05.04.2013 Views

GHENT UNIVERSITY Karoline FONCK - International Centre for ...

GHENT UNIVERSITY Karoline FONCK - International Centre for ...

GHENT UNIVERSITY Karoline FONCK - International Centre for ...

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

eing single, ever having been treated <strong>for</strong> an STD, pregnancy, an uncircumcised partner,<br />

and ever having used a condom. After multivariate analysis including all these variables, only<br />

the number of partners in the previous 3 months (P = 0.02) and an uncircumcised partner (P<br />

= 0.01) remained statistically significant.<br />

Table 4 : Odds Ratios and 95% Confidence Intervals (CI) <strong>for</strong> risk factors and sexually transmitted infections*<br />

HIV Gonorrhea Chlamydia Syphilis CIN<br />

Single/widow/divorced/separated 1.1 (0.7-1.8) 1.8 (0.7-4.7) 1.9 (0.7-5.4) 0.8 (0.3-2.0) 0.8 (0.4-1.5)<br />

History of STD 1.1 (0.7-1.8) 0.9 (0.4-2.3) 0.2 (0.1-1.1) 2.1 (0.9-4.7) 2.2 (1.2-4.0)*<br />

History of condom use 1.5 (1.0-2.3) 2.2 (0.9-5.3) 1.6 (0.6-4.1) 2.3 (1.0-5.4) 1.2 (0.7-2.2)<br />

Younger than 20 years 0.8 (0.4-1.6) 0.9 (0.3-3.3) 2.6 (0.8-8.7) 1.6 (0.5-4.6) 1.6 (0.7-3.8)<br />

Age at first sex < 15 years 1.5 (0.9-2.3) 0.9 (0.4-2.5) 0.2 (0.0-0.9)* 1.4 (0.6-3.5) 0.9 (0.4-1.7)<br />

>One sex partner last 3 months 2.3 (1.1-4.8)* 5.6 (1.7-18.2)* 3.5 (0.9-13.2) 1.0 (0.3-3.2) 1.3 (0.5-3.5)<br />

>= 1 new sex partners (3 months) 0.8 (0.4-1.7) 2.1 (0.4-3.5) 0.7 (0.2-2.9) 3.8 (1.3-10.9)* 0.9 (0.3-2.2)<br />

Partner circumcised 0.5 (0.3-0.9)* 2.2 (0.7-6.7) 0.6 (0.2-2.0) 0.9 (0.3-2.6) 0.9 (0.4-1.9)<br />

Pregnant 0.7 (0.4-1.1) 1.1 (0.4-2.8) 2.4 (0.9-6.7) 1.4 (0.6-3.4) 1.0 (0.6-1.9)<br />

Bacterial<br />

vaginosis<br />

Trichomonas Candida<br />

Genital<br />

ulcer<br />

Genital<br />

warts<br />

Single/widow/divorced/separated 1.9 (1.0-3.8) 1.5 (0.8-2.8) 1.1 (0.7-1.7) 1.3 (0.7-2.4) 1.4 (0.6-3.3)<br />

History of STD 0.6 (0.3-1.2) 0.8 (0.4-1.5) 1.1 (0.7-1.8) 1.1 (0.6-2.0) 1.3 (0.6-3.2)<br />

History of condom use 1.4 (0.7-2.5) 1.4 (0.8-2.4) 0.8 (0.5-1.1) 1.3 (0.8-2.3) 0.7 (0.3-1.6)<br />

Younger than 20 years 0.7 (0.2-1.8) 0.8 (0.3-1.8) 0.6 (0.3-1.2) 1.2 (0.5-2.7) 3.2 (1.2-8.1)*<br />

Age at first sex < 15 years 0.7 (0.4-1.5) 1.1 (0.6-2.1) 1.2 (0.8-1.9) 1.8 (1.0-3.3) 0.7 (0.3-1.9)<br />

>One sex partner last 3 months 1.9 (0.7-5.1) 1.6 (0.7-3.7) 0.9 (0.4-1.9) 1.4 (0.5-3.8) 0.8 (0.2-3.2)<br />

>= 1 new sex partners (3 months) 0.6 (0.2-1.5) 1.3 (0.6-2.9) 0.8 (0.4-1.5) 0.6 (0.2-1.5) 1.1 (0.3-3.6)<br />

Partner circumcised 1.4 (0.6-3.3) 1.1 (0.5-2.2) 0.6 (0.4-1.0) 1.5 (0.8-3.2) 0.7 (0.3-1.8)<br />

Pregnant 0.7 (0.4-1.4) 1.7 (1.0-3.1) 1.5 (1.0-2.3) 0.6 (0.3-1.2) 2.1 (0.9-4.9)<br />

All Odds ratio adjusted <strong>for</strong> age, marital status, history of STD, history of condom use, age at first sex, number of sex partners<br />

and circumcision of partner.<br />

* P< 0.05<br />

** Among 520 female patients, Nairobi, Kenya<br />

The only risk factors <strong>for</strong> gonococcal infection was the number of sex partners in the last 3<br />

months (P = 0.001). Women with chlamydial infection had significantly less history of first<br />

sexual intercourse when younger than 16 years (P = 0.04). RPR seroreactivity was<br />

associated in univariate analysis with the number of sex partners, having had a new sex<br />

partner, and ever having been treated <strong>for</strong> STD. After multivariate analysis including those<br />

variables, only having a new partner in the last 3 months remained statistically significant.<br />

The only factor associated with CIN was history of an STD (P = 0.03). Bacterial vaginosis,<br />

trichomonas infection, candidiasis, and genital ulcers were not associated with any of the risk<br />

factors. Young age was strongly associated with presence of genital warts in multivariate<br />

analysis (P = 0.007).<br />

PREVALENCE AND RISK FACTORS OF STI 28

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!