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A quick reference guide to haemofiltration and renal failure March ...

A quick reference guide to haemofiltration and renal failure March ...

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CRRT, or continuous <strong>renal</strong> replacement therapy, is any<br />

extracorporeal blood purification therapy intended <strong>to</strong> substitute<br />

for impaired <strong>renal</strong> function for an extended period of time, <strong>and</strong><br />

intended <strong>to</strong> run over 24 hours a day. (Bellomo, Ronco <strong>and</strong> Mehta, 1996:S3)<br />

CRRT is indicated for several reasons in the intensive care unit<br />

(ICU). Some of these indications are;<br />

Renal Failure, Diuretic-resistant pulmonary oedema,<br />

De<strong>to</strong>xification, Severe hepatic <strong>failure</strong> <strong>and</strong> Sepsis.<br />

Criteria for the initiation of dialytic therapy will depend upon the<br />

treating physician, but general criteria include oliguria, anuria,<br />

plasma urea concentration >35mmol/l, serum creatinine<br />

concentration >600umol/l, hyperkalaemia >6.5mmol/l, pulmonary<br />

oedema non-responsive <strong>to</strong> diuretics, metabolic acidosis (pH

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