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A new vision to understanding medicine 

Handbook of 

Clinical Gender 

Medicine 

CACGGTATCCAATGATAAGCATGATAAG 

Editors 

Karin Schenck-Gustafsson 

Paula R. DeCola 

Donald W. Pfaff 

David S. Pisetsky 

Gender medicine is an important new field in health and disease. It is derived 

from top-quality research and encompasses the biological and social determinants 

that underlie the susceptibility to disease and its consequences. In the future, 

consideration of the role of gender will undoubtedly become an integral feature of 

all research and clinical care. 

Defining the role of gender in medicine requires a broad perspective on biology and 

diverse skills in biomedical and social sciences. When these scientific disciplines 

come together, a revolution in medical care is in the making. Covering twelve 

different areas of medicine, the practical and useful ‘Handbook of Clinical Gender 

Medicine’ provides up-to-date information on the role of gender in the clinical 

presentation, diagnosis, and management of a wide range of common diseases. 

The contributing authors of this handbook are all experts who, in well-referenced 

chapters, cogently and concisely explain how incorporation of gender issues into 

research can affect the medical understanding and treatment of heart disease, 

osteoporosis, arthritis, pain, violence, and malaria among other conditions. 

This intriguing and unique medical textbook provides readers with a valuable new 

perspective to understand biology and incorporate gender issues into the 

different branches of medicine. 

www.karger.com/Gender_Medicine 

ACGGTATCCAATGAT 

ATAAGCATCACGGTATCCAATGATAAGCATGATAAGC TCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCAT 

GATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGC TCACGGTATCCAATGATAAGCATCAC 

GGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGG 

TATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATA 

AGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATA 

AGCATCACGGTATCCAATGATAAGCATGATAAGCGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCAC 

GGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCCACGGTATCCAATGATAAGCATCACGGTATCCAAT 

GATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATA 

AGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATA 

AGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGG 

TATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATC 

CAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATA 



AGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCAGCATGATAAGCTCACGG 




AGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGTCACGGTATCCAATGATAAGCATCACGG 

TATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCCACGGTATC 


AGCATGATAAGCCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATA 










AGCATGATAAGCGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCAC 

GGTATCCAATGATAAGCATGATAAGCCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGG 












AGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGTCACGGTATCCAATGATA 


AGCCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGG 





AGCATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCAT 

GATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCAC 

GGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGG 



AGCATCACGGTATCCAATGATAAGCATGATAAGCGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCAC 

GGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCCACGGTATCCAATGATAAGCATCACGGTATCCAAT 

GATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATA 

AGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGAGTATCCAATGATAAGCATGATA 






AGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCTCACGGTATCAGCATGATAAGCTCACGG 




AGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGTCACGGTATCCAATGATAAGCATCACGG 

TATCCAATGATAAGCATGATAAGCTCACGGTATCCAATGATAAGCATCACGGTATCCAATGATAAGCATGATAAGCCACGGTATC 

CAATGATAAGCATCACGGTATCCAATGATAAGCAT 

ACGGTATCCAATGATAAGCATGATAAG 

ACGGTATCCAATGATAAGCATGATAAG 

CAATGATAAGCATCACGGTATCCAATGATA 

TGCATCACGGTATC 

Handbook of 

Clinical Gender 

Medicine 

Editors 

Karin Schenck-Gustafsson 

Paula R. DeCola 

Donald W. Pfaff 

David S. Pisetsky 

AGCATCACGGTATCCAATGATAAGCATGATAAG 

Handbook of Clinical Gender Medicine 

Editors: Schenck-Gustafsson, K. (Stockholm); DeCola, P.R.; 

Pfaff, D.W. (New York, N.Y.); Pisetsky, D.S. (Durham, N.C.) 

XVI + 522 p., 62 fig., 4 in color, 63 tab., soft cover, 2012 

CHF 69.– / EUR 51.– / USD 69.00 

Prices subject to change 

EUR price for Germany, USD price for USA only 

ISBN 978–3–8055–9929–0 

e-ISBN 978–3–8055–9930–6 

TATCCAATGATAAGCCGG 

Fields of Interest 

General Medicine; Internal Medicine; Cardiovascular System, 

Geriatrics, Immunology, Infectious Diseases, Neurology, Metabolism, 

Nephrology, Oncology, Pharmacology, Psychology, Psychiatry, 

Social Medicine, Urology 

AGCATCACGGTATCCAATGATA 

ACGGTATCCAATGAT

CACGGTATCCAATGATAAGCATGATAAG 

ACGGTATCCAATGAT 

Order Form 

Contents 

• Foreword: Wainer, J.; Wainer, Z. 

• Preface: Schenck-Gustafsson, K. 

Introduction 

• Gender Matters: Wainer, J.; Wainer, Z. 

• Biological Sex and the Genome: What Makes Us 

Ourselves? Legato, M.J. 

Social and Biological Determinants in Health 

and Disease (DeCola, P.R.; Schober, J.M.) 

• Gender Effects on Health and Healthcare: 

DeCola, P.R. 

• A Global War against Baby Girls: Sex-Selective 

Abortion Becomes a Worldwide Practice: 

Eberstadt, N.N. 

• Fetal Programming: Glezerman, M. 

• Ambiguous Genitalia: Mouriquand, P.D.E.; 

Schober, J.M. 

Central Nervous System and Clinical 

Applications (Pfaff, D.W.) 

• Chronic Stress and Allostatic Load: Juster, R.-P.; 

Lupien, S.J. 

• Autism: Knickmeyer, R.; Baron-Cohen, S. 

• Depression: Rubinow, D.R.; Craft, C.D. 

• Violence: Adaptive Regulated Aggression 

Contrasted with Violence Against Women: 

Kreinin, T.; Esteva, C.G.M.; Pfaff, D.W.; Lusweti, S.; 

Shauri, H.S. 

Neurology (Olsson, T.) 

• Parkinson’s Disease: af Edholm, K.; 

Svenningsson, P. 

• Stroke: von Euler, M. 

• Multiple Sclerosis: Olsson, T. 

• Epilepsy: Tomson, T.; Sveinsson, O. 

• Migraine and Other Headaches: Waldenlind, E. 

Please send 

copy/ies: ■ Handbook of 

Clinical Gender Medicine 

CHF 69.– / EUR 51.– / USD 69.00 

ISBN 978–3–8055–9929–0 

For easy ordering or further information about the series 

log on to: www.karger.com/gender_medicine 

Payment 

Postage and handling free with prepayment 

Please charge this order to my credit card 

■ American Express ■ Diners 

■ Visa ■ MasterCard 

Card No.: 

Exp. date: 

CVV/CVC: 

■ Check enclosed ■ Please bill me 

Pain (Murphy, A.Z.) 

• Fibromyalgia: Kosek, E. 

• Temporomandibular Joint Disorders: Lim, P.F.; 

Maixner, W.; Khan, A.A. 

• Irritable Bowel Syndrome: Kilpatrick, L.A.; 

Tillisch, K. 

• Pain and Analgesia: Loyd, D.R.; Murphy, A.Z. 

Circulation (Schenck-Gustafsson, K.) 

• Coronary Heart Disease: Schenck-Gustafsson, K. 

• Coronary Heart Disease and Female Sex 

Hormones: Schenck-Gustafsson, K. 

• Heart Failure: Kühn Madsen, B. 

• Arrhythmias: Insulander, P.; Vallin, H. 

Cancer (Gustafsson, J.-Å. ) 

• Cancer: Ernberg, I. 

• Three Nuclear Receptors Involved in Gender- 

Related Proliferative Diseases (ER-β, LXR-α, and 

LXR-β): Warner, M.; Gustafsson, J.-Å. 

Metabolic Disease (Werner, S.) 

• Type 1 Diabetes: Ma, R.C.W.; Chan, J.C.N. 

• Type 2 Diabetes: Chamnan, P.; Ma, R.C.W.; 

Chan, J.C.N. 

• Obesity: Rössner, S.M.; Rössner, S. 

• Pituitary and Thyroid Diseases: Werner, S. 

• Diseases of Calcium Metabolism and Bone 

Metabolic Disorders: Thorén, M. 

• Adrenal Disorders, Female Androgen Deficiency, 

Hirsutism, and Endocrine Hypertension: 

Thorén, M. 

• Transsexualism: Dhejne, C.; Arver, S. 

Name/Address (please print): 

E-Mail: 

Date: 

Signature: 

To be ordered through: 

Autoimmune, Inflammatory, and 

Musculoskeletal Disease (Pisetsky, D.S. ) 

• Systemic Lupus Erythematosus: Shiraishi, M.; 

Clowse, M. 

• Rheumatoid Arthritis: Lesuis, N.; 

van Vollenhoven, R.F. 

• Osteoarthritis: Sowers, M.; 

Karvonen-Gutierrez, C.A. 

• Spondyloarthritis: Eder, L.; Gladman, D.D. 

• Gout: Hershfield, M.S. 

Infectious Diseases (Britton, S.) 

• HIV Infection: Tozzi, V. 

• Malaria: Färnert, A.; Kulane, A. 

• Measles Infection: Aaby, P. 

• Tuberculosis: Ekéus Thorson, A. 

Urology, Sexual Dysfunction, and Nephrology 

(Arver, S.) 

• Lower Urinary Tract Symptoms, Benign Prostatic 

Hyperplasia, and Overactive Bladder: Peeker, R. 

• Sexual Dysfunction in Women: Öberg, K. 

• Sexual Dysfunction in Men: Buvat, J. 

• Chronic Kidney Disease: Carrero, J.-J. 

Pharmaceutical Drugs (Parekh, A.) 

• Women in Clinical Drug Trials: United States Food 

and Drug Administration Update on Policies and 

Practices: Parekh, A. 

• Drug Disposition and Effect: Mattison Faye, A.C.; 

Mattison, D.R. 

Geriatrics (Herlitz, A.) 

• Aging in a Gendered Society: Social and Biological 

Determinants of Health in the Elderly Population: 

Parker, M.G. 

• Multimorbidity: Mangialasche, F.; Marengoni, A.; 

Kivipelto, M. 

• Dementia: Wang, H.-X.; Kivipelto, M. 

• Cognition: Herlitz, A.; Lovén, J. 

Author Index/Subject Index 

Orders can be placed at agencies, bookstores, directly with the 

publisher, or with any Karger distributor. 

S. Karger AG, P.O. Box, 4009 Basel (Switzerland), 

Fax +41 61 306 12 34, E-Mail orders@karger.ch 

USA: S. Karger Publishers, Inc., 26 West Avon Road, P.O. Box 529, 

Unionville, CT 06085 (USA), Toll free: 1-800-828-5479 

Germany: S. Karger GmbH, 79095 Freiburg 

France: Librairie Médi-Sciences, 75007 Paris 

Gulf Council Countries, Iran, Middle East, North Africa, Turkey: 

Trans Middle East Internat. Distribution Co. Ltd., KaSha, 

Amman 11621 (Jordan) 

Japan: Karger Japan, Inc., Tokyo 105-0012 

South East Asia, China and Taiwan: Karger Regional Office, 

Kuala Lumpur 50470 (Malaysia) 

For details and further representatives and agencies 

see www.karger.com/worldwide 

KP 12115 (55.05.12) Printed in Switzerland 

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