02.04.2013 Views

Reversible Cerebral Vasoconstriction Syndromes (RCVS)

Reversible Cerebral Vasoconstriction Syndromes (RCVS)

Reversible Cerebral Vasoconstriction Syndromes (RCVS)

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<strong>RCVS</strong><br />

• Group of conditions characterized by reversible<br />

segmental constriction-dilatation of cerebral arteries<br />

• ~90% have recurrent ‘thunderclap’ headaches<br />

• Brain MRI can be normal or show ischemic stroke,<br />

ICH, cSAH, or reversible brain edema (PRES)<br />

• Usually a self-limited condition with benign outcome<br />

• Angiographic reversal occurs within days to weeks<br />

• Pathophysiology: ?abnormal cerebral vascular tone<br />

Singhal et al., Arch Neurol 2011; Calabrese et al., Ann Int Med 2007;<br />

Ducros et al., Brain 2007; Chen et al., Ann Neurol 2008, 2010

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