where sharp minds incubate - Mumbai Educational Trust

The Nest
where sharp minds incubate
MET INSTITUTE OF PHARMACY
A students’ council presentation
2007 - 2008

Our Faith
Knowledge can neither be stolen by a thief,
nor snatched by a king.
It is indivisible unlike ancestral property,
it never burdens the bearer,
it multiplies manifold when offered to others.
Knowledge is the supreme form of wealth.
Our Vision
To shape professionals, to conquer the present and the future challenges
to the socio economic fabric of our society, by institutionalising search,
development, research and dissemination of relevant knowledge
through structured learning systems.
Our Mission
To evolve, develop and deliver dynamic learning systems
to equip professionals with conscience and commitment
to excellence and courage to face business challenges.

What’s Inside
S.No. Contents Page No.
01 About MET 1
02 MET Institute Of Pharmacy 2
03 Message From The Trustees 3
04 The Director Speaks 4
05 From The Principal’s Desk 5
06 Our Dronacharyas 6
07 From The Cultural In-Charge 7
08 Editorial & The Council Talks 8
09 The Students’ Council 9
10 Campus News 11
11 Chutkule’ 18
12 Model Mentor 25
13 Poesy 26
14 We Mean Business! 31
15 Tit-Bits 42
16 Page 3 Glitterati 50
17 Non-Teaching Staff 52
18 The Victorious 53

1
About MET
At MET, we encourage students to push the
limits of their minds. Because, we believe,
that's what gives them the edge. Today, we
can say with pride that our students aren’t
just intelligent. They are sharp. Razor sharp.
Armed with experience and knowledge, the
MET faculty goes beyond the syllabus and
teaches the students life management.
Quick-thinking. Ingenious. Committed. The
faculty won’t leave the class till every
question has been answered, every doubt
erased.
If MET students are head and shoulders
above the rest, its because our faculty
spares no effort to sharpen the area
between their ears.
Just a stone's throw away from the Arabian Sea, is an institution that is creating waves. Because, it is quite
simply, a cut above the rest. The MET League of Colleges is a conglomerate of premiere educational
institutions, driven by a single minded focus on imparting quality education to make students sharp.
Established in 1989, with a mission to redefine the system of education, MET is a professionally managed,
multi disciplinary & multi faceted oasis of knowledge. Its premiere educational institutes conduct university
accredited and autonomous programmes. The grant of the ISO 9001:2000 certification is an
acknowledgment of the institution's capability to deliver professional education that meets the highest
standards of professionalism worldwide. All this, to help young professionals face the challenges of life. And
make their mark in the corporate world.
MUMBAI CAMPUS
Institute of Management
Institute of Mass Media
Asian Management Development Centre
Institute of Pharmacy
Institute of Medical Sciences
Institute of Information Technology
Institute of Computer Science
Institute of Distance Learning
Institute of Software Development & Research
Institute of Trichology
Institute of International Studies
Rishikul Vidyalaya
Knowledge Explorer - Publishing Division
NASHIK CAMPUS
Institute of Management
Institute of Pharmacy
Institute of Engineering
Institute of Technology - Polytechnic
Institute of Information Technology
Institute of Distance Learning

MET Institute of Pharmacy
The MET Institute of Pharmacy was established in the year 1993 with the two-year Diploma programme in
Pharmacy (D.Pharm.) recognised by the Directorate of Technical Education. The four-year Bachelor's
programme in Pharmacy (B.Pharm.) affiliated to the Mumbai University was started in the year 1994.
The MET IOP is approved by the Pharmacy Council of India, New Delhi.
The Institute pursues the philosophy of perpetual acquisition of knowledge. Apart from academic curriculum,
our policy has been to provide value based education and to expose the hidden potential of the students.
Our students have free access to the computer facilities and are provided with LCD projector in the class
room for their seminar presentation. Our aim is not to make the students mere job-seekers but to make them
the architects of their future.
Over the years, several distinction holders and University toppers have graduated from our institute.
Our students not only excel in academics but they have been champions at various cultural and sports
competitions. The thirteen batches of Diploma students have passed out with excellent results. Fourteenth
batch has already given their final exams, which was conducted by the MSBTE, Government of Maharashtra.
The average result each year is above 90%. Our alumni are doing us proud all over the globe by being
leaders in their choice of vocation.
2

3
Message From The Trustees
GIVING INDIA THE EDGE
There comes a time in the history of a nation when braving all odds it marches forward regardless of global
dominance. Powered by double digit growth of the industrial sector, 300 million middle class and 500 million
young hopefuls, our country is soon developing as the engine of growth of the world economy. Globally,
thought leaders hold a common view that India represents the aspirations of the world. Undoubtedly, the
educated English speaking, technology savvy youth will lead us to universal success.
With two million schools, five million teachers and associates with a million young professionals offering their
services to industry and business annually, the economy is poised ushering in a techno commercial revolution
in the country. But as the forces of globalisation bring in competition with accompanying cost and bottom line
pressures, we will soon be faced with the question of class vis à vis mass education. As the industry becomes
more competitive and as we try and reach out to the global markets, we will have to deliver world class quality
products and services all the time. Therefore, nurturing and developing high quality educational systems and
institutions will become the prime responsibility of all the stakeholders in education.
We believe that the golden age of India is with us and ahead of us and not behind us. At MET, through our
academia and pedagogy we seek to offer world class learning systems to the youth. Through a balanced mix
of academics and industry interaction, we train professionals who have not only contributed significantly to
the Indian industry but have reached beyond the shores of this country and sought global acclaim for our
efforts.
Today, India is emerging as a global super power. Not surprising, considering she has produced some of the
best minds in the world. In every field, Indians are making their mark in the international arena. At MET, in our
own small way, we are trying our best to add to the country's intellectual capital. By producing the next
generation of sharp minds. Who, we hope, will shape India's future. And lead her to greater heights.
MET is our humble contribution to the building of resurgent India poised to conquer the global economy.
Chhagan Bhujbal
Founder Chairman
Sunil Karve
Founder Trustee &
Vice Chairman
Pankaj Bhujbal
Trustee
Samir Bhujbal
Trustee

The Director Speaks
Dr. U. B. Hadkar
Director
When I look back at the past ten years that I have been with MET, there are many vignettes
that stand out. It has been a great ten years of pharmacy education. May the next ten
years be better than others.
Our students have been doing a marvelous job on the academic front. There have been
university toppers in the past 3 years. I take this opportunity to congratulate Mr. Mihir Shah
who was a university topper at the second year B. Pharm. held in May/ June 2007. Our
teachers are also engaged in research activities through out the year , our principal Dr.
Abha Doshi has presented a paper at the international seminar held at Amsterdam in
September 2006. Also Dr. Anand Shedge presented a paper in the international
conference held at Australia.
I am proud to state that our students have lifted the Rx sports trophy this year.
Dear students every day, life throws a million opportunities your way and we believe you
should make use of most of them. It is this belief that has made us an outstanding
institution of pharmacy.
There have been some changes in Pharmacy education in the past ten years. From the
yearly pattern we have shifted to the semester pattern. This year for the first year B.Pharm.
the semester examinations are being conducted at the institute level, although the
question papers are set by the University of Mumbai. There is increased load on our
teachers which they have accepted and are taking care to see that the students will adjust
quickly to this change over.
I wish to express my gratitude to our respected trustees Shri. Chhagan Bhujbal,
Shri. Pankaj Bhujbal for providing us the podium to seek and disseminate knowledge.
I am thankful to Mrs. Shefali Bhujbal, Mrs. Vishaka Bhujbal for their unstinted support.
Our special thanks to Mr. Irani for helping us in designing our magazine 'THE NEST.'
Dear students whatever role life gives you, play it big.
Regards,
Jai Hind!!!
4

5
From The Principal’s Desk
Dr. Abha Doshi
Principal (Degree)
Mr. S. D. Bhosale
Principal (Diploma)
We at MET, had an eventful 2007 and a great start for 2008.
Last year a university topper among our student and a good academic result made us proud .
This year began with lots of new activities. For the first time, MET IOP organized a one day
seminar on 'Emerging trends in Pharmacy.' It was a knowledge enriching experience and
the students and the faculty could also interact with the various speakers who are
renowned in the field of pharmacy.
Another thing in this year, was the three day educational tour to Goa; where in the third
year and the final year students visited pharmaceutical industries with US FDA approval.
For the students it was an eye opener where in they could practically see the
implementation of the theoretical aspects taught in their classes.
Our students also showcased their talents in the inter-collegiate Rx festival; and we are the
proud winners of the Rx sports trophy. Also we are the best in our cultural activities and
have won the Best Dance & runners up in cultural activities. I congratulate all the students
for winning the best college award and we are proud of you.
Someone rightly said that “SUCCESS IS 1% INSPIRATION & 99% PERSPIRATION.”
Persistent people begin their journey of success at the same point with others whose
journey ended in failure. Failure is success turned inside out and you have to strive hard till
you reach your goal ,and the success is yours . Winners are people who continually make
small corrections in their performance until they get exactly what they want.
So, dear students, go beyond the normal standards in performance. Dig deeper and put
in the extra effort, walk that extra mile and sure enough success will be yours.
Dear Students,
It gives me an immense pleasure to write this message for 'THE NEST' which is always a
good collection of different forms of informative literature. I wish all the best to editorial
committee members and hope this issue of the nest will also be an informative and a
memorable one.
Today the Indian healthcare system is undergoing a dramatic change. There is an
increase in the life expectancy and also disease burden which demands a growth in
healthcare services and patient needs.
In our country, pharmacist is the most accessible healthcare worker and can play a
responsible role in providing healthcare services at all levels.
With the growth in Indian healthcare there is an increase in the demand for the health
professionals which can provide high standards of services.
Therefore an expert, competent and motivated pharmacist is the need of the day. This will
help to change the perceived role of pharmacist from being a trader or shopkeeper to
that of a true healthcare professional.
All The Best

Our Dronacharyas
Degree
Standing (L to R): Dr. Rashmi Shrivastava, Ms. Bhavna Patel, Ms. Vrushali Keer,
Ms. Bharti Mal, Ms. Nikita Dhruv
Sitting (L to R): Ms. Sheeja Koliyote, Ms. Bhagyashree Joshi, Dr. U. B. Hadkar,
Dr. (Mrs.) Abha Doshi, Dr. Sonali Naik, Ms. Vijaya Patil, Ms. Radhika Raheja
(Not in Picture: Ms. Poonam Advani, Ms. Sagarika Gajbhiye)
Diploma
Standing (L to R): Ms. Abhilasha Sharma, Ms. Kiran Dube, Ms. Deepali Patil
Sitting (L to R ): Ms. Sushama Gokhale, Mr. S. D. Bhosale, Dr. U. B. Hadkar,
Ms. Neha Barfiwala (Not in Picture: Ms. Vaishali Malwankar)
6

7
From The Cultural In-Charge
th
It gives us great pleasure to present the 8 edition of The Nest. This year we celebrated most of the festivals on
symbolic basis. The motive behind it was to introduce to our youth our rich culture and heritage. It began with
'Dindi Yatra' (pilgrimage) on Aashadi Ekadashi followed by Mangalagauri function and Nagpanchami
celebration in the month of Shravan. We also celebrated Makar Sankranti by distributing Tilgul to all the
departments of MET.
Our students successfully balance the academic and extra-curricular activities. We feel very proud to have
the university topper from S.Y.B.Pharm. This year our students have won the RX sports trophy, The Best
College trophy, Dance trophy and runners up in Cultural events. We congratulate all those who have put in a
lot of hard work and efforts for this victory.
We express our gratitude to our trustees, Director, Principals, Faculty members and Non-teaching staff who
continuously helped us throughout various cultural events.
Last but not the least we are highly thankful to our students council who gave sweat to make each and every
event possible and successful. We also thank the students who extended their hands to help in all possible
ways. We would also like to thank Mrs. Kalyani Asgaonkar, Ex co-cultural incharge for her excellent cooperation
during her tenure.
- Cultural In-Charge
Dr. Sonali Naik
Ms. Sushama Gokhale

Editorial
Its celebration time! This is the time of the year when we look back and remember what we have conquered in
the academic year. It's been a great run for the students of MET with the progress chart going straight out of
the roof. New trophies, new achievements it always seems that it can't get any better. But every year the
students slip a fast one and somehow make it much better.
The Nest is a mirror. It reflects the persistence, hard work and vigor. It reminds us that this is what we are
capable of and of course aids us in showing off!
As for what we have not been able to achieve, 'It's not a dream, its just a matter of time!'
Go on, flip em over, ya, that's what you've done!
The Council Talks
Hi folks!
The academic year 2007-2008 began with the new students cell taking an initiative in ensuring the overall
personality build up of the MET family.
The MET family exemplifies the word 'differences' with its cosmopolitan crowd, difference of opinions and
different outlook towards life. But all the time, it holds high the sagacious saying “Strength lies in differences
and not in similarities.”
Team is the fuel that has allowed us 'common people', to attain uncommon results. It has enhanced our ability
to work together towards a common vision. It facilitated us to direct individual accomplishments towards our
organizational objectives. Team work is the key that opens any lock.
We are still masters of our fate.
We are still masters of our soul!
Thank You.
- The Editorial Committee
Shrenik Mehta (T.Y.B.Pharm.)
Shruti Kamath (T.Y.B.Pharm.)
Shweta Krishnamoorthy (S.Y.B.Pharm.)
Nidhi Shah (S.Y.D.Pharm.)
8

9
The Students’ Council
Degree
General Secretaries:
Vaibhav Shah (T.Y.B.Pharm.)
Priyam Jhaveri (T.Y.B.Pharm.)
Cultural Secretaries:
Neel Fofaria (S.Y.B.Pharm.)
Manasi Shende (S.Y.B.Pharm.)
Sports Secretaries:
Munib Rais (T.Y.B.Pharm.)
Aashay Shah (S.Y.B.Pharm.)
Treasurers:
Ekta Mehta (T.Y.B.Pharm.)
Smruti Mulgaonkar (S.Y.B.Pharm.)
Editors:
Shrenik Mehta (T.Y.B.Pharm.)
Shruti Kamath (T.Y.B.Pharm.)
Shweta Krishnamoorthy (S.Y.B.Pharm.)
Class Representatives:
Vishal Agarwal (Final Y.B.Pharm.)
Manasi Datar (Final Y.B.Pharm.)
Mihir Shah (T.Y.B.Pharm.)
Deepika Thapar (T.Y.B.Pharm.)
Priyam Gandhi (S.Y.B.Pharm.)
Ankita Goel (S.Y.B.Pharm.)
Amey Kanitkar (F.Y.B.Pharm.)
Tanvi Deshpande (F.Y.B.Pharm)
Diploma
General Secretaries:
Bhavesh Nariyapara (S.Y.D.Pharm.)
Rakshanda Farooqui (S.Y.D.Pharm.)
Cultural Secretaries:
Rubina Shaikh (F.Y.D.Pharm.)
Jeemit Chauhan (F.Y.D.Pharm.)
Asim Jamenis (S.Y.D.Pharm.)
Kajal Kothari (S.Y.D.Pharm.)
Sports Secretaries:
Shoaib Shaikh (S.Y.D.Pharm.)
Tara Choudhary (S.Y.D.Pharm.)
Ameer Shaikh (F.Y.D.Pharm.)
Payal Khawadkar (F.Y.D.Pharm.)
Treasurers:
Vishal Kamerkar (S.Y.D.Pharm.)
Pooja Shah (S.Y.D.Pharm.)
Himanshu Agarwal (F.Y.D.Pharm.)
Editors:
Hitesh Jain (S.Y.D.Pharm.)
Nidhi Choudhary (S.Y.D.Pharm.)
Rohit Lawand (F.Y.D.Pharm.)
Class Representatives:
Bhavesh Nariyapara (S.Y.D.Pharm.)
Rakshanda Farooqui (S.Y.D.Pharm.)
Sagar Labde (F.Y.D.Pharm.)
Shama Shaikh (F.Y.D.Pharm.)

The Students’ Council
Degree
Diploma
10

11
Campus News
MET Utsav
'MET Utsav' as the name suggests the festival of MET was celebrated on the eve of dusshera. Both the staff and
students indulged in this display of 'extravagance'.
The event was held over a period of three days. The first day being the sports day, followed by the second day
consisting of various workshops and events such as tarot, salsa workshop etc. Finally the grand finale was the
last night, 'the cultural night'. The students displayed their talents in the form of dances, songs and the much
awaited fashion show.
The evening was graced by the presence of our respected chief guest Mr. Chagan Bhujbal, Mr. Boman Irani
and Miss Yukta Mookhey. The evening ended with a sumptuous feast. All in all, it was a great and successful
event.
Independence Day
Independence day was celebrated with great gusto by MET especially METIOP.The students of Pharmacy
made Indian subcontinent near the flag to be hoisted with different flowers such a marigolds, and decorated
the ground. Our trustees,along with the chief guest for the day, a grandmother of a student at rishikul
vidyalaya, hoisted the flag, which was followed by the national anthem sung by one and all, with great
passion, patriotism and emotion. Memories of the struggle for independence were relived by our chief guest
who shared it with us all.
The students of rishikul then put up a variety of performances, which included dances, songs and a few
students rendered the national anthem, “saare jahan se accha” on the flute and the piano.
The trustees then gave everyone present speeches telling us the importance of this fateful day. The function
was then followed by tea and snacks for all those present.
Ashadi Ekadashi
th
MET celebrated the auspicious occasion of Ashadi Ekadashi on the 26 of July 2007. The students, teaching
staff and also the non-teaching staff attended the procession organized by Dr. U.B. Hadkar. The procession
was from Father Agnel's college at Bandstand to our very own college. The procession was led by a student or
teacher holding a tulsi plant, as per tradition, followed by students playing the 'zanj' and 'lejhim' accompanied
by students holding orange flags. The non-teaching staff and students sang bhajans all throughout the
procession. On reaching the college a small pooja to appease our lord Vithal, his wife Rakhumai and his
followers Sant Tukaram and Sant Dyaneshwar was conducted. Distribution of Prasad and a short speech on
the importance of Pandharpur-wari by Mr. Page finally ended the event.
Freshers Party
IOP - the inside story
A yearly affair at the MET Institute of Pharmacy, Bandra, the year 2007-2008 fresher's bash more than kept
up with MET's motto of fun and frolic along with a dash of academic achievements and mentor introductions.
The encouraging and warm speeches from the teachers made the newbies comfortable. Finally all inhibitions
were shed when the DJ started spinning his stuff. The new comers at MET started their year on a high note.

Campus News
Industrial Visit to GOA
The T.Y.B.Pharm. and Final Y.B.Pharm. students had their first ever industrial visit to Goa which was organized
th th
by the college, from the 9 to the 13 of January 2008.Though a trip to Goa doesn't sound like an
educational trip, it was a good balance between fun and learning like an educational picnic. Not only did we
learn and gain knowledge out of the experience but we also got to let down our hair and enjoy.
Unichem and Microlabs, the two industries we visited, were kind enough to allow the students to visit their
manufacturing facilities and experience the production of pills and tablets firsthand. Machines and
production procedures which were only read about in text books were seen live by all the students.
US FDA approved industries and sun soaked beaches, this is what we get at MET-an experience to
remember!!
We are extremely grateful to Mr. Narvekar and Mr. Nachnolkar from Unichem India and Mr. Dilip Surana
from Microlabs for allowing us to visit and view their facilities. We also thank Mr. L.Ramaswamy for making
this trip possible.
CRICKET
Munib Rais Abhijeet Lad Mohit Patwardhan
Anand Parikh Shardul Sohani Chandan Gaitonde
Vishal Agarwal Paras Shah Suraj Pawar
Suhas Nandagiria Neel Fofaria
(Held at Azad Maidan.)
FOOTBALL
Munib Rais Abhijeet Lad Rio Boothello
Shardul Sohani Chandan Gaitonde Siddharth Wagal
Siddhesh Mangavkar Tanay Surkund Neel Fofaria
Mohammed
Paras Shah
Aniket Sabnis Rushil Bhatt
st
(1 place. Finals against Oriental College of pharmacy (OCP))
BOX CRICKET (GIRLS)
Diti Dadbhawala Soumya Remesh Manasi Datar
Divija Phatak Forum Sanghvi Dipti Vartak
Saloni Munshi Shraddha Lyma Faroz
st
(1 place. Held at MET. Box cricket finals against OCP)
THROW BALL (GIRLS)
Diti Dadbhawala Soumya Remesh Manasi Datar
Sweta Shah Shruti Parab Aneri Joshi
Divija Phatak Forum Shanghvi Manasi Shende
Shraddha Shinde Shweta K.
st
(1 place. Finals held in Bombay College of Pharmacy(BCP) ground. Finals against Bhanuben Nanavati
College of pharmacy (BNCP))
12

13
Campus News
VOLLEYBALL
Shardul Sohani Vishal Agarwal Sushant Sadamate
Anand Parikh Varun Doshi Arun Maheshwari
Gaurav Mehta Paras Shah
(Held at MET.)
TABLE TENNIS
Boys Team Event:
Anuj Bhargav Munib Rais Varun Doshi
st
(1 Place. Final against K.M. Kundnani College of pharmacy (KMK))
Girls Team Event:
Divija Phatak Manasi Datar Shikha Sakaria
Boys Singles:
Munib Rais
Girls Singles: nd
Divija Phatak (2 Runner up)
(Held at MET)
CHESS
Girls Team Event:
Soundarya V.
Boys Team Event:
Tasneem Arsiwala Priyanka Agarwal
st
(1 Runner Up)
Vivek Jaria
(Held at MET.)
Mohit Patwardhan Ruchin Patel
CARROM
Boys Team Event:
Ganeysh Saive Prasad Warekar Shardul Sohani
Girls Team Event:
Gauri Rane Smruti Mulgaonkar Sofina Jain
Girls Singles: st
Gauri Rane (1 Runner Up)
BADMINTON
Boys Team Event:
Amod Athavale Vaibhav Shah
Shardul Sohane Paras Shah
Girls Team Event:
Tanvi Joshi Diti Dadbhawala
Soumya Remesh Shraddha Shinde

Campus News
RELAY
Boys Team Event:
Shardul Sohani Sanket Mhatre
Abhin Desai Anand Parikh
Girls Team Event:
Mansi Shende Shruti Bhise Gauri Bhise
Boys Singles:
Sanket Mhatre
Girls Singles:
Shruti Bhise
MET IOP slaughtered its opposition in the Sports Competition of the inter – college festival 'Rx' organized by
the Indian Pharmaceutical Association (IPA). The events were held over a week at various locations from Azad
Maidan to our very own MET ground. It was almost a clean sweep with the boys in red winning crucial events
like football, table tennis, box cricket etc. and leaving the opposition behind. MET managed to accumulate
275 points which was the highest amongst the sixteen colleges which participated from all over Mumbai.
At the final tally MET was leading by 65 points and thus clinched the Sports Trophy for the first time ever.
Our Achievements at Rx:
Best College Trophy
Best Dance Trophy
Sports Trophy
Runners-up Cultural Trophy
Runners-up Technical Exhibition
Rx Winners:
Winner of Face Painting:
Pooja Upadhyay (T.Y.B.Pharm.)
Mandar Banbakode (T.Y.B.Pharm.)
Winner of Duet Singing:
Varun Doshi (T.Y.B.Pharm.)
Tanay Telang (T.Y.B.Pharm.)
Winner of Impression Art:
Gauri Rane (T.Y.B.Pharm.)
Pooja Upadhyay (T.Y.B.Pharm.)
Winner of Singing (Western Solo):
Jaidev Singh (F.Y.B.Pharm.)
Winner of Solo Dance:
Prerana Malwadkar (S.Y.B.Pharm.)
Winner of Group Dance:
Siddharth Wagal (Final Y.B.Pharm.)
Siddhesh Mangavkar (Final Y.B.Pharm.)
Gaurav Mehta (Final Y.B.Pharm.)
Mihir Shah (Final Y.B.Pharm.)
Manasi Datar (Final Y.B.Pharm.)
Vaibhav Shah (T.Y.B.Pharm.)
Priyam Jhaveri (T.Y.B.Pharm.)
Tanay Telang (T.Y.B.Pharm.)
Neel Fofaria (S.Y.B.Pharm.)
Kajal Gujjar (S.Y.B.Pharm.)
Ankita Goyal (S.Y.B.Pharm.)
Shraddha Shinde (S.Y.B.Pharm.)
Tanvi Joshi (F.Y.B.Pharm.)
Neha Kashikar (F.Y.B.Pharm.)
Aneri Joshi (F.Y.B.Pharm.)
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15
Campus News
Rx Runners up:
Runners-up of Nail Art:
Pooja Nagori (Final Y.B.Pharm.)
Priyanka Agarwal (Final Y.B.Pharm.)
Runners-up of Cartoon Sketch:
Priyanka Agarwal (Final Y.B.Pharm.)
Priyanka Dhotre (T.Y.B.Pharm.)
Runners-up of Gift Wrapping:
Priyanka Agarwal (Final Y.B.Pharm.)
Pooja Nagori (Final Y.B.Pharm.)
Runners-up of Tattoo Making:
Priyanka Agarwal (Final Y.B.Pharm.)
Vishal Agarwal (Final Y.B.Pharm.)
Runners-up of T-Shirt Painting:
Gaurav Mehta (Final Y.B.Pharm.)
Arun Maheshwari (T.Y.B.Pharm.)
MET does it again! The students of MET rocked their competition at the annual inter-college festival 'RX'. We
bagged the 'Best College Trophy', the 'Best Dance Trophy', the 'Sports Trophy' and the 'Cultural Runners Up'
award. Almost a clean sweep, we lived up to our reputation of blowing our competition away. Besides these,
the students also made us proud bagging many awards in various small events. This is the first time in the
history of MET that we have won the Sports Trophy and the third time in a row that we have won the dance
trophy.
Note: If we have missed out on certain achievements, please accept our apology.
Runners-up of Couple Dance:
Vaibhav Shah (T.Y.B.Pharm.)
Neha Kashikar (F.Y.B.Pharm.)
Runners-up of Singing Male (solo):
Varun Doshi (T.Y.B.Pharm.)
Runners-up of Singing Female (solo):
Prerna Malwadkar (S.Y.B.Pharm.)
Runners-up of Ad-Mad:
Anuj Bhargav (Final Y.B.Pharm.)
Gaurav Mehta (Final Y.B.Pharm.)
Chandan Gaitonde (Final Y.B.Pharm.)
Siddhesh Mangavkar (Final Y.B.Pharm.)
Sushant Sadamate (Final Y.B.Pharm.)
Chaitanya Chandrate (Final Y.B.Pharm.)
Darshana Parmar (Final Y.B.Pharm.)
Shweta Shenoy (Final Y.B.Pharm.)
Paras Shah (F.Y.B.Pharm.)
Pallavi Kolte (F.Y.B.Pharm.)

Campus News
EMERGING TRENDS IN PHARMACY
Our college organized seminars on various topics given by many prominent and eminent people in the
Pharmaceutical world. A program was scheduled wherein 6 seminars were delivered by six extremely learned
and experienced professionals i.e. Dr. Deshpande, Dr. Pandey, Dr. Coutinho, Dr. Krishna Iyer, Dr. Alka Mehta,
Mr. Binoj Kutty.
The program was started off with all the dignitaries lighting the lamp of knowledge after which the Saraswati
Vandana was rendered as a tribute to the Goddess of Knowledge, Saraswati. Dr. Hadkar, our director,
delivered the speech to welcome our speakers.
Our first speaker was Dr. Deshpande, the ex-principal of C.U.Shah College of Pharmacy and the Former
Chairman of the All India Board of Pharmacy Education. He is currently an Advisor to the DTE, Maharashtra
on Pharmacy Education. He has many National and International papers to his credit and has presented
papers at various seminars, conferences and workshops. He is a man of immense experience who has been a
guide and mentor to many of our teachers and pharmacists.
He shared with us, his knowledge on a Unique Approach to Colon Drug Delivery System and how drugs
could be targeted specifically to the colon, bypassing the stomach and the small intestine where absorption
occurs. It shows good patient compliance through oral route of administration. The advantages and factors
affecting colonic absorption, the approach to colonic Drug Delivery and its evaluation-invitro and invivo
were thoroughly discussed.
Colon Drug Delivery System is useful for diseases like Inflammatory Bowel Disease, Crohn's Disease,
Amoebic Dysentry, Colonic Cancer & Irritable Bowel Syndrome. It can be a promising Drug Delivery System
for the delivery of peptides and proteins because of which an Insulin Pill may be developed in the near future.
Dr. Pandey, New Excitements and Challenges in Radiation Biology for Improvement of Cancer Radiotherapy.
He has done his B.Sc. and M.Sc. from the University of Gorakhpur and has done his Ph.D from the University
of Mumbai. He is currently working at the BARC Mumbai. He has won many awards, one of which is the
M.R.Raju Award in 2006, and has many papers published in various journals and has contributed many
chapters to various books. He has taught various courses at the BARC and has presented many seminars.
Cancer is one of the most devastating diseases that kills about 15% of the population and this figure is
expected to rise to 58%.One of the treatments of cancer is through radiotherapy.
Since radiation kills tumor and normal cells, various techniques were presented to counter this problem. Also,
methods to protect normal cells from damage were discussed.
Thus, radiation biology proves to be a useful tool in cancer therapy.
Our third speaker, Dr. Evans Coutinho, presented his seminar on Structure based Drug Design which
included de novo approaches and docking. Dr. Coutinho has done his Graduation and Post Graduation
from UICT. He is currently a Professor at Bombay College of Pharmacy of Medicinal and Pharmaceutical
Chemistry. He has been and is a mentor and a guide to various pharmacists and budding pharmacists. One
of the approaches in rational drug design involves elucidation of structure of the biological target and then
the design of a drug which binds with high affinity to the same. Combining these programs with a program
that can predict the ADME and also suggest various synthetic pathways that can lead to the fruitful discovery
of new drug molecules.
...contd.
16

17
Campus News
After lunch, Dr. Krishna Iyer spoke about the Role of Drug Metabolism in Drug Design. Dr. Iyer has done his
Ph.D from the United States of America and is currently a Professor at the Bombay College of Pharmacy of
Medicinal and Pharmaceutical Chemistry. He has several papers published in National and International
journals and has many seminars to his credit.
Metabolism plays a crucial role in drug design, since it affects the clearance of the drug and the overall
bioavailability. The major site of metabolism is the liver. Metabolism transforms any functional group of a
drug, to give a metabolite which is active, inactive or toxic. It can also convert inactive prodrugs to active
drugs. Genetic polymorphism of certain enzymes within a population can also affect the rate and extent of
metabolism.
Metabolism is the most difficult to predict as animals studies rarely correlate to human metabolism.
Dr. Alka Mehta gave us an introduction to Patents and Patent Application Procedures.
Dr. Mehta has done her M.Pharm. and Ph.D from SNDT. She has done a Post Graduate diploma in Patent
Law and Practice. She has worked at Novartis, Cipla, Wockhardt over a span of 10 years and is now the
Head of Patent Cell of Cipla Ltd.
A patent is a law that protects the right of the inventor and protects ones own product from being copied and
sold. She also emphasized on what could and what could not be patented, the components of a patent, and
its types.
Lastly, Mr. Binoj Kutty introduced us to Cancer Chemotherapeutics using Yeast as a model system.
Mr. Kutty has done his graduation and post graduation in Microbiology. He is currently a Senior Research
Fellow at Radiation Biology and Health Sciences Division at BARC. He has a paper to his credit in FEMS
Microbiology Letter and has also presented posters in several international conferences.
Mr. Kutty explained the use and simplicity of using yeast as a model for anticancer screening and gene
deletion profiling instead of human cells which are complex in nature, and have ethical issues surrounding
their use in experiments. Yeast based bioassays will be technically easier, faster and cheaper than human cell
based bioassays.

Chutkule’
Aisa Bhi Hota Hai !!!!
Two men, one American & an Indian were sitting in a bar drinking shot after shot.
The Indian said to American, "You know my parents are forcing me to get married to this so called homely girl
from a village whom I haven't even met once. We call this arranged marriage. I don't want to marry a woman
whom I don't love.I told them that openly & now have a hell lot of family problems.
The American said, "Talking about love marriages, I'll tell you my story. I married a widow whom I deeply loved
& dated for 3 years. After a couple of years, my father fell in love with my stepdaughter & so my father became
my son-in-law & I became my father's father-in-law. My daughter is my mother & my wife is my grandmother.
More problems occurred when I had a son. My son is my father's brother & so he's my uncle. Situation turned
worse when my father had a son. Now my father's son, i.e. my brother is my grandson. Ultimately, I have
become my own grandfather & I am my own grandson!!!
And you say you have family problems...Give me a break!!
The Ad-Mad Letter
My dear Fair & Lovely (ek chand ka tukda),
You are my TVS Scooty (first love) & my Aiwa (pure passion).
I always BPL (believe in the best) & you are Sansui (better than the best).
You are Domino's pizza (delivering million of smiles) for me.
I have a Colgate energy gel (seriously fresh) feeling for you.
I want you to be my life partner.
We don't need to worry about U'r father who is Ceat (born tough).
I am also Ford Ikon (the josh machine) &
the rest of my family members are pretty Kelvinators (the coolest ones).
If we run away & marry, they will feel like Mirinda (zorka jhatka dhire se lage).
I trust in god who is always Nokia (connecting people).
Soon, we'll known that love is Diary milk (the real test of life).
While saying bye, I must say Pepsi (yeh dil mange more).
Haste - Khelte
- Saloni Munshi
(T.Y.B.Pharm.)
L.G.(Digitally yours)
- Deepak Singh
(F.Y.D.Pharm.)
18

19
Chutkule’
• While making lunch one day for four year old Bruce,
I was stressing the importance of eating his sandwich before a cookie.
”You mean, I have to eat a healthy snack before a good snack?”
• A man was rushing through town, late for an appointment. He was stopped by a very tall man who wanted
him to sign a petition calling for greater recognition of people of height in the making of cars, beds, seats on
the aeroplanes and the like. The man, irritated by the unwanted attention, hurried on, but not before
shouting” Grow up!” over his shoulder.
• Luke's wife bought a new line of expensive cosmetics guaranteed to make her look years younger. After
a lengthy sitting before the mirror applying the "miracle" products she asked,
“Darling, honestly what age would you say I am?"
Looking over her carefully, Luke replied,
“Judging from your skin, twenty; your hair, eighteen; and your figure, twenty-five."
"Oh, you flatterer!" she gushed.
"Hey, wait a minute!" Luke interrupted. "I haven't added them up yet.”
• A young woman was having a physical examination and was embarrassed because of a weight problem.
As she removed her last bit of clothing, she blushed. "I'm so ashamed, Doctor," she said, "I guess I let myself go."
The physician was checking hers eyes and ears. "Don't feel ashamed, Miss. You don't look that bad."
“Do you really think so, Doctor?" she asked. The doctor held a tongue depressor in front of her face and said,
"Of course. Now just open your mouth and say moo.”
• An elderly couple were driving across the country.
The woman was driving when she got pulled over by the Garda.
The Garda said, "Ma'am did you know you were speeding?"
The woman turns to her husband and asked, "What did he say?"
The old man yelled, "He says you were speeding!”
The Garda said, "May I see your license?"
The woman turned to her husband and asked, "What did he say?"
The old man yelled, "He wants to see your license!"
The woman gave him her license.
The Garda said, "I see you are from Mayo.
I spent some time there once and had the worst date I have ever had."
The woman turned to her husband and asked, "What did he say?"
The old man yelled, "He thinks he knows you!”
• A young and beautiful woman gets into the elevator, smelling like expensive perfume. She turns to the
old Italian woman on the elevator with her and says arrogantly, "Giorgio - Beverly Hills, $100 an ounce!"
Another young and beautiful woman gets on the elevator and also smells of very expensive perfume. She
arrogantly turns to the old Italian woman and says, "Chanel No. 5, $150 an ounce!"
About three floors later, the old Italian woman has reached her destination and is about to get off the
elevator. Before she leaves she looks both beautiful women in the eyes, turns, bends over, and farts.
“Broccoli - 49 cents a pound.”

Chutkule’
• A middle-aged couple, with two beautiful daughters, decided to try one last time for the son they
always wanted. Soon, the wife became pregnant, and, nine months later, delivered a baby boy. The
joyful father rushed to the nursery to see his new son, but was horrified to find an incredibly-ugly baby.
He went to his wife and said, "I cannot possibly be the father of that hideous child. Look at the two
beautiful daughters I fathered." When his wife blushed, he became suspicious, and demanded,
"Have you been fooling around on me?”
His wife confessed, "Not this time."
• Sam & Becky are celebrating their 50th wedding anniversary and Sam says to Becky
“So, Becky, I was wondering... Have you ever cheated on me?"
Becky replies, "Oh Sam, why would you ask such a question now? You don't want to ask that question..."
"Yes, Becky, I really want to know. Please..."
"Well, all right, 3 times..."
"3, hmmm, well when were they?"
"Well, Sam, remember when you were 35 years old and you really wanted to start the business on your
own and no bank would give you a loan... Remember, then one day the bank president himself came
over the house and signed the loan papers, no questions asked... Well..."
"Oh, Becky, you did that for me! I respect you even more than ever, to do such a thing for me....
So when was number 2?"
"Well, Sam, remember when you had that last heart attack and you were needing that very tricky
operation, and no surgeon wanted to touch you...
Then remember how Dr. De Bakey came all the way up here to do the surgery himself and then you were
in good shape again... Well...."
"Oh my God!! Becky, you should do such a thing for me, to save my life... I couldn't have a more
wonderful wife... To do such a thing, , you must really love me darling... I couldn't be more moved...
So, all right then, when was number 3?”
"Well, Sam, remember a few years ago, when you really wanted to be president of the congregation....
And you were 47 votes short...."
• Katrina's teacher asked 3 year old Katrina, if she had any pets at home.
“No,”Katrina replied.
She thought for a minute and then replied,”But I have a fish in the freezer.”
20

21
Chutkule’
Top 10 Reasons: Why God Created Eve
10. God worried that Adam would frequently become lost in the garden because he would not ask for
directions.
9. God knew that Adam would one day require someone to locate and hand him the TV remote.
8. God knew that Adam would never go out and get himself a new fig leaf when his seat wore out and
would, therefore, need Eve to go get one for him.
7. God knew that Adam would never be able to make a doctor's, dentist, or haircut appointment for
himself.
6. God knew that Adam would never be able to remember which night to put the garbage on the curb.
5. God knew that if the world was to be populated, men would never be able to handle the pain and
discomfort of childbearing.
4. As "Keeper of the Garden," Adam would never remember where he left his tools.
3. Apparently, Adam needed someone to blame his troubles on when God caught him hiding in the
garden.
2. As the Bible says, "It is not good for man to be alone!"
And finally, the number ONE reason that God created Eve...
1. When God finished the creation of Adam, He stepped back, scratched His head, and said,
“Ok, I can do better than THAT!".
RIDDLES
Q: What do you do if a blonde throws a grenade at you?
A: You pick it up pull the pin & throw it back.
Q: What happened to the blonde tap dancer?
A: She slipped off and fell down the drain.
Q: How did the blonde try to kill the fish?
A: She tried to drown it.
Q: What do you call a blonde with half a brain?
A: Gifted!
Q: How many honest, intelligent, caring men in the world does it take to do the dishes?
A: Both of them

Chutkule’
Rules that guys wished girls knew..........
1. If you think you're fat, you probably are. Don't ask us.
2. Learn to work the toilet seat: if it's up put it down.
3. Don't cut your hair. Ever.
4. Birthdays, Valentines, and Anniversaries are not quests to see if he can find the perfect present, again!
5. If you ask a question you don't want an answer to, expect an answer you don't want to hear.
6. Sometimes, he's not thinking about you. Live with it.
7. Don't ask him what he's thinking about unless you are prepared to discuss such topics as navel lint, the
shotgun formation and monster trucks.
8. Get rid of your cat. And no, it's not different, it's just like every other cat.
9. Dogs are better than ANY cats. Period.
10. Sunday = Sports. It's like the full moon or the changing of the tides. Let it be.
11. Shopping is not sport.
12. Anything you wear is fine. Really.
13. You have enough clothes.
14. You have too many shoes.
15. Crying is blackmail. Use it if you must, but don't expect us to like it.
16. Your brother is an idiot, your ex-boyfriend is an idiot and your Dad probably is too.
17. Ask for what you want. Subtle hints don't work.
18. No, he doesn't know what day it is. He never will. Mark anniversaries on a calendar.
19. Yes, pissing standing up is more difficult than peeing from point blank range.
We're bound to miss sometimes.
20. Most guys own two to three pairs of shoes-what makes you think we'd be any good at choosing which
pair, out of thirty, would look good with your dress?
21. Yes and No are perfectly acceptable answers.
22. A headache that lasts for 17 months is a problem. See a doctor.
23. Your Mom doesn't have to be our best friend.
24. Foreign films are best left to foreigners.
25. Check your oil.
26. Don't give us 50 rules when 25 will do.
27. Don't fake it. We'd rather be ineffective than deceived.
...contd.
22

23
Chutkule’
28. It is neither in your best interest nor ours to take the quiz together.
29. Anything we said 6 or 8 months ago is inadmissible in an argument.
All comments become null and void after 7 days.
30. If you don't dress like the Victoria's Secret girls, don't expect us to act like soap opera guys.
31. If something we said can be interpreted two ways, and one of the ways makes you sad and angry,
we meant the other one.
32. Let us ogle. If we don't look at other women, how can we know how pretty you are?
33. Don't rub the lamp if you don't want the genie to come out.
34. You can either ask us to do something OR tell us how you want it done - not both.
35. Whenever possible, please say whatever you have to say during commercials.
36. Christopher Columbus didn't need directions, and neither do we.
37. Consider Golf a mini-vacation from you. We need it, just like you do.
38. The relationship is never going to be like it was the first two months we were going out.
“Spelling Bee Confusing”
If GH can stand for P as in Hiccough
If OUGH stands for O as in Dough
If PHTH stands for T as in Phthisis
If EIGH stands for A as in Neighbor
If TTE stands for T as in gazette
If EAU stands for O as in Plateau
Then…the right way to spell “POTATO” should be: -
“GHOUGHPHTHEIGHTTEEAU”!!!!!
- Saloni Munshi
(T.Y.B.Pharm.)

Chutkule’
K....K....Kahani Student Ki ....
Exams R compulsary in our life, because they are ' Kasauti Zindagi Ki....'
Teacher may appose this ' Kyonki Teacher Bhi Kabhi Student Thi....'.
There is nothing to worry about these exams because they are 'Kahani School School Ki....'.
Even there is a possibility that 'Kahin Kisi Roz...' these exams are to be banned.
Any way all this depends upon our 'Kundali..'.
Yet after all these arguments, question remain in our mind- ' Kyon Hota Hai Exam ?'
Well no one has the answer, but I give one suggestion, try & try until you succeed; after all -' Koshish Ek Asha...'
The positive point of exam is that they R able to determine that
'Kismey Kitna Hai Dum...' & ' Kamzor Kadi Kaun....'.
Every one while sitting in the exam-hall prays that ' Koi Apana Sa....' will come & help.
When we keep others copies,the 'apana sa' person says, 'SSSHHH.....Koi Hai ! '
So we get ' Khauff ' of getting into ' Kashmakash ',after all we should not do such a bad ' Karm '.
These exams really brings ' Bandhan 'on ourminds ,but still ‘Kitne Kool Hai Hum'.
We all have 'Choti Si Asha....' to pass b'cause ' Kehta Hai Dil '.
Dont led down the 'Kalash ' of heritage. After all every 'Hadsa ' gives rise to a 'Kamaal '.
All these thing should be managed by we without seeing any ' Raah' of ' Sonpari ' or 'Shaktiman'.b'cause in
doing so U will be building up 'Ek Mahal Ho Sapano Ka...', but we should never do 'Yaatra' in dreams.
Always beleive in ' Haqeekat'.
So with our ' Umeed ' that U get my view; I would not indulge in further 'Tu-TU....Main-Main....' on this topic.
- Mahesh Kharade
(F.Y.D.Pharm.)
24

25
Model Mentor
Dr. U. B. Hadkar, Director - IOP
Follow the Leaders
A simple lab method for the determination of Interfacial Tension of two liquids has been developed by
Dr. U. B. Hadkar. The important feature of this method is the use of Hadkar's Factor to calculate the interfacial
tension.
The interfacial tension is an important property in the pharmaceutical industry which determines the stability
of emulsions. The method can be used to study the effect of surfactant on the surface tension of the liquid.
This is a very important and ingenious discovery as the regular method to determine Interfacial Tension is very
tedious and time consuming.
Besides his discoveries and inventions in the lab, our beloved director Hadkar Sir has also featured on the
cover of Pharma Bio World magazine this year.
Dr.(Mrs.) Abha Doshi, Principle (Degree) - IOP
Dr.(Mrs.) Abha Doshi presented a research paper on 'Design and Evaluation of oral patches for Apthous
nd th
Ulcer' in PSWC 2007 held in Amsterdam (Neatherland) from 22 April to 25 April 2007. The paper was
co-authored by Mrs. Sheeja Koliyote and Mrs. Bhagyashree Joshi.
The oral patches for aphthous ulcer were prepared using tannic acid with glycerine. Tannic acid has antibacterial
anti-enzymatic and astringent properties. It has constringing action upon mucous tissues such as
tongue and inside of mouth. Tannic acid is used to treat ulcers, toothache and wounds. Glycerine of tannic
acid is effectively used in the treatment of aphthous ulcers, but being viscous liquid, the residence time is less
which is not sufficient for the treatment for the treatment. To increase the residence time, mucoadhesive oral
patches of tannic acid with glycerine were formulated using mucoadhesive polymers like PVA and Sodium
alginate. The patch besides treating the ulcer acts as a physical barrier to irritation. The three layered oral
patches were prepared using mucoadhesive polymer, PVA in which the drug was sandwiched between the
polymer layers. Mono layered Oral patches were also prepared using Sodium alginate. The films were
evaluated for their mechanical strength, folding endurance, drug content uniformity, swelling, in vitro
residence time, in vitro release, in vitro bioadhesion and in vivo mucoadhesion. Transmucosal delivery of
tannic acid improves the residence time of the drug at the site of action i.e. mouth ulcer. The oral patches
were prepared using polymers PVA and sodium alginate both of which are hydrophilic and water soluble.
The residence time of PVA patch is comparatively more as compared to sodium alginate but the
mucoadhesion was better for sodium alginate.
Dr. Abha Doshi, Mrs. Sheeja Koliyote and Mrs. Bhagyashree Joshi also presented a research paper in the
th
5 world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology on 'Design and
evaluation of buccal films of Diclofenac Sodium, which was held in Geneva (Switzerland) in March 2006.

Poesy
Don't want a fairy tale
Don't want riches and gold,
Don't want knights in shining armors, who are bold,
Don't want a prince charming or a handsome male,
I don't want a fairy tale,
All I want is a heart call,
As pure and pristine as a dove in the fall,
Someone who won't let me sip my bitter tears,
Someone who would mend my wounds and remove my cardiac spears,
Someone to light my eyes and to splash me with a kiss,
Someone to watch my joy and shower me with eternal bliss,
Some soul to ease my heart ache,
Some soul to burn me like fire in the midst of a lake,
All in the name of love, Nothing for love,
In the world of reality,
Where you either live a happy life or embrace immortality,
I want, what I know I would get,
No high praises to the Lord, I would lay my hands on this bet,
If there exists God in the celestial skies,
Who makes and breaks all ties,
I wish for one thing,
From the only king,
Don't want anything but this illusion to fail,
I DON'T WANT A FAIRY TALE!
From verse to verse
- Ankita Goyal
(S.Y.B.Pharm.)
26

27
Poesy
I know things are better left unsaid,
Yet have to tell u what has been running through my head,
I don't know if what I'm feeling is wrong or right,
But you say on my mind both day and night.
I am not going to tell you that I am in love wit you,
But for you, I have got feelings that I know are very true.
I love being with you everyday
it makes me want you more in every way,
I could just sit and watch you for days,
You have gotten me wrapped in your mesmerizing ways.
I love seeing your big beautiful smile,
That makes everything in my life worthwhile,
I want to be with you as more than just friends,
But I guess that's where my fantasy ends.
If only, you'd give a chance, you'd see,
How great together we could be,
Until that day comes to par,
I will just keep admiring you from afar.
SMILE
WHEN YOU ARE SAD,
AND FEELING VERY BAD,
SOMEONE GIVES YOU A SMILE.
HOW DO YOU FEEL FOR A SMILE.
HOW DO YOU FEEL FOR A WHILE?
YOU THINK THE WHOLE WORLD IS AGAINST YOU,
BUT THERE IS SOMEONE WHO REALLY CARES FOR YOU.
IF NOT,THERE IS A SWEET LITTLE SMILE,
THAT WILL BE YOUR COMPANION THROUGH YOUR LIFE.
HENCE IT MAY NOT BE WRONG TO SAY THAT
“SMILE COSTS NOTHING,BUT MEANS A LOT”
- Shraddha Shinde
(S.Y.B.Pharm.)
- Mitul Vora
(T.Y.B.Pharm.)

Poesy
The winter blows, the blue lakes and the garden greens,
But without you around, everything is just not seen,
Doubtful if for a single moment I didn't think of you,
You were on my mind the whole night till the skies blue.
Innocently tried to catch your glimpse in the running crowd,
Knowing the fact that you are somewhere around.
I wont ever hurt you,have no fears,
That's a promise of all my tears.
Sharing my feelings to someone else is not my case,
So I try hiding my broken heart beneath a laughing face.
- Shraddha Shinde
(S.Y.B.Pharm.)
28

29
Poesy
Thanks Giving To Nature
I look up the skies,
Warm, bright, cheerful and clear.
Thinking of the ones,
I cherish in my heart and memoirs so dear.
Gentle warm breeze flutters by,
Reminding me of natures beauty.
And the creating of me,
Which seemed his prime duty.
Tenderly I hear birds twitter,
Composed, tranquil and soothing note for you and me.
How serene and beautiful I wonder,
To be born so free?
I hear the music of rippling water,
With the ducks to swine in line
And softly I say, “Thank you savior
For giving me the world so fine,
For being so nice and kind!”
- Megha Unhelkar
(F.Y.B.Pharm.)

Poesy
Dr. Abha Doshi
Principal (Degree)-IOP
30

31
We Mean Business!
ANTIPSYCHOTIC DRUG – THE ANSWER TO OPIOD THERAPY
Something that we are best at
Recent Research concluded that a long-approved oral antipsychotic drug can stop the addictive properties of
opioid painkillers in mice.
The researchers injected a small dose of trifluoperazine (a drug used in the treatment of mental diseases such
as schizophrenia) into laboratory mice hooked on morphine. After a few hours their addiction was observed
to be gone. This was the first time any study has shown the anti-addictive property of trifluoperazine.
Trifluoperazine inhibits calmodulin - a molecule that is required for the activation of an enzyme called
calcium/calmodulin-dependent protein kinase-2. In previous studies, CaMK-2 was observed to play an
important role in the generation and maintenance of opioid tolerance. Tolerance is a hallmark of drug
dependence.
Trifluoperazine targets this pathway, which then stops the addiction. When this occurs, one can still use a
relatively low dose of the painkiller to achieve fairly good pain control and no drug dependence.
Opioids such as morphine are commonly used in pain management, but many patients are wary of taking
them because of concerns over addiction or adverse side effects.
This breakthrough will thus help in pain management without serious repercussions like addiction and
withdrawal symptoms.
GARLIC - A HEART PROTECTIVE
After a heart attack it is important to restore the flow of blood to the heart so that damage to the heart muscle
can be minimised. However, the return of blood flow can paradoxically cause further damage leading to
ischemic-reperfusion injury, due to the release of free radicals. Free radicals cause oxidative stress to the
heart cells, resulting in reduced cardiac function and irreversible tissue injury. This can be potentially fatal to
patients undergoing heart surgery to remove clots or repair heart defects.
Antioxidants, which can “mop up” free radicals before they do any harm, have been shown to reduce the
severity of damage to the heart. However, the therapeutic use of antioxidants is limited by their toxicity. In light
of several recent studies showing that garlic can limit the depletion of natural heart antioxidants, a research
team from India designed a study to investigate whether garlic could protect against oxidative stress in rats.
The team found that regular consumption of raw garlic prevented oxidative stress and the resulting tissue
damage. Rats that were given a consistent diet of garlic were found to have much higher levels of antioxidants
and lower levels of the chemicals that accompany oxidative stress. The damage to their hearts following
ischemic-reperfusion injury was also significantly lower. Further studies in humans are needed, but it was
concluded that garlic has important potential to save the lives of patients undergoing heart surgery.
- Sneha Ramaswamy
Dr. Sonali Naik

We Mean Business!
BIOSENSORS
A biosensor is a device that detects, records, and transmits information regarding a physiological change or
the presence of various chemical or biological materials in the environment. More technically, a biosensor is
a probe that integrates a biological component, such as a whole bacterium or a biological product (e.g., an
enzyme or antibody) with an electronic component to yield a measurable signal. Biosensors, which come in a
large variety of sizes and shapes, are used to monitor changes in environmental conditions. They can detect
and measure concentrations of specific bacteria or hazardous chemicals; they can measure acidity levels
(pH). In short, biosensors can use bacteria and detect them, too.
The first biosensor developed was intended for environmental monitoring. It used an antibody—a protein
substance produced in the blood or tissues in response to a specific antigen, such as a bacterium or toxin
normally foreign to the body. Antibodies destroy invading bacteria and neutralize organic poisons, forming
the basis of immunity. Thus, first biosensor was called an immunosensor
Genetically engineered bacteria have been designed to give off a detectable signal, such as light, in the
presence of a specific pollutant they use as food. They may glow in the presence of toluene, a hazardous
compound found in gasoline and other petroleum products. They can indicate whether an underground fuel
tank is leaking. These informer bacteria are called bioreporters. In 1990, when a bioreporter of naphthalene
was developed and tested at the University of Tennessee at Knoxville (UTK), the ability of these bacteria to
glow was demonstrated for President George Bush during his visit to UTK.
In the mid-1980s, Tuan Vo-Dinh, Guy Griffin, and others were looking for a way to use light to detect cancercausing
agents in groundwater. They attached to the end of an optical fiber an antibody that reacts
specifically with the carcinogen benzo(a)pyrene (BaP). The anti-BaP antibody on the end of the fiber was
immersed in a sample of groundwater. The antibody was allowed to bind the BaP in the groundwater sample.
The antibody-BaP reaction product gives off light if illuminated by light of the right wavelength. So the right
light was aimed through the fiber into the groundwater sample. After 5 to 10 minutes, the reaction product
fluoresced, and the fluorescence was transmitted back up the fiber and measured. These successful results,
reported in 1987 by Vo-Dinh and colleagues.
In another approach to the use of immunosensors, microspheres of different sizes are labeled with antibodies
that bind to different bacteria; thus, microspheres of one size have one particular antibody and microspheres
of another size have a different antibody and the bacteria that become bound are detected by the color of
fluorescent dye with which they are stained. In a 1995 paper, Bill Whitten that up to 100 different types of
bacteria can be identified simultaneously because the stained bacteria all would fluoresce at one wavelength
of light.
A chip on your fingertip may someday measure and transmit data on your body temperature. An array of
chips attached to your body may provide additional information on blood pressure, oxygen level, and pulse
rate. This type of medical telesensor, are being developed.
...contd.
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Tom Ferrell has shown that a 2 × 2-millimeter (mm) silicon chip attached to the skin can measure body
temperature. The chip contains a temperature sensor in an integrated circuit, a lithium thin-film battery that
supplies the very low level of power required by the circuit and signal processing and transmission
electronics, and an antenna that sends the data by radio signals.
Temperature changes of a millionth of a degree can be measured using micro-cantilever. The temperature is
measured by coating the silicon surface with gold or aluminum, which expands at a different rate than silicon.
Because the difference in heat expansion between silicon and gold affects bending of the microcantilever,
Chemical reactions generate heat, so this device can be used as a microcalorimeter to measure the heat of
an enzyme-catalyzed reaction or a chemical reaction in a reaction volume of one microliter (1 µl).
The researchers have made dramatic progress in miniaturization of clinical and chemical
laboratories—another aspect of biosensor.
- Dr. U. B. Hadkar
Director - IOP
TITLE: A SURVEY ON HAZARDS OF FOOD COLOURS
SUMMARY:
Colours are present in most of the food products that we consume, like the Blue colour used in beverages,
candy and baked goods has a tendency to cause cancer. Similarly there is sufficient evidence that the colour
RED 3 used in canned fruits, cocktails etc. causes thyroid tumors however there is a lot of ignorance about
their effects.
The knowledge possessed or the avenues of obtaining it are not enough. All the above mentioned colours are
approved by the FDA and they are simple examples of the level of harm they can cause to us.
To find out the level of this ignorance of the people we have conducted a survey on this topic.
On the basis of the survey conducted of about 100 individuals we could infer that there was not enough
knowledge about the food colours:
• 20% of the population could not decipher the codes representing these colours.
• Since, the level of awareness was not up to the mark, they refused to compromise on the use of prepackaged
food irrespective of the health hazards.
• 8% individuals were unaware that 'golas', 'pav bhaji' contain unregulated food colours.
• 2% individuals were aware of certified colours, however even they did not bother to check the products
they consume for the food colour information.
• 80% individuals were unaware that asthma can be aggravated by use harmful food colours.
• 98% individuals feel that even natural food colours should be strictly regulated. They were unhappy with
the efforts of regulatory authorities to create awareness.
• According to the common people awareness amongst the population should be created via
pamphlets, newspapers, television ads etc.
- Priyam Jhaveri
Shrenik Mehta
Vaibhav Shah
Kalyani Asgaonkar
Dr. Sonali Naik

We Mean Business!
NANODRUG DELIVERY
Nanotechnology offers an unprecedented opportunity in the rational delivery of drugs and vaccines.
Examples of nanotechnology applied in pharmaceutical product development include organic nanoplatforms
such as polymeric, lipid (e.g., liposomes, nanoemulsions, and solid–lipid nanoparticles), selfassembling
structures, and dendrimers as well as certain inorganic nano-platforms including metal (e.g.,
gold and silver), and silica-based nanostructures. Nano-sized delivery systems offer numerous advantages:
small particle size, narrow size distribution, protective insulation of drug molecules to enhance stability,
surface features for target-specific localization, specific types of materials that respond to an applied
stimulus, the ability to deliver multiple therapeutic payloads in a single formulation, and temporal control
over their release, combination of drugs with electromagnetic energy delivery for synergistic therapeutic
effects, & the opportunity to combine imaging modality and drugs to monitor the therapeutic effects in real time.
Despite these seemingly clear advantages, the number of currently approved nanotechnology-based
products for routine clinical use is fairly limited. Select examples include doxorubicin in long-circulating
liposomes and paclitaxel in albumin nanoparticles for systemic administration, rapamycin in a nanocrystal
formulation for oral administration, and estradiol in oil-in-water nanoemulsion for topical application. The
major barriers to clinical translation of nanotechnology-based products are mainly focused on scale-up and
manufacturing issues, as well as safety concerns. Due to the inherent complexity of some of the nanosystems,
large-scale manufacturing under current good manufacturing practices guidelines and appropriate quality
control can become a major stumbling block. Certain nanomaterials, such as fullerenes, carbon nanotubes,
and quantum dots have excellent properties, but their systemic distribution and clearance profiles, tissue and
cellular interactions, and associated toxicity, especially upon chronic in vivo administration, have not been
clearly addressed. The biodistribution of a nano-encapsulated drug will be quite different from that of the free
drug. Therefore regulatory agencies will require comprehensive preclinical dose-escalating toxicity studies in
multiple animal species before they can approve the final product. The associated complexities and higher
cost of these studies profoundly affects clinical development. These concerns become even more magnified
with complex nanosystems having multiple therapeutic payloads and additional targeting and imaging
functionalities.
Based on the advantages and certain challenges for nanotechnology-based delivery system, judicious
selection of materials and products for initial preclinical and clinical evaluation will be essential. Several
products based on liposomes, nanoemulsions, polymeric nanoparticles, and gold nanoparticles are
currently in advanced preclinical and clinical stages. Success of these trailblazer nano-products will provide
the essential impetus for further development of more sophisticated technologies with significant benefits to
patients.
- Sneha Ramaswamy
(T.Y.B.Pharm.)
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RADIOACTIVE SCORPION VENOM FOR FIGHTING BRAIN TUMOR
'Human Brain' is the most important asset that 'Man' has been bestowed with and it is this Human Brain which
gives man the power of imagination, creativity and his ceaseless efforts for the betterment of mankind.
It is this very Brain, when got crippled with a deadly disease such as Brain Tumor, Man has fought against it
with newer ideas day-in and day-out.
As the saying goes, “When the going gets tough,
The tough gets going”…
This topic deals with such an idea.
The first thing that comes to our mind when we think of Scorpions is 'its deadly sting ' or 'the zodiac sign'.
But in recent times there is much more to the use of 'Scorpion Venom.'
A Glioma is a primary Central Nervous System tumor that arises out of glial cells.
The most common site of involvement is Brain, but it also affects the Spinal cord, optic nerves and other parts
of CNS.
Out of these, 'Malignant Brain Glioma' is the worst of all.
The effects and consequences of malignant glioma are being studied worldwide and these are some of the
startling statistics:
rd th
• It is the 3 & 4 leading cause of cancer-related deaths among men & women.
• The most alarming one is that only less than 20% of the patients live after 1 year of diagnosis!
This indicates how lethal these gliomas are.
Since Cancer itself is so deadly, to counter it we need an 'equally aggressive approach'. Hence studies are
under way for “ Venom Therapy ”.
When Brain Tumor treatment was being focused, the researchers zeroed down to the use of 'Scorpion Venom'
because of the ability of the Venom protein to act as a 'carrier' for Targeted Radiotherapy. This therapy is a
Revolution in the field of Radiotherapy as here there is 'internal' administration of radiation.
Scientists at Trans Molecular Corp. in Cambridge, Massachusetts created the radioactive version of Scorpion
venom & named it TM-601.
There were 2 reasons why scientists thought of this approach:
1. Venom protein, TM-601 has its receptors on the brain tumor cells. Because of this ability, Scientists linked
it to a radioactive agent known as Samporin, which is I-131*. Hence, it was ensured that the drug would
'selectively' go & bind only to the tumor cells & now-where else.
2. Upon reaching, this radioactive I-131* releases radiation at the target & destroys the leftover tumor cells,
without affecting the normal tissues.
Experimental Research:
• Place: Cedars-Sinai Medical Center in California.
• Volunteers: 18 patients
st
• Concerns: Safety- as these were the 1 Human trials using this technique.
Dose- as any excess was feared to lead to radiation toxicity.
...contd.

We Mean Business!
The study, which compiled these results, involved 18 patients who first had surgical removal of malignant
gliomas – the deadliest form of brain tumor. However, certain gliomas are always left behind after a tumor in
the brain is surgically removed and they are known to resist treatment.
Researchers then inserted the radioactive scorpion venom protein i.e.
TM-601 + I-131* and found that it could deliver radioactive iodine through the blood barrier to gliomas. In
order to maintain safety, researchers used low doses of TM-601 and the radiation levels were also kept below
therapeutic standards.
Results showed that the patients reached total radiological responses and MRI scans showed that no tumors
existed.
Although average survival for the patients was 27 weeks, these patients were alive even three years after the
treatment.
Another positive finding was the whatever the level of dosage, no side effects were noticed. Also, the effects of
radioactivity seemed to recede after 24 hours.
Dr. Adam Mamelak led the study. He said “It isn't a miracle but a breakthrough and provides hope for
illnesses which earlier had no cure”. He further added that after more research is carried out, this technique
might also be used in combination with other treatments like chemotherapy.
Phase II Trial is currently under investigation in US on 54 patients. No toxicity has been reported even with a
dose of 40 miC/week.
Radioactive Scorpion Venom Technique has attained success at an initial stage of research & this is just a
beginning, maybe it sounds like Science fiction now, but in near future it truly will be a 'sure shot' therapy for
fighting cancer.
SYNTHETIC BIOLOGY
– ENGINEERING BIOLOGICAL SYSTEMS FOR MIRACULOUS ADVANTAGES
- Saloni Munshi
(T.Y.B.Pharm.)
The discovery of mathematical logic in gene regulation in the 1960s (e.g. the lac operon) and early
achievements in genetic engineering in the 1970s, such as recombinant DNA technology, paved the way for
today's Synthetic Biology which by defination is 'the design and construction of new biological parts, devices,
and systems and the re-design of existing, natural biological systems for useful purposes'. This approach
combines the knowledge from various disciplines including molecular biology, engineering, mathematics
and physics to design and build novel proteins, genetic circuits and metabolic networks. It is an intrinsically
interdisciplinary activity that thrives at the interface of biologists and engineers, where biologists contribute
their deep insight into the molecular mechanisms of biological processes and cellular design principles,
while the engineers can contribute their perspective and tools for systems behavior and design procedures.
Synthetic biology aims to create novel behaviors through the engineering of genetic elements to allow the
construction of novel genomes from standard parts or from scratch, as one might construct an electronic
...contd.
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circuit from electrical components and the integration of basic elements into circuits that implement more
complex functions.
Potential applications range from Medicine to Energy generation including the development of sophisticated
non-native behaviors such as biostability, oscillations, proteins customized for biosensing, optimized drug
synthesis, programmed spatial pattern formation and bioengineering of synthetic minimal cells. Over the
next 10 years synthetic biology may provide radical advances in areas like biomedicine, synthesis of
biopharmaceuticals, sustainable chemical industry, environment and energy, production of smart
materials/biomaterials and security.
Objectives
SYNTHETIC BIOLOGY: a new conceptual frame that:
[i] Addresses biological systems with the tools and the descriptive language of Engineering.
[ii] Tackles old questions and challenges with fresh approaches inspired in electric circuitry and
mechanical manufacturing and
[iii] Pursues the creation of new materials with á la carte properties based on the rational combination of
standardized biological parts decoupled from their natural context.
Biomedicine
Complex molecular devices for tissue repair/regeneration-Development of small macromolecular
assemblies composed of a sensor and a group of enzymes, which could be used to sense damage in for
example blood vessels and proceed to repair them by dissolving plaques and stimulating endothelial
regeneration.
Smart drugs- A smart drug includes a diagnostic module that is programmed with medical knowledge; it is
capable of directly sensing of molecular disease indicators and making a diagnostic decision. This decision is
then translated into drug activation.
Biological delivery systems- design of organism-friendly devices that will sense (for example) changes in
particular hormones and will proceed to secrete a chemical or biological compound in response.
Vectors for therapy- The design and modification of viruses to deliver healthy genes to the target tissue in an
efficient way, promoting specific recombination and integration of synthetic genes with the existing genome.
Personalized medicine- Biopharmaceutical drugs will be adapted in their mode of action, formulation,
dosage, and release kinetics to the specific requirements of the patient.
Cells with new properties that improve human health
In vivo synthesis of small-molecule pharmaceuticals:
Complex natural products - Engineering biological pathways, for example into bacteria will provide access to
naturally active classes of compounds that have previously been too complex to synthesize A sustainable
chemical industry - Environmentally friendly production of chemicals by Engineered Microorganisms to
produce in bulk Raw materials required by the industry.
...contd.

We Mean Business!
Environment and energy Bioremediation - The rational modification of bacteria and other microorganisms
such as fungi to eliminate toxic waste from soil has been a Holy Grail in remediation technologies for many
years. Improved abilities to design complex behavior and degradation capabilities as well as adaptation
strategies within ecosystems might bring this dream into reach.
Production of energy- The challenge is to design a set of converging chemical pathways that allow an
essentially quantitative conversion of readily available solar energy and natural or waste materials to i.e.
biofuels.
Experimental Work Done
Utilizing a synthetic biology approach, the construction of a modular platform for the highly efficient synthesis
of complex saccharide structures for which no economic synthesis scheme exists to date has to be done.
A forward engineering approach is used in order to
[i] modularize Escherichia coli's cell metabolism into an energy module and a synthetic module for
saccharide production and
[ii] to adapt the modules' productivity and sensitivity by reengineering its key enzymes
Together, these activities will lead to the implementation of “biochem-bricks”, chemical synthesis modules
that can be freely combined with other such modules without the interference on dynamic
level that is typical for cellular regulation.
Extraction of artemisinin from the wormwood plant is labor intensive and, in some developing countries, it is
produced by a diesel fuel purification process that may retain toxic impurities in the final drug product. To
produce the artemisinin, genetically modified microbes have been produced. This approach also produces a
reliably pure compound. While synthetic biology can be used to create any number of useful chemicals
called isoprenoids that form the basis for products such as perfumes and flavorings, focus is more on the
creation of much-needed pharmaceuticals, such as artemisinin, for the developing world.
Conclusions drawn and achievements
Synthetic biology will help develop the foundational understanding and technologies to build biological
components and assemble them into integrated systems to accomplish particular tasks. Synthetic biology will
improve researchers' understanding of the natural world and holds great promise in producing socially
valuable advances in information processing, energy production and environmental applications, chemical
and materials manufacture, and human health.
Synthetic biology currently offers the ability to study cellular regulation and behavior using de novo networks,
while future applications of synthetic systems will also extend to the fields of medicine and biotechnology.
Engineered E. coli populations have been programmed to form spatial patterns with various shapes. Such
patterning systems will serve as templates for building user defined physical structures, with implications for
programmed tissue regeneration and the formation of complex biomaterials. Bacteria, like those that
degrade parathion, will be engineered to treat biological wastes or to aid in the clean up of toxic spills. In the
future, engineered protein biosensors will enable the creation of organisms with exquisite detection capabilities
...contd.
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that can identify internal and external hazards such as pathogens or explosives. As exemplified by the
development of artemisinin-producing E. coli, synthetic networks will also be utilized to supplement and
potentially supplant current methods for the production of medicines and simple polymers. Although the
ability to program cell behaviors is still in its infancy, it is clear that the power to freely manipulate the set
of instructions governing the behavior of organisms will have a tremendous impact on our quality of life
and our ability to interact with and control the physical world surrounding us.
Future action plans
For future biotechnology applications, the synthetic regulatory modules described must be interfaced with
sensory inputs and biological response outputs. These inputs allow the engineered circuitry to monitor
external environmental conditions and internal cell state, while the outputs enable the engineered
circuitry to control a range of processes such as metabolism, cell cycle, growth, differentiation, and
synthesis of pharmaceutical products.Science Foundation to create the future of synthetic biology, where
genes, proteins, and cells are snapped together to build living systems.Similar microbial factories could
crank out the costly anti-cancer drug Taxol, synthesized naturally by the Pacific yew tree, or produce a
promising anti-AIDS drug derived from the Samoan mamala tree.Efforts are beginning to engineer
organisms that produce hydrogen, octane, or molecules for alternative energy applications.The Synthetic
Biology researchers are also prototyping a bacterium that eats toxic waste, such as heavy metals.
Keasling is leading the charge to engineer a single-cell soil microorganism, Pseudomonas putida, which
would swim into a pool of pesticides or nerve agents and degrade the chemicals. Another project's goal
is to develop the next-generation of tumor fighting drug delivery systems in the form of a novel microbe.
By artificial redesign, DNA sequences can be generated that is exclusively rational directed by statistical
approaches, or by the favorable combination of different approaches. Design of new biocatalysts
through the redesign of DNA sequences has, for example, significantly impacted medical diagnostics and
therapeutics, as well as industrial biotechnology for pharmaceutical production of chemically interesting
compounds.
Bibliography
http://openwetware.org/wiki/Main_Page
http://www.biobricks.org/
http://www.newscientist.com/channel/life/mg19025521.800-redesigning-life-meet-the-biohackers.html
http://www.plantsci.cam.aco.uk/Haseloff/syntheticbiology/
http://www.theiet.org/publications.journals/synbio/index.cfm
ftp://ftp.cordis.europa.eu/pub/nest/docs/pathfinder_projects_2003-2006.pdf
- Vivek Jaria
(Final Y.B.Pharm.)

We Mean Business!
FAST NEUTRON THERAPY
Introduction:
Fast neutron therapy utilizes high energy neutrons typically greater than 20 MeV to treat cancer. Most fast
neutron therapy beams are produced from proton beams impinging upon beryllium targets.
X-rays produce low LET (Linear Energy Transfer) radiation, and neutrons produce high LET radiation. Because
the electrons produced from X-rays have high energy and low LET, when they interact with a cell typically only
a few ionizations will occur. It is likely then that the low LET radiation will cause only single strand breaks of the
DNA helix. Single strand breaks of DNA molecules can be readily repaired, and so the effect on the target cell
is not necessarily lethal. By contrast, the high LET charged particles produced from neutron irradiation cause
many ionizations as they traverse a cell, and so double strand breaks of the DNA molecule are possible.
Double strand DNA breaks are much more difficult for a cell to repair, and more likely to lead to cell death.
The presence of oxygen in a cell acts a radiosensitizer, making the effect of the radiation more damaging.
Tumor cells typically have a lower oxygen content than normal tissue (hypoxia) and therefore the oxygen effect
acts to increase the sensitivity of normal tissue. Neutron irradiation overcomes the effect of tumor hypoxia,
thus effectively targeting the tumor cells.
Objectives:
The therapeutic objectives of Fast Neutron Radiation are to treat radioresistant tumors like:
GLANDULAR TUMORS SOFT TISSUE TUMORS
• Locally advanced adenocarcinoma • Fibrosarcoma
of the prostate • Liposarcoma
· • Locally advanced squamous cell • Hemangioendothelial sarcoma
carcinoma • Hemangiopericytoma
BONE AND CARTILAGE TUMORS OTHER TUMORS
· • Osteogenic sarcoma • Very large tumors
• Malignant giant cell tumors • Slow-growing tumors
• Inoperable Melanoma
Experimental Techniques:
Following are the summarised techniques:
1) At Harper Hospital, Detroit, fast neutron facility has been setup. Accelerated using super conducting
cyclotron, the beam is produced by the interaction of 48.5 MeV deuteron with beryllium target. The neutron
beam is shaped using a specially developed multi rod tungsten collimator. The time profile of pulsed with a
pulse width of approx 2 ms and a repitation rate of 100 Hz.
2) Development of Compact Proton Linac at Fermilab is the highest energy fast neutron facility, energy being
as high as 1000 GeV. It consists of 4 individual accelerators operating series. The first three form what is
called the “injector” and serve to fill the vacuum chamber of the main accelerator with tightly bunched groups
of 8GeV protons. The main ring in turn increases the energy of the protons. The first three sections of the ninesection
Linac are used to accelerate protons to 66MeV. The protons then drift through tank and are extracted
...contd.
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using two bending magnets. Seven quadrupole magnets and beam position monitoring systems then focus
the beam onto a beryllium target. This collision creates the neutrons with the desired energy for utilization in
the treatment of patients.
3) The Development of a Novel Silicon Microdosimeter for High LET Radiation Therapy.
4) The development of NTF Computer System to ensure safe delivery and the correct amount of radiation to
the patients. Development of software called JCVS system, which controls the amount and rate of radiation
administered to a patient and also maintains a record for easy access.
Mechanism Of Action:
Neutrons interact with matter in a variety of ways depending on their velocity and the nature of the target. The
difference between neutron and electromagnetic radiation is the mechanism by which the incident radiation
interacts with matter. X-rays are scattered by the electrons surrounding atomic nuclei, but the charge neutral
neutrons are scattered by the nucleus itself. Hence, neutrons have very different radiobiological properties.
Tumor cells typically lack effective repair mechanisms, so if radiation is delivered in small sessions, a process
known as fractionation, normal tissue will have time to repair itself.Unlike photons, neutrons are a form of
high linear-energy-transfer radiation (high LET). In the human body, elastic collisions of neutrons with carbon
(C), oxygen (O) or other heavier nuclei cause the nuclei to recoil. Elastic scattering of neutrons with hydrogen
nuclei causes the protons to recoil violently. Since the mass of the proton and other nuclei is so much greater
than that of the electron, when they recoil they generate a much denser ion path that results in more damage
to tissue. High LET radiation usually results in irreparable damage to the exposed cells.
The presence of oxygen in a cell acts a radiosensitizer, making the effect of the radiation more damaging.
Tumor cells typically have a lower oxygen content than normal tissue (hypoxia) and therefore the oxygen effect
acts to increase the sensitivity of normal tissue. Neutron irradiation overcomes the effect of tumor hypoxia.
Conclusion:
Fast Neutron Therapy is a blessing for patients suffering from radioresistant tumors. Therapy has led to easier
and faster cure of such tumors with minimum side effects.
Development of cheaper and safer techniques like Proton Linac Facility, NTS Computer system, JCVS system
has rekindled the interest of scientists in this therapy making it a potential replacement of conventional
radiotherapies and a vast field of research which will decrease the mortality rate and side effects associated
with the radiation therapy drastically.
- Priyank Patel
(Final Y.B.Pharm.)

Tit-Bits
EVERYTHING HAPPENS FOR A REASON
“Live life to the fullest, live like there's no tomorrow.” We must have come across these lines before, they are so
true. Why cry over the past??Why worry about the future??Whatever has to happen will happen, today
tomorrow or day after, there is no stopping it, that's what we call destiny, luck, etc.
Everything happens for a reason, it could be birth, death, illness, love or success. They all carry some
message for us. We find tears in death and a smile in success, these are only our ways of looking at things.
Even the smallest day to day events sculpt us a little more and create a better person out of us.
Sometimes people come in our lives and we know right away that they were there to serve a purpose, teach us
, bless us or help us. Sometimes wrong things happen to us at the wrongest times, but we realise that if not for
those things we would have never succeeded.
Every event, small or big, carries a “reason” along with it. Nothing happens by chance or by luck, whatever
happens is bound to happen and it always happens for the good. Questions like “why did this happened to
me”, “why am I to suffer”, ”why did I lose”,” why did he win”, all have answers and a reason.
“Every man's life is a fairytale, written by GOD'S fingers.”-Hanz Anderson.
“STUD"ent
The garnishings
- Aneri Joshi
(F.Y.B.Pharm.)
Most of us reading this article stay in Mumbai....or at least are studying in Mumbai (because I really think this
magazine is meant for private circulation only.) So....if asked a simple question: "How exactly is the life of a
student in Mumbai???? "What would the possible reply from your side be....well since multiple choice ka
zamana hai I'll give u options....
a) Early morning getting up at round 7:30/8am leaving for college; getting into the 9:30am Goregaon
local, squeezing your way in so that you make sure you are able to get down at the desired station.
Waiting in the lane for a rick; reaching college attending practical's (4 hrs or sometimes 6 hrs).
Running to the canteen; grabbing a bite attending lectures (some of which you just can't understand or
are just not bearable). Then again reaching the station, getting into the train which is packed liked
crazy reaching home and then studying sleeping and then obviously the routine continues......
b) Getting up at 9:30/10am reaching college (obviously dropped by car....so what if there's traffic....).
Checking out whether practical's hai ki nahi or rather are we in time for any of them or not. Going to
the canteen.Eating like you've never eaten before....asking your C.R. “aaj ka time table”. Attending a
lecture or two....then deciding its way too boring ...going to bandstand...chilling out with
friends...then finding out that you are hungry again...going 2 CCD. Eating again (bill????...arre
what's the credit card for???) Then finally deciding aaj ke liye enough and returning home at midnight
maybe, then obviously no more energy left...so sleeping....arre no orkuting then sleeping.
...contd.
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Cutting the crap, bottom line......Is any of the above lives justifiable? Don't you think a balance must be
established between both? Giving equal justice to both, if I may sound clichéd "all work n no play makes jack
a dull boy" So I suppose its up to "Jack" to strike the balance between both...because these are the future
deciding years of our lives also these are the years where we are supposed to explore ourselves as individuals
in society at the same time thoroughly enjoying our youth. So gear up, make a decision and take control of
your life. Achieve something at the same time masti tho karna hi hai. Just thought it's something that you
should think over u know in case u read this article.........
- Pallavi Kolte
(F.Y.B.Pharm.)
When I walked along the absurdly boring chaotic railway platform, the journey seemed to be never ending. It
was the adrenaline flow of returning home from a tiring day at college. Rather I guess that was courtesy
hunger. In relation to the things occurred at college today, there were thoughts in my lonesome mind. I feared
how the scenario would turn out to be at home. It was the first time this had happened after all! I had failed!
Failed in the year of academics! Who was to be blamed? For my sweet consoling friends- it was the biased
system of education running at college.. “the teacher doesn't like you yaar!” , for my teachers- it was my
insincerity... for my parents – it was their daughter with whom their hopes lied in the cardiac muscle [ i.e.; heart
.. come on ! I'm a science student allowed to use the terms], but for me, it was ME! Elaborating every detail
that had happened through the year I went on toward the rickshaw stand, [in the queue the life lies!] I was
scared, unnerved and waiting for one pious moment. “ A failed woman you are miss!” , would be my
interviewer's reaction in future , I thought. “ Do you have suicidal intentions??” , spoke the other thought in my
mind! I shooed it by listening to, “madam, chalna hai na??” , by the rickshaw driver. Finally my den was
approaching. This was the premiere moment where a loser enters home. Using the keys, I got in. I dint want to
delay it anyway so I rushed in. I found my mother and stood in front of her, silently, exasperating. There struck
a strange understanding between us. “Some tea?” , she asked. Denying the offer I moved towards her and
showed her the report card. Filmy moment I felt. But obviously seriousness had creeped in deteriorating that
other comforts in life which I'll have to give up now. This was it! All that I cared about. After a brief moment she
completed going through it carefully. I saw the glimpse of a never happening site. That pearl in her eye. She
came forward and……..hugged me!! I could barely take it! Come on! I had failed! Mom slap me! I was
getting mad!!! I cried too. She looked at me and said the most beautiful words ever. “I never liked studies
myself. I hated examinations. Those yawns during studies haunted me forever. But for you, I had a dream.
With you I wanted excellence. Never stopped you with anything just because I knew, you are destined to shine.
This is not forgiveness, this is encouragement, mind you! Tomorrow I don't want you to miss out on my name in
credits when you achieve that big name. I failed in my first attempt too. If you think failures can't excel and
have no power to do anything, you are mistaken! That thought would have never made me a teacher I am
today! You can do it!
P.S. : Encouragement [not failure] is the stepping stone to success.
- Tanvi Joshi
(F.Y.B.Pharm.)

Tit-Bits
Hallucination
Are we still hallucinating things of the past in front of us or it is just the same old tradition having a toll of dead
people increasing. We people of today by no means are interested in the age old customs and traditions but
knowingly or unknowingly we are still captivated in its clutches. Today as an ordinary human being I do not
intend to revolutionizethesystembutatleast an attempt from the innerpartofusshouldbe made to changethings.
Today India is governed by the government, but the roots of it lie in the religion on which the politician's in way
blackmail or seduce people to join them and if something goes wrong in their plan then as usual riots. People
out here including me become childish on sensitive topics. Today ranking 2nd in the world for population
India still is considered as a backward country and my question to you is why? Are we so dumb that we don't
understand things or are we just neglecting thing so we don't have to worry, the answer to this lies within you
and only you. Common man, right now has an average work in his life of feeding his family, going to work
and of course arrangement for the marriage of their child. Is that it, no more responsibility? Today on an
average half of India's population doesn't vote, the faith on the entire system has been corroded by the corrupt
and useless officer's in the system. Are we blind to see all this or someone has put a blindfold on you. This also
includes me as a matter of fact it also includes the beggars on the street, these people in no way are dumb but
in fact they totally know the internal system and are aware of the happenings, but we people are still in a state
where we have to first decide and then understand, the destiny of our country lies not in the government but in
our hands, it is us who have to stand up at all wrong things in system instead of neglecting it or even getting in to it.
India has big loans on it, on the name of roads, developments and all such things but none of the changes are
seen. All the money is going in the pockets of politician or at the officer at each level of the system. Every year
we see development in our area but literary half of the public doesn't know whether the company is private or
government. Today private companies are expanding more rapidly than the government ones. Even if all the
politician leave corruption for 5 years the dream project of making Mumbai into Shanghai will complete in
seven years.
Speaking of knowledge, half of the US companies are picking up their top executives from India. Indian
people go to US, earn money take a green card and settle there and all the useful knowledge becomes a
waste for India and the reason to this is the educational system in India. Why are there reservations? Why are
there castes and tribes? If you want results and brilliant minds, the reservation will just destroy them. Truly
speaking all the seats of higher educational colleges should be given on merit, those who want it will have to
work for it. Why should some people be favored, are they great men or what? Or are they descendent of
Einstein. Now it is high time in India when people start thinking of the future of the country and not waste time
on discussing that things going around are wrong or discussing age old news and commenting whether they
were right or wrong. India doesn't need an improved government but improved human beings who are willing
to participate everything for the development of the country. The deeper you go to find out the truth of India
the more you will be hurt. These politicians are not only playing with your emotions but are robbing out of you
your confidence, your talent and everything. We often feel depressed after getting an average score in some
university exam and the first thing that comes to people who are of open category that whether they will get
admission or not, why is the system so bad, why are there reservations and stuff? Today the only disgust in the
people of open category is why there are reservations? The people of open category think that being an open
category they have done a crime and the reservations are not for SC, ST, OBC but they are for open category
- Paras Shah
(F.Y.B.Pharm.)
44

45
WITH BEST COMPLIMENTS FROM
MR. A. A. NADIADWALA
&
MR. FIROZ A. NADIADWALA

OM SAI RAM
With Best Compliments From
SUPER DYNIC CLOTHING PVT. LTD.
337, BADAMWADI, 2ND FLOOR,
KALBADEVI ROAD,
MUMBAI - 400 002
TEL.: 022-2241 5578, 2240 6487
FAX: 022-2240 6920
E MAIL: superspun@vsnl.net
WE ARE MANUFACTURER & EXPORTER OF
COTTON TERRY TOWELS,
HOME FURNISHING & BATH LINEN.
46

47
With Compliments
From
BW Shipping Managers Pte Ltd
(The BW Group is one of the world’s leading maritime groups.)
Address:
841, Solitaire Corporate Park
167, Guru Hargovindji Marg,
Chakala, Andheri East
Mumbai – 400093
Tel – 022-28370101/66751011
Fax – 022- 66959564
E-mail – general.india@bwshipping.com
Website – http://www.bwshipping.com
WE HAVE WIDE RANGE OF DESIGN FOR YOU TO CHOOSE FROM.
OUR FURNITURE CREATES SOUL,
WITHOUT WHICH A HOME IS INCOMPLETE.

With Best Compliments From
UNITECH UNITECH TRANSFORMATION
TRANSFORMATION
PVT. LTD.
1/ 41, 42 Bhandup Industrial Estate,
Pannalal Silk Mill Compound,
L.B.S. Marg,
Mumbai - 400 078.
Tel.: (022)-2596 8473/ 2596 4278.
Fax: (022) 2596 8357.
E-mail: unitrans@mtnl.net.in
PETER’S MEDICAL
& GENERAL STORE
55/D, Ramnath Prasad Bldg., Dr. Ambedkar Road,
Danpada Junction, Khar Danda, Khar (W), Mumbai - 400052
Tel.: 69524963, 69918610
48

49
With Best Compliments From
KAUSHAL EQUIPMENT MANUFACTURERS
Office / Works:
22, Sardar Pratap Singh Ind. Estate,
No.3, L.B.S. Marg,
Bhandup (W), Mumbai - 78.
Works:
Plot No. R-38,
T.T.C. Industrial Area Rabale,
Thane-Belapur Road.
E-mail: manvir@kaushalindustries.com
Website: www.indiamart.com / kaushalindustries
WITH WITH BEST COMPLIMENTS COMPLIMENTS FROM FROM
GTC Industrial Limited,
Tobacco House, S.V. Road,
Vile Parle (W), Mumbai -400 056

Page 3 Glitterati
IPA Students’ Cell Members
(L to R): Forum Sanghvi, Mihir Shah, Siddharth Wagal, Jigar Shah, Tanay Surkund, Neha Kotak
Industrial Visit to GOA
Students of T.Y.B.Pharm. outside UNICHEM Labs with Mrs. Bhagyashree Joshi & Mrs. Bhavana Patel
50

51
Page 3 Glitterati
Final Year B.Pharm.
Final Year D.Pharm.

Non-Teaching Staff
Standing (L to R): Mr. Santosh Bhure, Mr. Mahendra Survey, Mr. Ghanshyam Kambli, Mr. Yuvray Thakare,
Mr. Appa Patade, Mr. Dattaram Bhure, Mr. Nilam Gawde, Mr. Prashant Rane,
Mr. Pradeep Jadhav, Mr. Anil Chauvan, Mr. Vivek Pednekar, Mr. Shailip Salaskar, Mr. Ajay Mali,
Mr. Sanjay Katkar, Mr. Vijay Gawde, Mr. Milind Damle, Mr. Sunil Mohite
Sitting (L to R): Ms. Manisha Barve, Ms. Usha Bansode, Mr. S. D. Bhosale, Dr. U. B. Hadkar,
Dr.(Mrs.) Abha Doshi, Ms. Manasi Vaidya, Ms. Priya Sawant, Ms. Manisha Alat
We sincerely thank
Mr. J. G. Irani, Mr. Nikhil Duble, Mr. Ashish Shrivastava (MET MARCOM)
Mr. Nitin Patil, Ms. Vidya Joshi (MET Design)
Rakesh Jain (Final Y.B.Pharm.)
Ankur Agarwal (Final Y.B.Pharm.)
Pooja Nagori (Final Y.B.Pharm.)
Abhijeet Lad (T.Y.B.Pharm.)
Divija Pathak (T.Y.B.Pharm.)
Shraddha Shinde (S.Y.B.Pharm.)
Amruta Mane (F.Y.B.Pharm.)
Paras Shah (F.Y.B.Pharm.)
Vaibhav Jain (F.Y.B.Pharm.)
Rushil Bhatt (F.Y.B.Pharm.)
Last but not the least the IOP staff and IPA members from our college
who constantly helped and supported us.
52

53
The Victorious
The Trophies
(L to R): Rx Winners Sports Trophy, Rx Winners Best College Trophy,
Rx Runners-up Cultural Trophy, Rx Winners Dance Trophy
Celebrations
...after Rx!

La Fête
The Events & Winners!!!

MET Institute of Pharmacy
MET League of Colleges | Mumbai Educational Trust
MET Complex, Bandra Reclamation, Bandra (W), Mumbai 400 050.
Tel: ( +91 22 ) 2644 0446 | Telefax: 2644 0093 | Toll-free: 1800 22 0234
email: communications@met.edu | www.met.edu
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MET is an NGO in Special Consultative Status with United Nations (ECOSOC)