GULFTENE C16-18 ISOMERISED OLEFINS - NICNAS
GULFTENE C16-18 ISOMERISED OLEFINS - NICNAS
GULFTENE C16-18 ISOMERISED OLEFINS - NICNAS
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are appropriate for the <strong>C16</strong>-C<strong>18</strong> congener, and indicate significant potential for bioconcentration.<br />
The BCF for a compound may also be estimated from Log Pow using Quantitative Structure<br />
Activity Relationships (QSARs). (Lyman 1982) give a number of QSARs for this purpose<br />
but equation 5-2 is recommended for general estimation of the BCF from Log Pow. This<br />
equation is –<br />
Log BCF = 0.76 x Log Pow – 0.23,<br />
and assuming a Log Pow of 7, estimates Log BCF at 5.1 (BCF = 125 900), which agrees well<br />
with the experimental data above.<br />
(Connell 1990) indicates that compounds with a molecular weight around 350 and a Log Pow<br />
around 6 may have high potential for bioaccumulation. In the present case the molecular<br />
weight is 190-280, while Log Pow appears to be between 6 and 8. Connell (1990) also<br />
remarks that the potential for bioaccumulation peaks when water solubility is around 2 x 10 -6<br />
mole/L, and drops off on either side of this value. The water solubility of Gulftene 16-<strong>18</strong> is<br />
estimated to be less than <strong>18</strong> µg/L (less than 10 -7 mole/L) and consequently while the modest<br />
molecular weight and large value for Log Pow indicate large potential for bioaccumulation,<br />
this may be mitigated by the low water solubility.<br />
It should be remarked here that the extent of bioaccumulation is also dependent on the rate of<br />
biodegradation, and while it is probable that after release into marine sediments the new<br />
material will be susceptible to anaerobic degradation, the rate of these processes is uncertain.<br />
Consequently, it must be concluded that the probability for bioaccumulation in marine<br />
organisms may be high.<br />
FULL PUBLIC REPORT 26 April 2000<br />
NA/713 Page 16 of 100