Khan, Jordan Kho, David R. Deyle, Yi Li, David W. 

Russell. 

385 

Increasing Lentiviral Transduction by MG132- and CSP- 

Induced Inhibition of the Innate Immune Response 

Naoya Uchida, Matthew M. Hsieh, Kareem N. Washington, 

John F. Tisdale. 

386 

Selective Gene Transfer Do CD105 Positive Cells – Targeting 

Mesenchymal Stroma Cells 

Tobias Abel, Irene Schneider, Klaus Cichutek, Christian J. 

Buchholz. 

387 

Engineered Lentiviral Vectors Pseudotyped with a CD4 

Receptor and a Fusogenic Protein Can Target Cells 

Expressing HIV-1 Envelope Proteins 

Chi-Lin Lee, Jason Dang, Kye-Il Joo, Pin Wang. 


389 

Directed Integration of Insulated Lentiviral Vectors to the 

Heterochromatin towards Safer Gene Transfer to Stem Cells 

Alexandre Artus, Caroline Duros, Yaïr Botbol, Simone Scholtz, 

Manfred Schmidt, Christof von Kalle, Marc Lavigne, Odile Y. D. 

Cohen-Haguenauer, Odile Y. D. Cohen-Haguenauer. 

390 

Retroviral Delivery of Episomal Vectors 

Julie Lemay, Claudia Hagedorn, Elena Kuzmenko, Hans- 

Joachim Lipps, Reinhard Seger, Janine Reichenbach, Ulrich 

Siler. 

391 

Optimal Promoter Usage for Lentiviral Vector-Mediated 

Transduction of Different Cell Lines 

Ling Zhang, Pengyu Sun, Wenjing Wang, Junwen Shi, Dong 

Xiao, Jinlang Qiu, Jingbo Wu, Wanlong Tan, Hongwei Li, 

Chengyao Li. 


392 

Biodistribution of IV Injected AAV9 in Young Cynomolgus 

Macaques 

Kevin D. Foust, Adam K. Bevan, Lyndsey Braun, Leah 

Schmelzer, Pablo R. Morales, Brian K. Kaspar. 

393 

Terminal N-Linked Galactose Is the Primary Receptor for 

Adeno-Associated Virus Serotype 9 (AAV9) 

Shen Shen, Kelli D. Bryant, Sarah M. Brown, Aravind Asokan. 

394 

Rational AAV Capsid Engineering Via Peptide Insertion 

Reveals Critical Roles of the Underlying Vector Serotype 

Marina Bechtle, Eike Kienle, Teresa Pankert, Dirk Grimm. 

395 

Quantitatively Dissecting Viral Trafficking Kinetics at Single 

Particle Level 

Ping-Jie Xiao, Richard J. Samulski. 

396 

Structurally Annotating the Tropism and Transduction 

Determinants of AAV1 and AAV6 

Robert Ng, Mavis Agbandje-McKenna. 


Friday, May 20


116 


POSTER SESSION II — continued 

4:40 PM - 6:40 PM 

Room: Hall 4B 


397 

A Potential Breakthrough in the AAV Biology: A Novel High- 

Throughput Capsid Functional Analysis Using Barcoded 

AAV Libraries and a Deep Sequencing Technology 

Kei Adachi, Tatsuji Enoki, Christopher S. Naitza, Hiroyuki 

Nakai. 

398 

Adeno-Associated Virus 2 Infection Requires Endocytosis 

through the CLIC/GEEC Pathway 

Matthieu Nonnenmacher, Thomas Weber. 

399 

AAV2 and AAV8 as Gene Therapy Vectors Targeting Distal 

Lung Epithelial Progenitor Cells 

Benjamin R. Steines, David D. Dickey, Boulos S. Nassar, Joseph 

Zabner, Xiaopeng Li. 

400 

Characterization of Chimpanzee-Derived Novel Natural 

Variants of AAV5 

Li Zhong, Mengxin Li, Jun Xie, Qin Su, Ran He, Yu Zhang, 

Jason Goetzmann, Terry Flotte, Guangping Gao. 

401 

Widespread Transduction of Brain Parenchyma after 

Intraventricular Injection of AAV9 Compared to AAV4 and 

AAV5 

Annagiusi Gargiulo, Nicolina C. Sorrentino, Carmine 

Spampanato, Alessandro Fraldi, Enrico M. Surace. 

402 

High-Efficiency Transduction of Primary Human 

Monocytes-Derived Dendritic Cells (moDCs) by 

Recombinant Adeno-Associated Virus Vectors Containing a 

Point Mutation in the Surface-Exposed Serine Residue 

George V. Aslanidi, Chen Ling, Ashley T. Martino, Lakshmanan 

Govindasamy, Mavis Agbandje-McKenna, Roland W. Herzog, 

Arun Srivastava. 

403 

A Capsid Composition Variant Containing four VP Proteins 

Caused by a Novel Start Codon at Position 219 of the 

Nucleotide Sequence of AAV8 Cap 

Olga Zelenaia, Federico Mingozzi, Bernd Hauck, Shangzhen 

Zhou, Katherine A. High, J. Fraser Wright. 

404 

Systematical Evaluation of Tropism of Different AAV 

Serotype Vectors in Adult and Neonatal Mice Following I.V. 

Injections 

Li Zhong, Mengxin Li, Xin Mu, Christopher Boisvert, Dmitry 

Ratner, Qin Su, Ran He, Sheng Chen, Jun Xie, Yu Zhang, 

Hongwei Zhang, Daniel Lucking, Terry Flotte, Guangping Gao. 

405 

A Rationally Designed Synthetic Combinatorial AAV Capsid 

Library as a Gene Therapy Tool 

Damien Marsic, Sergei Zolotukhin, Lakshaman Govindasamy, 

Babak Moghimi, Daniela Hurtado. 

406 

Development of Optimized AAV3 Serotype Vectors: 

Mechanism of High-Efficiency Transduction of Human Liver 

Cancer Cells 

Binbin Cheng, Chen Ling, Yao Dai, Lyudmyla G. Glushakova, 

Yuan Lu, Samantha W. Y. Gee, Katherine E. McGoogan, George 

V. Aslanidi, Morag Park, Peter W. Stacpoole, Dietmar Siemann, 

Arun Srivastava, Changquan Ling. 

407 

Development of a Simple and Serotype-Independent 

System To Assess the AAV Assembly-Activating Protein 

(AAP) Function 

Tatsuji Enoki, Kei Adachi, Christopher S. Naitza, Hiroyuki 

Nakai. 

408 

Directed Evolution of Adeno-Associated Virus: 

Construction of an Enriched Random Insertion Library 

and Artificial Selection To Identify Structure-Function 

Relationships 

Justin H. Judd, Jonathan Silberg, Junghae Suh. 



409 

Necrosis and Autophagy, but Not Apoptosis, Are Induced 

in Macrophages In Vivo upon Interaction with Adenovirus 

Nelson C. Di Paolo, Dmitry M. Shayakhmetov. 

410 

Adenovirus-Mediated NIS Expression in Xenografted 

Prostate Tumors Requires a Minimal Threshold of Viral Dose 

for Efficient Radioiodine Uptake 

Miguel A. Trujillo, Michael J. Oneal, Samantha McDonough, 

John C. Morris. 

411 

Cancer Specific Peptide-Tagged Ad Vectors in Systemic 

Therapy of Aggressive Solid Tumors 

Anke Schmidt, Christian Eipel, Katharina Fürst, Nadine 

Sommer, Jens Pahnke, Brigitte M. Pützer.



4:40 PM - 6:40 PM 

Room: Hall 4B 


412 

Enhancing Therapeutic Effects of Oncolytic Agents through 

Switching of Mechanism of Tumor Killing 

Hannah Chen, Padma Sampath, Wei Hou, Rachel Sikorski, 

Stephen H. Thorne. 

413 

A Novel Adenoviral Hybrid-Vector System Carrying a 

Plasmid Replicon for Safe and Efficient Cell and Gene 

Therapeutic Applications 

Richard Voigtlander, Martin Hausl, Rudolf Haase, Armin 

Baiker, Anja Ehrhardt. 

414 

Chimeric Serotype 5/6 Helper-Dependent Ad Vector 

Improves Therapeutic Index for Liver-Directed Gene 


Francesco Vetrini, Reeti Khare, Nathan C. Grove, Donna J. 

Palmer, Amanda Rosewell, Michael A. Barry, Philip Ng. 

415 

A Novel Protein Transduction Domain with Improved 

Secretion and Transduction Activity 

Ying Shen, William Yu, Poonam Nagpal, John G. Hay, Harald 

Sauthoff. 

416 

Traceless Bioresponsive Coating of Adenovirus Vectors 

Jan-Michael Prill, Vladimir Subr, Tatjana Engler, Karel Ulbrich, 

Stefan Kochanek, Florian Kreppel. 

417 

Scalable Production and Purification Process of Helper- 

Dependent Adenoviral Vectors Using a Recombinase-Free 

System 

Dan Cots, Meritxell Puig, Maria Mercedes Segura, Assumpció 

Bosch, Miguel Chillón. 

418 

Carrier Cells Infected with IAI.3B Promoter-Driven 

Oncolytic Adenovirus Overcome Immunogenicity and 

Induce Complete Tumor Reduction in Oral Squamous 

Carcinoma Cells 

Katsuyuki Hamada, Ting Zhang, Koh-ichi Nakashiro, Hiroyuki 

Hamakawa. 

419 

Characterization of Poly(I) as a Tool To Improve Liver 

Transduction by HDAd Vectors 

Francesco Vetrini, Nathan Grove, Donna Palmer, Philip Ng, 

Nicola Brunetti-Pierri. 

420 

Transient Immunossuppression with CsA in Adenovirus- 

Sensitized Cirrhotic Rats Increases Survival and Reduces 

Inflammation Maintaining Adenovector Biodistribution 

and Transgene Effectiveness 

Ana Sandoval-Rodriguez, Mayra Mena-Enriquez, 

Jesus Garcia-Bañuelos, Adriana Salazar-Montes, Juan 

Armendariz-Borunda. 

421 

Oncolytic Adenovirus Regulated by Modified AFP Promoter 

Induces Hepatocellular Carcinoma-Specific and Hypoxia- 

Independent Cell Killing 

Minjung Kim, Oh-Joon Kwon, Il-Kyu Choi, Ji Young Yoo, 

Soung-Kyung Lee, Chae-Ok Yun. 


422 

Targeted Gene Integration into a Mouse Safe Harbor Locus 

Directed by Engineered Zinc Finger Nucleases 

Pablo Perez-Pinera, David G. Ousterout, Matthew T. Brown, 

David Yudovich, Charles A. Gersbach. 

423 

Correction of Adenosine Deaminase Deficiency Using Zinc 

Finger Nucleases 

Alok V. Joglekar, Gabriela Kuftinec, Jason Sims, Andreas Reik, 

Colin Flinders, Michael C. Holmes, Philip D. Gregory, Roger P. 

Hollis, Donald B. Kohn. 

424 

An Insight into the Chromatin-Based Mechanism of In Vivo 

Silencing of Foreign DNA 

Lia E. Gracey, Zhi-Ying Chen, Neil Phillips, Jay M. Maniar, 

Andrew Z. Fire, Mark A. Kay. 

425 

Meganucleases for Gene Therapy 

Julianne Smith, Cécile Schiffer-Mannioui, Laurent Poirot, 

Roman Galetto, Agnès Gouble, Carole Desseaux, Frédéric 

Paques. 

426 

Characterization of Dynamic Change in the Distribution of 

the Integration Sites of the Sleeping Beauty Transposon 

Nataly A. Kacherovsky, C. Anthony Blau, Cecilia M. Giachelli, 

Suzie H. Pun. 

427 

Passive Topical Administration of Nucleic Acids to Targeted 

Skin Cells Via Sub-50 Nanometer Capsules 

Gretchen M. Unger, Martha Fuentes de Albin, Roger L. Kaspar, 

Betsy T. Kren, Diane K. Tobolt, Michael P. Murtaugh. 


Friday, May 20


118 



4:40 PM - 6:40 PM 

Room: Hall 4B 


428 

Sensitive Methods To Detect Mutations Induced by 

Meganucleases 

Jacques P. Tremblay, Joël Rouseau, Pierre Chapdelaine, 

Sébastien Boivert, Luciana Almeida, Jacques Corbeil, 

Alexandre Montpetit, Frédéric Pâques. 

429 

Combining Linear Expression Cassette Technology with 

Novel Electroporation Techniques To Deliver Influenza DNA 

Vaccines 

Xuefei Shen, Feng Lin, Gary Kobinger, Elizabeth E. Murray, 

Kate E. Broderick, Niranjan Y. Sardesai. 

430 

Mechanisms of Enhanced Gene Expression by Gene 

Transfer Using Ultrasound-Responsive and Mannose- 

Modified Gene Carriers 

Keita Un, Shigeru Kawakami, Mitsuru Yoshida, Ryo Suzuki, 

Kazuo Maruyama, Fumiyoshi Yamashita, Mitsuru Hashida. 


432 

Construction and Characterization of Ligand-Streptavidin 

Fusion Proteins for Targeting of Biotinylated DNA 

Nanoparticles 

Wenchao Sun, Pamela B. Davis. 

433 

Octaarginine- and pH Sensitive Fusogenic Peptide- 

Modified Nanoparticles for Liver Gene Delivery 

Yasuhiro Hayashi, Ryoichi Mizuno, Khalil A. Ikramy, Hideyoshi 

Harashima. 

434 

Oligonucleotides Delivery Using High-Pressurized 

Lipoplexes 

Tsuyoshi Kimura, Asami Sano, Kwangwoo Nam, Yoshihiro 

Sasaki, Kazunari Akiyoshi, Akio Kishida. 

435 

Aptamer Conjugated Liposomes (Aptamosomes) as an 

Efficient Detection/Delivery Nano-Vehicle toward Prostate 


Keun-Sik Kim, Seho Kim, Hyun-Mi Kwon, Gwang-Hyun Lee, 

Yong Serk Park, Dong-Eun Kim. 

436 

Dual pH Response Nanoparticles for Gene Delivery 

Jose M. Morachis, Enas A. Mahmoud, Jagadis 

Sankaranarayanan, Jenny Huang, Adah Almutairi. 

437 

The Interaction between SP100 and Rep78 Inhibits Rep- 

Dependent Integration and Mediates SP100 Degradation 

Jinzhong Chen, Yuan-Yuan Xue, Ran Wang, Yang-bo Yue, Jinglun 

Xue. 

438 

Rep of AAV Protects p53 from E1B Mediated p53 Nucleolus 

Egress and Degradation 

Xu Wang, Jing-lun Xue, Wenjuan Li, Jinzhong Chen, Jinjin Wang. 


The Role and Fate of Excess Polycations in Chitosan-Based 


Marc Thibault, Melina Astolfi, Marc Lavertu, Vincent Darras, 

Michael D. Buschmann. 



439 (MOVED TO ORAL ABSTRACT SESSION 413) 

Genetic Electrotransfer Immunization for the Identification 

of Functionally Important Epitopes: The Example of 

VAR2CSA in Placental Adhesion of Plasmodium Falciparum 

Infected Erythrocytes 

S. Gnidehou, P. Bigey, J. Doritchamou, M. Quiviger, F. Viwami, 

A. Couturier, A. Salanti, Daniel Scherman, P. Deloron, N. Tuikue 

Ndam. 

440 

Enhanced Gene Gun-Based Gene Delivery to the Liver 

through Trans-Peritoneal Bombardment 

Kohei Tatsumi, Kazuo Ohashi, Tomohiko Yamazaki, Akiyoshi 

Taniguchi, Teruo Okano. 

441 

Electroporation Parameters Utilized for Delivering 

Plasmids Encoding Cytokines Impact the Outcome of 

Melanoma Therapy 

Shawna A. Shirley, Richard Heller. 

442 

Generating Defined, Characterized Microbubbles To 

Enhance the Efficiency of Ultrasound-Mediated Gene 

Delivery System In Vitro 

Samuel S. Sun, Misty L. Noble, Milo C. Snyder, Adrienne 

Rothschilds, Carol H. Miao. 

443 

phiC31 Integrase-Mediated Long-Term Gene Expression in 

the Cultured Renal Cell Lines and Murine Kidney 

Shigeru Kawakami, Yuki Otani, Hidefumi Mukai, Yoshiaki 

Umemoto, Fumiyoshi Yamashita, Mitsuru Hashida. 

444 

Hydrodynamic Limb Vein Injection Method Can Open an 

Avenue of Mitochondrial Gene Delivery In Vivo 

Yukari Yasuzaki, Yuma Yamada, Tsutomu Kanefuji, Dexi Liu, 

Hideyoshi Harashima.



4:40 PM - 6:40 PM 

Room: Hall 4B 


445 

Utilization of a Single Method for Transfection of Multi- 

Cistronic Plasmids, mRNA and Protein in Primary Human 

Dermal Fibroblasts 

Laura A. Vozza-Brown, Uma Lakshmipathy, Reut Mali, Kristin 

Wiederholt. 

446 

Therapeutic Ultrasound Promotes Plasmid DNA Uptake by 

Clathrin-Mediated Endocytosis 

Daisy Bentes de Paula, Valderez Bastos Valero-Lapchik, Edgar 

Julian Paredes-Gamero, Sang Won Han. 

447 

Importance of Electrode Choice on Gene Electrotransfer 

to Skin; Evaluated by Efficacy of Transgene Expression and 

Electric Field Calculation in a Porcine Model 

Anita Gothelf, Faisal Mahmood, Frederik Dagnaes-Hansen, 

Julie Gehl. 


449 

Nanoparticle-Mediated Gene Transfer in an In Vitro Model 

of Human Trophoblasts 

Helen Jones, Donglu Shi, Foong-Yen Lim, Sundeep Keswani, 

Timothy Crombleholme, Mounira Habli. 

450 

Aerosol Delivery of Plasmid DNA in a Mesh Nebuliser: 

Formulation and Transfection Studies 

Eugene R. Arulmuthu, Andrew S. Tait, David J. Williams, Henk 

K. Versteeg, John Ward, Mike Hoare. 



451 

Fetal Gene Therapy for Lethal Murine Hypophosphatasia 

Hanako Sugano, Tae Matsumoto, Koichi Miyake, Atsushi 

Watanabe, Sonoko Narisawa, José L. Millán, Yoshitaka 

Fukunaga, Takashi Shimada. 

452 

A Mouse Model To Test Liver-Targeted Therapies for MUT 

Methylmalonic Acidemia 

Julien S. Sénac, Justin R. Sysol, Irini Manoli, Randy J. Chandler, 

Charles P. Venditti. 

453 

rAAV8 Gene Delivery Demonstrates Potential Efficacy as a 

Treatment of Cardiomyopathy in Propionic Acidemia 

Randy J. Chandler, Nuria Carrillo-Carrasco, Suma 

Chandrasekaran, Patricia M. Zerfas, Charles P. Venditti. 

454 

AAV Mediated Gene Transfer to Skeletal Muscle Results in 

Sustained Reduction of Hyperbilirubinemia in an Animal 

Model of Crigler-Najjar Syndrome Type 1 

Nunzia Pastore, Rosa Maria Sepe, Francesco Vetrini, Edoardo 

Nusco, Alberto Auricchio, Nicola Brunetti-Pierri. 

455 

Neonatal Delivery of scAAV9-SMN: Impact of Disease 

Development in Two Models of Spinal Muscular Atrophy 

Jacqueline Glascock, Monir Shababi, Christian Lorson. 

456 

Successful Treatment of Hypophosphatasia Model Mice 

by a Single Intramuscular Injection of AAV Type 8 Vector 

Expressing Tissue-Nonspecific Alkaline Phosphatase 

Tae Matsumoto, Koichi Miyake, Noriko Miyake, Hideo Orimo, 

Sonoko Narisawa, José Millán, Yoshitaka Fukunaga, Takashi 

Shimada. 

457 

Successful Use of Lipoplex for Delivery of the 

Small Molecules ManNAc and Sialic Acid To Rescue 

Hyposialylation in a Mouse Model of Hereditary Inclusion 

Body Myopathy (HIBM) 

Tal Yardeni, Carla Ciccone, Shelley Hoogstraten-Miller, Daniel 

Darvish, Yair Anikster, John Nemunaitis, Phil Maples, Chris M. 

Jay, William A. Gahl, Marjan Huizing. 

458 

Gene Therapy with Small Heat Shock Protein for 

Huntington Disease 

Wuh-Liang Hwu, Yu-May Lee, Nathalie Clement, Ni-Chung 

Lee, Barry Byrne. 

459 

Gene Transfer of Constitutively Active Akt1 Increases Islet 

Cell Survival and Proliferation 

Robert N. Bone, Yuan Zhang, Mert Icyuz, Stacie M. J. Bryant, 

Henry K. Fortinberry, John A. Thompson, Gene P. Siegal, 

Hongju Wu. 

460 

Helper-Dependent Adenoviral Vectors for Liver-Directed 

Gene Therapy of Primary Hyperoxaluria Type 1 

Raffaele Castello, Pasquale Piccolo, Roberta Borzone, Riccardo 

Sangermano, Donna Palmer, Philip Ng, Nicola Brunetti-Pierri. 


Friday, May 20


120 



4:40 PM - 6:40 PM 

Room: Hall 4B 



461 

Administration of Gene Therapy Improves Cholesterol 

Synthesis and Physical Outcome in a Mouse Model of 

Smith-Lemli-Opitz Syndrome (SLOS) 

Lee Ying, Xavier Matabosch, Montserrat Serra, Cedric 

Shackleton, Gordon Watson. 

462 

Proliferative Adipocytes as Therapeutic Gene Vehicle 

toward Sustained Protein Replacement Therapy 

Masayuki Kuroda, Sakiyo Asada, Yasuyuki Aoyagi, Shigeaki 

Tanaka, Shunichi Konno, Masami Tanio, Masayuki Aso, Yasushi 

Saito, Hideaki Bujo. 

463 

Knockdown of Genes Upstream of the Tyrosine Catabolic 

Pathway with siRNA Can Partially Rescue the Phenotype of 

Fah Mutant Mice 

Changsheng Guo, Zhongya Wang, Sally Fitch, Markus 

Grompe. 

464 (MOVED TO POSTER SESSION I AFTER ABSTRACT 193) 

Hematopoietic Differentiation of Airway Epithelial Cell-Derived 

Cystic Fibrosis (CF) Induced Pluripotent Stem (iPS) Cells 

R. Geoffrey Sargent, Yanu Yang, Albert Lee, Marcus O. 

Muench, Soya Kim, Arash Bedayat, Layli Jamali, Lin Ye, Judy 

Chang, Dieter C. Gruenert. 


465.5 

Direct Gene Transfer with Compacted DNA Nanoparticles 

in Retinal Pigment Epithelial Cells: Expression, Repeat 

Delivery and Lack of Toxicity 

Zongchao Han, Adarsha Koirala, Rasha Makkia, Mark J. 

Cooper, Muna I. Naash 


466 

Evaluation of rAAV6-Microutrophin Expression Driven 

by a Highly Active Muscle Specific Regulatory Cassette in 

Dystrophic Mice and the Non-Human Primate 

Guy L. Odom, Glen B. Banks, Quynh Nguyen, Eric Finn, James 

M. Allen, Jacqueline Wicki, Stephen D. Hauschka, Jeffrey S. 

Chamberlain. 

467 

RNAi Therapy for Dominant Limb Girdle Muscular 

Dystrophy Type 1A 

Jian Liu, Lindsay M. Wallace, Sara E. Garwick-Coppens, 

Michael A. Hauser, Jerry R. Mendell, Scott Q. Harper. 

468 

Fukutin-Related Protein Knock-Down by Systemic AAV9shRNA 

Delivery or by Transgenic Knock-In Mutation 

Resulted in Similar Muscle and Heart Pathology of LGMD 2I 

Chi-Hsien Wang, Yiumo M. Chan, Bin Xiao, Chunping Qiao, 

Ru-Hang Tang, Hui Zheng, Elizabeth Keramaris-Vrantsis, Juan 

Li, Peijuan Lu, Qilong Lu, Xiao Xiao. 

469 

Regeneration of Large Segmental Bone Defects by 

Implantation of Gene Activated Fat Tissue 

Volker M. Betz, Oliver B. Betz, Peter Augat, Stefan Rammelt, 

Hans Zwipp. 

470 

Site Directed Gene Repair of the Dystrophin Gene 

in Satellite Cells Mediated by PNA-ssODNs Restores 

Dystrophin Expression into Skeletal Muscles of a Mouse 

Model for Duchenne Muscular Dystrophy 

Farnoosh Nik-Ahd, Refik Kayali, Carmen Bertoni. 

471 

Losartan Enhances the Success of Myoblast Transplantation 

Raouia Fakhfakh, Yann Lamarre, Daniel Skuk, Jacques P. 

Tremblay. 

472 

The Polyproline Site in Hinge 2 of Microutrophin Does 

Not Lead to Structural Abnormalities like That for 

Microdystrophin 

Glen B. Banks, Guy L. Odom, Eric E. Finn, Jeffrey S. 

Chamberlain. 

473 

Long-Term Engraftment of Mesenchymal Stromal Cells 

That Can Differentiate To Form Myogenic Cells in Dog with 

Duchenne Muscular Dystrophy 

Yuko Nitahara Kasahara, Hiromi Hayashita Kinoh, Hironori 

Okada, Jin-Hong Shin, Akiyo Nishiyama, Sachiko Ohshima 

Hosoyama, Michiko Wada Maeda, Akinori Nakamura, Takashi 

Okada, Shin’ichi Takeda. 

474 

Gene-Targeted Osteogenesis Imperfecta iPSCs Express 

Normal Collagen and Produce Bone after Mesenchymal 

Differentiation 

David R. Deyle, Iram F. Khan, Gaoying Ren, Peirong Wang, 

Ulrike Schwarze, Jordan Kho, Peter H. Byers, David W. Russell. 




4:40 PM - 6:40 PM 

Room: Hall 4B 


475 

Recombinant AAV6 Fails to Effectively Transduce Satellite 

Cells In Vivo 

Patryk Konieczny, Andrea Arnett, Julian N. Ramos, Zipora 

Yablonka-Reuveni, Jeffrey S. Chamberlain. 

476 

Molecular Treatment of Muscle Atrophy Caused by Focal 

Nerve Injury 

Gabriela A. Niizawa, Hiroyuki Nakai, Bing Wang, Paula R. 

Clemens. 

477 

AAV-5 Maximizes Growth Factor Transgene Expression and 

Differentiated Function in Chondrocyte Monolayer and 

Suspension Culture 

Alan J. Nixon, Laila Begum, Kyla O. Ortved. 

478 

Muscle Directed Gene Therapy with Capsid Modified 

Helper-Dependent Adenoviral Vectors 

Kilian Guse, Gautam Sule, Masataka Suzuki, Vincenzo Cerullo, 

Akseli Hemminki, Brendan Lee. 

479 

Exploring the Role of Deubiquitinating Enzyme A20 for 

Treatment of Muscular Dystrophy in mdx Mice 

Rakshita Charan, Gabriela Niizawa, Hiroyuki Nakai, Paula R. 

Clemens. 

480 

Interleukin-1β and Tumor Necrosis Factor-α Knockdown 

in Chondrocytes by Short Interfering RNA Using a Dual 

Expression Long Hairpin Construct 

Alan J. Nixon, Michael S. Scimeca. 

481 

Low-Level Expression of a Near-Full Length Dystrophin 

Improves Muscle Force and Lifespan in a Strain of Severely 

Affected Dystrophin/Utrophin Double Knockout Mice 

Dejia Li, Yongping Yue, Dongsheng Duan. 

482 

Osteoinduction in Muscle Tissue after Transduction with 

Bone Morphogenetic Protein-9: Implications for Bone 

Repair 

Volker M. Betz, Oliver B. Betz, Irina Weinzierl, Stefan Rammelt, 

Peter E. Mueller, Hans Zwipp. 

483 

PMO Delivery Systems with Bubble Liposomes and 

Ultrasound Exposure into Skeletal Muscles of the mdx Mice 

Yoichi Negishi, Yuko Ishii, Shoko Sekine, Yoko Endo-Takahashi, 

Ryo Suzuki, Kazuo Maruyama, Yukihiko Aramaki. 


484 

Zinc Finger Mediated Disruption of CXCR4 in CD4 T Cells 

Allows Protection and Enrichment in Humanized Mice after 

HIV-1 Challenge 

Jinyun Yuan, Jianbin Wang, Karen Crain, Philip D. Gregory, 

Michel C. Holmes, Bruce E. Torbett. 

485 

Protection of CD4 + T-Cells and Enhanced Immune Response 

Against SHIV-Challenge after Engraftment of Genetically- 

Modified HSCs in the Pigtailed Macaque-AIDS Model 

Patrick Younan, Patricia Polacino, On Ho, Brian Beard, Grant 

Trobridge, Shiu-Lok Hu, Hans-Peter Kiem. 

486 

LEDGF/p75 Based Gene Therapy for HIV/AIDS 

Sofie Vets, Janine Kimpel, Dorothee von Laer, Zeger Debyser, 

Rik Gijsbers. 

487 

Killing One Bird with Two Stones – Single shRNA Targeting 

Both Strands of HCV 

Leszek Lisowski, Menashe Elazar, Kirk Chu, Jeffrey S. Glenn, 

Mark A. Kay. 


489 

Expression of Anti-HIV-1 Short Hairpin RNAs Using PolIII- 

Based Transcriptions Systems 

Lisa J. Scherer, Karl A. Haushalter, Athena Anderson, John J. 

Rossi. 

490 

Epitopes Expressed in Different Loops of Adenovirus Fiber 

Induce Different Levels of Epitope-Specific Immunity 

Anurag Sharma, Anja Krause, Wen Zhu, Stefan Worgall. 

491 

The Analysis of Utility of Human Adenovirus Vectors 

for Killing Macrophages Infected with Mycobacterium 

tuberculosis 

Nelson C. Di Paolo, Shahin Shafiani, Kevin Urdahl, Dmitry M. 

Shayakhmetov. 

492 

An Enhanced DC-Targeting Lentivector Vaccine to HIV-1 

Gag by PD-1 Blockade 

Bingbing Dai, Lili Yang, Pin Wang. 


Friday, May 20


122 



4:40 PM - 6:40 PM 

Room: Hall 4B 


493 

Muliplexing Small Nucleolar RNAs To Inhibit HIV-1 

Replication 

Janet Chung, Jane Zhang, John Rossi. 

494 

Engineering Immunity Against HIV — Lentiviral-Vector 

Mediated Delivery of Broadly Neutralizing Antibodies as 

Pre-Exposure Prophylaxis for HIV 

Kenneth K. Yu, Kiefer Aguilar, David Baltimore. 

Cancer - Immunotherapy II 

495 

Effective Eradication of Established Ovarian Murine Tumors 

with MUC16 Targeted T Cells Expressing IL-12 Gene 

Alena A. Chekmasova, Samith Sandadi, Yan Nikhamin, David 

R. Spriggs, Renier J. Brentjens. 

496 

T Cells Redirected Against HER2 for the Adoptive 

Immunotherapy of HER2-Positive Malignancies 

Nabil Ahmed, Vita Salsman, Oumar Diouf, Aidin Ashoori, 

Claudia Gerken, Lisa Wang, Peter Anderson, Benjamin Musher, 

Shanda Blackmon, Teresa Hayes, John Hicks, Hao Liu, Winfried 

Wels, Catherine Bollard, Cliona Rooney, Gianpietro Dotti, Adrian 

Gee, Malcolm Brenner, Helen Heslop, Stephen Gottschalk. 

497 

A Recombinant Dimeric Ad3 Fiber Protein Triggers 

Opening of Epithelial Junctions in Solid Tumors and 

Improves Trastuzumab/Herceptin and Cetuximab/Erbitux 

Therapy in Mouse Models 

Ines Beyer, Hongjie Wang, ZongYi Li, Roma Yumul, Andre Lieber. 

498 

Genetic Editing of T Lymphocyte Specificity for Safe and 

Effective Adoptive Immunotherapy 

Pietro Genovese, Elena Provasi, Angelo Lombardo, Zulma 

Magnani, Pei-Qi Liu, Andreas Reik, Victoria Chu, David E. 

Paschon, Lei Zhang, Jurgen Kuball, Attilio Bondanza, Giulia 

Casorati, Fabio Ciceri, Claudio Bordignon, Philip D. Greenberg, 

Michael C. Holmes, Philip D. Gregory, Luigi Naldini, Chiara Bonini. 

499 

Primary Human CD8 + T Cells Engineered To Express a PD1- 

CD28 Chimeric Receptor Are Co-Stimulated through the 

Exploitation of Tumor Expressed PD-L1 

Megan E. Prosser, Christine E. Brown, Michael C. Jensen. 

500 

CD56-Specific T Cells Can Distinguish between Allogeneic 

and Autologous CD56 + Targets 

Denise L. Kellar, Sonny Ang, Simon Olivares, Helen Huls, 


501 

Chimeric γc-Cytokine Receptors That Support Engraftment 

of Human CD8 + Cytolytic T Lymphocytes 

Michelle R. Hunter, Vaidehi Mahadev, Christine E. Brown, 

Michael C. Jensen. 

502 

Novel Immunotherapy of Spontaneous Canine Malignant 

Melanoma: Intra Tumor Immune Stimulation and Long 

Term Survival with Adenovector CD40 Ligand Therapy 

Sara Westberg, Arian Sadeghi, Angelika Loskog, Thomas 

Segall, Olle Korsgren, Thomas Tötterman, Henrik von Euler. 

503 

Improved Expansion and Anti-Tumor Activity of Tumor- 

Specific CTLs Using a Transgenic Chimeric Cytokine 

Receptor 

Ann M. Leen, Usha Katari, Jacqueline Keirnan, Cliona M. 

Rooney, Malcolm K. Brenner, Juan F. Vera. 

504 

Co-Delivery of PSA and PSMA DNA Vaccines with 

Electroporation Induces Potent Immune Responses 

Bernadette Ferraro, Neil J. Cisper, Kendra T. Talbott, Lindsey 

Philipson-Weiner, Colleen E. Lucke, Amir S. Khan, Niranjan Y. 

Sardesai, David B. Weiner. 

505 

Clinical and Manufacturing Update of the FANG TM 

Autologous Tumor Cell Vaccine 

Phillip B. Maples, Padmasini Kumar, Yang Yu, Fabienne 

Norvell, Beena O. Pappen, Nicolas Tacquet, Alex W. Tong, 

Gladice Wallraven, Joseph Kuhn, Minal Barve, Cynthia Bedell, 

John Nemunaitis, Neil Senzer. 

506 

Highly Efficient Treatment of Ph + Acute Lymphoblastic 

Leukemia with a DNA Vaccine and 6-Mercaptopurine in Mice 

Yvonne Rott, Stefanie Arndt, Christina Marschke, Melchior 

Lauten, Manuel Schmidt, Burghardt Wittig, Katrin Kalies, 

Jürgen Westermann, Joachim Köchling. 

507 

Berry Extract Enhances a Leukemia Specific DNA Vaccine in 

the Treatment of Minimal Residual Disease in Mice with Ph + 

ALL 

Yvonne Rott, Melchior Lauten, Hendric Ungefroren, Michael 

Sagner, Manuel Schmidt, Burghardt Wittig, Joachim Köchling. 




4:40 PM - 6:40 PM 

Room: Hall 4B 

Cancer - Immunotherapy II 

508 

IL-21 Has an Anti-Apoptotic Effect on NK Cells during 

Activation 

Vladimir Senyukov, Cecele J. Denman, Laurence J. N. Cooper, 

Dean A. Lee. 

509 

Dose Escalation of Therapeutic High-Capacity, Gutless 

Adenoviral Vectors in the Naïve Rat Brain: Pre-Clinical 

Safety and Toxicity Evaluation as a Prelude to a Phase I 

Clinical Trial for Glioma 

A. K. M. G. Muhammad, Mariana Puntel, Weidong Xiong, 

Kyle Kelson, Alireza Salem, Kurt M. Kroeger, Chunyan Liu, 

Catherine Farrokhi, Liliana Lacayo, Robert N. Pechnick, Donna 

Palmer, Philip Ng, Pedro R. Lowenstein, Maria G. Castro. 

510 

Role of STAT3 Signaling in TK/Flt3L Gene Therapy Mediated 

Brain Tumor Regression 

Hikmat H. Assi, James Curtin, Chunyan Liu, Maria G. Castro, 

Pedro R. Lowenstein. 

511 

An Enhanced Non Viral Vector (EEV) Giving Improved 

Responses in Immunogene Cancer Treatment over 

Standard Plasmid Vectors 

Patrick F. Forde, Lindsay J. Hall, Marcel de Kruijf, Gerald C. 

O’Sullivan, Declan M. Soden. 

512 

A Novel Adjuvant Ling Zhi-8 Enhances the Efficacy of DNA 

Cancer Vaccine by Activating Dendritic Cells 

Chi-Chen Lin, Chia-Chiao Shih, Ching-Liang Chu. 

513 

Prostate Cancer Immunotherapy Using Bi-Specific Tumor- 

Reactive T Cells 

Robert C. Chan, Ceidy Sanchez, Anna Worth, Ann M. Leen, 

Malcolm K. Brenner, Ganesh Palapattu, Juan F. Vera. 


514 

microRNA-Sensitive Oncolytic Measles Viruses for Cancer- 

Specific Vector Tropism 

Mathias Felix Leber, Sascha Bossow, Vincent H. J. Leonard, 

Karim Zaoui, Christian Grossardt, Marie Frenzke, Tanner Miest, 

Stefanie Sawall, Roberto Cattaneo, Christof von Kalle, Guy 

Ungerechts. 

515 

Envelope-Chimeric Entry-Targeted Measles Virus Escapes 

Neutralization and Achieves Oncolysis 

Tanner S. Miest, Koon-Chu Yaiw, Marie Frenzke, Johanna 

Lampe, Andrew W. Hudacek, Christoph Springfeld, Veronika 

von Messling, Guy Ungerechts, Roberto Cattaneo. 

516 

A Novel Therapeutic Regime To Eradicate Established 

Tumors with an Effective Induction of Tumor-Specific 

Immunity 

James Tysome, Xiaozhu Li, Shengdian Wang, Pengju Wang, 

Dongling Gao, Rathi Gangeswaran, Dong Chen, Nick R. 

Lemoine, Yaohe Wang. 

517 

Armed and CD20-Retargeted Moraten Strain Measles 

Viruses for Combination Chemo- and Radiotherapy in Non- 

Hodgkin’s Lymphoma 

Tanner S. Miest, Marie Frenzke, Roberto Cattaneo. 

518 

Radiation Combined with Oncolytic Adenovirus Vector 

Suppresses Tumor Growth Better than Either Treatment 

Alone in the Syrian Hamster Model 

Brittany A. Young, Jacqueline F. Spencer, Karoly Toth, William 

S. M. Wold. 

519 

A Novel CDC25B Promoter Based Oncolytic Adenovirus 

Suppresses Tumor Growth in an Orthotopic Human 

Pancreatic Cancer Model 

Helga L. Weber, Gidekel Manuel, David T. Curiel, Eduardo G. 

Cafferata, Osvaldo L. Podhajcer. 

520 

The Effect of Combination Therapy of Oncolytic Virus 

hrR 3 and Antiangiogenic Therapy Bevacizumab in an 

Experimental Model of Pancreatic Carcinoma 

Tevfik T. Sahin, Hideki Kasuya, Akiyuki Kanzaki, Kazuo 

Yamamura, Suguru Yamada, Takashi Sugae, Gewen Tan, Yoko 

Nishikawa, Tsutomu Fujii, Shuji Nomoto, Hiroyuki Sugimoto, 

Akimasa Nakao. 

521 

Armed and Targeted Measles Virus for Virotherapy of 

Chemoresistant Pancreatic Cancer 

Christian Grossardt, Sascha Bossow, Achim Temme, Mathias F. 

Leber, Stefanie Sawall, Roberto Cattaneo, Christof von Kalle, 

Guy Ungerechts. 

522 

Tumor-Selective Suicide Gene Therapy by Transcriptionally 

Targeted Replicating Retrovirus Vectors 

Yi-Hui Lai, Chien-Kuo Tai. 


Friday, May 20


124 



4:40 PM - 6:40 PM 

Room: Hall 4B 


523 

BioKnife, a Urokinase-Targeted Oncolytic Sendai Virus, 

Eliminates Pleural Spread of Malignant Mesothelioma 

Yosuke Morodomi, Tokujiro Yano, Hiroaki Kinoh, Yui Harada, 

Satoru Saito, Tsukihisa Yoshida, Kensaku Ito, Yasunori Shikada, 

Riichiroh Maruyama, Kumi Yoshida, Yasuji Ueda, Mamoru 

Hasegawa, Yoshihiko Maehara, Yoshikazu Yonemitsu. 

524 

Complete and Sustained Tumor Regression of Human 

Malignant Mesothelioma Xenografts in Athymic Nude Mice 

Following Local Injection of Midkine Promoter-Regulated 

Oncolytic Adenovirus 

Shuji Kubo, Atsuko Tamamoto, Nobutaka Okamura, Yoshihiro 

Maeyama, Masatoshi Tagawa, Noriyuki Kasahara, Nobuyuki 

Terada, Haruki Okamura. 

525 

Adenoviral-Mediated Interferon-alpha Gene Therapy for 

Pancreatic Cancer 

Julia Davydova, Leonard Armstrong, Eric Brown, Joohee Han, 

Selwyn Vickers, Masato Yamamoto. 

526 

Evaluation of the Effect of Herpes Oncolytic Virus R3616 on 

the Host Immune Responses 

Kazuo Yamamura, Hideki Kasuya, Akiyuki Kanzaki, Tevfik 

Tolga Sahin, Tan Gewen, Suguru Yamada, Tsutomu Fujii, 

Hiroyuki Sugimoto, Shuji Nomoto, Shin Takeda, Akimasa 

Nakao. 

527 

RdB-VSV-G, a Vesicular Stomatitis Virus Glycoprotein 

Epitope-Incorporated Oncolytic Adenovirus Shows Marked 

Enhancement in Oncolysis and Suppression of Tumor 

Growth 

A.-Rum Yoon, Jaesung Kim, Renu Wadhwa, Sunil Kaul, Chae- 

Ok Yun. 

528 

Oncolytic Measles Virus Fully Retargeted to the Melanoma 

Surface Antigen HMWMAA 

Johanna K. Kaufmann, Sascha Bossow, Christian Groβardt, 

Stefanie Sawall, Jörg Kupsch, Guy Ungerechts, Dirk M. 

Nettelbeck. 

529 

Modification of the Early Gene Enhancer-Promoter 

Improves the Oncolytic Potency of Adenovirus 11 

Han Hsi Wong, Guozhong Jiang, Rathi Gangeswaran, Ming 

Yuan, Hexiao Wang, Vipul Bhakta, Heike Muller, Nick Lemoine, 

Yaohe Wang. 

530 

Retargeting Oncolytic Adenoviruses to Tumors Expressing 

c-Met 

Hany I. Sakr, Shilpa Bhatia, J. Michael Mathis. 



531 

Stanniocalcin-1 Derived from Multi Potent Stromal Cell 

Changes Cell Metabolism Dramatically, Decreases Reactive 

Oxygen Species Stress and Promotes Survival of Cancer 

Cells with Uncoupling Protein 2 Upregulation 

Shinya Ohkouchi, Gregory J. Block, Darwin J. Prockop, 

Toshihiro Nukiwa. 

532 

Neuropilin-1 Expressing Mononuclear Cells (NEMs), a 

Novel Population of Bone Marrow Cells Recruited by AAV2- 

Sema3A, Contributes to Vessel Normalization and Inhibits 

Tumor Growth 

Serena Zacchigna, Alessandro Carrer, Silvia Moimas, Lorena 

Zentilin, Mauro Giacca. 

533 

Examining the Role of CD44 in the Tumor Tropism of 

Multipotent Mesenchymal Stem Cell (MSC) for Cancer 

Microenvironments 

Erika L. Spaeth, Brian Toole, Ann Klopp, Michael Andreeff, 

Frank C. Marini. 

534 

Survivin Downregulation in Human Breast Cancer Cell 

Line by siRNA Delivery Using Hydrophobically Modified 

Aliphatic Polymers 

Hamidreza Montazeri Aliabadi, Breanne Landry, Parvin 

Mahdipoor, Hasan Uludag. 

535 

Bacterial Cell Therapy for Cancer 

Michelle Cronin, Sara A. Collins, Chwanrow Baban, Akihito 

Inagaki, Kei Hiraoka, Noriyuki Kasahara, Kevin Francis, 

Ali Akin, Cormac G. M. Gahan, Gerald C. O’Sullivan, Mark 

Tangney. 

536 

p16-Mediated Inhibition of Hypoxia-Induced Cancer Cell 

Migration 

Yi Lu, Liyuan Li.



4:40 PM - 6:40 PM 

Room: Hall 4B 


537 

Lentivirus-Mediated DR5 Agonistic Chimeric Antibody 

Expression for Cancer Gene Therapy 

Dexian Zheng, Juan Shi, Yanxin Liu, Shilian Liu. 

538 

Study of Radioisotope Uptake and Efflux in NIS Expressing 

Cells Goes High-Throughput 

Patrycja J. Lech, David Dingli, Stephen J. Russell. 



541 

293T Cells Transfected with a Degron-Conjugated Fusion 

Reporter Demonstrate Unexpected Increase in Reporter 

Activity 

Rehan S. Ali, Maximilian Diehn, Edward E. Graves, Ramasamy 

Paulmurugan. 

Gene Regulation II 

542 

MicroRNA-Based Transgene Regulation in the Retina 

Anna Manfredi, Marianthi Karali, Agostina Puppo, Elena 

Marrocco, Annagiusi Gargiulo, Enrico M. Surace, Sandro Banfi, 

Alberto Auricchio. 

543 

Creation of Structural Variations in the Human Genome 

Using Engineered Zinc Finger Nucleases 

Eunji Kim, Hyung Joo Lee, Jin-Soo Kim. 

544 

VEGF-A Zinc Finger Activator Is Neuroprotective in Rodent 

Preclinical Models of Stroke 

S. Kaye Spratt, Philippe M. D’Onofrio, Mark M. Magharious, 

Mahinthan Thayapararajah, Richard Surosky, Gary Lee, Martin 

Giedlin, Dale Ando, Michael Fehlings, Paulo D. Koeberle. 

545 

Regulation of AAV-Mediated Transgene Expression in 

Airway Epithelium In Vivo 

Maria P. Limberis, Melissa Fontana, ShuJen Chen, James M. 

Wilson. 

546 

Development and Characterization of a New Tet-ON AAV 

Vector for Tightly Controlled Transgene Expression 

Davide Gianni, Nancy H. Tran, Dimphna H. Meijer, Miguel 

Sena-Esteves. 

547 

Therapeutic microRNA Delivery Suppresses Mechanical 

Allodynia Induced by Mononeurpathic Pain in Rats 

Chung-Ren Lin, Kuan-Hung Chen, Chih-Hsien Wu, Yi-Shen Chen. 

548 

Differential Regulation of Multiple Transgenes by 

Alternative Splicing 

Eun-Young Choi, Xiaohuai Zhou, Richard J. Samulski. 

549 

Hypoxia-Specific Gene Expression System Using 

Oxygen Dependent Degradation Domain of Activating 

Transcription Factor 4 for Cancer Specific Gene Therapy 

Su Hee Cho, Hyun Ah Kim, Ji Hwan Park, Min Hyung Lee. 

550 

DNA Methylation and Gene Expression in hESCs Grown in 

Defined and Xeno-Free Culture Systems 

Joshua D. Tompkins, Christine A. Hall, Vincent C. Chen, 

Sylvana Couture, David Hsu, Larry A. Couture, Arthur D. Riggs. 

551 

Evaluation of the X-Protein Truncate Expression Potential 

from the WPRE Element in Alipogene Tiparvovec, an AAV- 

Based Gene Therapy Vector 

Jacek Lubelski, Florence Salmon, Betty Au, Larbi Afia, Andrew 

Bakker, Harald Petry. 



553 

Efficient Delivery of siRNA to Brain Capillary Endothelial 

Cells with Endogenous Lipoprotein In Vivo 

Hiroya Kuwahara, Kazutaka Nishina, Kie Yoshida, Tomoko 

Nishina, Wenying Piao, Hidehiro Mizusawa, Takanori Yokota. 

554 

Chemically Modified Antisense Oligonucleotides Can 

Direct Transcriptional Regulation of Gene Expression 

Stuart E. Knowling, Anne-Marie Turner, Kevin V. Morris. 

555 

AAV Vector-Mediated Efficient and Sustained miRNA 

Antagonism In Vivo for Studying miRNA Function and 

Treating Hyperlipidemia 

Jun Xie, Stefan Ameres, Randall Friedline, Jui-Hung Hung, 

Qing Xie, Li Zhong, Qin Su, Ran He, Mengxin Li, Xin Mu, 

Hongwei Zhang, Seemin Ahmed, Jennifer Broderick, 

Chengjian Li, Jsaon Kim, Zhiping Wen, Terence Flotte, Phillip 

Zamore, Guangping Gao. 


Friday, May 20


126 



4:40 PM - 6:40 PM 

Room: Hall 4B 


556 

Short Hairpin RNAs Targeted to the S Segment of Rift Valley 

Fever Virus Inhibits Viral Replication and Alleviates NSs- 

Induced Pathogenic Effects 

Tristan Scott, Janusz Paweska, Patrick Arbuthnot, Marco 

Weinberg. 

557 

Antisense Oligonucleotides Correct Aberrant PTS-Splicing: 

Therapeutic Potential To Treat Hyperphenylalaninemia and 

Brain Monoamine Neurotransmitter Deficiency 

Sandra Brasil, Hiu Man Viecelli, David Meili, Anahita Rassi, 

Lourdes R. Desviat, Belen Pérez, Magdalena Ugarte, Beat 

Thöny. 

558 

Mechanism of Uptaking Morpholino into Dystrophin- 

Deficient Muscle Fibers 

Yoshitsugu Aoki, Tetsuya Nagata, Toshifumi Yokota, Shinichi 

Takeda. 

559 

Induction of Endogenous Pluripotency Factor Expression in 

Human Mesenchymal Stem Cells by Small Activating RNAs 

Jon Voutila, Pål Sætrom, Paul Mintz, Guihua Sun, Jessica 

Alluin, John J. Rossi, Noriyuki Kasahara, Nagy A. Habib. 

560 

Bioreducible Polymer-Mediated siRNA Knockdown of 

BNIP3 in Primary Rat Ventricular Cardiomyocytes for the 

Prevention of Hypoxia-Induced Apoptosis 

Arlo N. McGinn, Tae Il Kim, David A. Bull, Sung Wan Kim. 

561 

Hepatitis C Virus Infection Down-Regulates MIR-29: Effects 

on Viral Fitness and Hepatic Stellate Cell Activation 

Sarmistha Bandyopadhyay, Robin C. Friedman, Rebecca 

T. Marquez, Kyle E. Brown, Christopher B. Burge, Warren N. 

Schmidt, Yulei Wang, Anton P. McCaffrey. 

562 

In Vivo Comparison of the Long-Term Efficacy of AAV 

Expressed ShRNA and MiRNA Targeting Apolipoprotein B100 

Piotr Maczuga, Annemart Koornneef, Richard van 

Logtenstein, Florie Borel, Harald Petry, Sander van Deventer, 

Pavlina Konstantinova. 

563 

Developing Use of Inosine-Containing siRNAs To Improve 

Hepatitis B Virus Silencing Specificity 

Justin Hean, Carol Crowther, Abdullah Ely, Piet Herdewijn, 

Patrick Arbuthnot. 

564 

Apolipoprotein B Knockdown by AAV-Delivered ShRNA 

Lowers Plasma Cholesterol in Mice 

Annemart Koornneef, Piotr Maczuga, Richard van 

Logtenstein, Florie Borel, Bas Blits, Tita Ritsema, Sander van 

Deventer, Harald Petry, Pavlina Konstantinova. 

565 

Assessment of Zwitterionic Lipids as Vectors for Nucleic 

Acid Delivery 

Juliane Nguyen, Colin L. Walsh, Francis C. Szoka. 

566 

Multidrug Resistance Transporters and miRNAs Expression: 

Changes in Hepatocellular Carcinoma 

Florie Borel, Harald Petry, Peter Jansen, Sander van Deventer, 

Pavlina Konstantinova. 

567 

Antisense Drug Development for Skipping Human 

Dystrophin Exons In Vitro and In Vivo Systematically 

Bo Wu, Ehsan Benrashid, Peijuan Lu, Caryn Cloer, Allen 

Zillmer, Mona Shaban, QiLong Lu. 

568 

Tracking Single Liposomes for Delivery of siRNA 

Matthew R. Tiffany, Francis C. Szoka. 

569 

RNAi-Mediated Gene Therapy of Human Diseases 

Annemart Koornneef, Piotr Maczuga, Florie Borel, 

Angelina Huseinovic, Peter Jansen, Harald Petry, Pavlina 

Konstantinova. 

570 

Silencing the Human Eag1 Potassium Channel in Glioma 

Cells by Using Short Interfering RNA 

Ludmylla C. Cunha, Ana Paula P. Faria, Bruno C. Gonzaga, 

Elaine Del Bel, Luis A. Pardo, Walter Stühmer, Ricardo 

Titze-de-Almeida. 


Improving the Specificity of RNAi-Based Therapeutics for 

Huntington’s Disease 

Ryan L. Boudreau, Jodi L. McBride, Ryan M. Spengler, Beverly 

L. Davidson. 




4:40 PM - 6:40 PM 

Room: Hall 4B 


571 

Characterization of Surface Markers and DNA Regulatory 

Gene Expression during Neutrophil Differentiation from 

Human Induced Pluripotent Stem Cells 

Hongmei Wang, Colin Sweeney, Harry Malech. 

572 

Clonal Cell Tracking Based on Multi-Colour RGB Marking 

with LeGO Vectors 

Kristoffer Weber, Michael Thomaschewski, Michael Warlich, 

Tassilo Volz, Kerstin Cornils, Birte Niebuhr, Maike Täger, Mark 

Lütgehetmann, Jörg-Matthias Pollok, Carol Stocking, Maura 

Dandri, Daniel Benten, Boris Fehse. 

573 

Enhancement of Tumor-Killing Activity of TRAIL-Expressing 

MSCs by Using Trichostatin A 

Ryosuke Uchibori, Hiroyuki Mizuguchi, Tomonori Tsukahara, 

Masashi Urabe, Hiroaki Mizukami, Akihiro Kume, Keiya 

Ozawa. 

574 

Reprogramming of Adult Human Extrahepatic Biliary Cells 

into Functional Pancreatic Beta Cells 

Feorillo Galivo, Raymond Hickey, Kathryn Schubert, Rohan 

Manohar, Eric Lagasse, Markus Grompe. 

575 

iPS Cell Formation Invokes Shared Biological and 

Transcriptome Changes with Tumorigenesis 

John Riggs, Paul S. Knoepfler. 

576 

Genetic Modifications at Safe Harbor Loci in Hematopoietic 

Stem Cells for Gene Therapy 

Laurent Poirot, Roman Galetto, Frédéric Lemaire, Frédéric 

Cédrone, Sylvain Arnoud, Agnès Gouble, Carole Desseaux, 

Julianne Smith, Frédéric Pâques. 

577 

Efficient Generation of Vector/Transgene Free Human 

Induced Pluripotent Stem Cells from Intractable Disease 

Patients Using Non-Integrating Sendai Virus Vectors 

Noemi Fusaki, Hiroshi Ban, Toshiaki Tabata, Akihiro Iida, 

Mamoru Hasegawa, Hironobu Ihn, Takumi Era. 

578 

Towards Targeted Transgene Integration in Induced 

Pluripotent Stem Cells 

Ruan van Rensburg, Oleg Denisenko, Karol Bomsztyk, Ines 

Beyer, ZongYi Li, Andre Lieber. 

579 

Scalable Expansion of Undifferentiated Human Embryonic 

Stem Cells in Serum-Free and Defined Suspension Culture 

Vincent C. Chen, Sylvana Couture, Jingjing Ye, Joshua 

Tompkins, David Hsu, Melissa Carpenter, Robin 

Wesselschmidt, Larry Couture. 

580 

CXCR1 Mediated Migratory Capacity of Human Umbilical 

Cord Blood-Derived Mesenchymal Stem Cells toward 

Gliomas 

Seong Muk Kim, Dal-Soo Kim, Chang Hyun Jeong, Sin-Soo 

Jeun, Wonil Oh, Jong Wook Chang. 

581 

Engraftment and Fate of Endothelial Progenitor Cells 

Transplanted to Rat Hindlimb Ischemia Monitored by a 

Novel MRI Cell Tracking System 

Tetsuji Yamaoka, Carlos G. Agdelo, Hidehiro Iida, Yoichi 

Tachibana. 

582 

Ultrasound Gene Delivery to Mesenchymal Stem Cells: 

Targeting Tumor Therapy 

Tom Haber, Marcelle Machluf. 

583 

Universal Stem Cell Gene Therapy Platform: Combining 

Ex Vivo Strategies and Injectable Tissue/Organ-Specific 

Extracellular Matrix (ECM) Hydrogels 

Roger Bertolotti. 

584 

Regenerative Cell Therapy for Liver Diseases with Skin 

Adipose Tissues-Derived Stem Cells 

Sin-Ting Wang, Chi-Chen Lin. 


585 

Scalable Manufacturing of Recombinant Adeno-Associated 

Virus Using Suspension HEK293 Cells 

Joshua C. Grieger, Stephen M. Soltys, Joy R. Burleyson, 

Richard J. Samulski. 

586 

Use of the Counterflow Centrifugal Elutriation in the 

Preparation of Apheresis Products for Use in Cell Therapy 

Applications 

Chy-Anh T. Tran, Monica Coronado, Agnes Gardner, Lijing Li, 

Anitha Rao, Lan-Feng Cao, Qing Liu, John A. Zaia, David L. 

DiGiusto. 


Friday, May 20


128 



4:40 PM - 6:40 PM 

Room: Hall 4B 


587 

Alternative Vector Titration Methods for scAAV Vectors 

Eliminate Systemic Errors Caused by Template Self- 

Annealing during qPCR Thermocycling 

Paolo Fagone, Susan Sleep, James A. Allay, J. Fraser Wright, 

Amit C. Nathwani, Andrew M. Davidoff, Arthur W. Nienhuis, 

John T. Gray. 

588 

PK-7 and RD2-MolPack-Chim3.14, Two Packaging Cell 

Clones for Semi-Stable and Stable Production of HIV-Based 

Lentiviral Vectors 

Anna Stornaiuolo, Bianca Piovani, Francesca Salvatori, 

Eleonora Zucchelli, Claudio Bordignon, Raul Ziliotto, Gian- 

Paolo Rizzardi, Chiara Bovolenta. 

589 

Evaluation of Biopotency of rHIV Lentiviral Vectors 

Produced for Ex Vivo Hematopoietic Gene Therapy 

Sabine Charrier, Otto-Wilhelm Merten, Frédéric Barnay- 

Toutain, Armelle Viornery, Stéphanie Bucher-Laurent, Muriel 

Audit, Mehdi Gasmi, Anne Galy. 

590 

Using Pulmozyme DNase Treatment as an Alternative to 

Benzonase for Lentiviral Vector Supernatant Production 

Aaron Shaw, Daniela Bischof, Aparna Jasti, Aaron Ernstberger, 

Troy Hawkins, Kenneth Cornetta. 

591 

Large Scale Production of Suspension Cells for Clinical 

Application Using a Novel Cell Bioreactor 

Juan F. Vera, Lara Brenner, Natalia Lapteva, Ann M. Leen, John 

Wilson, Helen E. Heslop, Cliona M. Rooney. 

592 

Manufacturing Complex Recombinant Biopharmaceuticals 

Using a Lentivector-Based Production System 

H. Trent Spencer, Gabriela Denning, Richard E. Gautney, Kyle 

Harris, Andre J. Roy, Lajos Barayni, Boro Dropulic, Christopher 

B. Doering. 

593 

SFM rHSV-Based Production of rAAV Vectors in Suspension 

BHK Cells 

David R. Knop, Darby L. Thomas, Charlotte Butts. 

594 

Fully-Automated Cell Selection, Cultivation and Genetic 

Modification in a Closed Environment for the Flexible 

Manufacturing of Cellular Products 

Ian C. D. Johnston, Martin Biehl, Melanie Fahrendorff, Volker 

Huppert, Stefan Miltenyi. 

595 

Measurement of Viral Titer by Fluorescence Nanoparticle 

Tracking Analysis 

Andrew Malloy, Duncan A. Griffiths, Patrick Hole, Bob Carr. 

596 

Where Human Gene Transfer Is Illegal: Local Regulation of 

rDNA Clinical Research 

Jan P. Vleck, Gary M. Johnson, Ethan Mascoop. 

597 

Challenges in the Production of Large and Complex 

Plasmid Vectors for Gene Therapy 

Ying Cai, Stephen Rodriguez, Luke Clifford, Henry L. Hebel. 



889 

Impact of Long-Term shRNA Expression on Hepatic Gene 

Profiles 

Miwon Ahn, Scott R. Witting, Rafaela Ruiz, Romil Saxena, 

Nuria Morral. 


891 

Phase II Trial of Intravenous Administration of Reolysin 

(Reovirus Serotype-3-Dearing Strain) in Patients with 

Metastatic Melanoma 

E Galanis, SN Markovic, V Suman, G Nuovo, R Vile, M Coffey, G 

Linette, W Maples, J Zwiebel, K Kendra. 

892 

A Potential microRNA-Based Therapy for Pancreatic Ductal 

Adenocarcinoma Using AAV-Mediated Delivery 

Janaiah Kota, Raghu R. Chivukula, Oliver A. Kent, Kim M. 

Shontz, Anirban Maitra, K. Reed Clark, Jerry R. Mendell, 

Joshua T. Mendell. 

893 

Measles Virus Glycoprotein-Pseudotyped Lentiviral 

Vector-Mediated Gene Transfer into Quiescent T and B 

Lymphocytes Requires Binding to both SLAM and CD46 

Entry Receptors 

Cecilia Frecha, Camille Lévy, Caroline Costa, Didier Nègre, 

Fouzia Amirache, Robin Buckland, Steven J Russell, François- 

Loïc Cosset, Els Verhoeyen.



4:40 PM - 6:40 PM 

Room: Hall 4B 


894 

Adenoviral Vector Codifying for hBcl-2 Improves In Vivo 

Muscle Regeneration. 

Francisco Martínez-F, Araceli Barrera-L, Erendira Estrada-V, 

Hugo Sandoval-Z, Hilda Villegas-C, Catalina Machuca-R, 

David T Curiel, JA Madinaveitia-V. 

895 

Betamethasone Delays the egr-1 Promoter Response 

at UV Induction in Human Primary Dermal Fibroblasts 

Transduced with Ad-egr1-Luc 

Francisco Martínez-F, Araceli Barrera-L, JA Madinaveitia-V, 

Erendira Estrada-V, Hugo Sandoval-Z, Hilda Villegas-C, 

Catalina Machuca-R, David T. Curiel, K Sakamoto. 

896 

Optimization of DNA to siRNA Ratio in SNS01 – an eIF5A- 

Based Gene Therapy Nanoparticle Designed for the 

Treatment of Multiple Myeloma 

C. Taylor, Z. Liu, B. Ye, T. Tang, J. Thompson, R. Dondero. 

897 

Development and Testing of a Novel Gene Therapy 

Strategy Using Secreted Proteins 

Alexander Falkenhagen, Jimmy Chen, Masoud Ameli, Sabah 

Asad, Stanley E Read, Sadhna Joshi. 

898 

HB-EGF/HGF Hepatic Gene Therapy Effectively Inhibits 

Bile Duct Ligated Cholestatic Liver Injury in Mice in Their 

Different Therapeutic Modes 

Ken-ichiro Kosai, Kouichi Sakamoto, Nign Cin Khai, Yuqing 

Wang, Rie Maezono, Kiyonori Tanoue, Hideo Takamatsu, 

Hiroshi Matsufuji. 

899 

Local and Systemic Anti-Tumor Immunity is Induced 

by Rheoswitch Regulated IL-12 Production after Intra- 

Tumoral Injection of Adenovirus Vector as well as Vector- 

Transduced Dendritic Cells 

Ronald B. Herberman, Meixia Bi, Mario Moreno, Lisa 

Butterfield, Mary Jo Buffo, Mark Thornton, Kimberly 

Shafer-Weaver. 

900 

Defining Binding Sites of the Homing Endonuclease I-CreI 

in the Human Genome by ChIP-seq 

Stefan Pellenz, Hui Li , Raymond J Monnat Jr.. 

901 

rAAV1 Vector-Mediated Expression of Tafazzin in Patient 

Fibroblasts and Murine Model of Barth Syndrome 

MS Soustek, DJ Falk, CS Mah, AS Lewin, BJ Byrne. 

902 

Use of Lentiviral Vectors to Sensitize Pancreatic Cancer 

Cells to Chemotherapy 

Adeline Pointreau, Flavie Sicard, Louis Buscail, Pierre 

Cordelier. 

903 

Generation of an HLA-negative K562 Clone as Proof-of- 

Principle for Targeting of HLA-C by a Novel Zinc-Finger 

Nuclease 

Howard Rosoff, Vladimir Senyukov, Hiroki Torikai, Andreas 

Reik, Nick Littman, Philip D. Gregory, Michael C. Holmes. 

904 

Chitosan Structure Related to Transfection Efficiency and 

Colloidal Stability 

Marc Lavertu, Surendra Nimesh, Sotcheadt Sim, Marc 

Thibault, Michael D Buschmann. 

905 

Effect of a DNA Nuclear Targeting Sequence on the Nuclear 

Translocation Efficiency of a Suicide Gene Coding Plasmid 

in Small Cell Lung Cancer 

Frederik Cramer, Camilla Laulund Christensen, David A. Dean, 

Hans Skovgaard Poulsen. 

906 

Targeting Regulatory T Cells in Cancer By Selective Delivery 

of RNA Interference 

William L Byrne, Patrick F Forde, Gerald C O’Sullivan. 

907 

Differences in Retrograde Axonal Transport of AAV6 

Vectors 

Brooke R. Snyder, Deirdre M. O’Connor, Jeremiah W. Huang, 

Eric T. Quach, Eleanor M. Donnelly, Chalonda R. Handy, 

Nicholas M. Boulis. 

908 

Adeno-Associated Virus Mediated Gene Targeting by 

Homologous Recombination in Human Somatic Cell Lines 

Rob Howes, Chris Torrance. 

909 

Chitosan-Graft-Spermine as a Gene Carrier for Lung Cancer 


Hu-Lin Jiang, Seong-Ho Hong, You-Kyoung Kim, Ji-Young 

Shin, Ji-Eun Kim, Kyeong-Nam Yu, Seung-Hee Chang, Chong- 

Su Cho, Myung-Haing Cho. 

910 

Gene Synthesis: A Cost-effective Alternative to Traditional 

Molecular Cloning 

Marc Schwartz, Hanson Lo, Jason Zhou, Ping Yang, Amy Liao. 


Friday, May 20


130 

Abstract Directory Saturday, May 21, 2011 


Clinical Gene & Cell Therapy 

10:15 AM - 12:15 PM 

Room: 606-607 

598 10:15 AM 

A Gene Therapy Approach to HIV: Adoptive Transfer of Zinc 

Finger Nuclease (ZFN) Modified Autologous CD4 T-Cells 

to Aviremic HIV-Infected Subjects with Suboptimal CD4 

Counts (200-500 Cells/mm3) 

Shelley Wang, Jay Lalezari, Ronald Mitsuyasu, Steven Deeks, 

Winson Tang, Gary Lee, Michael Holmes, Phillip Gregory, 

Marty Giedlin, Dale Ando. 

599 10:30 AM 

Clinical Trial Results: Intralesional Injection of a Tumor 

Selective Oncolytic Vaccinia Virus 

Herbert J. Zeh, Mark O’Malley, Heather Jones, David H. Kirn, 

Moon Anne, Hwang H. Tae, David L. Bartlett. 

600 10:45 AM 

Safety and Efficacy of Re-Administration of AAV2.hRPE65v2 

in Subjects with Leber Congenital Blindness Due to RPE65 

Mutations 

Jean Bennett, Albert M. Maguire, Federico Mingozzi, Eric A. 

Pierce, Daniel C. Chung, Jeannette Bennicelli, Junwei Sun, 

J. Frasier Wright, Kathleen Marshall, Jennifer M. Wellman, 

Katherine A. High. 

601 11:00 AM 

CUPID – A Phase 2 Trial of Intracoronary Gene Therapy 

of Sarcoplasmic Reticulium CA2+ ATPase (SERCA2a) in 

Patients with Advanced Heart Failure 

Krisztina M. Zsebo, Mariell Jessup, Barry Greenberg, Donna 

Mancini, Daniel Pauly, Roger Hajjar, On Behalf of the CUPID 

Investigators. 

602 11:15 AM 

Dose-Dependent Activation of Capsid-Specific T Cells after 

AAV Serotype 8 Vector Administration in a Clinical Study 

for Hemophilia B 

E. Basner-Tschakarjan, F. Mingozzi, Y. Chen, A. C. Nathwani, 

E. G. D. Tuddenham, C. Rosales, J. McIntosh, A. Riddell, P. 

Rustagi, B. Glader, M. A. Kay, J. Allay, J. Coleman, S. Sleep, J. 

Gray, U. Reiss, A. W. Nienhuis, A. M. Davidoff, K. A. High. 

603 11:30 AM 

ProSavin® a Gene Therapy Approach for the Treatment of 

Parkinson Disease: Phase I Clinical Trial Update 

Kyriacos Mitrophanous, Bechir Jarraya, Scott Ralph, Helene 

Lepetit, James Miskin, Jean-Marc Gurruchaga, Gilles Fenelon, 

Sabrina Boulet, Caroline Jan, Gilles Bonvento, Pierre Brugiere, 

Susan Kingsman, Stuart Naylor, Philippe Hantraye, Philippe 

Remy, Stephane Palfi. 

604 11:45 AM 

Gene Therapy with Lentiviral Vector Transduced CD34 + 

Cells for the Treatment of Wiskott-Aldrich Syndrome 

Samantha Scaramuzza, Francesca Ferrua, Maria Carmina 

Castiello, Luca Biasco, Marita Bosticardo, Costanza Evangelio, 

Maria Pia Cicalese, Miriam Casiraghi, Anna Ripamonti, 

Stefania Giannelli, Monica Salomoni, Andrea Finocchi, 

Alessandra Biffi, Fabio Ciceri, Anna Villa, Maria Grazia 

Roncarolo, Luigi Naldini, Alessandro Aiuti. 

605 12:00 PM 

The Infusion of Suicide Gene-Modified Donor T Cells 

after Hematopoietic Stem Cell Transplantation Prompts 

Thymic Renewal in Adult Patients by an IL-7 Dependent 

Mechanism 

Luca Vago, Giacomo Oliveira, Maddalena Noviello, Corrado 

Soldati, Domenico Ghio, Immacolata Brigida, Alessandro 

Aiuti, Maria Tersa Lupo Stanghellini, Jacopo Peccatori, Attilio 

Bondanza, Alessandro Del Maschio, Claudio Bordignon, Fabio 

Ciceri, Chiara Bonini. 




10:15 AM - 12:15 PM 

Room: 615-617 

606 10:15 AM 

Assessing the Impact of Lentiviral Vector Integration on 

Splicing of Cellular Genes at the Genome-Wide Level 

Stefania Merella, Jacopo Sgualdino, Daniela Cesana, Fabrizio 

Benedicenti, Simone Leo, Gianluigi Zanetti, Luigi Naldini, 

Eugenio Montini. 

607 10:30 AM 

Read-Through/Splicing-Capture Mechanism Is the Major 

Determinant of Enhancer Genotoxicity of Vectors with 

Active LTRs 

Daniela Cesana, Marco Ranzani, Cynthia Bartholomae, 

Monica Volpin, Stefania Merella, Fabrizio Benedicenti, Lucia 

Sergi Sergi, Christof von Kalle, Manfred Schmidt, Luigi 

Naldini, Eugenio Montini. 

608 10:45 AM 

Cell Surface Heparan Sulfate Proteoglycan (HSPG) Is a 

Receptor for Foamy Virus 

Md Nasimuzzaman, Derek A. Persons. 

609 11:00 AM 

Gas6 Mediates Lentiviral Vector Entry through Apoptotic 

Mimicry by Bridging Virion Envelope Phosphatidylserine to 

Axl 

Kouki Morizono, Yiming Xie, Tove Olafsen, Benhur Lee, Asim 

Dasgupta, Anna M. Wu, Irvin S. Y. Chen.




10:15 AM - 12:15 PM 

Room: 615-617 

610 11:15 AM 

An Integrated Approach To Discover New Liver Cancer Genes 

and Test the Genotoxicity of Vectors for Liver Gene Therapy 

Marco Ranzani, Alessio Cantore, Daniela Cesana, Cynthia 

Bartholomae, Francesca Sanvito, Mauro Pala, Fabrizio 

Benedicenti, Monica Volpin, Pierangela Gallina, Lucia Sergi Sergi, 

Alessandro Bulfone, Claudio Doglioni, Christof von Kalle, Manfred 

Schmidt, Giovanni Tonon, Luigi Naldini, Eugenio Montini. 

611 11:30 AM 

Lentiviral Vector Common Integration Sites in the ALD 

and MLD Clinical Trials and in a Preclinical Model Reflect a 

Benign Integration Bias and Not Oncogenic Selection 

Alessandra Biffi, Cynthia C. Bartolomae, Daniela Cesana, Natalie 

Cartier, Marco Ranzani, Martina Cesani, Fabrizio Benedicenti, 

Tiziana Plati, Merella Stefania, Alessia Capotondo, Jacopo 

Sgualdino, Patrick Aubourg, Gianluigi Zanetti, Christof von 

Kalle, Manfred Schmidt, Luigi Naldini, Eugenio Montini. 

612 11:45 AM 

Defining the Lentiviral Integrome in Human Hematopoietic 


Alessandra Recchia, Claudia Cattoglio, Danilo Pellin, Ermanno 

Rizzi, Giorgio Corti, Clelia Di Serio, Nirav Malani, Frederick 

Bushman, Gianluca De Bellis, Fulvio Mavilio. 

613 12:00 PM 

Foamy Virus Vectors with Strong Viral Enhancers Display 

Low In Vitro Immortalization Potential in Primary Murine 

Hematopoietic Progenitor Cells 

Paritha I. Arumugam, Danielle L. Lynn, Johannes C. M. van 

der Loo, Thomas R. Bauer, Dennis D. Hickstein, David Russell, 

Punam Malik. 



10:15 AM - 12:15 PM 

Room: 6A 

614 10:15 AM 

High-Throughput Genome-Wide siRNA Screening Unravels 

Cellular Factors Critical for AAV Transduction 

Miguel Mano, Rudy Ippodrino, Jasmina Lovric, Lorena 

Zentilin, Mauro Giacca. 

615 10:30 AM 

Enhanced Transgene Expression and Site-Specific 

Integration of Adeno-Associated Virus Depends on 

Methylation Status of the Target Cell 

Diptiman Chanda, Jonathan A. Hensel, Jerome T. Higgs, Rajat 

Grover, Niroop Kaza, Selvarangan Ponnazhagan. 

616 10:45 AM 

rAAV Hairpin Structure Does Not Contribute to 

Chromosomal Integration 

Marcela P. Cataldi, Douglas M. McCarty. 

617 11:00 AM 

Assessment of Oncogenic Insertional Activation Potential 

from rAAV Vector 

Lucia E. Rosas, Jessica L. Grieves, Douglas M. McCarty. 

618 11:15 AM 

Investigating the Axonal Transport of AAV Serotype 9 in a 

Microfluidic System 

Michael J. Castle, Eran Perlson, Erika L. F. Holzbaur, John H. 

Wolfe. 

619 11:30 AM 

AAV Vector-Mediated Activation of Canonical and 

Alternative NF-κB Pathways In Vivo: Implications for Innate 

and Adaptive Immune Responses and Gene Therapy 

Giridhara R. Jayandharan, George V. Aslanidi, Ashley T. 

Martino, Stephan C. Jahn, George Q. Perrin, Roland W. 

Herzog, Arun Srivastava. 

621 11:45 PM 

Assessment of Genotoxic Potential of Different AAV 

Serotype Vectors in Liver-Directed Gene Transfer 

Li Zhong, Nirav Malani, Mengxin Li, Troy Brady, Jun Xie, Peter 

Bell, Haven Jones, James M. Wilson, Frederick D. Bushman, 

Guangping Gao. 

620 12:00 AM 

“Fragmented” AAV Vectors Rely on a Novel Homologous 

Recombination Repair Mechanism for Efficient Large Gene 

Delivery In Vivo 

Matthew L. Hirsch, Chengwen Li, R. J. Samulski. 



10:15 AM - 12:15 PM 

Room: 611-612 

629 10:15 AM 

Sustaining Cardiac Expression of Adenovirus Delivered 

Genes with a Dexamethasone Releasing Hydrogel 

Karen Kadner, Sharma Vinod, Deon Bezuidenhout, Peter Zilla, 

Neil Davies. 

623 10:30 AM 

Effective Gene Transfer Using Microbubble-Assisted 

Ultrasound Therapy in Canine Livers 

Misty L. Noble, Andrew A. Brayman, Christian S. Kuhr, Scott S. 

Graves, George W. Keilman, Liping Chen, Keith R. Loeb, Rainer 

F. Strob, Carol H. Miao. 


Saturday, May 21


132 




10:15 AM - 12:15 PM 

Room: 611-612 

624 10:45 AM 

Localized Gene Modification of Muslce Tissue Using 

Autologous Fat Grafts as a Vehicle for Viral Vector Delivery 

Ergun Kocak, Katherine H. Carruthers, Matthew J. During. 

625 11:00 AM 

Optimization of High Intensity Therapeutic Ultrasound and 

Microbubbles for Gene Delivery into Rat Liver 

Shuxian Song, Misty L. Noble, Samuel Sun, Liping Chen, 

Andrew A. Brayman, Carol H. Miao. 

626 11:15 AM 

Gene Delivery Using a Novel Physical Mode of Transfection 

Based on Electrospray 

Michael Maguire, Heather Kavanagh, Eoin Judge, Natasha 

McCormack, James Egan, Shirley O’Dea. 

627 11:30 AM 

Optimization of Image-Guided Hydrodynamic Gene 

Delivery to Liver of Large Animals 

Kenya Kamimura, Takeshi Suda, Tsutomu Kanefuji, Guisheng 

Zhang, Dexi Liu. 

439 11:45 AM (MOVED FROM POSTER SESSION II) 

Genetic Electrotransfer Immunization for the Identification 

of Functionally Important Epitopes: The Example of 

VAR2CSA in Placental Adhesion of Plasmodium Falciparum 

Infected Erythrocytes 

S. Gnidehou, P. Bigey, J. Doritchamou, M. Quiviger, F. Viwami, 

A. Couturier, A. Salanti, Daniel Scherman, P. Deloron, N. Tuikue 

Ndam. 

622 12:00 PM 

High-Resolution, Overlapping Deposition of Multiple 

Plasmid DNA Species on a Cell Culture Substrate for 

Patterned Electroporation to a Cell Monolayer 

Marven Lamarre, Howard H. Lou, Woo Y. Lee, Philip L. Leopold. 


Gene Targeting 

10:15 AM - 12:15 PM 

Room: 608-609 

630 10:15 AM 

PhiC31 Integrase Fusion Proteins: Targeted Insertion 

towards Specific Genomic Sites 

Nadja Noske, Nina Harms, Anja Ehrhardt. 

631 10:30 AM 

Sustainable Gene Transfer by Selection of Genomic Target 

Site and In Situ Tailoring of Cassette Design in Human 

Lymphocytes and Stem Cells 

Angelo Lombardo, Daniela Cesana, Pietro Genovese, Daniele 

Colombo, Bruno Di Stefano, Elena Provasi, Margherita Neri, 

Zulma Magnani, Michael C. Holmes, Philip D. Gregory, Angela 

Gritti, Vania Broccoli, Chiara Bonini, Luigi Naldini. 

632 10:45 AM 

Genome-Wide Determination of Induced DNA Double- 

Strand Breaks Reveals High Specificity of Zinc Finger 

Nucleases 

Richard Gabriel, Angelo Lombardo, Anne Arens, Jeffrey C. 

Miller, Pietro Genovese, Christine Kaeppel, Ali Nowrouzi, 

Cynthia C. Bartholomae, Jianbin Wang, Geoffrey Friedman, 

Michael C. Holmes, Philip D. Gregory, Hanno Glimm, Manfred 

Schmidt, Luigi Naldini, Christof von Kalle. 

633 11:00 AM 

Targeted Gene Integration in Human Epidermal Stem 

Cells by Zinc-Finger Nuclease-Mediated Homologous 

Recombination 

Annarita Miccio, Angelo Lombardo, Andrea Coluccio, 

Francesca Miselli, Michael Holmes, Philip D. Gregory, Luigi 

Naldini, Alessandra Recchia, Fulvio Mavilio. 

634 11:15 AM 

Zinc-Finger Nuclease-Mediated Gene Correction Using 

Single AAV Vector Transduction and Enhancement by FDA 

Approved Drugs 

Brian L. Ellis, Matthew L. Hirsch, Jenny Barker, Richard J. 

Samulski, Matthew H. Porteus. 

635 11:30 AM 

Improved Technology for Estimating the Abundance of 

Gene Corrected Clones from Integration Site Data 

Troy L. Brady, Shoshannah L. Roth, Nirav Malani, Frederic D. 

Bushman. 

636 11:45 AM 

Using a Novel Negative Selection Based on shRNA Strategy 

To Enrich for Homologous Recombinants 

Feng Gu, Roli Hirata, David Russell. 

637 12:00 PM 

Evaluation of a Reporter System for Site-Specific I-SceI- 

Mediated Genome Editing in Canine Hematopoietic Stem Cells 

Nina M. Muñoz, Brian C. Beard, Byoung Y. Ryu, Grant D. 

Trobridge, Andrew M. Scharenberg, Hans-Peter Kiem. 





10:15 AM - 12:15 PM 

Room: 602-604 

638 10:15 AM 

Non-Viral Delivery of STICKY-SIRNA Targeting the Cell 

Cycle Inhibits Lung Tumor Metastasis 

Anne-Laure Bolcato-Bellemin, Marie-Elise Bonnet, Jean-Paul 

Behr, Patrick Erbacher. 

639 10:30 AM 

Early Efficacy Study of Ad-p53 in Combination with 

Gemcitabine and Intraperitoneal Cisplatin Plus Regional 

Thermotherapy in Advanced Pancreatic Cancer with 

Ascites 

Yuan Qin, Dong Ren, Yufei Fan, Xiaolin Liu, Dinggang Li. 

640 10:45 AM 

Imaging and Treatment of Pancreatic Cancer Using an 

Oncolytic Vaccinia Virus Carrying the Human Sodium 

Iodide Symporter 

Dana Haddad, Nanhai Chen, Qian Zhang, Chun-Hao Chen, 

Yong A. Yu, Lorena Gonzalez, Jochen Stritzker, Jason Aguilar, 

Susanne G. Carpenter, Joshua Carson, Joyce Au, Arjun Mittra, 

Mithat Gonen, Pat B. Zanzonico, Aladar A. Szalay, Yuman Fong. 

641 11:00 AM 

TK.007 Mediates Superior Killing Efficiency and Bystander 

Effect in Cancer Suicide Gene Therapy 

Ellen Preuss, Alexander Muik, Kristoffer Weber, Jürgen Otte, 

Dorothee von Laer, Boris Fehse. 

642 11:15 AM 

Human Antrum Mucosal Protein 18 Gene Transfer for the 

Prevention of Radiation-Induced Oral Mucositis in Mouse 

Model 

Changyu Zheng, Ana P. Cotrim, Abraham N. Sunshine, 

Fernando Velasquez, Anastasia Sowers, James B. Mitchell, 

Bruce J. Baum. 

643 11:30 AM 

Combined, but Not Individual, Adenoviral Delivery of 

p19Arf and Interfon-beta Induces Massive Cell Death in a 

Mouse Model of Melanoma 

Bryan E. Strauss, Christian A. Merkel. 

644 11:45 AM 

Imaging Nitroreductase (nfnB) Reporter Gene Expression in 

Living Animals 

Thillai V. Sekar, Srabani Bhaumik, Jeannette Depuy, June 

Klimash, Ramasamy Paulmurugan. 

645 12:00 PM 

Dual-Therapeutic Reporter Genes Fusion for Enhanced 

Cancer Gene Therapy and Imaging 

Ramasamy Paulmurugan, Thillai V. Sekar, Srabani Bhaumik. 



10:15 AM - 12:15 PM 

Room: 618-620 

646 10:15 AM 

Dramatic Phenotypic Improvement after Adeno-Associated 

Virus Gene Therapy in a Feline Model of Sandhoff Disease 

Aime K. Johnson, Allison M. Bradbury, Julian Arthur, Victoria 

J. Jones, Misako Hwang, Stanley G. Leroy, Nancy E. Morrison, 

Jacob A. Johnson, Peter W. Christopherson, Nancy R. Cox, 

Henry J. Baker, Thomas N. Seyfried, Miguel Sena-Esteves, 

Douglas R. Martin. 

647 10:30 AM 

Intracarotid Delivery of AAV9 Vector Is a Powerful Method 

for Gene Delivery to the Primate Brain 

Krystof Bankiewicz, Ernesto Aguilar Salegio, John Bringas, 

Adrain Kells, Kevin Foust, John Forsayeth, Brian Kaspar. 

648 10:45 AM 

Zinc Finger Nuclease-Mediated Editing of Dominant 

Retinal Mutations in Mice 

Ivette M. Sandoval, Brandee A. Price, Fung Chan, Alecia K. 

Gross, David L. Simons, Jiuli Zhang, Steve Zhang, David E. 

Paschon, William W. Hauswirth, Matthew H. Porteus, Philip D. 

Gregory, Theodore G. Wensel, John H. Wilson. 

649 11:00 AM 

rAAV-Mediated, Systemically Delivered and miRNA- 

Regulated CNS Gene Transfer Effectively Correct Metabolic 

and Psychomotor Defect, Alleviate Neuropathology, and 

Prolong Survival of ASPA -/- Mice with Canvan Disease 

Seemin Ahmed, Sylvia Szucs, Hongwei Zhang, Qin Su, Ran 

He, Miguel Sena-Esteves, Terence Flotte, Reuben Matalon, 

Guangping Gao. 

650 11:15 AM 

Suppression of HTT in the Rhesus Macaque: Behavioral, 

Histological and Molecular Analysis of RNAi as a Therapy 

for Huntington’s Disease 

Jodi L. McBride, Mark R. Pitzer, Ryan L. Boudreau, Brett D. 

Dufour, Sergio R. Ojeda, Beverly L. Davidson. 

651 11:30 AM 

Robust Motor Neuron Transduction Following Intrathecal 

Delivery of AAV9.GFP to Pigs 

Thais Federici, Jason S. Taub, Steven S. Gray, Stacey Foti, Josh 

Grieger, Chalonda R. Handy, Eleanor M. Donnelly, R. Jude 

Samulski, Nicholas M. Boulis. 


Saturday, May 21


134 




10:15 AM - 12:15 PM 

Room: 618-620 

652 11:45 AM 

Passive Immunization with an AAV Vector Expressing 

an Anti-Cocaine Antibody Shields the Brain from 

Systematically Administered Cocaine, Suppressing 

Cocaine-Induced Hyperlocomotion 

Martin L. Hicks, Jonathan B. Rosenberg, Bishnu P. De, 

Esther Z. Frenk, Odelya E. Pagovich, Jianping Qiu, Stephen 

M. Kaminsky, Neil R. Hackett, Lisa M. Eubanks, Kim Janda, 

Sunmee Wee, George Koob, Ronald G. Crystal. 

653 12:00 PM 

Persistent Suppression of Ocular Neovascularization with 

a Single Intravitreal Administration of AAVrh.10BevMab, 

an Adeno-Associated Viral Gene Transfer Vector Coding for 

Bevacizumab 

Yanxiong Mao, Szilard Kiss, Julie L. Boyer, Andrew Carbone, 

Jason G. Mezey, Stephen M. Kaminsky, Donald J. D’Amico, 

Ronald G. Crystal. 

POSTER SESSION III 

6:15 PM – 8:15 PM 

Room: Hall 4B 


654 

Directed Evolution of AAV in Pig Airway Epithelia In Vivo 

David D. Dickey, Jamie Bergen, Boulos Nassar, Benjamin 

Steines, Katherine J. D. A. Excoffon, David V. Schaffer, Joseph 

Zabner. 

655 

ERK Inhibition Substantially Improves Early Stage Mortality 

in Acute Pancreatitis: The First Report of AAV Vector- 

Mediated Gene Modulation in an Exocrine Pancreatic 

Disease 

Zuobiao Yuan, Deborah Williard, Erik Twait, Duraisamy 

Kempuraj, Isaac Samuel. 

656 

Transduction of Non-Human Primate Retina with 

Intravitreally Administered AAV Vectors of Different 

Serotypes: Investigations into Inflammation and Possibility 

of Treatment of Contralateral Eye 

Michael J. Lukason, Elizabeth A. Barry, Timothy MacLachlan, 

Samuel C. Wadsworth, Abraham Scaria. 

657 

AAV5 Mediated Exendin-4 Transduction of Salivary Glands 

in Mouse and Rat Obese Models Results in Robust Systemic 

Secretion of Exendin-4 and Improvement of Metabolic 

Parameters 

Giovanni Di Pasquale, Ilaria Dicembrini, Changyu Zheng, 

Drew Michael, Laura Raimondi, Andrea Cozzi, Andrea Loreto, 

Elena Manni, Silvia Berretti, Claudio Pagano, Roberto Vettor, 

Josephine M. Egan, Bruce J. Baum, Carlo Maria Rotella, John 

A. Chiorini, Edoardo Mannucci. 

658 

Enhancing Systemic Delivery of Recombinant Adeno- 

Associated Viruses through Kupffer Cell Depletion 

Matthew L. Hillestad, Adam J. Guenzel, Michael A. Barry. 

659 

Development of an Effective AAV Vector-Based Gene 

Therapy To Treat the PRKAG2-Tg Mice, an Animal Model of 

Autosomal Dominant Progressive Cardiomyopathy 

Kei Adachi, Christopher S. Naitza, Xueyin N. Huang, Ferhaan 

Ahmad, Hiroyuki Nakai. 

660 

Rescuing Adeno-Associated Virus from the Late 

Endosome/Lysosome Long after Infection Improves Apical 

Transduction of Human Airway Epithelia 

Nicholas W. Keiser, Ziying Yan, Diana Lei-Butters, John F. 

Engelhardt. 

661 

New Proteins Providing Host Defense Functions Against 

rAAVs 

Jerome Denard, Cyriaque Beley, Robert Kotin, Philippe 

Moullier, Thomas Voit, Luis Garcia, Fedor Svinartchouk. 

662 

AAV Gene Therapy Augments Chemotherapy in Multi- 

Modal Treatment of Ovarian Carcinoma 

Chelsea M. Bolyard, Matthew D. Stachler, Jeffrey S. Bartlett, 

Douglas M. McCarty. 

663 

Therapeutic Expression of Factor IX in a Murine Hemophilia 

B Model Using a Novel Human Stem Cell Derived AAV 

Serotype 

David M. Markusic, Laura J. Smith, Irene Zolotukhin, Arun 

Srivastava, Saswati Chatterjee, Roland Herzog. 

664 

Single Amino Acid Mutations on the External Surface 

of AAV2 Improve Transduction of Liver and Retina and 

Reduce Neutralization 

Abraham Scaria, Gary White, Michael Lukason, Elizabeth 

DuFresne, Jennifer Sullivan, Samuel Wadsworth. 



POSTER SESSION III — continued 

6:15 PM – 8:15 PM 

Room: Hall 4B 


665 

Variables Affecting AAV8-Mediated Liver Transduction 

Efficiency in Rats 

Gabriella Cotugno, Patrizia Annunziata, Marianthi Karali, 

Sandro Banfi, Alberto Auricchio. 

666 

Micropatterning AAV and Extracellular Matrix Proteins for 

Tissue Engineering 

Kellie I. McConnell, John H. Slater, Jennifer L. West, Junghae 

Suh. 

667 

Gene Transfer to the Murine Cornea In Vivo 

Daniel C. Chung. 

668 

Neutralizing Factors Against Cardiotropic AAVs in Sera 

from Different Animal Models 

Kleopatra Rapti, Vedell Louis-Jeune, Erik Kohlbrenner, 

Kiyotake Ishikawa, Dennis Ladage, Roger J. Hajjar, Thomas 

Weber. 

669 

rAAV8 Mediated Negative Vaccine Therapy in NOD Mouse 

Model 

Yuanqing Lu, Linda Theisen, Christian Grimstein, Matthew 

Parker, Clive Wasserfall, Mark Atkinson, Sihong Song. 

670 

Effects of the MRI Contrast Agent Gadoteridol on the 

Integrity and Distribution of rAAV2 and rAAV5 in the Rat 

Striatum 

Susan M. Osting, Shelby T. Power, James J. Raschke, 

Antoinette D. Bennett, Mavis Agbandje-McKenna, Marina E. 

Emborg, Corinna Burger. 

671 

Cost-Effective and Facile Method of rAAV Production in 

Suspension-adapted HEK 293 Cells 

Huiren Zhao, Thomas Wolfe, Marissa van der Valk, Plewa A. 

Cherylene, Jackie Sheng, Ki Jeong Lee. 

672 

P53-Dependent NF-κB Activity Influenced the Anti-Tumor 

Effect of AAV-Mediated BATF2 Overexpression in Lung 


Zhao Lu, Jing Niu, Wei Wu, Dexi Chen, Wei Ding. 


673 

Single Oral Vaccination with Human Adenovirus 40 Vector 

Elicits Systemic Immune Responses 

Satoshi Yamasaki, Eric Brown, Julia Davydova, Selwyn M. 

Vickers, Masato Yamamoto. 

674 

Novel Adenovirus Vector Generating System Enabling 

Adenoviral Library with 10^10 Diversity 

Yoshiaki Miura, Eric Brown, Julia Davydova, Kazunori Aoki, 

Masato Yamamoto. 

675 

Oncolytic Adenoviral-Mediated Inhibition of Established 

Bone Metastases: A Safe and Effective Systemic 

Therapeutic Approach for Breast Cancer 

Zebin Hu, Helen Gerseny, Zhenwei Zhang, Stuart Stock, Prem 

Seth. 

676 

The dNTP Binding Efficiency of Adenovirus DNA 

Polymerase Contributes to Virus Replication Efficiency and 

Host Cell Tropism 

Cristina Capella-Gonzalez, Michael J. Beltejar, Baek Kim, 

Stephen Dewhurst. 

677 

In Vitro & Vivo Gene Targeting with Adenoviral Vector 

Conjugated Magnetic Nanobeads for Cardiac Regeneration 

Yue Zhang, Wenzhong Li, Gustav Steinhoff, Nan Ma. 

678 

Oncolytic Viruses: A Novel Therapy Against Triple-Negative 

Breast Cancer 

Sepideh Gholami, Chun-Hao Chen, Joshua S. Carson, Dana 

Haddad, Song Taejin, Joyce Au, Jun Kwong, Yuman Fong. 

679 

Generation of Complex High-Capacity Adenoviral Vectors 

with Modified Capsids for Applications In Vitro and In Vivo 

Martin Hausl, Richard Voigtlander, Zsolt Ruzsics, Anja 

Ehrhardt. 

680 

Dual-Expression Adenoviral Vectors in Vaccine 

Development 

Xiangyang Zhou, Juliana C. Small, Dongming Zhou, Raj K. 

Kurupati, Heng Chen, Ang Bian, Hildegund C. Ertl. 

681 

Ad-TβRIIΔcyt Treatment Decreases Liver Steatosis 

and Fibrosis by Decreasing mRNA Expression of CB1 

Cannabinoid Receptor and TGF-β and Increasing MMP-1 

Mayra G. Mena, Ana S. Sandoval, Jazmin Santillan, Juan 

Armendariz. 


Saturday, May 21


136 



6:15 PM – 8:15 PM 

Room: Hall 4B 


682 

Development of a Virus-Associated RNA-Deleted 

Adenovirus Vector 

Mitsuhiro Machitani, Kazufumi Katayama, Fuminori Sakurai, 

Hayato Matsui, Tomoko Yamaguchi, Takayuki Suzuki, Kenji 

Kawabata, Hiroyuki Mizuguchi. 

683 

Pre-Clinical Characterization of Endothelial Cells as Carriers 

of Oncolytic Adenoviruses 

Bart Thaci, Ilya V. Ulasov, Maciej S. Lesniak. 

684 

miR122 Targets Insertion in Wild-Type Serotype 5 

Adenovirus To Ablate Liver Replication 

Sergio Lavilla-Alonso, Erkko Ylösmäki, Kalle Saksela. 

685 

TRAIL-Expressing Oncolytic Viral DNA/Liposome Hybrid 

Vector for Lung Cancer Gene Therapy 

Oh-Joon Kwon, Eunah Kang, Jaerim Kim, Kyungmin Nam, 

Sung Wan Kim, Chae-Ok Yun. 

DNA Vectorology & Gene Targeting - II 

686 

Zinc Finger Nuclease Generation for Fanconi Anemia 

Mark J. Osborn, Morgan L. Maeder, J. Keith Joung, Bruce R. 

Blazar, Jakub Tolar. 

687 

Gene Repair in a Murine Model of SCID-X1 

Gabrielle M. Curinga, Michelle Brault, Jordan Jarjour, Jit Kim, 

Byoung Ryu, Andrew M. Scharenberg, David J. Rawlings. 

688 

Novel Dual AAV Vectors To Express an nNOS-Recruiting 

Mini-Dystrophin Gene for Duchenne Muscular Dystrophy 

Gene Therapy 

Yadong Zhang, Dongsheng Duan. 

689 

Helper-Dependent Adenovirus with Doxycyclin-Inducible 

Expression of Zinc-Finger Nucleases for Targeted 

Transgene Integration in Hematopoietic Stem Cells 

Xiaoying Yao, Hongjie Wang, Ruan van Rensburg, Michael 

Holmes, Philip Gregory, Andre Lieber. 

690 

Optimisation of the 2A Co-Expression System for Gene 

Therapies 

Ekaterina Minskaia, Garry Luke, Martin D. Ryan. 

691 

A Modular Self-Assembling Peptide Scaffold for Tissue 

Engineering and Targeted Gene Delivery 

Joshua Z. Gasiorowski, Joel H. Collier. 

692 

Analysis of 2A-Mediated ‘Cleavage’ 

Valerie Odon, Garry Luke, Martin D. Ryan. 

693 

A Molecular Tool for Gene Integration and Generation of 

Isogenic Mammalian Cell Lines 

Samantha A. Stuckey, Francesca Storici. 

694 

Customized Antibiotic Free Non-Viral Plasmid Vectors for 

Therapy and Vaccination 

Jeremy M. Luke, Justin M. Vincent, Clague P. Hodgson, James 

A. Williams. 

695 

pFARs, Plasmids Free of Antibiotic Resistance Markers, 

Display High-Level Transgene Expression in Muscle, Skin 

and Tumour Cells 

Corinne Marie, Gaëlle Vandermeulen, Mickaël Quiviger, 

Magali Richard, Véronique Préat, Daniel Scherman. 

696 

The p5 Promoter Sequence of AAV Genome Regulates the 

Direction of Transgene Insertion into the AAVS1 Site 

Masashi Urabe, Satsuki Miyata, Akira Onishi, Tomonori 

Tsukahara, Hiroaki Mizukami, Akihiro Kume, Keiya Ozawa. 

697 

Improvement of Gene Targeting at the Human rDNA Locus 

by Zinc Finger Nucleases 

Youjin Hu, Di Xiao, Xionghao Liu, Lingqian Wu, Desheng 

Liang. 

698 

Nonviral-Mediated Endostatin Delivery Results in 

Inhibition of Fibrosarcoma Growth 

Jianxiong Peng, Lingqian Wu, Xionghao Liu, Desheng Liang. 

699 (MOVED TO POSTER SESSION II AFTER ABSTRACT 438) 

The Role and Fate of Excess Polycations in Chitosan-Based 


Marc Thibault, Melina Astolfi, Marc Lavertu, Vincent Darras, 

Michael D. Buschmann. 

700 

Rep of AAV Inhibits HSV Amplification by Degradation 

PML-NBs Proteins That Necessary for ICP0 Mediated Viral 

Processes 

Jinzhong Chen, Ran Wang, Jinjin Wang, Limin Wan, Jing-lun 

Xue. 




6:15 PM – 8:15 PM 

Room: Hall 4B 

Physical Methods of Delivery II 

701 

Piezoelectric Permeabilization of Mammalian Dermal 

Tissue for In Vivo DNA Delivery Leads to Enhanced Protein 

Expression and Increased Immunogenicity 

Kate E. Broderick, Thomas Kardos, Jay R. McCoy, Michael P. 

Fons, Stephen Kemmerrer, Niranjan Y. Sardesai. 

702 

Combination Chemo-Antiangiogenic Therapy for 

Metastatic Colorectal Carcinoma 

Lalitha Belur, Kelly M. Podetz-Petersen, Brent Sorenson, 

Daniel Saltzman, S. Ramakrishnan, R. Scott McIvor. 

703 

Nanosecond Electric Pulses Modulate the Expression of 

Electrotransferred Genes 

Aude Silve, Marie Gilbert, Vanessa Joubert, Julien Villemejane, 

Lluis M. Mir. 

704 

The Amaxa Nucleofector System and Standard 

Electroporation: A Comparison of the Efficiency of DNA 

Nuclear Localization 

Marta H. Ekstrom, David A. Dean. 

705 

Development of Electromotor-Driven Injector for 

Hydrodynamic Gene Delivery 

Takeshi Yokoo, Kenya Kamimura, Takeshi Suda, Masafumi 

Oda, Guisheng Zhang, Dexi Liu, Yutaka Aoyagi. 

706 

Protein Transfer into Human Cells by VSV-G Induced 

Nanovesicles 

Philippe E. Mangeot, Sandra Dollet, Mathilde Girard, Claire 

Ciancia, Marc Peschanski, Vincent Lotteau. 

707 

A Proteoliposome Containing Apolipoproteins A-I Mutant 

(V156K) Enhances Rapid Tumor Regression Activity of 

Human Origin Oncolytic Adenovirus in Carcinogen Induced 

Tumor-Bearing Zebrafish 

Jung-Heun Park, Seori Jin, Kyung-Hyun Cho. 

708 

Delivery of VEGF165 To Enhance Healing of Ischemic Skin 

Flaps in Rats Using a Multi Electrode Array (MEA) 

Gaurav Basu, Harre Downey, Siqi Guo, Richard Heller. 

709 

Synthesis and Evaluation of Stearylated Hyaluronic Acid 

Material for Active Liposomal Delivery to Liver Endothelial 


Naoyuki Toriyabe, Yasuhiro Hayashi, Mamoru Hyodo, 

Hideyoshi Harashima. 

710 

Sonoporation of Plasmid DNA Driven by Glucagon 

Promoter to Pancreatic Islet a-Cell for Diabetes Gene 


Jeong H. Park, Minhyung Lee, Hye S. Jung, Chang S. Yoon, Tae 

K. Kim, Min J. Kwon, Soon H. Lee, Kyung S. Ko, Byung D. Rhee, 

Mi K. Kim. 

711 

Non-Invasive Electro-Gene Delivery to the Skin Using a 

Multiple Electrode Array 

Siqi Guo, Amy Donate, Gaurav Basu, Kathryn Lundberg, Loree 

Heller, Richard Heller. 


Gene & Cell Therapy III 

712 MOVED TO POSTER SESSION I 

Hematopoietic Stem Cell Gene Therapy with a Lentiviral 

Vector for the Multi-Systemic Lysosomal Storage Disorder 

Cystinosis 

Frank Harrison, Brian A. Yeagy, Donald B. Kohn, Daniel R. 

Salomon, Stephanie Cherqui. 

713 

Towards Lentiviral Gene Therapy for the Treatment of 

Pompe Disease 

Merel M. Stok, Helen H. de Boer, Trudi T. P. Visser, Arnold J. J. 

Reuser, Elza E. D. van Deel, Dirk-Jan D. J. Duncker, Niek N. P. 

van Til, Gerard G. Wagemaker. 

714 

Chimerism of Bone Marrow Reduces the Glycolipid Storage 

in Fabry Disease Mice 

Takayuki Yokoi, Hiroshi Kobayashi, Yoshikatsu Eto, Nobuyuki 

Ishige, Teruyuki Kitagawa, Makato Otsu, Hiromitsu Nakauchi, 

Hiroyuki Ida, Toya Ohashi. 

715 

Lentiviral Transduction of MPS1 Bone Marrow Cells Results 

in High Production of alpha-L-Iduronidase In Vivo 

Henk Rozemuller, Petra Moerer, Niek P. van Til, JaapJan 

Boelens, Tom J. de Koning, Anton C. Martens, Gerard 

Wagemaker, Nico M. Wulffraat. 


Saturday, May 21


138 



6:15 PM – 8:15 PM 

Room: Hall 4B 


Gene & Cell Therapy III 

716 

Optimisation of Lentiviral Transduction Conditions 

of Haematopoietic Stem Cells for Treatment of 

Mucopolysaccharidosis Type IIIA (MPSIIIA) 

Ana Sergijenko, Alex Langford-Smith, Kia Langford-Smith, 

Rob Wynn, J. Ed Wraith, Simon Jones, Fiona Wilkinson, Brian 

Bigger. 

717 

Disease Improvement with Neonatal Intracranial AAV and 

Systemic Lentiviral Gene Therapy in Sanfilippo Syndrome 

Type B Mice 

Coy D. Heldermon, Elizabeth Qin, Kevin K. Ohlemiller, Erik D. 

Herzog, Carole Vogler, Mark S. Sands. 

718 

Aortic Dilatation in Mucopolysaccharisosis VII Mice 

Cannot Be Ameliorated by Deficiency of Cathepsin S or 

Matrix Metalloproteinase Activity, but Can Be Markedly 

Amelioraged by Marked Reductions in Expression of an 

As-yet-Unknown Gene That Prevents Upregulation of 

Inflamatory Pathways 

Guillerme Baldo, Ruth Howe, Susan Wu, Russell Knuteen, 

Meera Ramamoothy, Robert Q. Meecham, Katherine Ponder. 

719 

Upregulation of Inflammatory Pathways and Proteases 

May Lead to Aortic Valve Insufficiency in MPS VII Dogs and 

Can Be Prevented with Neonatal Retroviral Gene Therapy 

Guilherme Baldo, Paul Bigg, Susan Wu, Yuli Liu, Mark Haskins, 

Henri Bai, Meg Sleeper, Katherine P. Ponder. 

720 

Intra-Cerebroventricular or Intravenous Injection of 

AAVrh10 Serotype Expressing Mouse GALC Results in 

Increased Life-Span and Widespread GALC Activity in CNS 

of a Mouse Model of Globoid Cell Leukodystrophy 

Mohammad A. Rafi, Han Zhi Rao, Paola Luzi, David A. Wenger. 

721 

Lentiviral Mediated Neonatal Gene Therapy for Krabbe 

Disease Model Mouse 

Hiroshi Kobayashi, Masamichi Ariga, Yohta Shimada, Sayoko 

Izuka, Takayuki Yokoi, Takahiro Fukuda, Takeo Iwamoto, 

Yoshikatsu Eto, Hiroyuki Ida, Toya Ohashi. 

722 

Efficacy of a Combined Intracerebral and Systemic Gene 

Delivery Approach for the Treatment of a Severe Lysosomal 

Storage Disorder 

Carmine Spampanato, Elvira De Leonibus, Paola Dama, 

Annagiusi Gargiulo, Alessandro Fraldi, Cristina N. Sorrentino, 

Alberto Auricchio, Andrea Ballabio, Enrico M. Surace. 

723 

Intrathecal Administration of Type 9 AAV Vector Expressing 

Arylsulfatase A Is Effective for Reduction of Sulfatide 

Storage but Not for Correction of Neurological Deficits in 

Adult Metachromatic Leukodystrophy Model Mice with 

Overt Neurological Symptoms 

Noriko Miyake, Koichi Miyake, Atsushi Sakai, Motoko 

Yamamoto, Ayumi Endo, Hidenori Suzuki, Takashi Shimada. 

724 

Alternative Splicing of the Human Iduronate 2-Sulfatase 

Gene and Implications in Gene Therapy 

Ni-Chung Lee, Wuh-Liang Hwu, Lung-Ji Chang, Yin-Hsiu Chien. 



725 

Preliminary Results of Molecular Cardiac Surgery Mediated 

Transfer of scAAV6-βARKct in a Reproducible Model of 

Ischemic Cardiomyopathy 

Anthony S. Fargnoli, Michael G. Katz, Elena Marusich, Jason 

Abramowitz, James J. Pilla, Joseph Rabinowitz, Walter J. Koch, 

Charles R. Bridges. 

726 

Retroviral Vector Gene Therapy Delays Mitral Valve 

Regurgitation in Mucopolysaccharidosis VII Dogs But 

Does Not Prevent Disease Long Term Due to Failure to 

Completely Prevent Induction of Inflammaory Pathways 

Paul W. Bigg, Guillerme Baldo, Meg Sleeper, Susan Wu, Yuli 

Liu, Henry Bai, Patricia O’Donnell, Venkata Rokkam, Mark E. 

Haskins, Katherine P. Ponder. 

727 

MicroRNAs 99b, 181a and 181b Potentiate Pluripotent hES 

Cell Endothelial Differentiation and Comprise Part of an 

Endothelial Cell-MicroRNA Signature Panel 

Nicole M. Kane, Lynsey Howard, Raya Khanin, John McClure, 

Christopher R. Breen, Graeme Milligan, Andrew H. Baker. 

728 

In Vivo Functional Selection Using an AAV Library Encoding 

the Mouse Secretome Identifies Ghrelin as a Powerful 

Cardioprotective Molecule 

Giulia Ruozi, Serena Zacchigna, Antero Macedo, Matteo 

Dalferro, Antonella Falcione, Lorena Zentilin, Mauro Giacca.



6:15 PM – 8:15 PM 

Room: Hall 4B 


729 

Investigation of miRNA Targeting Sequences for Selective 

Regulated Gene Therapy in Cardiomyocytes 

Carolyn Haggerty, Caroline Fattah, Stuart A. Nicklin. 

730 

Myocardial Infarction-Induced Acute Inflammation Impairs 

Therapeutic Efficacy of Bone Marrow Cells 

Xiaoyin Wang, Viola C. Lam, Daniel J. Haddad, Yan Zhang, 

Brian C. Clifford, Kranthi Pinnamaneni, Maya J. Bartel, Richard 

E. Sievers, Larry Carbone, Scott Kogan, Yerem Yeghiazarians, 

Michelle Hermiston, Matthew L. Springer. 

731 

AAV8-Mediated Long Term Expression of Human LCAT 

Significantly Improves Lipid Profiles in hCETP; Ldlr +/- Mice 

Heather H. Zhou, Zhu Chen, Donald Chu, Jose Castro-Perez, 

Weihua Ni, Aiwu Zhang, Mihajlo L. Krsmanovic, Dan Xie, Vinit 

Shah, Steven J. Stout, David G. McLaren, Alice C. Stefanni, Sang 

Ho Lee, Andrew S. Plump, Brian K. Hubbard, Thomas F. Vogt. 

732 

Use of a Helper-Dependent Adenoviral Vector and a 

Rabbit Model To Test Atheroprotective Gene Therapy with 

Interleukin-10 

Liang Du, Nagadhara Dronadula, Shinji Tanaka, David A. Dichek. 

733 

Uniform Field-Controlled Magnetic Targeting Enables 

Efficient Site-Specific Delivery of Endothelial Progenitor 

Cells to Stented Arteries in the Rat Carotid Model of 

Restenosis 

Michael Chorny, Ilia Fishbein, Richard Adamo, Robert J. Levy. 

734 

Enhancing MSC-Based VEGF Gene Therapy in Rat 

Myocardial Infarction Model Using Facial Amphipathic Bile 

Acid-Conjugated Polyethyleneimine 

Sun Hwa Kim, Hyeong-Ho Moom, Minhyung Lee, Ji Hoon 

Jeong, Donghoon Choi. 

735 

Genetically Modified Stem Cells for the Treatment of 

Myocardial Infarction Using Novel Lysine-Based Nonviral 

Carrier System 

Mohamed I. Nounou, Cori Wijaya, Dongling Li, Sameer 

Saifuddin, Yi Zheng, Guilherme Silva, Bradley McConnell, 

Malavosklish Bikram. 

736 

DNA Vaccine for High Blood Pressure – Anti-Angiotensin II 

Therapy in Spontaneously Hypertensive Rats 

Hiroshi Koriyama, Hironori Nakagami, Futoshi Nakagami, 

Yasufumi Kaneda, Ryuichi Morishita. 

737 

Hyperhomocysteinemia-Induced Endothelial Dysfunction 

Does Not Accelerate Progression of Atherosclerosis in 

Hypercholesterolemic Mice 

Frank Jacobs, Eline Van Craeyveld, Stephanie C. Gordts, 

Ilayaraja Muthuramu, Jan Emmerechts, Marc Hoylaerts, Paul 

Herijgers, Bart De Geest. 

738 

Effects of Tetrahydrobiopterin and Arginine on Nitric Oxide 

Synthesis and ROS Production in Ad-iNOS Transduced Rat 

Aortic Smooth Muscle and Endothelial Cells 

Scott P. Forbes, Richard F. Adamo, Ricardo Corrales, Michael 

Chorny, Robert J. Levy, Ilia Fishbein. 

739 

Helper-Dependent Adenovirus Is a Promising Vector for 

Atheroprotective Gene Therapy 

Bo Jiang, Liang Du, Kun Qian, David A. Dichek. 

740 

Anti-Apoptotic Effects of Antibody-Protein A-HSP27 Fusion 

Proteins in a Rat Myocardial Infarction Model 

Nahyun Kim, Jung Ah Shin, Min-Ji Cha, Andrew Jackson, Ki- 

Chul Hwang, Priti Kumar, Sang-Kyung Lee. 

741 

Engineered Monocytes To Treat Ectopic Calcification 

Meiting Wu, Hsueh-Ying L. Yang, Cameron Rementer, 

Anthony Blau, Cecilia M. Giachelli. 

742 

HGF Plasmid Electroporation for Acute Myocardial 

Infarction Treatment 

Leonardo Pinto Carvalho, Eduardo G. Yasumura, Vivian 

Samoto, Priscila M. A. Denapoli, Vera Saleme, Raquel Sirvente, 

Christina M. Takiya, Sang W. Han. 

743 

RNA Inhibitors of Intimal Hyperlasia 

William H. Thiel, Bojana Stanic, Jennifer Streeter, Xiuying Liu, 

Francis J. Miller, Jr., Paloma H. Giangrande. 


Saturday, May 21


140 



6:15 PM – 8:15 PM 

Room: Hall 4B 

Neurologic & Ophthalmic 


744 

Human MiniPromoters To Drive Selected Expression in the 

Brain, Spinal Cord, and Eye; an Expanded Collection 

Kathleen G. Banks, Stéphanie Laprise, Andrea McLeod, Douglas 

J. Swanson, Li Liu, Elodie Portales-Casamar, Magdalena 

I. Swanson, Steven J. M. Jones, Robert A. Holt, Wyeth W. 

Wasserman, Daniel Goldowitz, Elizabeth M. Simpson. 

745 

Comparison of AAV-Mediated Transduction of Different 

Brain Structures on Enzyme Distribution and Lysosomal 

Storage Correction in the CNS of GM1-Gangliosidosis Mice 

Cara M. Weismann, Miguel Sena-Esteves. 

746 

Transport of AAV Vectors within the Brain Is Serotype 

Dependent 

Adrian P. Kells, Ernesto Aguilar Salegio, John Forsayeth, 

Krystof S. Bankiewicz. 

747 

Biochemical and Histological Improvements Correlate with 

Post-Rescue Functional Gains after Combined AAV5 Gene 

Therapy and Copper in a Mouse Model of Menkes Disease 

Anthony Donsante, Patricia M. Verfas, Elisabeth J. Rushing, 

Stephen G. Kaler. 

748 

Compacted DNA Nanoparticles Efficiently Transfect Retinal 

Pigment Epithelial Cells and Provide Long-Term Expression 

Adarsha Koirala, Rasha S. Makkia, Mark J. Cooper, Muna I. 

Naash. 

749 

Peripheral Delta Opioid Receptor-Mediated Analgesia and 

Neuropathic Pain: Modulation of Receptor Expression in 

Primary Afferents Using Herpes Simplex Virus 

Husam K. Mohammad, Srinivasa Raja, Steven P. Wilson, Sarah 

M. Sweitzer. 

750 

The Equine Infectious Anaemia Virus-Based Lentiviral 

Vector Is an Effective Platform for Gene Therapy for Ocular 

Diseases 

James Miskin, Peter Widdowson, Katie Binley, Scott Ellis, 

Jackie de Belin, Julie Loader, Georgina Ferrige, Diana 

Angell-Manning, Marie Carlucci, Michelle Kelleher, Kyriacos 

Mitrophanous, Stuart Naylor. 

751 

Corneal Gene Delivery: Chitosan Oligomer as a Carrier of 

CpG Rich, CpG Free, or S/MAR Plasmid DNA 

Eytan A. Klausner, Zhong Zhang, Suet P. Wong, Robert L. 

Chapman, Michael V. Volin, Richard P. Harbottle. 

752 

rAAV-Mediated shRNA Knock-Down of Alpha-Synuclein 

in the Rat Substantia Nigra Results in Aberrant Dopamine 

Handling 

Ronald J. Mandel, Aaron C. Rising, Tahsin Khundkar, Fredric P. 

Manfredsson. 

753 

Neuroprotective Gene Expression with AAV8 for Oxygen- 

Glycose Deprivation in Organotypic Hippocampal Culture: 

A Model of Ischemic Stroke 

Juliana Adão-Novaes, Rafael Linden, Hilda Petrs-Silva. 

754 

Direct Comparison of Administration Routes for AAV 8 

Mediated Ocular Gene Therapy 

Tsutomu Igarashi, Koichi Miyake, Nagisa Asakawa, Takashi 

Shimada, Hiroshi Takahashi. 

755 

Interplay between SNCY and LRRK2: Development of a 

Double Transgenic Mouse Model for PD 

Xiaomin Su, Hong Cao, Howard J. Federoff. 

756 

Chemotherapeutic Drugs Enhance rAAV2 Transduction 

Efficiency and Improve rAAV2-CNTF Induced 

Photoreceptor Survival Both In Vitro and In Vivo 

Qian Huang. 



757 

Systemic Reversal of Dominant Muscle Disease in a Mouse 

Model of Muscular Dystrophy 

Sergia Bortolanza, Davide Gabellini, Joel R. Chamberlain. 

758 

Blocking the NF-κB Pathway Enhances Mini-Dystrophin 

Efficiency in Dystrophin/Utrophin Deficient Mice 

Qing Yang, Ying Tang, Anmin Chen, Fengjin Guo, Freddie H. 

Fu, Johnny Huard, Bing Wang. 

759 

Human Involucrin Promoter Resists Spreading Methylation 

and Supports Compartment Specific Gene Expression in 

Engineered Skin Grafts 

Wei Li Di, Ekaterina Semenova, Fernando Larcher, John 

Harper, Adrian Thrasher, Waseem Qasim.



6:15 PM – 8:15 PM 

Room: Hall 4B 


760 

AAV2 Mediated VEGF Gene Transfer Leads to Increased 

Bone Formation and Remodeling of Bone Allografts 

Mette J. Koefoed, Alexandra G. Pedersen, Kjeld Soballe, 

Thomas G. Jensen, Michael Ulrich-Vinther. 

761 

Gene-and-Stem Cell Therapy for Vertebral Bone Fracture 

Dmitriy Sheyn, Ilan Kallai, Wafa Tawackoli, Yoram Zilberman, 

Amir Lavi, Susan Su, Anthony Oh, Xiaoyu Da, Zulma Gazit, 

Gadi Pelled, Dan Gazit. 

762 

Inactivation of Dystrophin Expression Via Cre-loxP 

Mediated Gene Excision 

Julian N. Ramos, Andrea Arnett, Brian Schultz, Jeffrey S. 

Chamberlain. 

763 

A Miniature Muscle Model Suitable for the Rapid Screening 

of Virally Delivered Transgenes 

Rainer Ng, Jeffrey S. Chamberlain. 

764 

Immune Tolerance Induction in Canine X-Linked Muscular 

Dystrophy with rAAV9-Microdystrophin Transduction 

Hiromi Hayashita-Kinoh, Naoko Yugeta, Hironori Okada, Yuko 

Nitahara-Kasahara, Tomoko Chiyo, Takashi Okada, Shin’ichi 

Takeda. 

765 

Interference of Myostatin and TGF-beta Signaling by 

Antisense-Mediated Exon Skipping in ALK4/5 Receptors 

Dwi U. Kemaladewi, Sandra H. van Heiningen, Annemieke 

Aartsma-Rus, Gert-Jan B. van Ommen, Peter ten Dijke, Peter 

A. C. ‘t Hoen, Willem M. H. Hoogaars. 

766 

AAV9-Mediated FKRP Gene Therapy Restores the 

Expression of Functional Glycosylation of α-DG 

Lei Xu, Pei Lu, Chi-Hsien Wang, Jianbin Li, Elizabeth Keramaris, 

Xiao Xiao, Qi Long Lu. 

767 

Repair of Large Bone Defects Using Gene Activated Muscle 

Tissue Grafts 

Oliver B. Betz, Volker M. Betz, Peter Augat, Volkmar Jansson, 

Peter E. Mueller. 

768 

Defining Outcome Measures in Sporadic IBM for a 

Follistatin Gene Transfer Clinical Trial 

Linda P. Lowes, Lindsay N. Alfano, Laurence Viollet, Xiomara 

Q. Rosales, Brian Kasper, K. Reed Clark, Zarife Sahenk, Kevin 

M. Flanigan, Jerry R. Mendell. 

769 

AAV-Based shRNA Silencing of NF-κB Ameliorates Muscle 

Pathologies in mdx Mice 

Qing Yang, Ying Tang, Kara Imbrogno, Aiping Lu, Anmin Chen, 

Fengjin Guo, Freddie H. Fu, Johnny Huard, Bing Wang. 

770 

Muscle Fiber Type-Predominant Promoter Activity in 

Lentiviral-Mediated Transgenic Mouse 

Tomohiro Suga, En Kimura, Yuka Morioka, Masahito Ikawa, 

Sheng Li, Katsuhisa Uchino, Yuji Uchida, Satoshi Yamashita, 

Yasushi Maeda, Jeffrey S. Chamberlain, Makoto Uchino. 

771 

Noninvasive Monitoring of Whole Body Muscle Function in 

Dystrophin-Deficient Dogs 

Jin-Hong Shin, Brian B. Greer, Chady H. Hakim, Zhihai He, 

Dongsheng Duan. 


773 

Comparison of Efficacy of a Novel Double-Strand AAV2 

Vector Harboring VEGF cDNA to AAV-SS-VEGF: In Vitro 

Transgene Expression and In Vivo Application To Enhance 

Survival of Ischemic Flaps 

Xiao Tian Wang, Bella Avanessian, Qiangzhong Ma, Yuqing 

Tang, Heather Durfee, Paul Y. Liu. 

774 

Serum Neural Cell Adhesion Molecule (NCAM) Is 

Hyposialylated in Hereditary Inclusion Body Myopathy 

(HIBM) 

Yadira Valles-Ayoub, Saghi Esfandiarifard, Zeshan Khokher, 

Pedram Sinai, Rosangela Carbajo, Daniel No, Babak Darvish, 

Marvin Pietruszka, Emil Kakkis, Daniel Darvish. 

Cancer - Immunotherapy III 

775 

Adoptive T Cell Therapy Generates Tumor Escape Variants 

through Induction of Genomic Instability 

Karen Kaluza, Jill Thompson, Heather Flynn Gilmer, Darlene 

Knutson, Richard Vile. 

776 

Gene Therapy with a Novel Fusion Protein of Interferon 

Alpha and Apolipoprotein A-I Exerts Antitumor Effects 

Jessica Fioravanti, Jose I. Quetglas, José Medina-Echeverz, 

Nuria Ardaiz, Jesús Prieto, Cristian Smerdou, Pedro 

Berraondo. 


Saturday, May 21


142 



6:15 PM – 8:15 PM 

Room: Hall 4B 


777 

Highly Efficient and Safe Vectors for TCR Gene Therapy: 

Silencing of Endogenous TCR Improved Expression and 

Anti-Tumor Reactivity of Transduced Tumor-Specific TCRs 

in Human Lymphocytes 

Sachiko Okamoto, Hiroaki Ikeda, Hiroshi Fujiwara, Ikuei 

Nukaya, Hirofumi Yoshioka, Masaki Yasukawa, Hiroshi Shiku, 

Junichi Mineno. 

778 

Development of a Drug Resistant Immunocompetent Cell- 

Based Therapy To Treat Neuroblastoma and Other Cancers 

Anindya Dasgupta, Jordan E. Shields, Robert Moot, H. Trent 

Spencer. 

779 

Gold Nanoshell Induced Photothermal Therapy Ablates 

Primary Tumors and Enhances Anti-Tumor Activity of 

Antigen-Specific Cytotoxic T Lymphocytes 

Adham S. Bear, Laura C. Kennedy, Joseph K. Young, Rebekah 

A. Drezek, Aaron E. Foster. 

780 

Tumor Immune Evasion Enforced by Viral cDNA Library 

Vaccination Can be Exploited for Ambush of Emerging 

Tumor Cell Variants 

Phonphimon Wongthida, Elizabeth Ilett, Jose Pulido, Timothy 

Kottke, Jill Thompson, Feorillo Galivo, Peter Selby, Alan 

Melcher, Richard Vile. 

781 

Adoptive Immunotherapy Using EphA2-Specific T Cells for 

the Treatment of Glioblastoma Multiforme 

Kevin K. H. Chow, Vita S. Salsman, Sunitha Kakarla, Claudia 

Gerken, Yvonne Kew, Robert G. Grossman, Suzanne Z. Powell, 

Nabil Ahmed, Stephen M. Gottschalk. 

782 

Improved T Cell Survival, Tumor Localization and Tumor 

Eradication by Folate Receptor-α Redirected T Cells Is 

Achieved by Provision of CD137 Costimulatory Signaling 

Degang Song, Silvana Canevari, Carl H. June, George Coukos, 

Daniel J. Powell, Jr. 

783 

BPX-101 Vaccine: Regulation of CD40 Signaling in DCs In 

Vivo Leads to Spiking Cytokines Correlative with Objective 

Responses in mCRPC Patients in a Phase I/IIa Trial 

David M. Spencer, Natalia Lapteva, Jan O. Kemnade, Jon M. 

Levitt, John McMannis, Guru Sonpavde, Kevin M. Slawin. 

784 

Pre-Clinical Safety and Toxicity Dose-Finding of a Novel Bi- 

Cistronic High-Capacity Adenoviral Vector Encoding Flt3L 

and TK: Identification of a Maximally Tolerated Dose in the 

Brain with Restricted Biodistribution of Vector Genomes 

Mariana Puntel, A. K. M. G. Muhammad, Weidong Xiong, 

Kyle Kelson, Alireza Salem, Kurt M. Kroeger, Chunyan Liu, 

Catherine Farrokhi, Liliana Lacayo, Robert N. Pechnick, Donna 

Palmer, Philip Ng, Maria G. Castro, Pedro R. Lowenstein. 

785 

Targeting of Myeloid Leukemia Stem Cells through Genetic 

Redirection of T Cells Against CD44 Variant 6 

Monica Casucci, Laura Falcone, Barbara Camisa, Zulma 

Magnani, Claudio Bordignon, Barbara Savoldo, Gianpietro 

Dotti, Chiara Bonini, Attilio Bondanza. 

786 

Generation of Antigen Specific T Cells by Transplant of 

Human Hematopoietic Stem/Progenitor Cells (HSPC) 

Transduced with a Lentiviral Vector Carrying the Genes for 

a T Cell Receptor Specific for MART-1 

Francesca Giannoni, Cinnamon L. Hardee, Jennifer P. Wherley, 

Don B. Kohn. 

787 

Anti-Glioma Immune Response Induced by Conditional 

Cytotoxic/Immune-Stimulatory Gene Therapy Requires 

pDC Activation Triggered by Circulating Brain Tumor DNA 

Marianela Candolfi, Kader Yagiz, Karthika Balasubramanian, 

Mariana Puntel, Gwendalyn D. King, Yohei Mineharu, A. K. 

M. G. Muhammad, David Foulad, Nicholas Barnett, Kurt M. 

Kroeger, Pedro R. Lowenstein, Maria G. Castro. 

788 

Myeloid Derived Suppressor Cells Expand and Infiltrate 

Brain Tumors in Response to Circulating Glioma-Derived 

Factors 

Marianela Candolfi, Kader Yagiz, Hikmat Assi, A. K. M. G. 

Muhammad, Chunyan Liu, David Foulad, Gabrielle Alzadeh, 

Daniel A. Pisera, Kurt M. Kroeger, Pedro R. Lowenstein, Maria 

G. Castro. 

789 

Enhancing CD8 T Cell Function by IL-2 Potentiates the 

Efficacy of a Combined Cytotoxic Immunostimulatory Gene 

Therapy in an Aggressive Glioma Model 

Yohei Mineharu, A. K. M. Ghulam Muhammad, Mariana 

Puntel, Marianela Candolfi, Weidong Xiong, Kurt M. Kroeger, 

Chunyan Liu, Niyati Bondale, Pedro R. Lowenstein, Maria G. 

Castro. 




6:15 PM – 8:15 PM 

Room: Hall 4B 


790 

Tumor-Specific Viral Inflammation Facilitates Effective 

Dendritic Cell Cancer Immunotherapy in a Regulatory T 

Cell-Dependent Manner 

Norman Woller, Sarah Knocke, Bettina Mundt, Engin 

Guerlevik, Nina Struever, Michael P. Manns, Tim Sparwasser, 

Stefan Kubicka, Florian Kuehnel. 

791 

Anti-Tumor Activity of Engineered T Lymphocytes 

Expressing an Anti-CD19 CAR for B Cell Lymphoma 

Tomonori Tsukahara, Ken Ohmine, Ryosuke Uchibori, Masashi 

Urabe, Hiroaki Mizukami, Akihiro Kume, Isabelle Riviere, 

Michel Sadelain, Renier Brentjens, Keiya Ozawa. 

792 

Inhibition of Experimental Colon Cancer Liver Metastasis 

by IL-15 Immunogene Therapy 

Xianghui He, Dongbing Zhou, Yifeng Wang, Weidong Li, Liwei 

Zhu. 


793 

Antifibrotic Properties of Transarterial VSV Oncolytic 

Therapy for Hepatocellular Carcinoma in Rats with 

Thioacetamide-Induced Liver Fibrosis 

Jennifer Altomonte, Enrico De Toni, Irene Esposito, Claus 

Hellerbrand, Sabrina Marozin, Oliver Ebert. 

794 

Enhancing Therapeutic Outcome Using Radiation and 

Measles Infected CIK Cell Carriers for the Treatment of 

Disseminated Multiple Myeloma 

Yun-Wen Chen, Chunsheng Liu, Stephen J. Russell, Kah-Whye 

Peng. 

795 

Treatment of Cancer with Oncolytic Adenovirus Combined 

with Temozolomide, an Autophagy Inducer 

Ilkka Liikanen, Laura Ahtiainen, Vincenzo Cerullo, Petri 

Nokisalmi, Sophie Escutenaire, Iulia Diaconu, Sari Pesonen, 

Anniina Koski, Lotta Kangasniemi, Elina Haavisto, Kaarina 

Partanen, Timo Joensuu, Anna Kanerva, Akseli Hemminki. 

796 

Oncolytic Virus Therapy for Bladder Cancer Using a Third- 

Generation HSV-1 Armed with Interleukin 12 

Jiangang Hou, Hiroshi Fukuhara, Yuzuri Tsurumaki, Yukio 

Homma, Yasushi Ino, Tomoki Todo. 

797 

Oncolytic Adenovirus Induces Autophagic Cell Death 

through an E2F1-microRNA-7-Epidermal Growth Factor 

Receptor Axis in Human Cancer Cells 

Hiroshi Tazawa, Shuya Yano, Ryosuke Yoshida, Yuuri 

Hashimoto, Yasuo Urata, Toshiyoshi Fujiwara. 

798 

EGFR-Targeted and Cytosine Deaminase-Armed Measles 

Virus in Combination with 5-Fluorocytosine as a Novel 

Chemovirotherapy for Head and Neck Squamous Cell 

Carcinoma 

Karim Zaoui, Sascha Bossow, Christian Groβardt, Mathias 

F. Leber, Christoph Springfeld, Christof von Kalle, Peter K. 

Plinkert, Guy Ungerechts. 

799 

Generation of Fiber-Modified, Conditionally-Replicating 

Adenovirus Vectors Expressing the Sodium Iodide 

Symporter for Prostate Cancer Therapy 

Michael J. Oneal, Miguel A. Trujillo, Julia Davydova, Masato 

Yamamoto, John C. Morris. 

800 

Biological Effects of Oncolytic Adenovirus on Epithelial- 

Mesenchymal Transition in Human Lung Cancer Cells 

Yuuri Hashimoto, Shuya Yano, Hiroshi Tazawa, Ryosuke 

Yoshida, Yasuo Urata, Shunsuke Kagawa, Toshiyoshi Fujiwara. 

801 

Targeting of Prostate Cancer Cells with the Novel 

Replication-Selective Adenoviral Mutant AdΔΔ in 

Combination with the Phytochemical Drugs Eqoul and 

Resveratrol 

Virginie S. Adam, Daniel Oberg, Nicholas Lemoine, Gunnel 

Halldén. 

802 

Systemically Administered Vesicular Stomatitis Virus 

Induces Neurotoxicity in Myeloma-Bearing Mice 

Danielle N. Yarde, Rebecca A. Nace, Shruthi K. Naik, Mark J. 

Federspiel, Stephen J. Russell. 

803 

The Effect of Combination Therapy of Oncolytic Virus hrR3 

and Bevacizumab in Human Gastric Cancer 

Gewen Tan, Hideki Kasuya, Tevfik T. Sahin, Toshio Shikano, 

Suguru Yamada, Akiyuki Kanzaki, Kazuo Yamamura, Tsutomu 

Fujii, Hiroyuki Sugimoto, Shuji Nomoto, Yoko Nishikawa, Shin 

Takeda, Akimasa Nakao. 

804 

p53-Dependent Expression of the Meganuclease I-Sce I 

Allow Self-Restriction of Oncolytic Adenovirus in Normal 

Tissue 

Peter Schache, Engin Guerlevik, Anneliese Goez, Nina 

Struever, Michael P. Manns, Stefan Kubicka, Florian Kuehnel. 


Saturday, May 21


144 



6:15 PM – 8:15 PM 

Room: Hall 4B 


805 

Promoter-Mediated Replication of Adenoviruses Induces 

Apoptosis-Independent Cell Death in p53-Null Pancreatic 

Carcinoma Cells 

Masatoshi Tagawa, Suguru Yamauchi, Kiyoko Kawamura, 

Shinya Okamoto, Shan Yang, Wen Chang Li, Hiroshi 

Kobayashi, Shuji Kubo, Yuji Tada, Yuichi Takiguchi, Koichiro 

Tatsumi, Kenzo Hiroshima, Hideaki Shimada. 

806 

Active Targeting of Bioreducible Polymer Concealing 

Oncolytic Adenovirus to Cancer Cells Expressing Integrins 

Jaesung Kim, Hye Yeong Nam, Tae-Il Kim, Pyung-Hwan Kim, 

Chae-Ok Yun, Sung Wan Kim. 

807 

A Replication-Selective Adenovirus Expressing the 

Prodrug-Converting Enzyme CD/UPRT Efficiently Inhibits 

Tumour Growth in Prostate Cancer Models 

Maria Ekblad, Daniel Oberg, Nicholas Lemoine, Gunnel 

Halldén. 

808 

Oncolytic Adenoviral Vector Targeted to Hepatocellular 

Carcinoma Expressing Low Levels of miR-122 

David Sharon, Michael Shumann, Sandeep Randhawa, Mary 

Hitt. 

Cancer-Targeted Gene & Cell Therapy III 

809 

E10A, an Adenovirus Carrying Endostatin Gene, Enhanced 

Anti-Tumor Effect of Metronomic Chemotherapy with Low 

Dose Cisplatin in a Xenograft Mouse Model for Head and 

Neck Squamous Cell Carcinoma 

Zainal Adhim, Xubin Lin, Wenlin Huang, Tsutomu Nakamura, 

Hiroyuki Yasui, Naoki Otsuki, Ken-ichi Nibu, Masato Fujisawa, 

Toshiro Shirakawa. 

810 

Down-Regulation of Breast Cancer Resistance Protein 

(BCRP) by siRNA Delivery Using Lipid-Substituted Aliphatic 

Polymers 

Hamidreza Montazeri Aliabadi, Breanne Landry, Parvin 

Mahdipoor, Hasan Uludag. 

811 

Experimental Gene Therapy of Nasopharyngeal Carcinoma 

Targeted to Telomerase 

Wen Zhong. 

812 

Design and Hydrodynamic Gene Transfer of ‘Sticky’ IFNγ 

for Liver-Directed Gene Therapy of Hepatic Metastasis of 


Mitsuru Ando, Yuki Takahashi, Hanae Mukumoto, Makiya 

Nishikawa, Yoshihiko Watanabe, Yoshinobu Takakura. 

813 

Cytokine-Based Log-Scale Expansion of Functional Human 

Dendritic Cells from PBMCs 

Yui Harada, Satoru Saito, Yosuke Morodomi, Kumi Yoshida, 

Tomohiko Ichikawa, Yoshikazu Yonemitsu. 

814 

A New Method To Develop Genetically Modified Lung 

Cancer Stem Cells 

Feridoun Karimi-Busheri, Victoria Zadorozhny, Ali Haghighi, 

Daniel L. Shawler, Habib Fakhrai. 

815 

miRNA from Tumor-Associated Macrophages as Serum 

Biomarkers for Ovarian Cancer 

Jonas Persson, Ines Beyer, Nicole Urban, Charles Drescher, 

Andre Lieber. 

816 

Increased Invasiveness and Host Vessels Co-Option after 

15-LO-1 and HSV-tk Combination Gene Therapy in Rat 

Glioma Model 

Agnieszka Pacholska, Haritha Samaranayake, Jere 

Pikkarainen, Farizan Ahmad, Thomas Wirth, Seppo 


817 

Effective Sensitization of Paclitaxel-Resistant Colorectal 

Cancer Cells by New Cationic Micelle-Based Combined 

Delivery of Paclitaxel and XIAP siRNA 

Yeon Lim Jang, Ui Jeong Yun, Min Sang Lee, Myung Goo Kim, 

Su Young Chae, Dong-Gyu Jo, Jae Hyung Park, Ji Hoon Jeong. 

818 

c-Cbl shRNA-Expressing Adenovirus Sensitizes TRAIL- 

Induced Apoptosis with Less Side Effects 

So Y. Kim, Bo K. Sun, Seeun Oh, Dongho Kim, Joo-Hang Kim, 

Jae J. Song. 

819 

PEI-CyD-FA Coated Adenovirus as an Effective and Safe 

Gene Delivery Vector 

Hong Yao, Julia J. Li, Wai S. Poon, Hsiang-fu Kung, Xiu Wu 

Bian, Marie C. Lin. 




6:15 PM – 8:15 PM 

Room: Hall 4B 



820 

Tolerance Induction towards Protein Therapy Using 

Autologous Dendritic Cells 

Gautam Sule, Masataka Suzuki, Racel Cela, John Rodgers, 

Brendan Lee. 

821 

Rescue of the Bleeding Diathesis in Severe Von Willebrand 

Disease Using Lentiviral Gene Transfer 

Jonathan B. Rosenberg, Bishnu P. De, Lan Wang, Stephen M. 

Kaminsky, Ronald G. Crystal. 

822 

Blood Outgrowth Endothelial Cells for Gene Therapy of 

Rheumatoid Arthritis 

Jeana Zacharias, Jennifer L. Auger, Liming Milbauer, Robert P. 

Hebbel, Bryce A. Binstadt, Nicola J. Philpott. 

823 

Factor IX Expression in Skeletal Muscle of a Subject with 

Severe Hemophilia B Ten Years after AAV Gene Transfer 

George Buchlis, Gregory M. Podsakoff, Antonetta Radu, Alan 

W. Flake, Federico Mingozzi, Katherine A. High. 

824 

Recombinant AAV2-Mediated β-Globin Expression in 

Human Fetal Hematopoietic Cells from the Aborted Fetus 

with β-Thalassemia 

Jing Tian, Feng Wang, Jin-feng Xue, Fei Zhou, Liu-jiang Song, 

Meng-qun Tan. 

825 

Immune Modulation in Hemophilia A Mice Using Anti- 

CD20 and Liver-Directed Gene Transfer 

Brandon K. Sack, Babak Moghimi, Roland W. Herzog. 

826 

Differential Lineage Transduction Results in Limited FVIII 

Expression after Ex Vivo Modification of Hematopoietic 

Progenitor Cells 

Jennifer M. Johnston, Christopher B. Doering, H. Trent 

Spencer. 

827 

Development of Novel AAV Vectors for Potential In Vivo 

Gene transfer to Hematopoietic Cells in Bone Marrow 

Mengxin Li, Qin Su, Ran He, Hongwei Zhang, Terry Flotte, 

Arun Srivastava, Guangping Gao, Li Zhong. 

828 

In Vivo Gene Therapy of Hemophilia A Mice by Intra- 

Bone Marrow Injection of Lentiviral Vectors Containing a 

B-Domain Variant of Human Factor VIII 

Xuefeng Wang, Liping Chen, Andy Chiang, Peiqing Ye, Carol 

H. Miao. 

829 

Evaluation of Liver Gene Therapy by Lentiviral Vectors in a 

Dog Model of Hemophilia B 

Alessio Cantore, Martina Damo, Marco Ranzani, Lucia Sergi 

Sergi, Marina Radrizzani, Francesca Bellintani, Brian Brown, 

Eugenio Montini, Timothy Nichols, Luigi Naldini. 

830 

Targeting B Cells To Express a Tolerogenic Fusion Protein 

Using Pseudotyped Lentiviral Vectors Displaying a Single 

Chain Antibody Against Human CD20 

Ai-Hong (Allan) Zhang, Nana Owusu-Boaitey, Sabrina Kneissl, 

Christian J. Buchholz, David W. Scott. 


BAFF Inhibition by Exon Skipping in Sjögren’s Syndrome 

Nienke Roescher, Jelle Vosters, Ghada Al Saleh, Patrick 

Dreyfus, Sebastien Jacques, Luis Garcia, Gilles Chiocchia, 

Antoine Francoise, Jean Sibilia, Paul Peter Tak, Jay Chiorini, 

Xavier Mariette, Jacques-Eric Gottenberg. 

832 

FIX Gain of Function Mutants Augment Hemophilia B Gene 

Therapy To Allow Minimal AAV Vector Exposure 

Paul E. Monahan, Tal Kafri, William Hannah, Tong Gui, 

Junjiang Sun, Thipparat Suwanmanee, Scott W. McPhee, R. 

Jude Samulski. 

833 

Valproic Acid-Mediated Retention of High Level Expression 

of Potential Hematopoietic Stem Cell Markers Does Not 

Correlate with Enhancement of Engraftment 

Randall K. Merling, KuyLee Han, Colin L. Sweeney, Hongmei 

Wang, Joseph Marcotte, Gilda F. Linton, Sherry M. Walker, 

Uimook Choi, Harry L. Malech. 


834 

Specific Targeting of Prostate Cancer by an Aptamer-siRNA 

Chimera 

Craig A. Howell, William M. Rockey, Xiu Y. Liu, Daniel Vaena, 

Paloma H. Giangrande. 

835 

Cell Penetrating Peptide-Mediated Systemic siRNA Delivery 

to the Liver 

Jun Yamauchi, Yasuhiro Hayashi, Khalil A. Ikramy, Hidetaka 

Akita, Kazuaki Kajimoto, Hideyoshi Harashima. 


Saturday, May 21


146 



6:15 PM – 8:15 PM 

Room: Hall 4B 


836 

Subcutaneous Delivery of Hepatocyte Targeted Sub-50 nm 

Nanoencapsulated siRNA Mediates Gene Silencing 

B. T. Kren, D. Tolbot, V. Korman, G. M. Unger. 

837 (MOVED TO POSTER SESSION II AFTER ABSTRACT 570) 

Improving the Specificity of RNAi-Based Therapeutics for 

Huntington’s Disease 

Ryan L. Boudreau, Jodi L. McBride, Ryan M. Spengler, Beverly 

L. Davidson. 

838 

Flexible Cationic Lipids for siRNA Delivery 

Jeff Sparks, Gregory Slobodkin, Richard T. Congo, David 

Ulkoski, Majed Matar, Angela Rea-Ramsey, Casey Pence, 

Jennifer Rice, Diane McClure, Kevin J. Polach, Elaine 

Brunhoeber, Leslie Wilkinson, Khursheed Anwer, Jason G. 

Fewell. 

839 

Smart Nanoparticle for MMP-7 Proximity-Activated siRNA 

Delivery 

Hongmei Li, Christopher E. Nelson, Todd D. Giorgio, Craig L. 

Duvall. 

840 

Experimental and Computational Design of Combinatorial 

RNAi Therapies Against HIV 

Priya S. Shah, Sharon Aviran, Nhung P. Pham, Adam P. Arkin, 

David V. Schaffer. 

841 

Engineered Scaffold for Sustained, Local siRNA Delivery 

Christopher E. Nelson, Mukesh K. Gupta, Elizabeth J. Adolph, 

Scott A. Guelcher, Craig L. Duvall. 

842 

RNAi Therapy for Polyglutamine Expansion Disorders 

Pavitra Narasimha, Ryan L. Boudreau, Ryan M. Spengler, 

Beverly L. Davidson. 

843 

Combining Tumor-Targeting, Gene Silencing, and siRNA- 

Mediated Cytokine Induction in a Viral Capsid-Derived 

Nanoparticle 

David Chu, Jae Youn Hwang, Jay Lubow, Altan Rentsendorj, 

Lali Medina-Kauwe. 

844 

The Effect of Nanofiber Topography on Astrocyte Behavior 

In Vitro and the Potential Application for siRNA Delivery for 

CNS Regeneration 

Haoqing Cao, Guillaume Marcy, Eyleen Lay Keow Goh, Jun 

Wang, Sing Yian Chew. 

845 

Inhibition of PCBP2 Reverses the Fibrogenic Effect of 

Alcohol on Hepatic Stellate Cells 

Ravi S. Shukla, Shaoying Wang, Kun Cheng. 

846 

Expanded CAG Repeats Enhance the Production of a 

Pathogenic Cav2.1 Splice Variant That Can Be Selectively 

Targeted Using RNAi 

Wei-Ling Tsou, Bing-Weng Soong, Henry L. Paulson, Edgardo 

Rodriguez-Lebron. 

847 

Apolipoprotein B Knock-Down by AAV-Delivered sh/miRNA 

Lowers Plasma Cholesterol in Mice 

Piotr Maczuga, Annemart Koornneef, Richard van 

Logtenstein, Florie Borel, Bas Blits, Sander van Deventer, 

Harald Petry, Pavlina Konstantinova. 

848 

Double-Stranded Let-7 Mimics, Potential Candidates for 

Cancer Gene Therapy 

Qizhao Wang, Chao Lu, Weidong Xiao, Ruian Xu. 

849 

Effective in vivo silencing for therapeutic application using 

serum stabilized, non-immunogenic and potent chemically 

modified siRNAs 

Nitin Puri, Chris Burnett, Sasha Vlassov, Angie Cheng, Varun 

Bagai, Xavier de Mollerat du Jeu, Kristin Wiederholt, Susan 

Magdaleno. 

850 

RNA Interference Effects on Neuronal Nitric Oxide Synthase 

Enzyme (nNOS) from Glioma Cells in Culture 

Fernando F. B. Resende, Elaine Del Bel, Luis Pardo, Walter 

Stühmer, Ricardo Titze-de-Almeida. 




6:15 PM – 8:15 PM 

Room: Hall 4B 

851 

Silencing the Expression of the alpha Isoform of the 

Neuronal Nitric Oxide Synthase Enzyme (nNOS) in 

Neuroblastoma Cells by Synthetic Double-Stranded siRNA 

Linus Q. Pereira, Luciana M. Klüppel, Nádia R. Ferreira, 

Simoneide S. Silva, Luis Pardo, Walter Stühmer, Elaine Del Bel, 

Ricardo Titze-de-Almeida. 

Stem Cell Therapies III 

852 

Similarities between Cancer Stem Cells and Induced 

Pluripotent Stem Cells 

Ruan van Rensburg, Robert Strauss, Ines Beyer, Oleg 

Denisenko, Karol Bomsztyk, Andre Lieber. 

853 

Transcriptional Analysis of Human Embryonic Stem 

Cells and Vascular Endothelial Cells Derived Via Directed 

Differentiation 

Lynsey Howard, Nicole M. Kane, Martin W. McBride, John 

McClure, Peter D. Adams, Tony McBryan, Graeme Milligan, 

Andrew H. Baker. 

854 

An In Vitro Analog of the Primitive Streak To Derive High- 

Purity Definitive Endoderm Lineages Uncontaminated by 

Undifferentiated Cells 

Larissa Agapova, Richard West, Alina Ostrowska, Ruslan 

Semechkin, Vladimir Agapov, Irina Turovets, Olga Kochetkova, 

Jeffrey Janus, Andrey Semechkin, Nikolay Turovets. 

855 

Peptide Based Bone Marrow Targeting of Cord Blood Cells 

Thomas J. Kean, James E. Dennis. 


857 

Donor Dependency of Integrin-and Chemokine Mediated 

Adhesion Activation in Human Mesenchymal Stromal Cells 

(MSCs) 

Felicia Ciuculescu, Melanie Giesen, Victoria Lang, Reinhard 

Henschler. 

858 

Human Liver Endothelial Cells, but Not Macrovascular or 

Microvascular Endothelial Cells, Can Inhabit the Mouse 

Liver Sinusoidal Endothelial Niche 

Ebtisam E. l. Filali, Johan Hiralall, Donna B. Stolz, Jurgen 

Seppen. 

859 

Immune Modulation and Control of GvHD by Mesenchymal 

Stem Cells 

Lung-Ji Chang, Yin Liang, Weng Hang Ho, Jian-Ping Zhang, 

Jing-Bo Wang, Tong Wu, Chun-Rong Tong, Lu-Jia Dong, Dao- 

Pei Lu. 

860 

Highly Efficient Neural Lineage Induction and Generation 

of Neural Progenitor Cells Via an Aggrewell Embryoid 

Body Formation System with a Novel Neural Induction 

Medium 

Alexandra A. Blak, Jennifer Antonchuk, Eileen Yoshida, Mark 

Fairy, Terry E. Thomas, Allen C. Eaves, Sharon A. Louis. 

861 

Oncogenic Risk of Induced Pluriptent Stem Cells 

Established from Somatic Cells with Chromosome 

Instability 

Saori Yamaguchi, Tomotoshi Marumoto, Takenobu Nii, 

Hirotaka Kawano, Jiyuan Liao, Yoko Nagai, Michiyo Okada, 

Atsushi Takahashi, Hiroyuki Inoue, Erika Sasaki, Shinji Okano, 

Yoshie Miura, Kenzaburo Tani. 

862 

Hypoxia Inhibits Senescence and Maintains Mesenchymal 

Stem Cell Properties through Downregulation of E2A-p21 

by HIF-TWIST 

Chih-Chien Tsai, Yann-Jang Chen, Tu-Lai Yew, Shih-Chieh 

Hung. 

863 

IPS Technology and It’s Implications for Gene and Cell 


Duanqing Pei. 

864 

A GMP-Compliant Process for the Scale-Up and Large Scale 

Banking of Human Embryonic Stem Cells 

Lara J. Ausubel, Patricia Lopez, Rui-Lin Wu, Tania Aguilar, 

Jing Chai, Wei Dang, Patricia Huang, Rafat Khan, Derek Kong, 

Robbin Wesselschmidt, David Hsu, Larry Couture. 

865 

Safeguarding Nonhuman Primate iPS Cells with Suicide 

Genes 

Bonan Zhong, Korashon L. Watts, Martin E. Wohlfahrt, 

Jennifer E. Adair, Joerg Enssle, Hans-Peter Kiem. 

866 

Bone Marrow Derived Stem Cells Involved in Regeneration 

of Epithelial Cells through Cell Fusion 

Yi-ling Hsu, Xianghui He, Wei Wei, Zhixiang Zhang, Liwei Zhu. 


Saturday, May 21


148 



6:15 PM – 8:15 PM 

Room: Hall 4B 

Late Abstracts III 

911 

Pancreatic Cancer-Selective Adenovirus Vector with 

Redesigned AB-loop Isolated via Adenovirus Library 

Screening Shows Specificity to Mesothelin Expressing Cells 

Yoshiaki Miura, Eric Brown, Julia Davydova, Masato 

Yamamoto. 

912 

Retargeting of Adenovirus to Breast Cancer 

Shilpa Bhatia, Ana Nedeljkovic-Kurepa, Yoshi Odaka, Angel A. 

Rivera, Alexander Perebeov, David T. Curiel, J. Michael Mathis. 

913 

Targeting Tumor Heterogeneity in Glioblastoma: Bispecific 

T Cells Exhibit Enhanced Effector Functions and Offset 

Antigen Loss Escape Variants 

Meenakshi Hegde, Eric Yvon, Aidin Ashoori, Malini 

Mukherjee, Kevin KH Chow, Claudia Gerken, Vita S Salsman, 

Helen E Heslop, Stephen Gottschalk, Nabil Ahmed. 


Intracellular Trafficking of a Histone-Mimetic Polyplex to 

Promote Nucleus-Specific Self-Unpackaging 

Meghan J. Reilly, John D. Larsen, Millicent O. Sullivan. 

915 

Neural Stem Cell-Based Carrier Enhances Antitumor 

Activity of Oncolytic Adenovirus and Prolongs Survival in a 

Orthotopic Murine Model of Human Glioblastoma 

Atique U. Ahmed, Nikita G. Alexiades, Bart Thaci, Yu Han, Ilya 

I. Ulasov, Maciej S. Lesniak. 

916 

A Recombinant Vaccinia Virus-Based T Cell Vaccine Against 

Influenza Virus Reduces Lung Viral Load Upon Virus 

Challenge 

Alan G. Goodman, Susana Guerra, Aneesh Vijayan, Paul P. 

Heinen, Carlos Oscar S. Sorzano, Mariano Esteban. 

917 

Engineering Attenuated Salmonella Typhimurium for 

Selective Targeting and Gene Expression in Myocardial 

Infarction 

Uyenchi N. Le, Jihwa Chung, Dukmi Kim, Jung-Joon Min. 

918 

Combined Effects of Hematopoietic Progenitor Cell 

Mobilization from Bone Marrow by G-CSF and AMD3100, 

and Chemotaxis into the Brain Using SDF-1α in an 

Alzheimer`s Disease Mouse Model 

Hee Kyung Jin, Jae-Sung Bae. 

919 

Effect of a Novel Peptide Antagonizing NF-κB p65 on 

Maturation of Dendritic Cells and Collagen-Induced 

Arthritis in Mice 

Huaping Liang, Yanhua Li, Xia Fan, Chun Zhang. 

920 

Over Expression of Bcl-2 Enhance Preservation of Spleen 

Cytoarchitecture and Promotes Lymphocyte Proliferation 

Francisco Martínez-F, JL Ventura-Gallegos, L Covarrubias, 

Erendira Estrada-V, Epifanio Cruz, M Legorreta–Herrera, A 

Zentella-Dehesa. 

921 

AAV Transduction Reduces Adult Neurogenesis in 

Hippocampus in Mice 

Wenting Chang, Shinghua Ding. 

922 

Development of DNA Vaccine against Avian Influenza A 

Virus (H5N1) 

Shaheen Ahmed, Tatiana K. Bronich, Alexander V. Kabanov. 

923 

Electoporation-Mediated Kallistatin Gene Therapy 

Protected TNBS-Induced Colitis and CCl4-Induced Liver 

Fibrosis In Vivo 

Yong Diao, Yinghui Lv, Qizhao Wang, Ruian Xu. 

924 

Mesenchymal Stem Cell-Conditioned Medium Facilitates 

Angiogenesis and Fracture Healing in Diabetic Rats 

Chien-Yuan Wang, Hsiao-Bai Yang, Ling-Lan Chen, Chih-Chien 

Tsai, Kuo-Shu Tsai, Tu-Lai Yew, Yi-Hsuan Kao, Shih-Chieh 

Hung, Ying-Jiin Wang. 

925 

Inhibition of PI3K-AKT Pathway Promotes Hemangioblasts 

Differentiation of Common Marmoset Embryonic Stem 

Cells. 

Takenobu Nii, Tomotoshi Marumoto, Hirotaka Kawano, Saori 

Yamaguchi, Yoko Nagai, Yoshie Miura, Jiyuan Liao, Mishiyo 

Okada, Kenzaburo Tani. 

926 

siRNA/shRNA Delivery Using Chitosan Derivatives for Lung 

Cancer Therapy 

Hu-Lin Jiang, You-Kyoung Kim, Kyeong-Nam Yu, Seung-Hee 

Chang, Chong-Su Cho, Myung-Haing Cho. 




6:15 PM – 8:15 PM 

Room: Hall 4B 

Late Abstracts III 

927 

Divalent DNA or Subunit Vaccines Against Infectious Bursal 

Disease and Infectious Bronchitis in Chickens 

Ming-Kun Hsieh, Kuang-Chung Chu, Jui-Hung Shine, Cheng- 

Yan Chen, Jin-Lin Liao. 

928 

Dendrimers as Nanovectors for DNA and siRNA Delivery: 

Promises and Challenges 

Xiaoxuan Liu, Miriam Yammine, Palma Rocchi, Catherine 

Nguyen, Ling Peng. 

929 

Beclin1 Regulates Radiation-Induced Osteopontin in 

Human Lung Cancer Cells 

Seung-Hee Chang, Arash Minai-Tehrani, Ji-Young Shin, Sung- 

Jin Park, Ji-Eun Kim, Kyeong-Nam Yu, Myung-Haing Cho. 

930 

Study on Mutations of Pre-S/S Protein of Occult Hepatitis B 

Virus from Blood Donors 

Xin Zheng, Baocheng Yang, Weigang Zhu, Liang Lu, Xianlin 

Ye, Chengyao Li. 

931 

Nucleic Acid Amplification Testing (NAT) for Blood 

Screening in Shenzhen, China 

XL Ye, BC Yang, WG Zhu, X Zheng. 

932 

A 48 Year Old Woman with a Rare Case of a Midline 

Destructive Disease Presenting as Having Both Midline and 

Nonmidline Lesions – A Case Report 

Stephanie. Fernandez, Felycette G. Lapus, Marie Yvette Barez. 


Saturday, May 21

150 

Abstract Author Index 

A 

Aaronson, Naomi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Aartsma-Rus, Annemieke. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765 

Abbasi, Meysam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 

Abdul-Razak, Hayder H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Abel, Tobias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386 

Abramihina, Tatiana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 

Abramowitz, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725 

Adachi, Kei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126, 397, 407, 659 

Adair, Jennifer E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .191, 342, 865 

Adam, Virginie S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214, 801 

Adamo, Richard F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 738 

Adamo, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 733 

Adams, Matthew S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153 

Adams, Peter D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 853 

Adão-Novaes, Juliana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 753 

Adhim, Zainal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Adjali, Oumeya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 

Adler, Cheryl . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 

Adolph, Elizabeth J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 841 

Afia, Larbi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133, 551 

AFM-Sponsored Duchenne Consortium, The . . . . . . . . . . . . . . . 72 

Agapov, Vladimir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 854 

Agapova, Larissa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 854 

Agbandje-McKenna, Mavis . . . . . . . . . . .1, 327, 328, 329, 330, 332, 

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 374, 396, 402, 670 

Agdelo, Carlos G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581 

Aggen, David H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356 

Aguilar Salegio, Ernesto . . . . . . . . . . . . . . . . . . . . . . . . . .206, 647, 746 

Aguilar, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Aguilar, Kiefer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494 

Aguilar, Laura K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Aguilar, Tania . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Aguilar-Cordova, Estuardo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Ahlroth, Mervi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 

Ahmad, Farizan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 816 

Ahmad, Ferhaan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659 

Ahmed, Atique U. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 915 

Ahmed, Nabil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27, 496, 781, 913 

Ahmed, Seemin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555, 649 

Ahmed, Shaheen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 922 

Ahn, Miwon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889 

Ahouansou, Ornella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Ahtiainen, Laura. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295, 795 

Aiuti, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264, 267, 604, 605 

Aizawa, Emi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315 

Akabarpur, Mahzad . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290 

Akin, Ali . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535 

Akita, Hidetaka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 835 

Akiyoshi, Kazunari . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434 

Al Saleh, Ghada . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Aladjem, Mirit I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302 

Alameh, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 881 

Alexiades, Nikita G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 915 

Alfano, Lindsay N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768 

Alfaro, Carlos . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Al-Hendy, Ayman. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243 

Ali, Rehan S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 541 

Aliabadi, Hamid M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 

Alkhatib, Ghalib . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 

Allay, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Allay, James A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 587 

Allen, Cory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365 

Allen, James M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466 

Allen, James. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 

Allgayer, Heike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Alluin, Jessica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559 

Almeida, Luciana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428 

Almeida-Porada, G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873 

Almutairi, Adah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436 

Altomonte, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793 

Alton, Eric W. F. W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165, 272 

Alton, Eric W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108 

Alvarez-Breckenridge, Christopher. . . . . . . . . . . . . . . . . . . . . . . . . 362 

Alzadeh, Gabrielle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .59, 788 

Ambach, Dianna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Ambrosi, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264 

Ameli, Masoud . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 897 

Amendola, Mario. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 

Ameres, Stefan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555 

Amirache, Fouzia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876, 893 

Amouri, Rim. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

An, Dong Sung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 

Anagnostopoulos, Achilles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Andel, J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Anderson, Athena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489 

Anderson, Joseph S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 

Anderson, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496 

Andersson, Helen A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 

Ando, Dale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544, 598 

Ando, Mitsuru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 812 

Andreeff, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533 

Anegon, Ignacio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 

Ang, Sonny O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353 

Ang, Sonny. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234, 500 

Ang, SooFan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Angell-Manning, Diana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

Angello, John C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 

Anguela, Xavier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Anikster, Yair. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457 

Anne, Moon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599 

Annoni, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 290, 377 

Annunziata, Patrizia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 665 

Anson, Don S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273, 281 

Antin, Joseph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 



Antonchuk, Jennifer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 860 

Antoniou, Michael N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 

Anwer, Khursheed. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Aoki, Kazunori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235, 674 

Aoki, Yoshitsugu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558 

Aoyagi, Yasuyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 

Aoyagi, Yutaka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 705 

Appelt, Jens-Uwe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32, 46 

Appelt, U. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 

Aramaki, Yukihiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483 

Aras, Rahul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Arbuthnot, Patrick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .208, 556, 563 

Ardaiz, Nuria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776 

Arens, Anne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223, 632 

Ariga, Masamichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 721 

Arkin, Adam P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840 

Armendariz, Juan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 681 

Armendariz-Borunda, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420 

Armentano, Donna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Armstrong, Adam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311 

Armstrong, Leonard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 525 

Arndt, Stefanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506 

Arnett, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 475, 762 

Arnoud, Sylvain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 576 

Aronovich, Elena L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 

Arsenakis, Minas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Arthur, Julian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646 

Artus, Alexandre. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 383, 389 

Arulmuthu, Eugene R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 450 

Arumugam, Paritha I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613 

Arya, Suresh K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217 

Asad, Sabah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 897 

Asada, Sakiyo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 

Asakawa, Nagisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 754 

Ascenzi, Mary A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Ashoori, Aidin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496, 913 

Aslanidi, George V.. . . . . . . . . . . . . . . . . . . . . . . . . . . 330, 402, 406, 619 

Aso, Masayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 

Asokan, Aravind. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328, 393 

Assi, Hikmat H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 510 

Assi, Hikmat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 788 

Astolfi, Melina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 699 

Astrakhan, Alexander. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260, 349 

Asuri, Prashanth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122 

Athanasiou, Evangelia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Atkinson, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669 

Atkinson, Peter W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 

Au, Betty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 551 

Au, Joyce. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640, 678 

Aubourg, Patrick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42, 195, 611 

Aubrecht, Jiri . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Audit, Muriel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .51, 589 

Augat, Peter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469, 767 

Auger, Jennifer L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 822 

Auricchio, Alberto . . . . . . . . . . . . . . . . . . . . . . . . . . . 454, 542, 665, 722 

Ausubel, Lara J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Avanessian, Bella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773 

Aviran, Sharon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840 

B 

Baban, Chwanrow. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535 

Baccarini, Alessia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 

Badding, Melissa A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173 

Badea, Ildiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 182 

Badie, Behnam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351 

Bading, James. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351 

Bae, Hyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 856 

Bae, Jae-Sung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 918 

Baehr, Wolfgang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199 

Baert, Miranda R. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Bagai, Varun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849 

Bagarazzi, Mark. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

Bai, Henri. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719 

Bai, Henry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 726 

Bai, Shoumei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

Baiker, Armin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 413 

Baker, Andrew H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6, 727, 853 

Baker, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 

Baker, Henry J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646 

Baker, Matthew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 

Bakker, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133, 551 

Balaj, Leonora . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 

Balasubramanian, Karthika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787 

Baldo, Guilherme. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .718, 719, 726 

Bali, Deeksha S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338 

Ball, Claudia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Ballabio, Andrea. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722 

Baltimore, D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Baltimore, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494 

Ban, Hiroshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 577 

Bandyopadhyay, Sarmistha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561 

Banfi, Sandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542, 665 

Bangio, Livnat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 885 

Bankiewicz, Krystof S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39, 206, 746 

Bankiewicz, Krystof . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647 

Banks, Glen B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466, 472 

Banks, Glen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 

Banks, Kathleen G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Barayni, Lajos. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 592 

Barber, Glen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360, 888 

Barez, Marie Yvette . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 932 

Baricordi, Cristina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264 

Barker, Jenny . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 634 

Barnay-Toutain, Frédéric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589 

Barnett, Nicholas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787 

Barnett, Rebecca C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280 


152 


Barrera-L, Araceli . . . . . . . . . . . . . . . . . . . . . . . . . . . . 886, 887, 894, 895 

Barry, Elizabeth A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 656 

Barry, Michael A.. . . . . . . . . . . . . . . . . . . . . . . 8, 60, 209, 414, 488, 658 

Bartel, Maya J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Bartel, Melissa A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122 

Bartholomae, Cynthia C.. . . . . . . . . . . . .42, 264, 607, 610, 611, 632 

Bartlett, David L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599 

Bartlett, Jeffrey S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662 

Barve, Minal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Basner-Tschakarjan, E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Basu, Gaurav . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 708, 711 

Batshaw, Mark. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340 

Bauer, Gerhard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 

Bauer, Jr., Thomas R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258 

Bauer, Thomas R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613 

Baum, Bruce J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642, 657 

Baum, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41, 348, 369 

Bear, Adham S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .84, 779 

Beard, Brian C.. . . . . . . . . . . . . . . . . . . . . .251, 257, 342, 344, 485, 637 

Beattie, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 

Beaudet, Arthur . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3, 45, 277 

Bechtle, Marina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394 

Becker, Pamela S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191 

Bedayat, Arash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Bedell, Cynthia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Begum, Laila . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477 

Behin, Anthony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Behlke, Mark A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271 

Behr, Jean-Paul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638 

Behr, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 

Beletkaia, Elena A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Beley, Cyriaque. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 661 

Bell, Christie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 326 

Bell, Jason B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 

Bell, John C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 

Bell, Peter . . . . . . . . . . . . . . . . . . . . .102, 186, 196, 292, 326, 340, 621 

Bellezza, Christine A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Bellintani, Francesca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 829 

Beltejar, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 676 

Belur, Lalitha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 702 

Ben Assaf, Lior. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320 

Ben David, Shiran . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 370 

Benedicenti, Fabrizio . . . . . . . . . . . . . . . . . . . . . . . . 606, 607, 610, 611 

Benito, Alberto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Benjamin, Shimon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 370 

Bennett, Antoinette D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670 

Bennett, C. Frank . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Bennett, Jean . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196, 600 

Bennett, William. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336 

Bennicelli, Jeannette . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600 

Benrashid, Ehsan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 567 

Benten, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Benveniste, Olivier. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Bergen, Jamie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 654 

Berger, Mitchel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Bernstein, Wendy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Berraondo, Pedro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776 

Berretti, Silvia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Berry, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9 

Bertin, Terry K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 

Bertolotti, Roger. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 324, 583 

Bertoni, Carmen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .71, 470 

Bertrand, Claudia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5 

Betts, Michael R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 

Betz, Oliver B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .469, 482, 767 

Betz, Volker M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .469, 482, 767 

Bevan, Adam K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392 

Beyer, Ines . . . . . . . . . . . . . . . 2, 18, 78, 135, 226, 497, 578, 815, 852 

Beyer, Janine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 

Bezuidenhout, Abraham J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Bezuidenhout, Deon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629 

Bhagwat, Anand . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Bhakta, Vipul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529 

Bharathan, Mini . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883 

Bhatia, Shilpa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530, 912 

Bhaumik, Srabani. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644, 645 

Bi, Meixia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883, 899 

Bian, Ang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680 

Bian, Xiu Wu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819 

Bian, Yixin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218 

Biasco, Luca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264, 604 

Biassoni, Lorenzo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 

Biehl, Martin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 594 

Biffi, Alessandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604, 611 

Bigey, P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Bigg, Paul W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719, 726 

Bigger, Brian W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336 

Bigger, Brian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 716 

Biju, K. C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202 

Bikram, Malavosklish . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735 

Bilchuk, Natalia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153 

Binder, Gwendolyn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Bindra, Ranjit S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 

Binley, Katie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

Binstadt, Bryce A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 822 

Bird, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338, 339 

Bird, Andy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289 

Bischof, Daniela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 590 

Bischoff, Loraine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334 

Biswas, Arijit. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 

Blackmon, Shanda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496 

Blak, Alexandra A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 860 

Blasczyk, Rainer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Blau, Anthony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 741 

Blau, C. Anthony. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251, 426 

Blazar, Bruce R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 686 



Bleier, Stephanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Blevins, Katherine S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159 

Blits, Bas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 564, 847 

Block, Gregory J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531 

Bloomston, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Boccalatte, Francesco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94 

Boelens, JaapJan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 715 

Bogan, Brooke T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Bogan, Dan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 

Bogan, Janet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 

Böhm, Marie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Boisgérault, Florence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Boisvert, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404 

Boivert, Sébastien . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428 

Bolcato-Bellemin, Anne-Laure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638 

Bollard, Catherine M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20, 496 

Bolt, Livia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 

Bolyard, Chelsea M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662 

Bomsztyk, Karol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 578, 852 

Bond, Wesley S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 

Bondale, Niyati . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 789 

Bondanza, Attilio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 498, 605, 785 

Bone, Robert N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 

Bonini, Chiara . . . . . . . . . . . . . . . . . . . . . . . . . . . .80, 498, 605, 631, 785 

Bonnet, Marie-Elise. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638 

Bonvento, Gilles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Bordignon, Claudio. . . . . . . . . . . . . . . . . . . . . . . . . . 498, 588, 605, 785 

Borel, Florie . . . . . . . . . . . . . . . . . . . . . . . . . . . . 562, 564, 566, 569, 847 

Borquez-Ojeda, Oriana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Bortolanza, Sergia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 757 

Borzone, Roberta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460 

Bosch, Assumpció. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417 

Bosma, Bas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 

Bossow, Sascha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514, 521, 528, 798 

Bosticardo, Marita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Botbol, Yaïr . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389 

Boudreau, Ryan L. . . . . . . . . . . . . . . . . . . . . . . . . . . . 198, 650, 837, 842 

Boulad, Farid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 

Boulet, Sabrina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Boulis, Nicholas M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651, 907 

Bouquet, Celine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Bourget, Lucie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381 

Bovolenta, Chiara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588 

Bowen, Nathan J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 628 

Bowers, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 

Bowersock, Joscelyn E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 

Boyd, Surina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 

Boye, Sanford L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199, 203 

Boye, Shannon E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199 

Boyer, Jean. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

Boyer, Joshua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 

Boyer, Julie L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 653 

Boztug, Kaan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Bradbury, Allison M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194, 646 

Bradshaw, Angela C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6 

Brady, Troy L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 635 

Brady, Troy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9, 266, 621 

Brasil, Sandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 

Brault, Michelle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .260, 349, 687 

Braun, Lyndsey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392 

Brayman, Andrew A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623, 625 

Breakefield, Xandra O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 

Bréaut, Léa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Bredius, Robbert G. M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Breen, Christopher R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727 

Breier, Georg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249 

Breinholt, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3 

Breitbach, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 

Breitbart, Eyal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 885 

Brem, Henry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 

Bremer, William G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 

Brenner, Lara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 591 

Brenner, Malcolm K. . . . . . . . . . . . . . . . . . . . . . . . . . . 20, 496, 503, 513 

Brennig, Sebastian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369 

Brentjens, Renier J. . . . . . . . . . . . . . . . . . . . . . . . . . . 230, 239, 495, 791 

Bridges, Charles R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725 

Bright, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281 

Brigida, Immacolata . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264, 605 

Bringas, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647 

Brisson, Diane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 

Broccoli, Vania. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .93, 631 

Broderick, Jennifer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555 

Broderick, Kate E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 429, 701 

Bronich, Tatiana K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 922 

Brown, Brian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37, 829 

Brown, Christine E. . . . . . . . . . . . . . . . . . . . . . . . . . . 351, 352, 499, 501 

Brown, Eric J. . . . . . . . . . . . . . . . . . . . 58, 146, 241, 525, 673, 674, 911 

Brown, Kyle E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561 

Brown, Matthew T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422 

Brown, Paige K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 

Brown, Sarah M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328, 393 

Brugiere, Pierre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Brugman, Martijn H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348 

Brumbach, Jonathan H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159 

Brunetti-Pierri, Nicola. . . . . . . . . . . . . . . . . . 3, 45, 317, 419, 454, 460 

Brunhoeber, Elaine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Bryant, Kelli D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328, 393 

Bryant, Stacie M. J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 

Bucher-Laurent, Stéphanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589 

Buchholz, Christian J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .110, 386, 830 

Buchlis, George . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 823 

Buckland, Robin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893 

Budzinski, Lisa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Bueren, Juan A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268, 876 

Buffo, Mary Jo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899 

Bujo, Hideaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 


154 


Bukh, Irene. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 

Bulfone, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 610 

Bull, David A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161, 560 

Bunnell, Bruce A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Burge, Christopher B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561 

Burger, Corinna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670 

Burke, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 

Burke, Kathrin A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314 

Burkholder, Tanya H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258, 346 

Burleyson, Joy R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585 

Burnett, Chris . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849 

Burnett, Ryan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Burns, William R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231 

Buscail, Louis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 878, 902 

Buschmann, Michael D. . . . . . . . . . . . . . . . . . . . . . . . . . .699, 881, 904 

Bushman, Frederic D. . . . . . . . . . . . . . . . . . . . . . . . . . . 9, 612, 621, 635 

Butterfield, Lisa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899 

Butts, Charlotte. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 593 

Byers, Peter H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 474 

Byrd, Tiara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 

Byrne, Barry J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104, 131, 458, 901 

Byrne, William L . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 906 

Byrnes, Andrew P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 

C 

Cafferata, Eduardo G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238, 519 

Cai, Ying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 597 

Caizergues, Didier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Calcedo, Roberto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19, 108, 185, 186 

Calos, Michele P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368 

Camisa, Barbara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .80, 785 

Campbell, D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Campbell, Katherine J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 

Can, Wu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319 

Candolfi, Marianela. . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 787, 788, 789 

Candotti, Fabio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 

Canevari, Silvana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 782 

Cannon, Paula M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .99, 314 

Cantore, Alessio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .377, 610, 829 

Cantz, Tobias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369 

Cao, Haoqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844 

Cao, Hong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 755 

Cao, Lan-Feng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .99, 586 

Cao, Phoung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 306 

Capella-Gonzalez, Cristina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 676 

Capo, Valentina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267 

Capotondo, Alessia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 611 

Carbajo, Rosangela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774 

Carbone, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 653 

Carbone, Larry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Carlier, Pierre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51, 72 

Carlucci, Marie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

Carnathan, Diane G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 

Carney, Gael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256 

Carpenter, Melissa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 579 

Carpenter, Susanne G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Carpentier, André C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 

Carr, Bob . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 595 

Carrer, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 532 

Carrillo-Carrasco, Nuria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453 

Carroll, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Carruthers, Katherine H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 624 

Carson, Joshua S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678 

Carson, Joshua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Carter, Bob S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 

Cartier, Nathalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42, 195, 611 

Caruso, Hillary G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234 

Carvalho, Leonardo Pinto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742 

Casiraghi, Miriam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Casorati, Giulia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498 

Cassani, Barbara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 254 

Castello, Raffaele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460 

Castiello, Maria Carmina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Castle, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618 

Castleton, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 

Castro, Maria G.. . . . . . . . . . . . . . . . . 59, 509, 510, 784, 787, 788, 789 

Castro-Perez, Jose . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Casucci, Monica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 785 

Cataldi, Marcela P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 616 

Cathomen, Toni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 

Cattaneo, Roberto. . . . . . . . . . . . . . . . . . . . . . . . . . . 514, 515, 517, 521 

Cattoglio, Claudia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298, 612 

Causton, Benjamin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272 

Cavazza, Alessia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98 

Cavazzana-Calvo, Marina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41, 42 

Cayer, Marie-Pierre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5 

Cédrone, Frédéric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 576 

Cela, Racel G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 

Cela, Racel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 820 

Cemazar, Maja. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448, 540 

Cerio, Rebecca J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875 

Cerullo, Vincenzo. . . . . . . . . . . . . . . . . . . . . . . . . .55, 77, 295, 478, 795 

Cesana, Daniela . . . . . . . . . . . . . . . . . . . .383, 606, 607, 610, 611, 631 

Cesani, Martina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 611 

Cha, Min-Ji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 740 

Chada, Sunil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883 

Chae, Su Young . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166, 817 

Chai, Jing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Chakkaramakkil, Santhosh V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 388 

Chamberlain, Jeffrey S. . . . . . .36, 76, 466, 472, 475, 762, 763, 770 

Chamberlain, Joel R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 757 

Champlin, Richard E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26, 353 

Chan, Chia-Ling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171 

Chan, Fung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Chan, Jerry K. Y.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 

Chan, Jerry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 



Chan, Robert C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513 

Chan, Yiumo M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468 

Chanda, Diptiman. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615 

Chande, Ajit G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 388 

Chandler, Randy J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452, 453 

Chandrasekaran, Suma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453 

Chang, Jong Wook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580 

Chang, Judy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Chang, Kai-Hsin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 

Chang, Lung-Ji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .211, 724, 859 

Chang, Seung-Hee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .909, 926, 929 

Chang, Wen C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352 

Chang, Wen-Chung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 

Chang, Wenting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 921 

Chang, Yu-Han . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 

Chao, Miao-Fen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 

Chapdelaine, Pierre. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428 

Chapman, Robert L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 751 

Charan, Rakshita. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 479 

Charrier, Sabine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589 

Chatterjee, Saswati . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .128, 329, 663 

Chauhan, Hemangina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 

Chauveau, Christine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 

Chavez, Christopher L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368 

Chayama, Kazuaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 

Chee, ChitLai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Chekmasova, Alena A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 495 

Chen, Alvin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200 

Chen, Anmin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758, 769 

Chen, Cang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202 

Chen, Cheng-Yan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 927 

Chen, Ching-I . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Chen, Chris Y.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8 

Chen, Chuangfu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218 

Chen, Chun-Hao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640, 678 

Chen, Chunlian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 

Chen, Dexi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 672 

Chen, Dong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242, 516 

Chen, Hannah. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412 

Chen, Heng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680 

Chen, Irvin S. Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609 

Chen, Jianzhu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 

Chen, Jie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318 

Chen, Jimmy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 897 

Chen, Jinzhong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .437, 438, 700 

Chen, John W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303 

Chen, Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163 

Chen, Kuan-Hung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 547 

Chen, Ling-Lan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 924 

Chen, Liping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .623, 625, 828 

Chen, Lu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232 

Chen, Nanhai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Chen, Qixian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 

Chen, Sheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404 

Chen, ShuJen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 545 

Chen, Vincent C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 550, 579 

Chen, Xiaolan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 

Chen, Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Chen, Yann-Jang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 862 

Chen, Yingchi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 

Chen, Yi-Shen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 547 

Chen, Yun-Wen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 794 

Chen, Zhi-Ying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 424 

Chen, Zhu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Cheng, Angie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849 

Cheng, Binbin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Cheng, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 

Cheng, Kun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845 

Cheng, Linzhao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345 

Cheng, Seng H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85, 165, 201, 205 

Chen-Tsai, Yanru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368 

Cheraï, Mustapha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Cherel, Yan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72, 195, 207, 375 

Chernajovsky, Yuti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238 

Cherqui, Stephanie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 712 

Chervin, Adam S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356 

Cherylene, Plewa A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 671 

Chesnut, Jon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144 

Chester, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361 

Chew, Sing Yian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844 

Chia, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Chiang, Andy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 828 

Chicoine, Louis G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 

Chien, Yin-Hsiu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 724 

Childers, Martine K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 

Chillón, Miguel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417 

Chinnasamy, Nachimuthu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228 

Chiocchia, Gilles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Chiodo, Vince . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 

Chiorini, Jay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Chiorini, John A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .332, 374, 657 

Chiriaco, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267 

Chiu, Fang-Yao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313 

Chivukula, Raghu R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867, 892 

Chiyo, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 764 

Cho, Chong-Su. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909, 926 

Cho, Kyung-Hyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 707 

Cho, Myung-Haing . . . . . . . . . . . . . . . . . . . . . . . . . . 246, 909, 926, 929 

Cho, Su Hee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279, 549 

Choi, Donghoon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 734 

Choi, Eun-Young . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 548 

Choi, Il-Kyu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140, 421 

Choi, Uimook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345, 833 

Chong, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 

Choolani, Mahesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .46, 253 

Chorny, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 733, 738 


156 


Chou, Bin-Kuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345 

Chou, Brian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 174 

Chou, Ho-Yuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 

Chou, Szu-Ting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 

Chou, Tsung-Han. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 

Chow, Kevin K. H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 781, 913 

Christopherson, Peter W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646 

Chu, Ching-Liang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 512 

Chu, Dave. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177 

Chu, David S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65 

Chu, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 174, 843 

Chu, Donald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Chu, Kirk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 331, 487 

Chu, Kon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880 

Chu, Kuang-Chung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 927 

Chu, Victoria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498 

Chuang, Lea-Yea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Chung, Daniel C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600, 667 

Chung, Janet. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 493 

Chung, Jihwa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 917 

Chung, Vincent. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Ciancia, Claire . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 706 

Cicalese, Maria Pia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Ciccone, Carla. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457 

Ciceri, Fabio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .498, 604, 605 

Cichutek, Klaus. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386 

Cieri, Nicoletta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 

Cioffi, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3 

Ciré, Séverine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Cisper, Neil J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504 

Ciuculescu, Felicia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 857 

Clark, K. Reed. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69, 768, 867, 892 

Clark, Robert A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202 

Clay, Timonthy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289 

Clemens, Paula R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74, 476, 479 

Clement, Nathalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 458 

Clifford, Brian C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Clifford, Luke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 597 

Cloer, Caryn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 567 

Cloutier, Denise A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 

Cmielewski, Patricia L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273 

Coates, Joan R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870 

Cocchiarella, Fabienne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298 

Coffey, Matt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361, 891 

Cohen, Justus B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53, 56 

Cohen, Yael C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 885 

Cohen-Haguenauer, Odile Y. D. . . . . . . . . . . . . . . . . . . . . . . . 383, 389 

Colcher, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 

Coleman, J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Coleman, Jessie S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371 

Colle, Marie-Anne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Colleti, E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873 

Collier, Joel H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 691 

Collins, Sara A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535 

Colombatti, Marco . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295 

Colombo, Daniele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 631 

Coluccio, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 633 

Completo, Gladys . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 

Congo, Richard T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Conlon, Thomas J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 

Conlon, Thomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199, 341 

Connelly, Sheila . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883 

Cooper, Laurence J. N. . . . . . . . . . . . . . . . . . . . 26, 224, 225, 234, 240, 

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353, 354, 500, 508 

Cooper, Mario . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296 

Cooper, Mark J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 748 

Corbeil, Jacques. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428 

Cordelier, Pierre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 878, 902 

Cornetta, Kenneth. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .111, 112, 590 

Cornils, Kerstin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Coronado, Monica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 586 

Corrales, Ricardo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 738 

Cortado, Ruth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 

Corti, Giorgio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .98, 612 

Cosset, François-Loïc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876, 893 

Cossette, Travis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199 

Costa, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876, 893 

Costinean, Stefan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

Cote, Paul J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Cotman, Susan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200 

Cotrim, Ana P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642 

Cots, Dan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417 

Cotte, Julio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Cotugno, Gabriella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 665 

Coukos, George . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 782 

Couture, Larry A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .550, 579, 864 

Couture, Sylvana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 550, 579 

Couturier, A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Covarrubias, L . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 920 

Cox, Nancy R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646 

Coyle, Walter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Cozzi, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Craig, Nancy L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 

Crain, Karen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 484 

Cramer, Frederik. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 905 

Creusat, Gaelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180 

Crombleholme, Timothy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 

Cronin, Michelle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535 

Crooks, Gay M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Crowther, Carol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 563 

Cruz, Conrad R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 

Cruz, Epifanio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 920 

Crystal, Ronald G.. . . . . . . . . 170, 195, 200, 210, 283, 652, 653, 821 

Cuddihy, Andrew R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Cummins, James H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373 

Cunha, Ludmylla C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 570 



CUPID Investigators, on Behalf of the . . . . . . . . . . . . . . . . . . . . . . 601 

Curiel, David T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .138, 238, 243, 519, 

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 886, 887, 894, 895, 912 

Curinga, Gabrielle M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 687 

Curran, Kevin J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230 

Curtin, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 510 

Cuturi, Maria Cristina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 

D 

D’Amico, Donald J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 653 

D’Apuzzo, Massimo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351 

D’Onofrio, Philippe M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544 

Da, Xiaoyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .320, 761, 772 

Dagnaes-Hansen, Frederik. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447 

Dai, Bingbing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492 

Dai, Jian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338 

Dai, Lei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334 

Dai, Yao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Dale, David C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 

Dalferro, Matteo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 728 

Dalkara, D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872 

Dama, Paola. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722 

Damo, Martina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 829 

Danchuk, Svitlana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Dandri, Maura. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Dang, Dianne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277 

Dang, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387 

Dang, Wei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Daood, Molly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74 

Darocha, Sylvie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Darras, Vincent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 699, 881 

Darvish, Babak . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774 

Darvish, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457, 774 

Dasgupta, Anindya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28, 778 

Dasgupta, Asim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609 

Davidoff, Andrew M.. . . . . . . . . . . . . . . . . . . . . . . . . . 46, 262, 587, 602 

Davidson, Beverly L. . . . . . . . . . . . . . . . .198, 271, 650, 837, 842, 870 

Davies, Neil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629 

Davis, Jeremy L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228 

Davis, Pamela B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432 

Davydova, Julia. . . . . . . . . . . . 58, 146, 241, 525, 673, 674, 799, 911 

de Belin, Jackie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

De Bellis, Gianluca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .98, 612 

de Boer, Helen H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .252, 254, 713 

De Geest, Bart. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737 

de Koning, Tom J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 715 

de Kruijf, Marcel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 511 

De Leonibus, Elvira . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722 

de Mollerat du Jeu, Xavier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849 

de Paula, Daisy Bentes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 446 

De Toni, Enrico . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793 

de Wal, Janneke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 

De, Bishnu P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 170, 283, 652, 821 

Dean, David A. . . . . . . . . . . . . . . . . . 12, 107, 149, 173, 280, 704, 905 

Debinski, Waldemar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 

Debyser, Zeger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486 

Deeks, Steven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266, 598 

Del Bel, Elaine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .570, 850, 851 

Del Maschio, Alessandro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605 

Deloron, P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Denapoli, Priscila M. A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742 

Denard, Jerome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 661 

Deneault, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372 

Deniger, Drew C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 224 

Denisenko, Oleg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 578, 852 

Denman, Cecele J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 508 

Denning, Gabriela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 592 

Dennis, James E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 855 

Depuy, Jeannette . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644 

Deschamps, Jack-Yves. . . . . . . . . . . . . . . . . . . . . . . . . . . .195, 207, 375 

Desseaux, Carole . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425, 576 

Desviat, Lourdes R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 

Dewhurst, Stephen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 676 

Dey, Aditi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 

Deyle, David R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384, 474 

Dhaliwal, Anandika. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168 

Dhamne, Hemant R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 388 

Di Cesare, Silvia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267 

Di Matteo, Gigliola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267 

Di Paolo, Nelson C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 409, 491 

Di Pasquale, Giovanni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Di Serio, Clelia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98, 264, 612 

Di Stefano, Bruno. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .93, 631 

Di, Wei Li . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759 

Diaconu, Iulia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55, 77, 295, 795 

Dias, João D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295 

Diaz, Margarita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269 

Diaz, Rosa M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 358 

Diaz, Rosa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361 

Dicembrini, Ilaria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Dichek, David A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 732, 739 

Dick, John E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94 

Dickey, David D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399, 654 

Diehn, Maximilian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 541 

Dighe, Niraja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .46, 253 

DiGiusto, David L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99, 314, 586 

DiMattia, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332 

Ding, Shinghua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 921 

Ding, Wei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 672 

Dingli, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 538 

Diouf, Oumar. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496 

DiRosario, Juliann . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337 

Discher, Dennis E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 

Dixon, Tracy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261 

Dodge, James C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201 

Doering, Christopher B.. . . . . . . . . . . . . . . . . . . . . . 189, 592, 826, 873 


158 


Doglioni, Claudio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 610 

Doillon, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 

Dolinsek, Tanja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 540 

Dollet, Sandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 706 

Donate, Amy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 711 

Dondero, R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896 

Dong, Lu-Jia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859 

Donnelley, Martin W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278 

Donnelly, Eleanor M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651, 907 

Donsante, Anthony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 747 

Doritchamou, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Doronin, Konstantin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4 

Dotti, Gianpietro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27, 496, 785 

Doubrovina, Ekaterina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230 

Dow, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 

Dowey, Sarah N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345 

Downey, Harre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 708 

Doyon, Yannick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Drescher, Charles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 815 

Dreyfus, Patrick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Drezek, Rebekah A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779 

Driessen, Gertjan J. A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Dronadula, Nagadhara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 732 

Dropulic, Boro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 592 

Drouin, Mathieu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5 

Du, Liang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 732, 739 

Du, Liutao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 

Duan, Dongsheng. . . . . . . . . . . . . . . . . . . . . . . . . . . 309, 481, 688, 771 

Dubensky, T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Dubreil, Laurence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 

Duffy, Margaret R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6 

Dufour, Brett D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 650 

DuFresne, Elizabeth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664 

Dumont, Nellie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5 

Dunbar, Cynthia E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113, 310 

Duncker, Dirk-Jan D. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713 

Durfee, Heather . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773 

During, Matthew J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 624 

Duros, Caroline. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 383, 389 

Durymanov, Mikhail O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Duvall, Craig L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 839, 841 

Duzgunes, Nejat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151 

E 

Eaves, Allen C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 860 

Ebert, Oliver. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793 

Egan, James. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626 

Egan, Josephine M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Ehrhardt, Anja. . . . . . . . . . . . . . . . . . . . . .139, 299, 378, 413, 630, 679 

Eipel, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411 

Eisterer, W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Ekblad, Maria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 807 

Ekstrom, Marta H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 704 

El-Amouri, Salim S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 306 

Elashoff, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142 

Elazar, Menashe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487 

Elgstrand Wettergren, Erika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879 

Eliav, Uzi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320 

Ellis, Brian L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 634 

Ellis, Collin L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286 

Ellis, Scott . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

Elmallah, Mai K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 

Elsabahy, Mahmoud. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 182 

Ely, Abdullah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 563 

Emborg, Marina E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670 

Emery, David W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33, 251 

Emmerechts, Jan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737 

Endo, Ayumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 723 

Endo-Takahashi, Yoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483 

Engelhardt, John F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .270, 275, 660 

Engelhardt, Sarah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 

Engler, Tatjana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .57, 416 

Enk, Alexander H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 

Enkirch, Theresa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110 

Ennis, Jane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212 

Enoki, Tatsuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 397, 407 

Enriquez de Salamanca, Rafael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Enssle, Joerg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865 

Epp, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366 

Epperly, Michael W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261 

Era, Takumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577 

Erbacher, Patrick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 638 

Erger, Kirsten E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104, 199 

Erika, Schmidt. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 

Ernstberger, Aaron . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111, 590 

Ertl, Hildegund C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680 

Escutenaire, Sophie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 795 

Esfandiarifard, Saghi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774 

Eshhar, Zelig . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 

Esko, Jeffrey D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142 

Esposito, Irene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793 

Esteban, Mariano. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 916 

Estrada-V, Erendira . . . . . . . . . . . . . . . . . . . . . 886, 887, 894, 895, 920 

Eto, Yoshikatsu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714, 721 

Eubanks, Lisa M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652 

Evangelio, Costanza . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Evans, Claire F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Ewert, Kai K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171 

Excoffon, Katherine J. D. A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7, 654 

Eymard, Bruno . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 


F 

Fae, Kellen C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 

Fagone, Paolo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379, 587 

Fahrendorff, Melanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 594 

Fairy, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 860


Fakhfakh, Raouia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471 

Fakhrai, Habib. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 814 

Falahati, Rustom. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 

Falcione, Antonella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 728 

Falcone, Laura. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 785 

Falk, Darin J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104, 901 

Falkenhagen, Alexander . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 897 

Fan, Shasha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 

Fan, Xia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 919 

Fan, Yufei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639 

Fang, Cheng-Chieh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 

Fargnoli, Anthony S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725 

Faria, Ana Paula P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 570 

Farinelli, Giada. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267 

Farley, Raymond. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165, 272 

Farr, MaryJane. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Farrokhi, Catherine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509, 784 

Farrow, Nigel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281 

Farruggio, Alfonso P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368 

Fassas, Athanasios. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Fattah, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729 

Faust, Susan M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291 

Federici, Thais . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651 

Federoff, Howard J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39, 755 

Federspiel, Mark J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23, 364, 802, 888 

Fehlings, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544 

Fehse, Boris . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572, 641 

Fender, Pascal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2, 18, 135 

Fenelon, Gilles. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Feng, Junli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366 

Feng, Yun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 244 

Fernandez, Stephanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 932 

Ferrari, Giuliana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298 

Ferraro, Bernadette. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504 

Ferreira, Nádia R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851 

Ferrige, Georgina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

Ferro, Leda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 

Ferrua, Francesca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Ferry, Nicolas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124 

Fewell, Jason G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Fidler, Jonathan A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201 

Fieger, Philipp . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 

Fielding, Adele K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 

Filali, Ebtisam E. l. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 858 

Finegold, Milton. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3, 45, 48, 277 

Finn, Eric E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .36, 472 

Finn, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .76, 466 

Finocchi, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267, 604 

Fioravanti, Jessica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776 

Fire, Andrew Z. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 424 

Fischbeck, Kenneth H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 882 

Fischer, Alain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 

Fishbein, Ilia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 733, 738 

Fisher, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270 

Fisher, Paul B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242 

Fisk, Nicholas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 

Fitch, Sally. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463 

Flake, Alan W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 823 

Flanigan, Kevin M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768 

Flannery, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872 

Flatt, Justin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4 

Flebbe-Rehwaldt, Linda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 

Fleming, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 

Flinders, Colin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423 

Flotte, Terence R. . . . . . . . . . . . . . . . 47, 341, 400, 404, 555, 649, 827 

Flournoy, Camille A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870 

Flynn Gilmer, Heather . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 775 

Flynn, Rowan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 

Foldvari, Marianna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 182 

Fong, Mei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 

Fong, Yuman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640, 678 

Fons, Michael P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 701 

Fontana, Melissa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 545 

Fontanellas, Antonio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Fontes, Andrew D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144 

Forbes, Scott P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 738 

Forde, Patrick F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 511, 196 

Forman, Stephen J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38, 89, 351, 352 

Forsayeth, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39, 647, 746 

Fortinberry, Henry K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 

Foster, Aaron E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .84, 779 

Foti, Stacey. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651, 871 

Foulad, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 787, 788 

Foust, Kevin D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392 

Foust, Kevin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647 

Fraldi, Alessandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401, 722 

Francis, Kevin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535 

Franco, Judith . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 

Francoise, Antoine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Frecha, Cecilia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876, 893 

Frederick, Amy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Frenk, Esther Z. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652 

Frenzke, Marie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .514, 515, 517 

Friedline, Randall . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555 

Friedman, Geoffrey. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 632 

Friedman, Robin C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561 

Frisch, Benoit. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180 

Frisch, Frederique . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 

Frisk, Per . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229 

Fromes, Yves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 

Frondorf, Kathleen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7 

Fronza, Raffaele . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264 

Fruehauf, Stefan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Fu, Ailing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 

Fu, Freddie H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758, 769 

Fu, Haiqing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302 


160 


Fu, Haiyan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337 

Fuentes de Albin, Martha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427 

Fujii, Tsutomu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Fujisawa, Masato . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Fujiwara, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777 

Fujiwara, Toshiyoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797, 800 

Fukuda, Takahiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 721 

Fukuhara, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796 

Fukunaga, Yoshitaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451, 456 

Fuller, David D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 

Fürst, Katharina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411 

Fury, Brian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 

Fusaki, Noemi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577 

G 

Gabellini, Davide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 757 

Gabriel, Nishanth. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121 

Gabriel, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 632 

Gaensler, Karin M. L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 

Gagné, Claude . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 

Gagnon, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381 

Gahan, Cormac G. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535 

Gahl, William A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457 

Galanis, Evanthia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23, 31, 365, 891 

Galetto, Roman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425, 576 

Galivo, Feorillo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .371, 574, 780 

Gallina, Pierangela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 610 

Galy, Anne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293, 589 

Gan, Chih Hao V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Gangeswaran, Rathi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516, 529 

Gao, Dongling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516 

Gao, Fei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Gao, Guangping. . . . . . . . . . . . . . . . . . . .400, 404, 555, 621, 649, 827 

Gao, Xueqin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373 

Gao, Yangjun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 321 

Garcia, Aida . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 431 

Garcia, Luis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72, 661, 831 

Garcia-Bañuelos, Jesus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420 

Gardner, Agnes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 586 

Gardner, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 

Gargiulo, Annagiusi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .401, 542, 722 

Garwick-Coppens, Sara E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .75, 467 

Gasiorowski, Joshua Z.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 691 

Gasmi, Mehdi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589 

Gatti, Richard A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 

Gattinoni, Luca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350 

Gaudet, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 

Gaussin, Armelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 383 

Gautney, Richard E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 592 

Gazit, Dan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 370, 761, 772, 856 

Gazit, Zulma . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 370, 761, 772, 856 

Gebremedhin, Senait. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151 

Gee, Adrian P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 

Gee, Adrian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496 

Gee, Samantha W. Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Geguchadze, Ramaz. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 465 

Gehl, Julie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447 

Gennery, Andrew R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 

Genovese, Pietro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .498, 631, 632 

Gentner, Bernhard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .94, 267 

Gerken, Claudia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .496, 781, 913 

Gersbach, Charles A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422 

Gerseny, Helen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675 

Gerson, Stanton L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 

Gesinger, Jonathan M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368 

Gessner, Debra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Gewen, Tan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 526 

Ghazi, Alexia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 

Ghazizadeh, Soosan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 376 

Ghio, Domenico. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605 

Gholami, Sepideh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678 

Ghoshal, Kalpana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

Giacca, Mauro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .532, 614, 728 

Giachelli, Cecilia M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 426, 741 

Giangrande, Paloma H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743, 834 

Giannelli, Stefania . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Gianni, Davide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 546 

Giannoni, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355, 786 

Giedlin, Martin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544 

Giedlin, Marty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598 

Giesen, Melanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 857 

Giffear, Mary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

Gijsbers, Rik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486 

Gilbert, Marie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 703 

Gilbert, Rénald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143, 381 

Gill, Deborah R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884 

Gillespie, George Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 

Giordano, Frank A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Giorgio, Todd D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 839 

Girard, Mathilde . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 706 

Giustacchini, Alice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94 

Gjata, Bernard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Glader, B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Glascock, Jacqueline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 455 

Glazer, Peter M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 

Glenn, Jeffrey S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487 

Glimm, H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 

Glimm, Hanno . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223, 269, 343, 632 

Glorioso, Joseph C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53, 56 

Glushakova, Lyudmyla G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Gnidehou, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Godbout, Jonathan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362 

Godwin, Simon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Goetzmann, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400 

Goez, Anneliese . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 804 

Goh, Eyleen Lay Keow . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844 



Goldowitz, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Gonen, Mithat. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Gonzaga, Bruno C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 570 

Gonzalez, Lorena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Goodman, Alan G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 916 

Goodrich, LR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871 

Gorbatyuk, Marina S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204 

Gordts, Stephanie C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737 

Gothelf, Anita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447 

Gottenberg, Jacques-Eric. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Gottfried, Lynn F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149 

Gottschalk, Stephen M.. . . . . . . . . . . . . .27, 220, 357, 496, 781, 913 

Gouble, Agnès . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425, 576 

Goudy, Kevin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .287, 290, 377 

Gould, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238 

Govindasamy, Lakshmanan. . . . . . . . . . . . . . . . . . 330, 332, 402, 405 

Gracey, Lia E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 424 

Grada, Zakaria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 

Grandi, Paola . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 

Grant, Rebecca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19, 186, 196 

Gräslund, Torbjörn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879 

Graves, Edward E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 541 

Graves, Scott S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623 

Gray, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Gray, John T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .259, 379, 587 

Gray, Steven S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651 

Gredler, Rachel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242 

Green, Karin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341 

Green, Victoria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208 

Greenberg, Barry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601 

Greenberg, Philip D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498 

Greenberger, Joel S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261 

Greene, Mike. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379 

Greenslade, Andrew. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364 

Greentree, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 

Greer, Brian B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 771 

Gregory, Philip D.. . . . . . . . . . . . . . . . . . 26, 49, 93, 99, 268, 314, 423, 

. . . . . . . . . . . . . . . . . . . . . 484, 498, 598, 631, 632, 633, 648, 689, 903 

Greig, Jenny A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 874 

Greiner, Dale L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 

Greiner, Suzanne M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364 

Grez, Manuel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267, 269, 347, 348 

Grieger, Josh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651 

Grieger, Joshua C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585 

Griesenbach, Uta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .108, 165, 272 

Grieves, Jessica L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617 

Griffiths, Duncan A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 595 

Grilley, Bambi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 

Grimm, Dirk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127, 394 

Grimstein, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669 

Gritti, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 631 

Grompe, Markus . . . . . . . . . . . . . . . . . . . . . . . . .48, 187, 371, 463, 574 

Gross, Alecia K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Gross, David-Alexandre. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Grossardt, Christian. . . . . . . . . . . . . . . . . . . . . . . . . . 514, 521, 528, 798 

Grossman, Robert G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 781 

Groth, Amy C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 

Grove, Nathan C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147, 414 

Grove, Nathan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3, 45, 277, 419 

Grover, Rajat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615 

Gruenert, Dieter C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Grunseich, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 882 

Grünwald, V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82 

Gu, Feng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 636 

Gu, Yixue. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 

Guelcher, Scott A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 841 

Güenechea, Guillermo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Guenther, Margaretha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 

Guenzel, Adam J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 658 

Guerlevik, Engin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790, 804 

Guerra, Susana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 916 

Guh, Jinn-Yuh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Gui, Tong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832 

Guilbault, Claire . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381 

Gul, Hilal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318 

Guntani, Atsushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Günzburg, Walter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Guo, Changsheng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463 

Guo, Fengjin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758, 769 

Guo, Siqi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 708, 711 

Gupta, Mukesh K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 841 

Gurda, Brittney L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .332, 333, 374 

Gurruchaga, Jean-Marc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Guse, Kilian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .54, 478 

Gussing, Fredrik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879 

Guttridge, Denis C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96 

Guy, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 

H 

Haase, Rudolf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 413 

Haavisto, Elina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 795 

Haber, Tom. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 582 

Habib, Nagy A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559 

Habli, Mounira . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 

Hacein-Bey-Abina, Salima . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41, 42 

Hacke, Katrin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Hackett, Neil R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .195, 200, 652 

Hackett, Perry B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 

Hadaczek, Piotr. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 

Haddad, Dana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640, 678 

Haddad, Daniel J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Haddad, Hafedh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Hagedorn, Claudia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390 

Haggerty, Carolyn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729 

Haghighi, Ali . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 814 

Hajjar, Roger J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668 


162 


Hajjar, Roger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601 

Hakim, Chady H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 771 

Hakin, Chady H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309 

Hakkarainen, Tanja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295 

Halbert, Christine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 

Hall, Christine A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 550 

Hall, Lindsay J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 511 

Halldén, Gunnel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 801, 807 

Hamada, Katsuyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237, 418 

Hamakawa, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 418 

Han, Joohee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .58, 525 

Han, KuyLee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833 

Han, Myung-Shin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308 

Han, Sang W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742 

Han, Sang Won. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 446 

Han, Yu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 915 

Handy, Chalonda R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651, 907 

Hanenberg, Helmut . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 

Hannah, William. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832 

Hannaman, Drew W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Hantraye, Philippe. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Hao, Ergeng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 868 

Hapke, G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Harada, Yui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523, 813 

Harada-Shiba, Mariko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .61, 181 

Harashima, Hideyoshi . . . . . . . . . . . . . . . . . . . . . . . 433, 444, 709, 835 

Harbottle, Richard P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 751 

Hardcastle, Jayson. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362 

Hardee, Cinnamon L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 786 

Hardee, Cinnamon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 

Hardenberg, Gijs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334 

Harding-Smith, Rebekka E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884 

Hareendran, Sangeetha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121 

Harel, Asaff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53 

Hargrove, Phillip W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 262 

Harjeet, Singh S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 234 

Harms, Nina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 630 

Harper, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759 

Harper, Scott Q. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .75, 467 

Harrington, Kevin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361 

Harris, Dawn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

Harris, Kyle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 592 

Harrison, Frank . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 712 

Hart, Stephen L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156 

Hart, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 

Hartline, Cassie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353 

Hasegawa, Mamoru . . . . . . . . . . . . . . . .103, 190, 222, 233, 523, 577 

Hashida, Mitsuru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .319, 430, 443 

Hashimoto, Yuuri . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797, 800 

Haskins, Mark E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43, 719, 726 

Hatano, Koji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 

Hauck, Bernd. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 403 

Haugwitz, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 

Haurigot, Virginia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Hauschka, Stephen D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .36, 466 

Hauser, Michael A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 467 

Haushalter, Karl A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489 

Häusl, Martin A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 

Hausl, Martin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .378, 413, 679 

Hauswirth, William W. . . . . . . . . . . . . . . . . . . . . . . . 199, 203, 204, 648 

Havranek, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 

Hawkins, Troy B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111 

Hawkins, Troy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 590 

Hay, John G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 415 

Hayashi, Yasuhiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .433, 709, 835 

Hayashita-Kinoh, Hiromi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 764 

Hayes, Daniel J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 

Hayes, Teresa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496 

He, Dongmei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 321 

He, Ran . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400, 404, 555, 649, 827 

He, Xianghui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 792, 866 

He, Yukai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213 

He, Zhihai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 771 

He, Zhimin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 

Hean, Justin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 563 

Hebbel, Robert P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 822 

Hebel, Henry L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 597 

Hegde, Meenakshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27, 913 

Hege, Kristen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Heinen, Paul P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 916 

Heldermon, Coy D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 717 

Heller, Loree. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 711 

Heller, Richard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .441, 708, 711 

Hellerbrand, Claus. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793 

Hemminki, Akseli. . . . . . . . . . . . . . . . . . . . 2, 18, 55, 77, 295, 478, 795 

Henley, Jill E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314 

Henschler, Reinhard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 857 

Hensel, Jonathan A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615 

Hentati, Fayçal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Herberman, Ronald B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899 

Herdewijn, Piet. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 563 

Herijgers, Paul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737 

Herman, Andy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 

Hermiston, Michelle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Hernandez, Jessica A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 

Herschman, Harvey R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142 

Herson, Serge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Hervas-Stubbs, Sandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Herzog, Erik D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 717 

Herzog, Roland W.. . . . . . . . . . . . . . . . . .288, 296, 402, 619, 663, 825 

Heslop, Helen E. . . . . . . . . . . . . . . . . . . . . . . . . . . .20, 27, 496, 591, 913 

Hiatt, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277 

Hice, Robert H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 

Hickey, Raymond D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371 

Hickey, Raymond. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574 

Hicks, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496 



Hicks, Martin L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .170, 283, 652 

Hickstein, Dennis D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .258, 346, 613 

Higgs, Jerome T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615 

High, Katherine A. . . . . . . . . . . . . . . . . . . . . . . . .49, 403, 600, 602, 823 

Higuchi, Yuriko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319 

Hikichi, Mina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359 

Hildebrandt, B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Hillestad, Matthew L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 658 

Hirabayashi, Yuka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315 

Hirai, Yukihiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 

Hiralall, Johan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 858 

Hiraoka, Kei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535, 869 

Hirata, Roli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10, 636 

Hiroshima, Kenzo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Hirsch, Matthew L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620, 634 

Hitt, Mary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 808 

Ho, On . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485 

Ho, Weng Hang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859 

Hoare, Mike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 450 

Hodgson, Clague P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694 

Hoeben, Rob C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Hofer, Ursula . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .99, 314 

Hoffman, Brad E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296 

Hogrel, Jean-Yves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51, 72 

Hole, Patrick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 595 

Holley, Rebecca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336 

Hollis, Roger P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423 

Hollis, Roger. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 

Holmes, Michael C. . . . . . . . . . . . . . . . . . . . . . 26, 49, 93, 99, 268, 314, 

. . . . . . . . . . . . . . . . . . . . . 423, 484, 498, 598, 631, 632, 633, 689, 903 

Holt, Nathalia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314 

Holt, Robert A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Holzbaur, Erika L. F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618 

Homma, Yukio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796 

Hong, Seong-Ho . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909 

Hong, Yuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213 

Hoogaars, Willem M. H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765 

Hoogstraten-Miller, Shelley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457 

Horton, Lois . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Hosoyama, Sachiko Ohshima. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473 

Hossain, Fokhrul M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Hou, Jiangang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796 

Hou, Wei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412 

Howard, Lynsey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727, 853 

Howe, Ruth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 718 

Howe, Simon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336 

Howe, Steven J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Howell, Craig A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834 

Howes, Rob . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908 

Hoylaerts, Marc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737 

Hoyler, Birgit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110 

Hsieh, Matthew M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117, 385 

Hsieh, Ming-Kun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 927 

Hsu, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .550, 579, 864 

Hsu, Jen-I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178 

Hsu, Shu-hao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

Hsu, Yi-ling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866 

Hu, Chuhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285 

Hu, Hailiang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 

Hu, Shiu-Lok . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485 

Hu, Youjin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697 

Hu, Yu-Chen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 

Hu, Zebin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675 

Huang, Baocheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 

Huang, Jenny . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436 

Huang, Jeremiah W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 907 

Huang, Li T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 376 

Huang, Liang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302 

Huang, Li-Min . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 

Huang, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Huang, Qian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 756 

Huang, Shu Hung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 322 

Huang, Wenlin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Huang, Xueyin N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 659 

Huang, Ya-Hui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 

Huard, Johnny . . . . . . . . . . . . . . . . . . . . . . . . . . .96, 367, 373, 758, 769 

Huard, Mathieu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373 

Hubbard, Brian K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Hudacek, Andrew W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515 

Hui, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 

Huizing, Marjan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457 

Hul, Helen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353 

Huls, Helen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 224, 225, 500 

Hung, Jui-Hung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555 

Hung, Min-Yuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Hung, Shih-Chieh . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 325, 862, 924 

Hung, Tsung-Jen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Hunter, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 346 

Hunter, Michelle R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 501 

Huppert, Volker . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 594 

Hurbult, Gregory D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201 

Hurtado, Daniela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405 

Hurton, Lenka V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354 

Hurwitz, Mary Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 

Hurwitz, Richard L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 

Huseinovic, Angelina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 569 

Huston, Marshall W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 252 

Huyn, Steven. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145 

Huynh, Cong Truc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166 

Huynh, Dai Phu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166 

Hwang, Jae Youn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 843 

Hwang, Ki-Chul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 740 

Hwang, Mark E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 

Hwang, Misako. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194, 646 

Hwang, Tae-Ho. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 


164 


Hwu, Wuh-Liang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 458, 724 

Hyde, Stephen C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 884 

Hyland, Kendra A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 255 

Hyodo, Mamoru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709 

I 

Iankov, Ianko D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23, 365 

Iannitti, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3 

Ichikawa, Tomohiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 813 

Ichwan, Brian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 310 

Icyuz, Mert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 

Ida, Hiroyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714, 721 

Igarashi, Tsutomu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 754 

Ihn, Hironobu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577 

Iida, Akihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577 

Iida, Hidehiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 581 

Ikarashi, Yoshinori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235 

Ikawa, Masahito . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Ikawa, Yasuhiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 

Ikeda, Hiroaki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777 

Ikeda, Yasuhiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311 

Ikeda, Yutaka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305 

Ikramy, Khalil A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433, 835 

Ildefonso, Cristhian J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 

Ilett, Elizabeth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 780 

Imamura, Michio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 

Imbrogno, Kara. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 769 

Imbrogno, Kayla. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 367 

Inagaki, Akihito. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535, 869 

Ingle, Nilesh P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 

Ino, Yasushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796 

Inoguchi, Hiroyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Inoue, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 222, 233, 861 

Inoue, Makoto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 190, 222, 233 

Inoue, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .97, 233 

Ippodrino, Rudy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 614 

Ironside, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257, 344 

Isaev, Dmitry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 

Isaksson, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301 

Isgrò, Antonella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267 

Ishida, Eri. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248 

Ishige, Nobuyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714 

Ishii, Takehiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 

Ishii, Yuko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483 

Ishikawa, Kiyotake . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668 

Ishiwata, Akira. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188 

Itaka, Keiji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 

Itkin-Ansari, Pamela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 868 

Ito, Kensaku . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523 

Ito, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .152, 154, 237 

Itoh, Hiroyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Ivanovska, Irena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 

Ivics, Zoltan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 

Iwamoto, Takeo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 721 

Iwanaga, Yuzuru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315 

Izsvak, Zsuzsanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 

Izuka, Sayoko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 721 


J 

Jackson, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .90, 740 

Jackson, George W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353 

Jackson, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Jacob, Danielle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381 

Jacob, Samson T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

Jacobi, Ashley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271 

Jacobs, Frank. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737 

Jacques, Sebastien . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Jaenisch, Rudolf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 

Jahn, Stephan C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 619 

Jamali, Layli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Jamison, R. Aidan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278 

Jan, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Janda, Kim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .170, 283, 652 

Jang, Jae-Hyung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122 

Jang, Yeon Lim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166, 817 

Janke, Laura J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259 

Jansen, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 566, 569 

Jansson, Volkmar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 767 

Janus, Jeffrey. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 854 

Jares, Alexander . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 

Jarjour, Jordan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .35, 687 

Jarraya, Bechir. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Jasti, Aparna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .111, 112, 590 

Jay, Chris M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457 

Jayandharan, Giridhara R.. . . . . . . . . . . . . . . . . . . . . . . . .121, 131, 619 

Jean, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 881 

Jensen, Michael C.. . . . . . . . . . . . . . . . . . . . . . . .38, 351, 352, 499, 501 

Jensen, Thomas G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 760 

Jeong, Chang Hyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580 

Jeong, Hwa Yeon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158 

Jeong, Ji Hoon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .166, 734, 817 

Jeong, Wha Yeon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160 

Jessup, Mariell. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601 

Jeun, Sin-Soo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580 

Jiang, Bo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 739 

Jiang, Guozhong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529 

Jiang, Hao-Yuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 327 

Jiang, Hu-Lin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909, 926 

Jiang, Ming-Ming . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 

Jin, Hee Kyung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 918 

Jin, Qingwen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 

Jin, Seori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 707 

Jin, Sheng-Yu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193


Jo, Dong-Gyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817 

Joensuu, Timo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .77, 795 

Joglekar, Alok V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423 

Johana, Nuryanti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 

Johnsen, Angela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Johnson, Aime K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194, 646 

Johnson, Gary M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 596 

Johnson, Jacob A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646 

Johnson, Russell N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65, 174, 177 

Johnston, Ian C. D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 594 

Johnston, Jennifer M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 826 

Johnston, Jennifer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189 

Jolly, Douglas J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Jones, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340 

Jones, Haven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 621 

Jones, Heather . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599 

Jones, Helen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 

Jones, Jeffrey A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261 

Jones, Rachel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153 

Jones, Simon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336, 716 

Jones, Steven J. M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Jones, Victoria J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194, 646 

Jonnalagadda, Mahesh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 352 

Joo, Kye-Il . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132, 387 

Josephson, Neil C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366 

Joshi, Bharat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 

Joshi, Sadhna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 897 

Joubert, Vanessa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 703 

Joung, J. Keith. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300, 686 

Judd, Justin H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 408 

Judge, Eoin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626 

June, Carl H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 782 

June, Carl . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Jung, Daniel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5 

Jung, Hye S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Jung, Keun-Hwa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880 

Jung, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 

Jung, Ulrike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 

Junghans, Richard P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 

K 

Kabanov, Alexander V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 922 

Kacherovsky, Nataly A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 426 

Kadner, Karen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629 

Kaeppel, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 

Kaeppel, Christine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .46, 632 

Kafri, Tal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832 

Kagawa, Shunsuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 800 

Kaja, Aparna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13, 15 

Kajimoto, Kazuaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 835 

Kakarla, Sunitha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357, 781 

Kakkis, Emil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774 

Kaler, Stephen G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 747 

Kalies, Katrin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506 

Kallai, Ilan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 370, 761, 772 

Kaluza, Karen K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 358 

Kaluza, Karen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 775 

Kamat, Rohan H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 388 

Kamata, Wakako. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181 

Kamen, Amine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381 

Kamijima, Shuichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Kamimura, Kenya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 627, 705 

Kaminsky, Stephen M. . . . . . . . . . . . . . . . . . . 170, 283, 652, 653, 821 

Kane, Nicole M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727, 853 

Kaneda, Yasufumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227, 736 

Kanefuji, Tsutomu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444, 627 

Kanegae, Kazuko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190 

Kanerva, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77, 295, 795 

Kang, Eunah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 685 

Kang, Jeong-hun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181 

Kang, Leong-Hun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150 

Kangasniemi, Lotta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .77, 795 

Kanzaki, Akiyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Kao, Chun-Yu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 

Kao, Yi-Hsuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 924 

Kapoor, Neena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 

Karali, Marianthi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542, 665 

Karan, Sukanya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199 

Karapetyan, Gevorg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320 

Kardos, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 701 

Karimi-Busheri, Feridoun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 814 

Karlsson, Hannah. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229 

Karow, Marisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368 

Kasahara, Noriyuki. . . . . . . . . . . . . . . . . . . . . . . .95, 524, 535, 559, 869 

Kasahara, Yuko Nitahara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473 

Kashiwakura, Yuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190 

Kaspar, Brian K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392 

Kaspar, Brian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647 

Kaspar, Roger L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427 

Kasper, Brian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768 

Kassim, Sadik H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 

Kastberger, Birgit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 

Kasuya, Hideki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Katakai, Yuko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 

Kataoka, Kazunori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 

Katari, Usha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503 

Katayama, Kazufumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 682 

Katayama, Yoshiki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150, 172 

Katebian, Behrod. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 

Katz, Martin L . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870 

Katz, Michael G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725 

Kaufmann, Johanna K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 528 

Kaufmann, Kerstin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348 

Kaufmann, Stefan H. E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 

Kaul, Sunil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527 

Kaur, Balveen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362 


166 


Kaur, Kamaljit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 

Kauss, M. Ariel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329 

Kavanagh, Heather . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626 

Kawabata, Kenji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 682 

Kawaguchi, Yoshifumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 

Kawakami, Shigeru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .319, 430, 443 

Kawamura, Kiyoko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Kawano, Hirotaka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 861, 925 

Kay, Mark A. . . . . . . . . . . . . . . . . . . . . . 11, 86, 148, 331, 424, 487, 602 

Kayali, Refik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .71, 470 

Kaza, Niroop . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615 

Kean, Thomas J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 855 

Keeler, Allison M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341 

Keilman, George W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623 

Keirnan, Jacqueline. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 503 

Keiser, Megan K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198 

Keiser, Nicholas W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270, 660 

Kellar, Denise L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 500 

Kellar, Denise. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 

Kelleher, Michelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

Kells, Adrain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 647 

Kells, Adrian P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 206, 746 

Kelson, Kyle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509, 784 

Kemaladewi, Dwi U. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765 

Kemmerrer, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 701 

Kemnade, Jan O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783 

Kempuraj, Duraisamy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655 

Kendra, K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891 

Kennedy, Laura C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779 

Kent, Oliver A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 892 

Keramaris, Elizabeth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 766 

Keramaris-Vrantsis, Elizabeth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468 

Kerami, Mariam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303, 307 

Kernan, Nancy A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230 

Kerns, Hannah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349 

Keswani, Rahul K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 

Keswani, Sundeep. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 

Kew, Yvonne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 781 

Khai, Nign Cin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898 

Khan, Amir S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22, 504 

Khan, Iram F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384, 474 

Khan, Rafat. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Khanin, Raya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727 

Khare, Reeti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8, 60, 414 

Khayter, Cyd. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300 

Khazi, Fayaz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .49, 883 

Khim, Socheath . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260 

Kho, Jordan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384, 474 

Khokher, Zeshan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774 

Khoury, Maroun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 

Khramtsov, Yuri V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Khundkar, Tahsin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 752 

Kidokoro, Minoru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359 

Kiem, Hans-Peter . . . . . . . . . . . . . . . . . . . . . . .191, 226, 251, 257, 342, 

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 344, 372, 485, 637, 865 

Kienle, Eike. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394 

Killedar, Smruti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337 

Kim, Baek . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 676 

Kim, Dal-Soo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580 

Kim, Dong-Eun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297, 435 

Kim, Dongho. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818 

Kim, Dukmi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 917 

Kim, Eunji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 543 

Kim, Hakkyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 

Kim, Hyun Ah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279, 549 

Kim, Jaerim. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 685 

Kim, Jaesung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527, 806 

Kim, Ji-Eun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909, 929 

Kim, Jin-Soo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 543 

Kim, Jit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 687 

Kim, Jocelyn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219 

Kim, Joo-Hang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818 

Kim, Jsaon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555 

Kim, Jung Seok. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160 

Kim, Jung Seol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158 

Kim, Kenneth. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99 

Kim, Keun-Sik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158, 160, 297, 435 

Kim, Kyung-Bo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297 

Kim, Mi K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Kim, Minjung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145, 421 

Kim, Myung Goo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166, 817 

Kim, Nahyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 740 

Kim, Pyung-Hwan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145, 806 

Kim, Seho . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435 

Kim, Seong Muk. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580 

Kim, So Y.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818 

Kim, Soya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Kim, Sun Hwa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166, 734 

Kim, Sung Wan . . . . . . . . . . . . . . . . . . . . . . . . . 159, 161, 560, 685, 806 

Kim, Tae K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Kim, Tae-Il . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560, 806 

Kim, Yong-Oock . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140 

Kim, Yoon-Sang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 262 

Kim, You-Kyoung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909, 926 

Kimelman-Bleich, Nadav . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 772 

Kimpel, Janine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486 

Kimura, En . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Kimura, Tsuyoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434 

King, Gwendalyn D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787 

Kingsman, Susan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Kingston, H. M. Skip . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 465 

Kinnon, Christine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Kinoh, Hiroaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523 

Kinoh, Hiromi Hayashita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473 

Kirk, Kaitlyn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 868 

Kirn, David H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .50, 599 



Kirsten, R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 

Kishida, Akio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434 

Kiss, Szilard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 653 

Kitagawa, Teruyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714 

Kitahara, Masahiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248 

Kitamura, Atsushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282 

Klatzmann, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Klausner, Eytan A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 751 

Kleff, Veronika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Klein, Christoph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Klimash, June . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644 

Klimczak, R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872 

Klopp, Ann . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533 

Klüppel, Luciana M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851 

Kneissl, Sabrina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110, 830 

Knocke, Sarah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790 

Knoepfler, Paul S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 575 

Knop, David R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 593 

Knowling, Stuart E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 554 

Knuteen, Russell. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 718 

Knutson, Darlene. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 775 

Ko, Kyung S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Kobayashi, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 714, 721, 805 

Kobinger, Gary P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212, 216 

Kobinger, Gary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 429 

Kobner, Scott. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 

Kocak, Ergun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 624 

Koch, Walter J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725 

Kochanek, Stefan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .57, 416 

Kochetkova, Olga . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 854 

Köchling, Joachim. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506, 507 

Koeberl, Dwight D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338, 339 

Koeberl, Dwight. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289 

Koeberle, Paulo D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544 

Koefoed, Mette J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 760 

Kogan, Scott . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Kohlbrenner, Erik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668 

Kohn, Donald B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355, 423, 712, 786 

Koilkonda, Rajeshwari D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 

Koirala, Adarsha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 748 

Koldej, Rachel M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256 

Kondratenko, Irina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Kong, Derek. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Kong, Seogkyoung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 

Koniar, Brenda L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 

Konieczny, Patryk. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 475 

Konno, Shunichi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 

Konopka, Krystyna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151 

Konstantinova, Pavlina . . . . . . . . . . . . . . . . . 562, 564, 566, 569, 847 

Koob, George . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 283, 652 

Koons, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151 

Koornneef, Annemart . . . . . . . . . . . . . . . . . . . . . . . 562, 564, 569, 847 

Kordower, Jeffrey. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870 

Koriyama, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736 

Korman, V. L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 

Korman, V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 836 

Kornegay, Joe N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 

Korsgren, Olle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 502 

Kosai, Ken-ichiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898 

Koski, Anniina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .77, 795 

Kota, Janaiah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867, 892 

Kotin, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 661 

Kottke, Timothy J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .358, 361, 780 

Koyama, Yoshiyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152, 237 

Kranjc, Simona . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448, 540 

Kranz, David M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356 

Krause, Anja. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 210, 490 

Kren, B. T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .67, 836 

Kren, Betsy T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427 

Kreppel, Florian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57, 147, 416 

Krishnamurthy, Sateesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271 

Kroeger, Kurt M. . . . . . . . . . . . . . . . . . . . . .59, 509, 784, 787, 788, 789 

Kron, Matthias W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 

Kroon, Evert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 868 

Krsmanovic, Mihajlo L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Ku, Jin-Mo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 

Kuan, Alex. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 

Kuball, Jurgen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498 

Kubicka, Stefan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790, 804 

Kubo, Shuji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 524, 805 

Kubodera, Takayuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 

Kucharski, Cezary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162 

Kudva, Yogish . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311 

Kuehnel, Florian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790, 804 

Kuftinec, Gabriela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423 

Kühlcke, Klaus. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Kuhn, Joseph. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Kuhr, Christian S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623 

Kumar, Padmasini . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Kumar, Priti. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .90, 740 

Kumar, Sanjay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 323 

Kume, Akihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188, 573, 696, 791 

Kung, Hsiang-fu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819 

Kuo, C-J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873 

Kupsch, Jörg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 528 

Kuroda, Masayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 

Kurosaki, Hiromasa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 539 

Kurosaki, Mariko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 539 

Kurupati, Raj K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680 

Kushmeric, Martin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 

Kutay, Huban. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

Kutschera, Ina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 

Kuwahara, Hiroya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .92, 553 

Kuzmenko, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390 

Kuzmickas, Ryan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300 

Kwon, Hyun-Mi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435 


168 


Kwon, Min J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Kwon, Oh-Joon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .145, 421, 685 

Kwon, Young Jik. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116, 164 

Kwong, Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678 

Kyuragi, Ryoichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

L 

l’Homme, Bruno. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 

La Perle, Krista. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

La Russa, Vincent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239 

Lacayo, Liliana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509, 784 

Lachmann, Nico. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .32, 369 

Ladage, Dennis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668 

Laforet, Pascal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Lagasse, Eric. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371, 574 

Lagisetty, Kiran H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231 

Lagresle, Chantal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Lahaye, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 

Lai, Chen Yi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312 

Lai, Chung Sheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 322 

Lai, Raymond . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 

Lai, Yi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309 

Lai, Yi-Hui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 522 

Lakshmipathy, Uma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144, 445 

Lalezari, Jay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598 

Lam, Viola C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Lamarre, Marven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 622 

Lamarre, Yann . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471 

Lamb, Lawrence S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 

Lampe, Johanna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515 

Landry, Breanne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .155, 534, 810 

Lang, Victoria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 857 

Langford-Smith, Alexander W. W. . . . . . . . . . . . . . . . . . . . . . 336, 716 

Langford-Smith, Kia J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336, 716 

Lankester, Arjen C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Laprise, Stéphanie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Lapteva, Natalia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 591, 783 

Lapus, Felycette G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 932 

Larcher, Fernando . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759 

Larochelle, Andre . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113, 310 

Larochelle, Nancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 

Larsen, John D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 914 

Laskey, Joseph A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Latella, Maria Carmela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 

Laufs, Stephanie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Laulund Christensen, Camilla. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 905 

Lauten, Melchior . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506, 507 

Lavasanifar, Afsaneh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 

Lavertu, Marc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .699, 881, 904 

Lavi, Amir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 761 

Lavigne, Marc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389 

Lavilla-Alonso, Sergio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 684 

Lavrencak, Jaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448 

Law, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3 

Lawrence, Roger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142 

Lawson, Gregory W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Le Blanc, Shannon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281 

Le Guiner, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .72, 124 

Le, Uyenchi N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 917 

LeBec, Christine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Leber, Mathias F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521, 798 

Leber, Mathias Felix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514 

Lech, Patrycja J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 538 

Lechman, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94 

Lee, Albert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Lee, Benhur . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609 

Lee, Brendan H. I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 

Lee, Brendan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 478, 820 

Lee, Chi-Lin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387 

Lee, Dean A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 240, 353, 508 

Lee, Donghoon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 

Lee, Doo Sung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166 

Lee, Eun K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285 

Lee, Gary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544, 598 

Lee, Gwang-Hyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435 

Lee, Hyung Joo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 543 

Lee, Jessica. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

Lee, Ki Jeong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 671 

Lee, Kun-Ze . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 

Lee, Lily . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 

Lee, Min Hyung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 549 

Lee, Min Sang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166, 817 

Lee, Minhyung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .279, 710, 734 

Lee, Ni-Chung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 458, 724 

Lee, Sang Ho . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Lee, Sang Kun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880 

Lee, Sang-Kyung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 740 

Lee, Seung-Koo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308 

Lee, Sharon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 

Lee, Soon H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Lee, Soon-Tae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880 

Lee, Soung-Kyung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421 

Lee, Tao-Chen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Lee, Won Jai. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140 

Lee, Woo Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 622 

Lee, Yeon Kyung. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158, 160 

Lee, Young Won . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159 

Lee, Yuhan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166 

Lee, Yu-May . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 458 

Leen, Ann M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20, 503, 513, 591 

Legakis, Giannoulis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272 

Léger, Adrien. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124 

Leger, Andrew J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Legorreta–Herrera, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 920 

Lei-Butters, Diana C. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270, 660 

Leif, Jean . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 




Lemaire, Frédéric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 576 

Lemay, Julie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390 

LeMeur, Guylène . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 

Lemoine, François M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Lemoine, Nicholas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 801, 807 

Lemoine, Nick R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516 

Lemoine, Nick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529 

Lemp, Nathan A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Leng, Qixin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 

Leo, Simone. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606 

Leonard, Vincent H. J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514 

Leopold, Philip L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153, 622 

Lepetit, Helene. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Leroy, Stanley G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194, 646 

Lesniak, Maciej S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 683, 915 

Leturcq, France. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Levine, Bruce. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Levings, Megan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334 

Levitt, Jon M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783 

Lévy, Camille . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 893 

Levy, Robert J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 733, 738 

Lewandrowski, Grant. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307 

Lewin, Alfred S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204, 901 

Li, Baozheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131 

Li, Chengjian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555 

Li, Chengwen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 620 

Li, Chengyao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .218, 391, 930 

Li, Dejia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309, 481 

Li, Dinggang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639 

Li, Dongling. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735 

Li, Haitang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 265 

Li, Hojun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Li, Hongmei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 839 

Li, Hongshuai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373 

Li, Hongwei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218, 391 

Li, Hui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102, 900 

Li, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Li, JianBin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 

Li, Jianbin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 766 

Li, Juan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .52, 468 

Li, Julia J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819 

Li, Li. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 

Li, Lijing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99, 314, 586 

Li, Liyuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 536 

Li, Mengxin . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400, 404, 555, 621, 827 

Li, Mingyuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 244 

Li, Senlin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202 

Li, Sheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 333, 770 

Li, Songtao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289, 339 

Li, Weidong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 792 

Li, Wen Chang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 805 

Li, Wenjuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 438 

Li, Wenzhong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677 

Li, Xiaopeng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399 

Li, Xiaozhu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516 

Li, Yan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216, 244 

Li, Yanhua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 919 

Li, Yi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120, 384 

Li, Zong-Yi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135 

Li, ZongYi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2, 18, 497, 578 

Liang, Desheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697, 698 

Liang, Huaping. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 919 

Liang, Keng-San. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171 

Liang, Yin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859 

Liao, Amy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910 

Liao, Jin-Lin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 927 

Liao, Jiyuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 861, 925 

Liao, Tung-Nan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Liberski, Alexandra M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153 

Libleau, Lise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 

Lieber, Andre. . . . . . . . .2, 18, 78, 135, 226, 497, 578, 689, 815, 852 

Liikanen, Ilkka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295, 795 

Lim, Foong-Yen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 

Limberis, Maria P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 108, 214, 326, 545 

Lin, Amy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Lin, Chi-Chen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 512, 584 

Lin, Chii Mei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 302 

Lin, Chin-Yu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 

Lin, Chung-Ren . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 547 

Lin, Clayton . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168 

Lin, Feng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 429 

Lin, Jacqueline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294 

Lin, Jianping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186, 340 

Lin, Kun-Ju . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 

Lin, Marie C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819 

Lin, Matt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219 

Lin, Sin Daw. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 322 

Lin, Xin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 

Lin, Xubin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Lindemann, Dirk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 

Linden, Rafael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 753 

Lindert, Steffen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4 

Lindqvist, Camilla . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229 

Lindstein, Tullia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291 

Linette, G . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891 

Ling, Changquan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Ling, Chen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131, 330, 402, 406 

Lins, Bridget. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 327 

Linton, Gilda F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833 

Liou, Amiee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 

Lipps, Hans-Joachim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390 

Lipshutz, Gerald S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285 

Lisowski, Leszek . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 331, 487 

Littman, Nick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 903 

Liu, Chao-Lien. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294 

Liu, Chunsheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 794

170 


Liu, Chunyan . . . . . . . . . . . . . . . . . . . . . . . .59, 509, 510, 784, 788, 789 

Liu, Dexi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .444, 627, 705 

Liu, Guo-Zheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Liu, Hao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496 

Liu, Jan-Jan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 316 

Liu, Jian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 467 

Liu, Katherine H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Liu, Li . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Liu, Mingdong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 

Liu, Paul Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773 

Liu, Pei-Qi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498 

Liu, Qing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .99, 586 

Liu, Shilian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537 

Liu, Su-Fen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Liu, Xiaolin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639 

Liu, Xiaoming . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270, 275 

Liu, Xiaoxuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 928 

Liu, Xionghao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697, 698 

Liu, Xiu Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834 

Liu, Xiuying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743 

Liu, Yanxin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537 

Liu, Yarong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132 

Liu, Ying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226, 628 

Liu, Yuli. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719, 726 

Liu, Z. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896 

Lloyd, Clare M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272 

Lo Riso, Pietro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93 

Lo, Hanson . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910 

Loader, Julie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

Lockey, Tim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379 

Loeb, Keith R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623 

Logg, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Lombardo, Angelo . . . . . . . . . . . . . . . . . . . . . . .93, 498, 631, 632, 633 

Lomeli-R, Christian Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 886, 887 

Lopez, Patricia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Lopez, Veronica M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238 

Loreto, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Loretz, Carol. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 

Lorson, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 455 

Loskog, Angelica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229 

Loskog, Angelika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 502 

Losordo, Douglas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Lotteau, Vincent. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 706 

Lou, Howard H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153, 622 

Louis, Sharon A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 860 

Louis-Jeune, Vedell . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668 

Lovelett, Emilie A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251 

Lovric, Jasmina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 614 

Lowe, Emily . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 

Lowenstein, Pedro R. . . . . . . . . . . . 59, 509, 510, 784, 787, 788, 789 

Lowes, Linda P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768 

Lowy, Douglas R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875 

Lu, Aiping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96, 367, 373, 769 

Lu, An. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 

Lu, Chao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 848 

Lu, Connie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 382 

Lu, Dao-Pei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859 

Lu, Jiamiao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 

Lu, Jing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 333 

Lu, Liang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 930 

Lu, Peijuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .468, 567, 766 

Lu, Qi Long. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .468, 567, 766 

Lu, Taihe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259, 284 

Lu, Yi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 536 

Lu, Yuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Lu, Yuanqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669 

Lu, Zhao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 672 

Lubelski, Jacek . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133, 551 

Lubow, Jay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 843 

Lucke, Colleen E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504 

Lucking, Daniel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404 

Luetge, Fabienne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 

Lukason, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 656 

Lukason, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664 

Luke, Garry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 690, 692 

Luke, Jeremy M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694 

Lulay, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43, 343 

Lulka, Hubert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 878 

Lundberg, Cecilia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301, 879 

Lundberg, Kathryn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 711 

Luo, Meihui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275 

Luo, Xiaoyan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 339 

Luo, Yuxia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Lupo Stanghellini, Maria Tersa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605 

Lütgehetmann, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Luxembourg, Alain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Luzi, Paola. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 720 

Lv, Yinghui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 923 

Lynn, Danielle L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613 


M 

Ma, Nan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677 

Ma, Qiangzhong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773 

Ma, Wenqin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131 

Ma, Zhijun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259 

Macauley, Shannon L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197 

Macedo, Antero . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 728 

Machitani, Mitsuhiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 682 

Machluf, Marcelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 582 

Machuca-R, Catalina. . . . . . . . . . . . . . . . . . . . . . . . . 886, 887, 894, 895 

MacLachlan, Timothy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 656 

MacLeod, A. Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Maczuga, Piotr . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 562, 564, 569, 847 

Mader, Emily K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364 

Madinaveitia-V, JA. . . . . . . . . . . . . . . . . . . . . . . . . . . 886, 887, 894, 895


Madoiwa, Seiji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188 

Maeda, Michiko Wada . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473 

Maeda, Yasushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Maeder, Morgan L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300, 686 

Maehara, Yoshihiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103, 523 

Maetzig, Tobias. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348 

Maeyama, Yoshihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 524 

Maezono, Rie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898 

Magdaleno, Susan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849 

Maggio, Aurelio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 

Magharious, Mark M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544 

Magnani, Zulma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 498, 631, 785 

Maguire, Albert M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196, 600 

Maguire, Casey A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 

Maguire, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626 

Mah, Cathryn S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104, 901 

Mahadev, Vaidehi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 501 

Mahdipoor, Parvin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 534, 810 

Mahmood, Faisal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447 

Mahmoud, Enas A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436 

Mahzad, Akbarpour . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 287 

Maisner, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 

Maisonobe, Thierry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Maiti, Sourindra N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353 

Maiti, Sourindra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 

Maitland, Stacy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194 

Maitra, Anirban. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 892 

Majzoub, Ramsey N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171 

Makkia, Rasha S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 748 

Malani, Nirav . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9, 612, 621, 635 

Maldonado, Maricela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168 

Malech, Harry L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345, 833 

Malech, Harry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379, 571 

Mali, Reut . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445 

Malik, Punam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 344, 613 

Malloy, Andrew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 595 

Mamman, Sara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260, 349 

Mancheño, Uxua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Mancini, Donna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601 

Mandel, Ronald J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 752 

Manfredi, Anna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542 

Manfredsson, Fredric P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 752 

Mangeot, Philippe E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 706 

Maniar, Jay M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 424 

Manni, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Manns, Michael P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790, 804 

Mannucci, Edoardo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Mano, Miguel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 614 

Manohar, Rohan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574 

Manoli, Irini . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452 

Manuel, Gidekel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 519 

Manunta, Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 

Mao, Hai-Quan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179 

Mao, Haoyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 204 

Mao, Yanxiong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 653 

Maples, Phil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457 

Maples, Phillip B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Maples, W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891 

Marchadier, Dawn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 

Marcotte, Joseph. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833 

Marcus, Assaf. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 

Marcy, Guillaume. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844 

Marie, Corinne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695 

Mariette, Xavier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Marini, Frank C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533 

Marino, Michael P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 

Markelc, Bostjan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448, 540 

Markovic, SN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891 

Markusic, David M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288, 663 

Maródi, Laszló. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Marozin, Sabrina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 793 

Marquez, Rebecca T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561 

Marrocco, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542 

Marschke, Christina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506 

Marsh, Christopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Marshall, Kathleen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600 

Marsic, Damien. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405 

Martens, Anton C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 715 

Martin, Douglas R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 194, 646 

Martin, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Martin, Paul T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 

Martínez-F, Francisco . . . . . . . . . . . . . . . . . . . 886, 887, 894, 895, 920 

Martino, Ashley T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .288, 402, 619 

Martinson, Laura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 868 

Marumoto, Tomotoshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 861, 925 

Marusich, Elena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725 

Maruyama, Kazuo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430, 483 

Maruyama, Riichiroh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523 

Marx, Howard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Marzioni, Daniela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295 

Marzulli, Marco. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 

Mascoop, Ethan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 596 

Mason, Jeffrey B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 

Massie, Bernard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143, 381 

Masurier, Carole . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Matabosch, Xavier. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461 

Matalon, Reuben. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 649 

Matar, Majed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Mathis, J. Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530, 912 

Matsufuji, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898 

Matsui, Hayato . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 682 

Matsumoto, Tae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451, 456 

Matsumoto, Takuya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Mattar, Citra N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 

Mattar, Citra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 253 

Matyunina, Lilya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 628 


172 


Mauleon, Itsaso . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Mavilio, Fulvio . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16, 98, 298, 612, 633 

May, Shannon M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8 

Mayer, F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Mazzacurati, Lucia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56 

McAnulty, Robin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 

McBride, Jodi L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 650, 837 

McBride, Martin W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 853 

McBryan, Tony . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 853 

McCaffrey, Anton P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561 

McCarty, Douglas M. . . . . . . . . . . . . . . . . . . . . . . . . 337, 616, 617, 662 

McClure, Diane. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

McClure, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727, 853 

McConnell, Bradley. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735 

McConnell, Kellie I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 666 

McConnell, Ruth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277 

McCormack, Natasha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626 

McCoy, Jay R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 701 

McCray, Jr., Paul B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271 

McCray, Paul B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 

McDonald, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 628 

McDonough, Samantha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .58, 410 

McDowell, Amy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 

McGee, Jeannine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 

McGinn, Arlo N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 560 

McGoogan, Katherine E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

McGowan, P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

McIlwraith, CW. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871 

McIntosh, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Mcintosh, Jenny. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 

McIvor, R. Scott. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14, 255, 702, 877 

McKenna, Robert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332 

McLaren, David G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

McLeod, Andrea. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

McMannis, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783 

McMenamin, Deirdre. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340, 874 

McNeer, Nicole Ali. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 

McPhee, Scott W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832 

McVey, John H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6 

Medina-Echeverz, José . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776 

Medina-Kauwe, Lali . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 843 

Meecham, Robert Q. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 718 

Mehta, Perdeep K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 262 

Meijer, Dimphna H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 546 

Meili, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 

Meisen, W. Hans. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362 

Melcher, Alan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361, 780 

Melero, Ignacio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Mena, Mayra G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 681 

Mena-Enriquez, Mayra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420 

Mendell, Jerry R.. . . . . . . . . . . . . . . . . . . . . . . . . .69, 467, 768, 867, 892 

Mendell, Joshua T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867, 892 

Mendelsohn, Farrell . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Mendes Madeira, Alexandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 

Mendizabal, Adam M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 

Meng, Cuixiang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165, 272 

Menne, Stephan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Merella, Stefania. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .264, 606, 607 

Merkel, Christian A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 643 

Merling, Randall K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833 

Mermod, Nicolas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 383 

Merry, Catherine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336 

Merten, Otto-Wilhelm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589 

Merzouki, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 881 

Messer, Harald G. P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1 

Mezey, Jason G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 653 

Mezzadra, Riccardo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298 

Mi, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213 

Mi, Tiejuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 353 

Miao, Carol H. . . . . . . . . . . . . . . . . . . . . . . . . . . 294, 442, 623, 625, 828 

Miao, Carol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260 

Miccio, Annarita. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98, 298, 633 

Michael, Drew. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Michel, Sadelain. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 

Miest, Tanner S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515, 517 

Miest, Tanner. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514 

Milbauer, Liming . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 822 

Millán, José L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451 

Millán, José. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 456 

Miller, Daniel G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 

Miller, Darren. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 281 

Miller, Dusty. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 

Miller, Erin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329 

Miller, Jeffrey C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 632 

Miller, Jr., Francis J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743 

Milligan, Graeme . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 727, 853 

Miltenyi, Stefan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 594 

Mimuro, Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188 

Min, Jung-Joon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 917 

Min, Liang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282 

Minai-Tehrani, Arash. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 929 

Mineharu, Yohei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 787, 789 

Mineno, Junichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777 

Mingozzi, F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Mingozzi, Federico . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .403, 600, 823 

Minskaia, Ekaterina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 690 

Mintz, Paul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559 

Mir, Lluis M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 703 

Miselli, Francesca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 633 

Miskin, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603, 750 

Mitani, Ko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315 

Mitchell, James B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642 

Mitrophanous, Kyriacos . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603, 750 

Mitsuyasu, Ronald. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266, 598 

Mittra, Arjun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Miura, Yoshiaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .241, 674, 911 



Miura, Yoshie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 925 

Miura, Yoshie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .97, 861 

Mixson, Archibald J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 

Miyake, Koichi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451, 456, 723, 754 

Miyake, Noriko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 456, 723 

Miyamoto, Shohei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 233 

Miyamoto, Yasuhide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 

Miyata, Satsuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 696 

Mizrahi, Olga . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 856 

Mizuguchi, Hiroyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573, 682 

Mizukami, Hiroaki . . . . . . . . . . . . . . . . . . . . . . . .88, 188, 573, 696, 791 

Mizuno, Ryoichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 433 

Mizusawa, Hidehiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 92, 553 

Moase, Elaine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 

Moats, Rex . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320 

Mockaitis, Keithanne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111 

Mockenhaupt, Stefan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127 

Modlich, Ute . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348 

Moerer, Petra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 715 

Moghimi, Babak. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405, 825 

Moguche, Albanus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349 

Mohammad, Husam K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 749 

Moiani, Arianna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298 

Moimas, Silvia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 532 

Molina Estévez, Francisco Javier . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Moll, Alyson L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 

Monahan, Paul E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832 

Mondino, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80 

Monnat Jr., Raymond J . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 900 

Monroe, W. Todd . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 

Monsurrò, Vladia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295 

Montane, Joel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334, 335 

Montazeri Aliabadi, Hamidreza . . . . . . . . . . . . . . . . . . .155, 534, 810 

Montesinos, Carlos A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261 

Montgomery, Chrystal L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 

Montini, Eugenio. . . . . . . . . . . . . .264, 383, 606, 607, 610, 611, 829 

Montpetit, Alexandre. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428 

Montus, Marie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 

Moom, Hyeong-Ho . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 734 

Moon, Anne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 

Moot, Robert. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .189, 778, 873 

Morachis, Jose M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436 

Morales, Pablo R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392 

Moran Cruz, Claudia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Morbitzer, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 

Moreau, Aurélie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 

Moreno, Amira Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 170, 283 

Moreno, Mario . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883, 899 

Morgan, Richard A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228, 231 

Mori, Shinji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 539 

Mori, Takeshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150, 172 

Morioka, Yuka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Morishita, Ryuichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736 

Moritz, Thomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .32, 369 

Morizono, Hiroki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 340 

Morizono, Kouki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609 

Morodomi, Yosuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523, 813 

Morral, Nuria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889 

Morris, John C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81, 410, 799 

Morris, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 

Morris, Kevin V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 554 

Morrison, Nancy E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646 

Moullier, Philippe. . . . . . . . . . . . . . . . . . . .72, 124, 195, 207, 375, 661 

Mroske, Cameron . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128 

Mrugala, Maciej . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 342 

Mu, Xin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404, 555 

Mueller, Christian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341 

Mueller, Peter E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482, 767 

Muench, Marcus O.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Muhammad, A. K. M. G.. . . . . . . . . . . . . . . . . . .59, 509, 784, 787, 788 

Muhammad, A. K. M. Ghulam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 789 

Muik, Alexander. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 641 

Mukai, Hidefumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443 

Mukherjee, Malini . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913 

Mukhopadhyaya, Rabindranath . . . . . . . . . . . . . . . . . . . . . . . . . . . 388 

Mukumoto, Hanae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 812 

Muller, Christian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 

Muller, Heike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529 

Mulligan, Richard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Mullins, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3, 45 

Mundt, Bettina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790 

Munn, David H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213 

Muñoz, Nina M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 637 

Murakami, Masahiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92 

Murakami, Yusuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222 

Muranski, Pawel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350 

Murphy, Sam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Murray, Christopher B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163 

Murray, Elizabeth E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 429 

Murtaugh, Michael P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427 

Murugesan, Selva . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883 

Musher, Benjamin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 496 

Mussolino, Claudio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 

Muthuramu, Ilayaraja. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737 

Muzyczka, Nicholas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 332 

Myers, Rae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 364 

N 

Naash, Muna I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 748 

Nace, Rebecca A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 802 

Nace, Rebecca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360 

Nagai, Yoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 861, 925 

Nagasaki, Yukio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305 

Nagata, Tetsuya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558 

Nagpal, Poonam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 415 


174 


Naik, Shruthi K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 360, 802 

Nair, Sangeeta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 243 

Naitza, Christopher S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . .397, 407, 659 

Nakagami, Futoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736 

Nakagami, Hironori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 736 

Nakai, Hiroyuki . . . . . . . . . . . 126, 129, 187, 397, 407, 476, 479, 659 

Nakamori, Masayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Nakamura, Akinori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473 

Nakamura, Takafumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359 

Nakamura, Tsutomu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Nakanishi, Masataka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179 

Nakanishi, Yoichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .103, 222, 233 

Nakao, Akimasa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Nakashiro, Koh-ichi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 418 

Nakauchi, Hiromitsu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312, 714 

Nalbantoglu, Josephine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 

Naldini, Luigi . . . . . . . . . . . . . . . . . . . . 93, 94, 267, 287, 290, 377, 498, 

. . . . . . . . . . . . . . . . . . . . . 604, 606, 607, 610, 611, 631, 632, 633, 829 

Nam, Hye Yeong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 161, 806 

Nam, Kwangwoo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434 

Nam, Kyungmin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 685 

Naranjo, Araceli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351 

Narasimha, Pavitra. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 842 

Narisawa, Sonoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451, 456 

Narrow, Wade . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 

Narumi, Kenta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235 

Narusawa, Megumi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 233 

Nasimuzzaman, Md . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 608 

Nassar, Boulos S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399 

Nassar, Boulos. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 654 

Nathwani, A. C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Nathwani, Amit C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 587 

Nathwani, Amit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46 

Naundorf, Sonja. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 343 

Navon, Gil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320 

Naylor, Stuart. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603, 750 

Nedeljkovic-Kurepa, Ana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 912 

Negishi, Yoichi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483 

Nègre, Didier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876, 893 

Nehete, Pramod. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488 

Nelson, Christopher E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 839, 841 

Nemunaitis, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457, 505 

Neri, Margherita. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 631 

Nettelbeck, Dirk M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139, 528 

Nettelbeck, Dirk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 378 

Newman, Nikki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272 

Ng, Joanna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Ng, Philip . . . . . . . . . . . . . . . . . . . . . . . . . 3, 45, 54, 136, 147, 277, 317, 

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .414, 419, 460, 488, 509, 784 

Ng, Rainer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 763 

Ng, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 396 

Ng, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3 

Ng, Yuk-Yin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Nguyen, Catherine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 928 

Nguyen, Juliane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 565 

Nguyen, Quynh V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 

Nguyen, Quynh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466 

Ni, Weihua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Nibu, Ken-ichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Nice, Katie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870 

Nichols, Timothy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 829 

Nickerson, Michael L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124 

Nicklin, Stuart A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729 

Nicolai, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Nicolaus, Anke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249 

Niebuhr, Birte . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Nienhuis, Arthur W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .256, 587, 602 

Niers, Johanna M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303, 307 

Nii, Takenobu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 861, 925 

Niidome, Takuro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150, 172 

Niizawa, Gabriela A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74, 476, 479 

Nik-Ahd, Farnoosh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 470 

Nikhamin, Yan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 495 

Nimesh, Surendra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 904 

Nishikawa, Makiya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 812 

Nishikawa, Yoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 520, 803 

Nishina, Kazutaka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .92, 553 

Nishina, Tomoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553 

Nishiyama, Akiyo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473 

Nitahara-Kasahara, Yuko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 764 

Niu, Jing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 672 

Nixon, Alan J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .316, 477, 480 

No, Daniel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774 

Noble, Misty L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .442, 623, 625 

Nokisalmi, Petri. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .77, 795 

Nolta, Jan A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 

Nomoto, Shuji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Nonnenmacher, Matthieu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398 

Nonomura, Norio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 

Noordman, Yvet. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 

Norvell, Fabienne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Noske, Nadja . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 630 

Nounou, Mohamed I.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735 

Noviello, Maddalena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605 

Nowicki, M. Oskar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362 

Nowrouzi, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 

Nowrouzi, Ali. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46, 223, 343, 632 

Nukaya, Ikuei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777 

Nukiwa, Toshihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531 

Nuovo, Gerry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361, 891 

Nusco, Edoardo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 454 


O 

O’Callaghan, Cristopher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106 

O’Connor, Deirdre M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 907 

O’Dea, Shirley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626


O’Donnell, Patricia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43, 726 

O’Malley, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599 

O’Malley, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 

O’Neill, Ann Marie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138 

O’Reilly, Richard J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230 

O’Sullivan, Gerald C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .511, 535, 906 

Oakland, Mayumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 

Obach, Merce . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334, 335 

Oberg, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 801, 807 

Ochiya, Takahiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235 

Oda, Masafumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 705 

Odaka, Yoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 912 

Odegard, J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Odom, Guy L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36, 466, 472 

Odon, Valerie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 692 

Oh, Anthony . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 370, 761, 772, 856 

Oh, Seeun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818 

Oh, Wonil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 580 

Ohashi, Kazuo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190, 440 

Ohashi, Toya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714, 721 

Ohira, Shinga. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88 

Ohkouchi, Shinya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 531 

Ohlemiller, Kevin K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 717 

Ohmine, Ken . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 791 

Ohmine, Seiga . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311 

Ohmori, Tsukasa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188, 190 

Ojeda, Sergio R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 650 

Okabe, Motohito . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312 

Okada, Hironori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473, 764 

Okada, Michiyo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 861, 925 

Okada, Starlyn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 

Okada, Takashi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473, 764 

Okamoto, Sachiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777 

Okamoto, Shinya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Okamura, Haruki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 524 

Okamura, Nobutaka. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 524 

Okano, Shinji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 861 

Okano, Teruo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190, 440 

Okazaki, Jin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Okazuka, Kiyoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251 

Olafsen, Tove . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609 

Olivares, Simon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 224, 234, 354, 500 

Oliveira, Giacomo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605 

Oliveira, Satiro N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 

Olsen, John C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274 

Olson, Erik M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258 

Olson, Erik R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 255 

Oneal, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410, 799 

Oneal, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 

Onimaru, Mitsuho. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Onishi, Akira. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 696 

Onodera, Masafumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312 

Onohara, Toshihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Øpstad, Christer L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153 

Opyrchal, Mateusz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365 

Orban, Paul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334 

Orimo, Hideo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 456 

Ortved, Kyla O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477 

Osada, Kensuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 

Osada, Takuya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289 

Osborn, Mark J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 686 

Osborne, William R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 

Ostberg, Julie R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .38, 352 

Ostertag, Derek . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Osting, Susan M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670 

Ostrowska, Alina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 854 

Otani, Yuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443 

Otoi, Takeshige. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 

Otsu, Makoto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312, 714 

Otsuka, Makoto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154 

Otsuki, Naoki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Otte, Jürgen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 641 

Ou, Wu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31, 382 

Ouellet, Dominique L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 304 

Ousterout, David G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422 

Owusu-Boaitey, Nana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830 

Ozawa, Keiya . . . . . . . . . . . . . . . . . . . . . . . . . . . . .88, 188, 573, 696, 791 

P 

Pacholska, Agnieszka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 816 

Pack, Daniel W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 

Pagano, Claudio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Pagovich, Odelya E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652 

Pahnke, Jens . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411 

Pai, Sung-Yun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 

Paila, Kalyan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 465 

Pala, Mauro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 610 

Palapattu, Ganesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513 

Paleari, Ylenia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298 

Palfi, Stephane . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Palmer, Abbygail A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169 

Palmer, Donna J. . . . . . . . . . . . . . . . . . . . . . . . 3, 45, 54, 136, 147, 277, 

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .317, 414, 419, 460, 488, 509, 784 

Pan, Dao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .40, 306 

Pan, Jason. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345 

Pandey, Sanjay K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Pandha, Hardev . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361 

Pang, Jijing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199 

Pankert, Teresa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 394 

Pankhong, Panyupa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

Papayannopoulou, Thalia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 

Pappen, Beena O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Pâques, Frédéric. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .425, 428, 576 

Pardo, Luis A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 570 

Pardo, Luis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 850, 851 


176 


Pardridge, William M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 

Paredes-Gamero, Edgar Julian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 446 

Park, Jae Hyung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817 

Park, Jeong H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Park, Ji Hwan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279, 549 

Park, Jung-Heun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 707 

Park, Kkothanahreum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297 

Park, Morag . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Park, Sung-Jin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 929 

Park, Tae Gwan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166 

Park, Yong Serk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .158, 160, 435 

Parker, Alan L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6 

Parker, Matthew. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669 

Parker, Maura H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 

Parrish, Colin R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 374 

Parsons, David W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .273, 278, 281 

Partali, Vassilia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153 

Partanen, Kaarina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 795 

Paruzynski, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43, 343 

Paschon, David E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498, 648 

Paschon, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Passineau, Michael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 465 

Pastore, Joseph. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Pastore, Nunzia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 317, 454 

Patel, Ami . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212, 216 

Patel, Bella . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 

Patel, Ekta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 211 

Patel, Manij. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274 

Patel, Priti . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 

Patil, Rajesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179 

Patron, Juan P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 

Paulk, Nicole K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48 

Paulmurugan, Ramasamy . . . . . . . . . . . . . . . . . . . . . . . .541, 644, 645 

Paulson, Henry L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 846 

Paul-Wetterberg, Gabriella. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229 

Pauly, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601 

Paweska, Janusz. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 556 

Paya, Monica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 431 

Peccatori, Jacopo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605 

Pechnick, Robert N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509, 784 

Pedersen, Alexandra G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 760 

Pegram, Hollie J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239 

Pei, Duanqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 863 

Pelled, Gadi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 370, 761, 772 

Pellenz, Stefan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 900 

Pellin, Danilo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .98, 612 

Pellina, Danilo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264 

Penaud-Budloo, Magalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124 

Pence, Casey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Peng, Bo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 

Peng, Ching-An . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178 

Peng, Jianxiong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 698 

Peng, Kah-Whye. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .364, 794, 888 

Peng, Ling. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 928 

Peng, Yibing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213 

Penn, Marc S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Perebeov, Alexander . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 912 

Pereira, Linus Q. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851 

Pérez, Belen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 

Perez-Pinera, Pablo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422 

Perlson, Eran . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618 

Perrin, George Q. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 619 

Persons, Derek A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .262, 346, 608 

Persson, Jonas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2, 18, 78, 226, 815 

Pertschuk, Daniel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Peschanski, Marc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 706 

Pesonen, Sari. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77, 295, 795 

Petek, Lisa M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 

Petrs-Silva, Hilda. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 753 

Petry, H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 

Petry, Harald . . . . . . . . . . . . . 133, 183, 551, 562, 564, 566, 569, 847 

Pettersson, Pelle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Pfaff, Nils . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369 

Pfizenmaier, Klaus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357 

Pham, Nhung P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840 

Phan, Haley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116 

Philipson-Weiner, Lindsey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504 

Phillips, JN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 871 

Phillips, Neil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 148, 424 

Philpott, Nicola J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 822 

Philpott, Nicola. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 255 

Piao, Wenying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553 

Piccolo, Pasquale . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 317, 460 

Pierce, Eric A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600 

Pierson, Tyler M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 882 

Pietruszka, Marvin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774 

Piguet, Françoise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Pike, Lisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 307 

Pike-Overzet, Karin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Pikkarainen, Jere . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 816 

Pilla, James J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725 

Pinard, Maxime. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 

Pinnamaneni, Kranthi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Piovani, Bianca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588 

Pisera, Daniel A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 788 

Pitzer, Mark R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 650 

Plati, Tiziana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 611 

Plesa, Gabriela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Plinkert, Peter K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 798 

Plotkin, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Plump, Andrew S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Poddar, Minakshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96 

Poderycki, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144 

Podetz-Pedersen, Kelly M. . . . . . . . . . . . . . . . . . . . . . . . . . 14, 702, 877 

Podhajcer, Osvaldo L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238, 519 

Podsakoff, Gregory M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 823 



Poeschla, Eric M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 

Pointreau, Adeline. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 902 

Poirot, Laurent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425, 576 

Polach, Kevin J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Polacino, Patricia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485 

Poletti, Valentina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98 

Pollok, Jörg-Matthias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Poncz, Mortimer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257 

Ponder, Katherine P. . . . . . . . . . . . . . . . . . . . . . . . . . . 43, 718, 719, 726 

Pondugula, Satyanarayana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256 

Ponnazhagan, Selvarangan. . . . . . . . . . . . . . . . . . . . . . . . . . . 323, 615 

Ponomarev, Vladimi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Poon, Steven . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Poon, Wai S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819 

Porada, C. D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873 

Porciatti, Vittorio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 

Portales-Casamar, Elodie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Porteus, Matthew H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 634, 648 

Pouliot, Yannick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 

Poulsen, Hans Skovgaard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 905 

Powell, Jr., Daniel J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 782 

Powell, Suzanne Z. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 781 

Power, Shelby T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670 

Prantner, Andrew M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163 

Prausnitz, Mark R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 628 

Préat, Véronique. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695 

Preston, Thomas J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 

Preuss, Ellen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 641 

Price, Brandee A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Prieto, Jesús . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776 

Prikhodko, Olga . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 

Prill, Jan-Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 416 

Prockop, Darwin J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105, 531 

Prosser, Megan E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 499 

Proto, Jonathan D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 367, 373 

Provasi, Elena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80, 498, 631 

Provost, Nathalie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 

Provost, Patrick . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 304 

Pruzynski, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347 

Psatha, Nikoleta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Puig, Meritxell . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417 

Pulicherla, Nagesh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 328 

Pulido, Jose . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 780 

Pulliam-Leath, Anna C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 

Pun, Suzie H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65, 174, 177, 426 

Pungente, Michael D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153 

Puntel, Mariana . . . . . . . . . . . . . . . . . . . . . . . . . .59, 509, 784, 787, 789 

Puppo, Agostina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 542 

Puri, Nitin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849 

Puri, Raj K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 

Pützer, Brigitte M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411 

Q 

Qasim, Waseem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759 

Qian, Kun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 739 

Qiao, Chunping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .52, 468 

Qin, Elizabeth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 717 

Qin, Qiuyue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 

Qin, Yuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639 

Qiu, Jianping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 652 

Qiu, Jinlang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218, 391 

Qu, Jinrong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .30, 263 

Qu, Yanyan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232 

Quach, Eric T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 907 

Quetglas, Jose I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776 

Quinn, Thomas P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 

Quintanilla, Rene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 144 

Quintino, Luis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301 

Quiviger, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Quiviger, Mickaël. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695 

Qureshi, Ammar T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176 

R 

Rabinowitz, Joseph. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725 

Rader, Daniel J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102 

Radrizzani, Marina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 829 

Radu, Antonetta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 823 

Radvanyi, Laszlo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 

Raff, Gary W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286 

Rafi, Mohammad A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 720 

Raggi, Eugene. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74 

Rah, Dong Kyun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140 

Rai, Lena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363 

Raimondi, Laura. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Raja, Srinivasa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 749 

Raki, Mari . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295 

Ralph, Scott . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Ramakrishnan, Aravind . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257 

Ramakrishnan, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 702 

Ramamoothy, Meera . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 718 

Ramirez, Juan C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 431 

Ramlogan, Charmaine A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 

Rammelt, Stefan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469, 482 

Ramos, Julian N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 475, 762 

Ramsey, Austin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Randhawa, Sandeep . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 808 

Ranzani, Marco. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 607, 610, 611, 829 

Rao, Anitha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .99, 586 

Rao, Han Zhi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 720 

Rao, Mahadev . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228 

Rao, Nagesh P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Raoul, Sylvie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Rapti, Kleopatra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 668 

Raschke, James J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 670 

Rassi, Anahita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 


178 


Ratner, Dmitry. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404 

Rauschhuber, Christina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299, 378 

Rawlings, David J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35, 260, 349, 687 

Read, Stanley E . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 897 

Rea-Ramsey, Angela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Reay, Daniel P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74 

Rebar, Ed. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Rebar, Edward J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 

Recchia, Alessandra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16, 612, 633 

Reed, Charles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883 

Reed, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Reichenbach, Janine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347, 390 

Reik, Andreas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26, 423, 498, 903 

Reilly, Meghan J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175, 914 

Reineke, Theresa M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 

Reinhart, Bonnie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53, 56 

Reiser, Jakob . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31, 382 

Reiss, U. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Rementer, Cameron . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 741 

Remy, Philippe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 603 

Ren, Dong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639 

Ren, Gaoying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10, 474 

Ren, Yong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179 

Rentsendorj, Altan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 843 

Renzi, Christopher. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Resende, Fernando F. B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 850 

Ressler, Julie A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351 

Restifo, Nicholas P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350 

Reuser, Arnold J. J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713 

Reynolds, Holly M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 

Reyon, Deepak . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300 

Rhee, Byung D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Rice, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Rice, Karen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 

Richard, Magali. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695 

Richardson, Dean W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 

Richardson, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212 

Richter, Maximilian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 

Riddell, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Riddell, Stanley R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 

Riera-Knorrenschild, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Riggs, Arthur D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 550 

Riggs, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 575 

Rigolet, Aude. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Riley, James L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292 

Rinkoski, Tommy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 

Ripamonti, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Rising, Aaron C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 752 

Ritsema, Tita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 564 

Rivera, Angel A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 912 

Rivera, Hector . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128 

Rivers, Angela E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 327 

Rivière, Isabelle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30, 230, 263, 791 

Rizzardi, Gian-Paolo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588 

Rizzi, Ermanno . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .98, 612 

Robbins, Paul D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .96, 367 

Robbins, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Robbins, Zachary J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159 

Roberts, Alison . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Roberts, Jeffrey N . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875 

Roberts, Marie S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197 

Rocca, Céline. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Rocchi, Palma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 928 

Rockey, William M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834 

Rodgers, John. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 820 

Rodichenko, Nikita S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Rodijk, Mark. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Rodino-Klapac, Louise R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 

Rodriguez, Ron. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 

Rodriguez, Stephen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 597 

Rodriguez-Lebron, Edgardo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 846 

Roeder, Ingo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Roescher, Nienke. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Roffler, Steve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226 

Roh, Jae-Kyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 880 

Rokkam, Venkata . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 726 

Rolling, Fabienne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 

Romano, Valentina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 

Romero, Norma B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Rommelfanger, Diana M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 358, 361 

Roncarolo, Maria-Grazia . . . . . . . . . . . . . . . . . . . . . 287, 290, 377, 604 

Rooney, Cliona M. . . . . . . . . . . . . . . . . . . . . . 15, 20, 84, 496, 503, 591 

Rosales, C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Rosales, Xiomara Q.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768 

Rosas, Lucia E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617 

Rose, Laura. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 162 

Rose, Scott D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271 

Rosenberg, Jonathan B. . . . . . . . . . . . . . . . . . . . . . 170, 283, 652, 821 

Rosenberg, Steven A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228, 231 

Rosenkranz, Andrey A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Rosewell, Amanda. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .147, 277, 414 

Rosier-Montus, Marie-Françoise . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Rosoff, Howard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 903 

Rossi, John J. . . . . . . . . . . . . . . . .89, 99, 118, 265, 304, 489, 493, 559 

Rossi, Paolo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267 

Rotella, Carlo Maria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Roth, Shoshannah L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9, 635 

Rothschilds, Adrienne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442 

Rott, Yvonne . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506, 507 

Roujeau, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Rouseau, Joël . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428 

Rouvinen-Lagerström, Noora . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 

Rouy, Didier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Rowley, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357 

Roy, Andre J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 592 

Roy, Jackie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366 



Roy, Soumitra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19, 292 

Rozemuller, Henk. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 715 

Rozengurt, Nora. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Ruben, Boado . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 

Ruggeri, Marco. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203 

Ruggiero, Eliana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223 

Ruiz, Rafaela. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889 

Ruozi, Giulia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 728 

Rushing, Elisabeth J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 747 

Russell, David W.. . . . . . . . . . . . . . . . . . . . .10, 120, 258, 384, 474, 493 

Russell, Stephen J. . . . . . . . . 360, 364, 538, 794, 802, 877, 888, 893 

Rustagi, P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Rutcliffe, Sarah J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 

Rutledge, John C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286 

Ruzo, Albert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 

Ruzsics, Zsolt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 679 

Ryals, Renee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199 

Ryan, Christine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 

Ryan, Martin D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 690, 692 

Ryffel, Bernard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Ryu, Byoung Y. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260, 349, 637, 687 

S 

Sachidanandam, Ravi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 

Sack, Brandon K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 825 

Sadeghi, Arian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 502 

Sadelain, Michel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30, 230, 791 

Saenz, Dyana T.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 

Sætrom, Pål . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559 

Safinya, Cyrus R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 171 

Sagawa, Hiroaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141 

Sagner, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 507 

Saha, Sunandan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 

Sahaghian, Arineh. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 

Sahakyan, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 

Sahenk, Zarife . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .768, 69 

Sahin, Tevfik T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Saifuddin, Sameer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735 

Saini, Massimo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94 

Saito, Satoru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523, 813 

Saito, Yasushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 

Sakai, Atsushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 723 

Sakamoto, Chika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 233 

Sakamoto, K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 886, 895 

Sakamoto, Kouichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898 

Sakata, Yoichi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188, 190 

Sakr, Hany I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 530 

Saksela, Kalle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 684 

Sakurai, Fuminori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 682 

Salanti, A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Salazar-Montes, Adriana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420 

Salem, Alireza . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 509, 784 

Saleme, Vera . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742 

Salmon, Florence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 551 

Salmons, Brian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 869 

Salomon, Daniel R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 712 

Salomoni, Monica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 604 

Salsman, Vita S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .496, 781, 913 

Saltzman, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 702 

Saltzman, W. Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 

Salvatori, Francesca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588 

Samaranayake, Haritha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 816 

Samoto, Vivian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742 

Sampath, Padma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412 

Sampath, Prakash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 

Sampedro, Ana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Samson, Mélanie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5 

Samuel, Isaac. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655 

Samulski, R. Jude . . . . . . . . . 395, 548, 585, 620, 634, 651, 832, 871 

Sanchez, Ceidy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513 

Sanda, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 873 

Sandadi, Samith. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 495 

Sander, Jeffry D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300 

Sandoval, Ana S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 681 

Sandoval, Ivette M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Sandoval-Rodriguez, Ana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 420 

Sandoval-Z, Hugo . . . . . . . . . . . . . . . . . . . . . . . . . . . 886, 887, 894, 895 

Sands, Mark S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197, 717 

Sangermano, Riccardo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 460 

Sankaranarayanan, Jagadis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436 

Sano, Asami . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434 

Santacruz, Rene A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 202 

Santhekadur, Prasanna K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242 

Santillan, Jazmin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 681 

Sanvito, Francesca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 610 

Saraiva, Luisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156 

Sardesai, Niranjan Y. . . . . . . . . . . . . . . . . . . . . . . . . . . 22, 429, 504, 701 

Sardi, Pablo S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 205 

Sareen, Dhruv . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 

Sargent, R. Geoffrey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Sarkar, Devanand. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242 

Sartori, Daniela . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298 

Sarwari, Roya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 254 

Sasaki, Erika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .97, 861 

Sasaki, Yoshihiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434 

Sastry, Jagannadha. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 488 

Sather, Blythe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260, 349 

Sauthoff, Harald . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 415 

Sauvageau, Guy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372 

Savoldo, Barbara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 785 

Sawall, Stefanie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .514, 521, 528 

Saxena, Romil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889 

Scaramuzza, Samantha. . . . . . . . . . . . . . . . . . . . . . . . . . .264, 267, 604 

Scari, Puthupparampil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66 

Scaria, Abraham. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 656, 664 

Schache, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 804 


180 


Schaer, Gary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Schaffer, David V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 122, 654, 840, 872 

Schambach, Axel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41, 269, 348, 369 

Scharenberg, Andrew M. . . . . . . . . . . . . . . . . . . . . . . . . . . 35, 637, 687 

Schenkwein, Diana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 

Scherer, Lisa J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489 

Scherman, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439, 695 

Scheule, Ronald K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165 

Schiestl, Robert H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Schietinger, Andrea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356 

Schiffer-Mannioui, Cécile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425 

Schiller, John T . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875 

Schirmbeck, Reinhold . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 

Schleifman, Erica B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 

Schliesser, Maximilian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 

Schmelzer, Leah. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 392 

Schmid, Manfred . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347 

Schmidt, Anke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411 

Schmidt, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82, 87, 123 

Schmidt, Manfred . . . . . . . . . . . . . . . . . . . . .42, 43, 46, 223, 264, 269, 

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .343, 383, 389, 607, 610, 611, 632 

Schmidt, Manuel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506, 507 

Schmidt, Warren N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561 

Schmoll, H. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Schneider, Irene . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386 

Scholler, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Scholler, Nathalie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163 

Scholz, Simone. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269, 389 

Schowalter, David B . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 877 

Schreiber, Hans. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356 

Schreiber, Karin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356 

Schroff, M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82, 87 

Schrump, David S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228 

Schubert, Kathryn M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371 

Schubert, Kathryn . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 574 

Schultz, Brian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762 

Schwartz, Marc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910 

Schwarze, Ulrike. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 474 

Scimeca, Michael S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 316, 480 

Scott, David W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830 

Scott, Emma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200 

Scott, Tristan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 556 

Segall, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 502 

Seger, Reinhard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347, 390 

Segovia, Mercedes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 

Segura, Maria Mercedes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417 

Segura, Tatiana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 168 

Sekar, Thillai V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 644, 645 

Sekine, Shoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483 

Selby, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361, 780 

Semechkin, Andrey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100, 854 

Semechkin, Ruslan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100, 854 

Semenova, Ekaterina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759 

Sénac, Julien S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452 

Sénac, Julien S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8, 152, 452 

Sena-Esteves, Miguel . . . . . . . . . . . . . . .130, 194, 546, 646, 649, 745 

Senyukov, Vladimir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 508, 903 

Senzer, Neil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Sepe, Rosa Maria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 317, 454 

Seppen, Jurgen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 858 

Sergi Sergi, Lucia . . . . . . . . . . . . . . . . . . . . . . . 267, 377, 607, 610, 829 

Sergijenko, Ana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336, 716 

Serra, Montserrat. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461 

Sersa, Gregor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448, 540 

Servais, Laurent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 

Sest, Maike . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 879 

Seth, Prem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675 

Sevin, Caroline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Seyfried, Thomas N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 646 

Sgouramali, Eleni. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Sgualdino, Jacopo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606, 611 

Shababi, Monir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 455 

Shaban, Mona. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 567 

Shackleton, Cedric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461 

Shafer-Weaver, Kimberly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899 

Shaffer, Donald R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 

Shafiani, Shahin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 491 

Shah, Priya S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 840 

Shah, Vinit. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Sharma, Anurag . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 490 

Sharma, Priyanka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7 

Sharma, Rajiv. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Sharon, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 808 

Shaw, Aaron. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 590 

Shawler, Daniel L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 814 

Shayakhmetov, Dmitry M. . . . . . . . . . . . . . . . . . . . . . . . . . . 4, 409, 491 

Shedlock, Devon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

Shen, Hong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157 

Shen, Shen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 393 

Shen, Xuefei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22, 429 

Shen, Ying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 415 

Sheng, Jackie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 671 

Shenker, Larrisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Sherman, Mark . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 

Sherman, Warren. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 

Sheyn, Dima . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 856 

Sheyn, Dmitriy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .320, 370, 761 

Shi, Donglu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 

Shi, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537 

Shi, Julie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 174, 177 

Shi, Junwen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391 

Shi, Weijie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 247 

Shi, Yijun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 882 

Shi, Yimin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 

Shibata, Masa-Aki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 

Shida, Hisatoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359 



Shields, Jordan E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189, 778 

Shih, Chia-Chiao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 512 

Shihabuddin, Lamya S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201, 205 

Shikada, Yasunori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523 

Shikano, Toshio. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 803 

Shiku, Hiroshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777 

Shim, Min Suk. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116, 164 

Shimada, Hideaki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Shimada, Takashi . . . . . . . . . . . . . . . . . . . . . . . . .88, 451, 456, 723, 754 

Shimada, Yohta. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 721 

Shimizu, Keiji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248 

Shimizu, Saki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 

Shimokawa, Mototsugu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Shin, Jin-Hong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473, 771 

Shin, Ji-Young . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 909, 929 

Shin, Jung Ah . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 740 

Shin, Young Eun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158, 160 

Shine, Jui-Hung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 927 

Shirakawa, Toshiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Shirley, Shawna A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 441 

Shontz, Kim M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 892 

Shpall, Elizabeth J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20, 353 

Shukla, Ravi S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845 

Shultz, Leonard D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90 

Shumann, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 808 

Sibilia, Jean. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Sicard, Flavie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 878, 902 

Siegal, Gene P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 

Siegel, Don L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186 

Siemann, Dietmar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Sievers, Richard E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Sikorski, Rachel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412 

Silberg, Jonathan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 408 

Siler, Ulrich . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 347, 390 

Silva, Guilherme. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735 

Silva, Simoneide S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 851 

Silve, Aude . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 703 

Sim, Sotcheadt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 904 

Simone, Scholtz . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 383 

Simons, David L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Simpson, Dana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 262 

Simpson, Elizabeth M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Sims, Jason. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423 

Sin, Jeong-Im . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236 

Sinai, Pedram . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774 

Singh, Harjeet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 224, 354 

Sinn, Patrick L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 

Sirvente, Raquel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742 

Siu, Karen K. W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 278 

Sivaraman, Sara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 

Skog, Johan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 

Skuk, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 471 

Slater, John H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 666 

Slawin, Kevin M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783 

Sleep, S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Sleep, Susan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379, 587 

Sleeper, Meg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 719, 726 

Slepushkin, V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Sliwka, Hans-Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153 

Slobodkin, Gregory. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Slough, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Slovin, Susan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Small, Juliana C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680 

Smerdou, Cristian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 776 

Smith, Bruce F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138 

Smith, Jeffrey S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 

Smith, Julianne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425, 576 

Smith, Laura J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329, 663 

Snapper, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 

Snyder, Brooke R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 907 

Snyder, Milo C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442 

Snyder, Richard O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124 

Soballe, Kjeld. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 760 

Sobolev, Alexander S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Soden, Declan M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 511 

Soe, Yatanar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Soldati, Corrado . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605 

Soldner, Frank . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 

Soltys, Stephen M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585 

Somanathan, Suryanarayan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292 

Somanchi, Srinivas S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 240 

Somia, Nikunj V . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 877 

Sommer, Nadine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411 

Sondhi, Dolan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195, 200 

Song, Degang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 782 

Song, Jae J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818 

Song, Lina. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 

Song, Liu-jiang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824 

Song, Shuxian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625 

Song, Sihong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669 

Song, Xiao-Tong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 

Sonpavde, Guru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783 

Soong, Bing-Weng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 846 

Sorenson, Brent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 702 

Sorg, Ursula R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Sorge, Randy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Sorrentino, Brian P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .259, 284, 379 

Sorrentino, Cristina N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 722 

Sorrentino, Nicolina C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401 

Sorzano, Carlos Oscar S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 916 

Sosale, Nisha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 

Soukhatcheva, Galina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334, 335 

Soustek, Meghan S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104, 901 

South, Andrew P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 

Sowers, Anastasia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642 

Spaeth, Erika L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533 


182 


Spampanato, Carmine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401, 722 

Sparks, Jeff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Sparwasser, Tim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790 

Speiser, Daniel E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 228 

Spencer, David M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783 

Spencer, H. Trent . . . . . . . . . . . . . . . . . . . .28, 826, 189, 592, 778, 873 

Spencer, Jacqueline F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518 

Spengler, Ryan M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 837, 842 

Spratt, S. Kaye . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544 

Spriggs, David R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 495 

Springer, Matthew L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Springfeld, Christoph. . . . . . . . . . . . . . . . . . . . . . . . . . . . .110, 515, 798 

Squillace, Karen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311 

Srivastava, Alok. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121 

Srivastava, Arun . . . . . 121, 131, 288, 330, 402, 406, 619, 663, 827 

Staal, Frank J. T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

Stachler, Matthew D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 662 

Stacpoole, Peter W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406 

Stamatoyannopoulos, George. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 

Stamatoyannopoulos, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 

Stanic, Bojana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743 

Stapleton, Gary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3 

Starr, Renate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351 

Steel, Jason C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 

Stefania, Merella. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 611 

Stefanni, Alice C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Stefansk, Jolanta . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Stegmüller, Carolin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 

Stein, Stefan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 269 

Steines, Benjamin R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399, 654 

Steinhoff, Gustav . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677 

Stephen, Gottschalk M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 

Stewart, Phoebe L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4 

Stock, Stuart . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675 

Stocking, Carol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Stok, Merel M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713 

Stolz, Donna B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 858 

Stone, Jennifer D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 356 

Storb, Rainer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73, 76 

Storici, Francesca. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693 

Storkus, Walter J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232 

Stornaiuolo, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588 

Stout, Steven J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Strauss, Bryan E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 643 

Strauss, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2, 18, 852 

Streeter, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743 

Stremmel, Wolfgang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 110 

Stritzker, Jochen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Strob, Rainer F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623 

Struever, Nina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790, 804 

Stuckey, Samantha A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 693 

Stühmer, Walter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .570, 850, 851 

Su, Qin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400, 404, 555, 649, 827 

Su, Susan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 761 

Su, Xiaomin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 755 

Su, Yun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 

Subat, Yosuf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 

Subr, Vladimir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 416 

Suda, Takeshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 627, 705 

Sudres, Muriel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Suerth, Julia D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348 

Suga, Tomohiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Sugae, Takashi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 520 

Sugano, Hanako. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451 

Sugimoto, Hiroyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Suh, Junghae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 408, 666 

Sui, Hongshu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270 

Sule, Gautam. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 478, 820 

Sullivan, Deborah E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Sullivan, Jennifer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664 

Sullivan, Millicent O. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .169, 175, 914 

Suman, V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891 

Sun, Baodong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338 

Sun, Bingbing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157 

Sun, Bo K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 818 

Sun, Guihua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559 

Sun, Junjiang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832 

Sun, Junwei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600 

Sun, Pengyu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391 

Sun, Samuel S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442 

Sun, Samuel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 625 

Sun, Wenchao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432 

Sun, Xingshen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270 

Sunshine, Abraham N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642 

Surace, Enrico M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .401, 542, 722 

Suree, Tom . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 

Surosky, Richard. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544 

Suwanmanee, Thipparat. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 832 

Suzuki, Hidenori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 723 

Suzuki, Keiichiro. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315 

Suzuki, Masataka . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54, 478, 820 

Suzuki, Ryo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430, 483 

Suzuki, Sachie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312 

Suzuki, Takayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 682 

Svendsen, Clive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 

Sverdlov, Eugene D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Svinartchouk, Fedor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 661 

Swanson, Douglas J.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Swanson, Magdalena I. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Sweeney, Colin L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .345, 571, 833 

Sweeney, Lee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 

Sweitzer, Sarah M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 749 

Swiderski, Piotr . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 

Sysol, Justin R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452 

Szabolcs, Paul . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 

Szakmary, Akos. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 



Szalay, Aladar A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Szoka, Francis C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 565, 568 

Szucs, Sylvia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 649 

T 

Tabata, Toshiaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577 

Tachibana, Yoichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181, 581 

Tacquet, Nicolas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Tada, Yuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Tae, Hwang H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599 

Taejin, Song . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678 

Tagalakis, Aristides D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 106, 156 

Tagawa, Masatoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .282, 524, 805 

Täger, Maike. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Tahara, Hideaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359 

Tahiri, Sanaa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 

Tai, Chien-Kuo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 522 

Tai, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Tai, Khalid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301 

Tait, Andrew S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 450 

Tak, Paul Peter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Takahashi, Atsushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .97, 861 

Takahashi, Hiroshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 754 

Takahashi, Yuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 812 

Takakura, Yoshinobu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 812 

Takamatsu, Hideo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898 

Takayama, Koichi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 233 

Takeda, Shin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 526, 803 

Takeda, Shin’ichi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .473, 558, 764 

Takiguchi, Yuichi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Takiya, Christina M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742 

Talbott, Kendra T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504 

Tamamoto, Atsuko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 524 

Tamsett, Thomas J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201 

Tan, Gewen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 520, 803 

Tan, Meng-qun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824 

Tan, Rusung . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334 

Tan, SzeHuey. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Tan, Wanlong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391 

Tanaka, Hiroyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 172 

Tanaka, Shigeaki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 

Tanaka, Shinji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 732 

Tanaka, Yoshihiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 233 

Tang, Qiushi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 

Tang, Ru-Hang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468 

Tang, Ruhang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52 

Tang, T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896 

Tang, Winson. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598 

Tang, Ying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 96, 367, 758, 769 

Tang, Yuqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773 

Tangney, Mark. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535 

Tani, Kenzaburo . . . . . . . . . . . . . . . . . . . . . . . . . .97, 222, 233, 861, 925 

Taniguchi, Akiyoshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440 

Tanio, Masami. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 462 

Tannous, Bakhos A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .130, 303, 307 

Tanoue, Kiyonori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898 

Tao, Mi-Hua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 

Tapscott, Stephen J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73, 76 

Tareen, S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Tatsumi, Kohei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190, 440 

Tatsumi, Koichiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Taub, Jason S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651 

Tawackoli, Wafa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320, 761, 772, 856 

Taylor, Amy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 262 

Taylor, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896 

Taylor, Clare . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 230, 263 

Taylor, Jennifer L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232 

Tazawa, Hiroshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797, 800 

Tebbets, Jessica C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373 

Tecedor, Luis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870 

Teissie, Justin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448 

Temme, Achim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521 

ten Dijke, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765 

Tennant, Bud C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 215 

Teo, Marissa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Terada, Nobuyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 524 

Tesarfreund, Matthew . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 

Tesfay, Mulu Z. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 888 

Tevz, Gregor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448 

Thaci, Bart. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 683, 915 

Thatava, Tayaramma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 311 

Thayapararajah, Mahinthan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 544 

Theisen, Linda. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .669, 881, 904 

Theobald, Matthias. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221 

Thibault, Marc. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .699, 881, 904 

Thiel, William H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 743 

Thies, Verena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 348 

‘t Hoen, Peter A. C.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765 

Thomas, Brandon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 251 

Thomas, Darby L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 593 

Thomas, Terry E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 860 

Thomaschewski, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Thompson, Craig B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291 

Thompson, Cynthia D . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 875 

Thompson, J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896 

Thompson, Jill M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . 358, 361, 775, 780 

Thompson, John A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 

Thöny, Beat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 

Thorne, Stephen H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 412 

Thornton, Charles A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Thornton, Mark. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 883, 899 

Thrasher, Adrian J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .268, 336, 759 

Throm, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 379 

Thyme, Summer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 

Tian, Jie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 

Tian, Jing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824 


184 


Tiemann, Katrin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 

Tiffany, Matthew R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 568 

Tikoo, Suresh K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216 

Tilly, Gaëlle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 

Tisdale, John F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117, 385 

Titze-de-Almeida, Ricardo . . . . . . . . . . . . . . . . . . . . . . . .570, 850, 851 

Tobari, Maiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 539 

Tobolt, Diane K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427 

Todo, Tomoki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796 

Toh, HanChong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Toh, Kazuko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305 

Toita, Riki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150, 172 

Tojyo, Masahiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237 

Tokumitsu, Ayako . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 315 

Tolar, Jakub . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 686 

Tolbot, D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .67, 836 

Tompkins, Joshua D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 550, 579 

Tong, Alex W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Tong, Chun-Rong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859 

Tonon, Giovanni. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 610 

Toole, Brian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533 

Torbett, Bruce E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 484 

Torikai, Hiroki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26, 903 

Toriyabe, Naoyuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 709 

Torok-Stord, Beverly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257 

Torrance, Chris . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 908 

Torres, Raul. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 431 

Toth, Karoly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518 

Tötterman, Thomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 502 

Tran, Chy-Anh T. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 586 

Tran, Nancy H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 546 

Treanor, Louise M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284 

Treger, Janet A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 

Treleaven, Christopher M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201 

Tremblay, Jacques P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 428, 471 

Trobridge, Grant D. . . . . . . . . . . . . . . . . . . . . . . . . . . 342, 344, 485, 637 

Trono, Didier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 267, 876 

Trujillo, Miguel A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58, 410, 799 

Trusov, Georgiy A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Tsai, Chih-Chien . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313, 325, 862, 924 

Tsai, Kuo-Shu. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 924 

Tsai, Richard K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 

Tschaika, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82, 87 

Tseng, Yu-Shan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 374 

Tsolaki, Eleftheria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Tsou, Wei-Ling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 846 

Tsukahara, Tomonori . . . . . . . . . . . . . . . . . . . . . . . . 188, 573, 696, 791 

Tsurumaki, Yuzuri. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796 

Tuddenham, E. G. D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 602 

Tuikue Ndam, N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Tung, Ching-Hsuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 308 

Turchiano, Giandomenico . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 

Turkki, Vesa. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 

Turner, Anne-Marie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 554 

Turner, Jeff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212 

Turnis, Meghan E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 

Turovets, Irina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 854 

Turovets, Nikolay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100, 854 

Tuschong, Laura M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 258, 346 

Twait, Erik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655 

Twisk, Jaap . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183 

Tykodi, Scott S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 

Tyler, Betty . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 

Tysome, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516 


U 

Uchibori, Ryosuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573, 791 

Uchida, Naoya. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117, 385 

Uchida, Satoshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 

Uchida, Yuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Uchino, Katsuhisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Uchino, Makoto . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Uchiyama, Makiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Uchiyama, Toru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 

Udagawa, Takeshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235 

Ueda, Yasuji . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523 

Ugarte, Magdalena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 

Ugolini, Matteo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 

Ulasov, Alexey V.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 

Ulasov, Ilya V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 683, 915 

Ulbrich, Karel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 416 

Ul-Hasan, Taihra B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128, 329 

Ulkoski, David . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Ulrich-Vinther, Michael . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 760 

Uludag, Hasan . . . . . . . . . . . . . . . . . . . . . . . . . . .62, 155, 162, 534, 810 

Umemoto, Yoshiaki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443 

Un, Keita . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430 

Underwood, Mark A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286 

Ungefroren, Hendric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 507 

Unger, G. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .67, 836 

Unger, Gretchen M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427 

Ungerechts, Guy . . . . . . . . . . . . . . . . . . . . . . . 514, 515, 521, 528, 798 

Unzu, Carmen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 184 

Urabe, Masashi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188, 573, 696, 791 

Urata, Yasuo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797, 800 

Urban, Nicole . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 815 

Urdahl, Kevin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 491 

Usas, Arvydas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373 

Utoh, Rie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190 

V 

Vaena, Daniel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 834 

Vago, Luca . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605 

Valdmanis, Paul N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 

Valero-Lapchik, Valderez Bastos. . . . . . . . . . . . . . . . . . . . . . . . . . . . 446 

Valles-Ayoub, Yadira . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 774


Van Craeyveld, Eline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737 

van Deel, Elza E. D.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713 

van der Loo, Johannes C. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613 

van der Valk, Marissa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 671 

van Deventer, Sander. . . . . . . . . . . . . . . . . . . . . . . . 562, 847, 564, 566 

van Dongen, Jacques J. M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 

van Heiningen, Sandra H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765 

Van Hoeven, N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

van Logtenstein, Richard . . . . . . . . . . . . . . . . . . . . . . . . .562, 847, 564 

van Ommen, Gert-Jan B.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 765 

van Rensburg, Ruan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .578, 689, 852 

van Til, Niek N. P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 252, 254, 713, 715 

Van Vliet, Kim. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329 

Vandenberghe, Luk H. . . . . . . . . . . . . . . . . . . . . . . . 196, 292, 326, 333 

Vandermeulen, Gaëlle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 695 

Vanier, Marie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Vasseur, Virginie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 293 

Velasquez, Fernando . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642 

Venditti, Charles P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 452, 453 

Ventura-Gallegos, JL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 920 

Vera, Juan F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .503, 513, 591 

Verchere, C. Bruce . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 334, 335 

Verfas, Patricia M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 747 

Verhoeyen, Els. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 876, 893 

Verrall, Ronald. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 182 

Versteeg, Henk K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 450 

Vetrini, Francesco . . . . . . . . . . . . . . . . . . . . . . 147, 277, 414, 419, 454 

Vets, Sofie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486 

Vettor, Roberto. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 657 

Viale, Diego L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 238 

Vickers, Selwyn M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 146, 673 

Vickers, Selwyn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .58, 525 

Viecelli, Hiu Man . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557 

Vijayan, Aneesh . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 916 

Vile, Richard G. . . . . . . . . . . . . . . . . . . . . . . . . . 358, 361, 775, 780, 891 

Villa, Anna. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 254, 604 

Villegas-C, Hilda . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 886, 887, 894, 895 

Villemejane, Julien . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 703 

Vin, C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Vincent, Justin M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694 

Vincent, Karen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 380 

Vinod, Sharma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629 

Viollet, Laurence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 768 

Viornery, Armelle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 589 

Visel, M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 872 

Visser, Trudi T. P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .252, 254, 713 

Viwami, F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 

Vlassov, Sasha . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 849 

Vleck, Jan P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 596 

Vogel, Ashley. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Vogler, Carole . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 717 

Vogt, Thomas F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Voigtlander, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 413, 679 

Voit, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51, 72, 661 

Volin, Michael V. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 751 

Volpin, Monica . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 607, 610 

Volz, Tassilo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

von Euler, Henrik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 502 

von Kalle, Christof . . . . . . . . . . . . .32, 42, 43, 46, 123, 223, 264, 269, 

. . . . . . . . . . . . 343, 347, 383, 389, 514, 521, 607, 610, 611, 632, 798 

von Laer, Dorothee. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 486, 641 

von Messling, Veronika . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515 

Voss, Ralf-Holger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221 

Vosters, Jelle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 831 

Voutila, Jon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 559 

Vozza-Brown, Laura A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445 

W 

Waddington, Simon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .46, 253 

Wadhwa, Renu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527 

Wadsworth, Samuel C. . . . . . . . . . . . . . . . . . . . . . . . . . . .380, 656, 664 

Wagemaker, Gerard G.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713 

Wagemaker, Gerard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .252, 254, 715 

Waks, Tova . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 

Waldmann, Thomas A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 

Walker, Christopher M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 

Walker, Jon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24, 79 

Walker, Sherry M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 833 

Wallace, Lindsay M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .75, 467 

Wallraven, Gladice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Walsh, Christopher E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134 

Walsh, Colin L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 565 

Walters, Glenn. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 341 

Wan, Limin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 700 

Wandless, Tom . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301 

Wang, Bing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .96, 367, 476, 758, 769 

Wang, Bo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

Wang, Chien-Yuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 924 

Wang, Chi-Hsien . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468, 766 

Wang, Daren . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 

Wang, Feng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824 

Wang, Gui-qiang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 213 

Wang, Hao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 

Wang, Hexiao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529 

Wang, Hong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 261 

Wang, Hongjie . . . . . . . . . . . . . . . . . . . . . . . . . .2, 18, 78, 135, 497, 689 

Wang, Hongmei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .345, 571, 833 

Wang, Jianbin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 484, 632 

Wang, Jiesheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178 

Wang, Jing-Bo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859 

Wang, Jinjin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 438, 700 

Wang, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 321 

Wang, Jun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844 

Wang, Lan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 821 

Wang, Lili . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186, 340 

Wang, Lisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357, 496 


186 


Wang, P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 

Wang, Peirong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120, 474 

Wang, Pengju . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516 

Wang, Peter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 

Wang, Pin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132, 219, 387, 492 

Wang, Qiang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 333 

Wang, Qizhao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 848, 923 

Wang, Ran . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437, 700 

Wang, Shaoying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 845 

Wang, Shelley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 598 

Wang, Shengdian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516 

Wang, Sin-Ting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 584 

Wang, Wenjing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218, 391 

Wang, Xiao Tian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 773 

Wang, Xiaoyin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Wang, Xiuli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 

Wang, Xiuyan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30, 230, 263 

Wang, Xu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 438 

Wang, Xuefeng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 828 

Wang, Yaohe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516, 529 

Wang, Yifeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 792 

Wang, Ying-Jiin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 924 

Wang, Yuanzhi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218 

Wang, Yulei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561 

Wang, Yupeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 

Wang, Yuqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 898 

Wang, Zejing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 

Wang, Zhongya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187, 463 

Ward, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 450 

Ward, Peter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134 

Warlich, Michael. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572 

Warren, Edus H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 

Washington, Kareem N. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 385 

Wasielewska, Teresa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 

Wasserfall, Clive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 669 

Wasserman, Wyeth W. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 744 

Watanabe, Atsushi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 451 

Watanabe, Ayumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222 

Watanabe, Natsumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 190 

Watanabe, Yoshihiko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 812 

Watchko, Jon F.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74 

Watson, Gordon. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461 

Watts, Ashlee E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 316 

Watts, Korashon L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372, 865 

Weaver, Eric A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8, 209, 488 

Webby, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209 

Weber, Helga L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 519 

Weber, Kristoffer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 572, 641 

Weber, Michel. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 207 

Weber, Thomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 398, 668 

Wee, Sunmee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 283, 652 

Wei, Wei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866 

Weichert, Wendy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 374 

Weigel-Van Aken, Kirsten A. K. . . . . . . . . . . . . . . . . . . . . . . . . . . . 1, 327 

Weikert, S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82 

Weinberg, Marco S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208, 556 

Weiner, David B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22, 504 

Weinzierl, Irina . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482 

Weismann, Cara M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 745 

Weissleder, Ralph. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303 

Weith, E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82, 87 

Welikson, Robert E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 

Wellman, Jennifer M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 600 

Wels, Winfried S.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221 

Wels, Winfried . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27, 496 

Welsh, David A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Wen, Zhiping. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555 

Wenger, David A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 720 

Wensel, Theodore G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Wentworth, Bruce M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Wesselschmidt, Robin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 579, 864 

West, Jennifer L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 666 

West, Richard A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 

West, Richard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 854 

Westberg, Sara . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 502 

Westermann, Jürgen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506 

Wheeler, Thurman M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 

Wherley, Jennifer P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 786 

White, Gary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 664 

Wicki, Jacqueline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 466 

Widdowson, Peter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 750 

Wiederholt, Kristin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445, 849 

Wielgosz, Matthew. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256 

Wijaya, Cori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735 

Wilkinson, Fiona L.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336, 716 

Wilkinson, Leslie. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 838 

Williams, David J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 450 

Williams, Dewight R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4 

Williams, James A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694 

Williams, Nathaniel P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 257 

Williard, Deborah. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655 

Wilson, James M. . . . . . . . . . . . . . . .19, 102, 108, 185, 186, 196, 214, 

. . . . . . . . . . . . . . . . . . . . . . . . . . 291, 292, 326, 333, 340, 545, 621, 874 

Wilson, John H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Wilson, John . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 591 

Wilson, Katherine M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165 

Wilson, Matthew H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13, 15 

Wilson, Steven P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 749 

Wininger, Fred A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 870 

Winkler, Thomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 

Winn, Michelle P. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 339 

Wirth, Thomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249, 816 



Wittig, B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82, 87 

Wittig, Burghardt . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 506, 507 

Witting, Scott R. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 889 

Wohleb, Eric. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362 

Wohlfahrt, Martin E. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865 

Wojton, Jeffrey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 362 

Wold, William S. M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518 

Wolfe, John H.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 618 

Wolfe, Thomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 671 

Woller, Norman . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 790 

Wong, ChingLam W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 

Wong, Han Hsi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529 

Wong, Jr., K. K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128 

Wong, K. K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329 

Wong, Shirley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 116 

Wong, Suet P.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 751 

Wong, Sunnie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 

Wongsrikeao, Pimprapar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 

Wongthida, Phonphimon . . . . . . . . . . . . . . . . . . . . . . . .358, 361, 780 

Woodard, Lauren E.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 

Worgall, Stefan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 210, 490 

Worth, Anna . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 513 

Wraith, J. Ed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336, 716 

Wright, Christine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 351 

Wright, J. Fraser . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193, 587, 403, 600 

Wu, Anna M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609 

Wu, Bo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 567 

Wu, Chih-Hsien. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 547 

Wu, Chuanfeng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 

Wu, Hongju . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 

Wu, Jingbo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391 

Wu, Joseph C. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 368 

Wu, Lily . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145 

Wu, Lingqian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697, 698 

Wu, Meiting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 741 

Wu, Robert A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 344 

Wu, Rui-Lin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 864 

Wu, Sheng Hua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 322 

Wu, Susan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .718, 719, 726 

Wu, Tong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859 

Wu, Wei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 672 

Wu, Xiaoping. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366 

Wulffraat, Nico M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 715 

Wynn, Rob . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 716 

Wynn, Robert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336 

X 

Xiang, Yiwen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1, 327 

Xiao, Bin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 468 

Xiao, Di. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 697 

Xiao, Dong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391 

Xiao, Juan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193 

Xiao, Liang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219 

Xiao, Liying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 244 

Xiao, Ping-Jie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395 

Xiao, Ru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 196 

Xiao, Weidong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 247, 848 

Xiao, Xiao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52, 468, 766 

Xie, Dan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Xie, Jianjun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 

Xie, Jun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400, 404, 555, 621 

Xie, Qing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 555 

Xie, Yiming . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 609 

Xing, James . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318 

Xiong, Weidong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 509, 784, 789 

Xiong, Yang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 

Xu, Lei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 766 

Xu, Mei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120 

Xu, Peng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 318 

Xu, Ruian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .247, 848, 923 

Xu, Yaqin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 210 

Xu, Zhili . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 

Xue, Jin-feng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824 

Xue, Jing-lun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .437, 438, 700 

Xue, Yuan-Yuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437 

Y 

Yablonka-Reuveni, Zipora . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 475 

Yagi, Hiroya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 188 

Yagiz, Kader . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59, 787, 788 

Yaiw, Koon-Chu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515 

Yamada, Suguru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Yamada, Yuma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444 

Yamaguchi, Saori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97, 861, 925 

Yamaguchi, Tomoko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 682 

Yamamoto, Masato. . . . . . . . 58, 146, 241, 525, 673, 674, 799, 911 

Yamamoto, Motoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 723 

Yamamura, Kazuo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .520, 526, 803 

Yamanaka, Makako. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282 

Yamaoka, Tetsuji. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181, 581 

Yamasaki, Satoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 673 

Yamashita, Fumiyoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . .319, 430, 443 

Yamashita, Satoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 770 

Yamauchi, Jun. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 835 

Yamauchi, Suguru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Yamazaki, Satoshi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312 

Yamazaki, Tomohiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 440 

Yammine, Miriam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 928 

Yan, Jian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 

Yan, Ziying . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 270, 660 

Yanay, Ofer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 

Yáñez-Muñoz, Rafael J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 268 

Yang, Baocheng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 930 

Yang, BC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 931 

Yang, Hsiao-Bai. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 924 

Yang, Hsueh-Ying L. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 741 


188 


Yang, Lili . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 219, 492 

Yang, Ping. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910 

Yang, Qing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 758, 769 

Yang, Shan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 282, 805 

Yang, Yanu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Yang, Yu-Lin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Yang, Zih-Han . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 

Yannaki, Evangelia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Yano, Shuya . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797, 800 

Yano, Tokujiro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523 

Yao, Gang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 244 

Yao, Hong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 819 

Yao, Xiaoying. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 689 

Yarde, Danielle N.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 802 

Yardeni, Tal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457 

Yasui, Hiroyuki. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 809 

Yasukawa, Masaki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777 

Yasumura, Eduardo G. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 742 

Yasuzaki, Yukari. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444 

Yawata, Toshio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248 

Ye, B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 896 

Ye, Jingjing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 579 

Ye, Lin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 464 

Ye, Peiqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 294, 828 

Ye, Xianlin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 930 

Ye, XL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 931 

Yeagy, Brian A.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 712 

Yeghiazarians, Yerem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Yen, Tzu-Chen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 

Yew, Tu-Lai . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .313, 862, 924 

Yiangou, Minas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 

Ying, Lee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461 

Ylä-Herttuala, Seppo . . . . . . . . . . . . . . . . . . . . . . . . . . . . .109, 249, 816 

Ylösmäki, Erkko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 684 

Ylostalo, Joni H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 

Yockman, James W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 159 

Yokoi, Takayuki . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714, 721 

Yokoo, Takeshi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 705 

Yokota, Takanori. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88, 92, 553 

Yokota, Toshifumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 558 

Yokota, Yosuke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 222, 233 

Yonemitsu, Yoshikazu . . . . . . . . . . . . . . . . . . . . . . . . . . . .103, 523, 813 

Yong, Diao . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 923 

Yoo, Byoung Kwon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 242 

Yoo, Ji Young . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421 

Yoon, A.-Rum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 527 

Yoon, Chang S. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 710 

Yoon, Sujin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297 

Yoshida, Eileen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 860 

Yoshida, Kie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .92, 553 

Yoshida, Kumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .103, 523, 813 

Yoshida, Mitsuru . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 430 

Yoshida, Ryosuke. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 797, 800 

Yoshida, Teruhiko. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235 

Yoshida, Tsukihisa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 523 

Yoshihara, Chieko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152, 237 

Yoshioka, Hirofumi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 777 

Yoshitomi, Toru. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305 

Younan, Patrick. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485 

Young, Brittany A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 518 

Young, Joseph K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 779 

Yu, Kenneth K.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 494 

Yu, Kyeong-Nam . . . . . . . . . . . . . . . . . . . . . . . . . . . . 246, 909, 926, 929 

Yu, Lianbo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 867 

Yu, Ping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81 

Yu, William . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 415 

Yu, Yang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 505 

Yu, Yong A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Yuan, Jinyun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 484 

Yuan, Ming. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 529 

Yuan, Zuobiao. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 655 

Yudovich, David. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 422 

Yue, Yang-bo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437 

Yue, Yongping. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309, 481 

Yuen, Carrie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 

Yugeta, Naoko . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 764 

Yumul, Roma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78, 226, 497 

Yun, Chae-Ok . . . . . . . . . . . . . . . . . . . . . .140, 145, 421, 527, 685, 806 

Yun, In Sik . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140 

Yun, Tae Jin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140 

Yun, Ui Jeong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 817 

Yvon, Eric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 913 


Z 

Zabner, Joseph. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399, 654 

Zacchigna, Serena. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 532, 728 

Zacharias, Jeana. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 822 

Zadmehr, Ali . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 

Zadorozhny, Victoria. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 814 

Zaia, John A. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99, 314, 586 

Zaiss, Anne K. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 142 

Zamore, Phillip D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .47, 555 

Zanetti, Gianluigi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606, 611 

Zanzonico, Pat B. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Zaoui, Karim . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 514, 798 

Zaraspe, Kimberly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337 

Zegura, Bojana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 448 

Zeh, Herbert J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 599 

Zelenaia, Olga. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 403 

Zeller, W. Jens . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 

Zeng, Yue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 

Zentella- D, Alejandro . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 887 

Zentella-Dehesa, A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 920 

Zentilin, Lorena . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .532, 614, 728 

Zerah, Michel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 195 

Zerfas, Patricia M.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453


Zhang, Ai-Hong (Allan) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 830 

Zhang, Aiwu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Zhang, Chun . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 919 

Zhang, Guisheng. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 627, 705 

Zhang, Hongwei . . . . . . . . . . . . . . . . . . . . . . . . . . . . 404, 555, 649, 827 

Zhang, Hui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218 

Zhang, Jane. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 493 

Zhang, Jian-Ping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 859 

Zhang, Jianqing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 250 

Zhang, Jiuli. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Zhang, Lei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 498 

Zhang, Ling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 218, 391 

Zhang, Ping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289 

Zhang, Qian. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 640 

Zhang, Steve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 648 

Zhang, Ting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 418 

Zhang, Weibing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 376 

Zhang, Yadong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 688 

Zhang, Yan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 730 

Zhang, Yu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .363, 400, 404 

Zhang, Yuan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 

Zhang, Yue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 677 

Zhang, Yulong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275 

Zhang, Zhenwei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 675 

Zhang, Zhixiang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 866 

Zhang, Zhong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 751 

Zhao, Huifen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 346 

Zhao, Huiren . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 671 

Zhao, Li . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 856 

Zhao, Xin. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191 

Zheng, Changyu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 642, 657 

Zheng, Dexian . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537 

Zheng, Guopei . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 

Zheng, Hui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .52, 468 

Zheng, X . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 931 

Zheng, X. Long. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193 

Zheng, Xin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 930 

Zheng, Yi. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 735 

Zheng, Zhaohui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266 

Zhili, Zheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231 

Zhong, Bonan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 865 

Zhong, Li. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 400, 404, 555, 621, 827 

Zhong, Wen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 811 

Zhou, Dongbing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 792 

Zhou, Dongming. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680 

Zhou, Fei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 824 

Zhou, Heather H. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731 

Zhou, Jason . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 910 

Zhou, Jiehua . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 

Zhou, Jinyuan . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 

Zhou, Qinghui . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 

Zhou, Shangzhen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .49, 403 

Zhou, Sheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259, 284 

Zhou, Xiangyang. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 680 

Zhou, Xianzheng . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 255 

Zhou, Xiaohuai. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 548 

Zhou, Yuanyue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 

Zhu, Jie . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272 

Zhu, Liwei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 792, 866 

Zhu, Tsugumine. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 

Zhu, Weigang . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 930 

Zhu, Wen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 210, 490 

Zhu, WG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 931 

Ziebermayr, R.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 

Zilberman, Yoram . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .320, 370, 761 

Ziliotto, Raul. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588 

Zilla, Peter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 629 

Zillmer, Allen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 567 

Zogovic-Kapsalis, Tatjana . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 

Zolotukhin, Irene. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 663 

Zolotukhin, Sergei. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .330, 332, 405 

Zoltick, Philip W.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 

Zou, Jizhong . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345 

Zsebo, Krisztina M. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601 

Zuber, Guy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180 

Zucchelli, Eleonora . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 588 

Zwiebel, J . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 891 

Zwipp, Hans. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469, 482 


190 

Notes 


Notes 


192 

Notes 


Announcing the American 

Society of Gene & Cell 

Therapy’s 2011 Strategic Plan! 

In June 2010, the American Society of Gene & Cell Therapy (ASGCT) began a comprehensive 

strategic planning effort to chart the direction and future course of ASGCT. The strategic plan, 

adopted in April 2011, includes input from the ASGCT membership, key opinion leaders in gene 

and cell therapy, the Society leadership, and Society staff members. 

The ASGCT Board of Directors is excited to reveal the 2011 ASGCT Strategic Plan: 

ASGCT’S MISSION IS TO: 

Advance knowledge, awareness, and education leading to the discovery and clinical application 

of genetic and cellular therapies to alleviate human disease. 

ASGCT’S STRATEGIC VISION IS TO BE A: 

Catalyst for bringing together scientists, physicians, patient advocates, and other stakeholders to 

transform the practice of medicine by incorporating the use of genetic and cellular therapies to 

control and cure human disease. 

OVER THE NEXT FIVE YEARS, ASGCT’S GOALS ARE THE FOLLOWING: 

Goal 1: Expand and engage a diverse membership that increases ASGCT’s impact and 

effectiveness. 

Goal 2: Increase and diversify revenue and maintain appropriate reserves to support anticipated 

growth of mission aligned programs and services. 

Goal 3: Expand ASGCT’s preeminence by advancing novel nucleic acid, cell and tissue therapies. 

Goal 4: Expand public, governmental and industry support for nucleic acid, gene, cell and tissue 

therapies. 

Goal 5: Offer mission aligned, financially viable programs and services that will best serve our 

members and stakeholders and increase their impact in the field. 

Visit the ASGCT Exhibit 

Booth for more information 

on the new strategic plan!

Photo Credit: National Institutes of Health/Department 

of Health and Human Services 

Bethesda, 

Maryland 

Philadelphia, 

Pennsylvania 

Save-the-Date 

ASGCT 2011-2012 Programs 

NIH Gene Therapy 

Symposium 

September 26-27, 2011 

Natcher Conference Facility, NIH 

Bethesda, Maryland, USA 

ASGCT 15th 

Annual Meeting 

May 16-20, 2012 

Philadelphia Convention Center 

Philadelphia, Pennsylvania, USA 

For more information or to register, visit the ASGCT website at www.asgct.org. 

ASGCT-0311-066

Final Program - American Society of Gene & Cell Therapy

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?