Investigating CSI – Background material Table of Contents I ...

However, if both parents were heterozygous, they could have children with any of
the three genotypes, though heterozygous children would be twice as likely as
either of the homozygous genotypes.
With increasing genomic sequence information, increasing numbers of genetic
disease can be predicted from RFLP analyses.
Genetic Mapping
To calculate the genetic distance between to loci, you need to be able to observe
recombination. Traditionally, this was performed by observing phenotypes but
with RFLP analysis, it is possible to measure the genetic distance between two
RFLP loci whether they are a part of genes or not.
Let's look at a simple example in fruit flies. Two RFLP loci with two RFLP bands
possible at each locus:
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