Reversible Cerebral Vasoconstriction Syndromes (RCVS)
Reversible Cerebral Vasoconstriction Syndromes (RCVS)
Reversible Cerebral Vasoconstriction Syndromes (RCVS)
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<strong>RCVS</strong><br />
• Group of conditions characterized by reversible<br />
segmental constriction-dilatation of cerebral arteries<br />
• ~90% have recurrent ‘thunderclap’ headaches<br />
• Brain MRI can be normal or show ischemic stroke,<br />
ICH, cSAH, or reversible brain edema (PRES)<br />
• Usually a self-limited condition with benign outcome<br />
• Angiographic reversal occurs within days to weeks<br />
• Pathophysiology: ?abnormal cerebral vascular tone<br />
Singhal et al., Arch Neurol 2011; Calabrese et al., Ann Int Med 2007;<br />
Ducros et al., Brain 2007; Chen et al., Ann Neurol 2008, 2010