GULFTENE C16-18 ISOMERISED OLEFINS - NICNAS
GULFTENE C16-18 ISOMERISED OLEFINS - NICNAS
GULFTENE C16-18 ISOMERISED OLEFINS - NICNAS
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Draize scores of non irrigated eyes:<br />
Time after instillation<br />
Animal 24 hours 48 hours 72 hours<br />
Conjunctiva r c d r c d r c d<br />
1 1 0 0 0 0 0 0 0 0<br />
2 1 0 0 0 0 0 0 0 0<br />
3 0 0 0 0 0 0 1 0 0<br />
4 1 0 0 1 0 0 1 0 0<br />
5 0 0 0 1 0 0 1 0 0<br />
6 0 0 0 0 0 0 1 0 0<br />
Cornea All individual scores were zero<br />
Iris All individual scores were zero<br />
1 see Attachment 1 for Draize scales<br />
r = redness c = chemosis d = discharge.<br />
Ocular effects: Transient conjunctival redness;<br />
No iridial or conjunctival effects noted (all individual scores<br />
were zero).<br />
Mean group score<br />
(24, 48 & 72 hour<br />
observation):<br />
Corneal opacity: 0.0<br />
Iridial inflammation: 0.0<br />
Conjunctival redness: 0.4<br />
Conjunctival chemosis: 0.0<br />
Result: C12-<strong>C16</strong> Alpha Olefins were slightly irritating to the eyes of<br />
rabbits<br />
FULL PUBLIC REPORT 26 April 2000<br />
NA/713 Page 51 of 100
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