Notice of Hearing on the Application to Use Sodium Fluoroacetate ...

. 7 hi~her
1G60 resiaups :ban :vera found jn any coyote killed by punczilrjng
i. " . - t
~3xi c C C Izr, ~ 90 ;\/i G O ~ C GT ~ 7 nc,3;i1 ci;i 39 ',/as ' aaszr-~ad. , , qqrz is
8 .
2videnc~ cnat foxss c:ed 2fxr i.ed?ng on vangaroo ra?: scisoned by
1080 used as a rocen~jcide 2nd chaz iOyQE2S digd aftsr faeding an
ground squirrels poisoned by oats treat2d with 1030. Neverxheless,
the FWS tests constitute substantial evidence that the risks <strong>of</strong>
secondary poisoning to non-target wildlife f~en use <strong>of</strong> the coxic
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collar are not signiiicant.
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3 . The citric acid or Xrsb cycle is the final mechanjim fgr converting
food into energy in plants and animals. Sodium fluoroacetate, ;vh~n
ingested, i i metabolized into fl~oroci trax, :vhich inhi bi~i actlviiy
<strong>of</strong> ;he enz,me aconi ~ ase and deprives ~311 s <strong>of</strong> energy. This enzyme
inhibition resuits in tne blocking <strong>of</strong> the YrcS cycle, einicn sec3ndarib
blocks glucose metaboiizm, a lesser ecery ~rgducin~ process. 3;ockage
<strong>of</strong> chese proc2sses causes the er,er?y supplid LO be red~c2d to tne
point nhera cel1u:ar peneabilizy barriers aro destroyed, resulying
in loss <strong>of</strong> function and finally ce1lu:ar death. The breakdown in
intracellular processzs eventually rgsultj in the aopearanc? <strong>of</strong>
gross organ or organ system disorders. Death nay result from gr~dual
cardiac failure or ventricular iibri 11 ation, or progressive depression
<strong>of</strong> the central nervous system with either cardiac or respiratory
8/ Defenders emphasize the latency period from the time <strong>of</strong> ingestion
<strong>of</strong> log0 to the onset <strong>of</strong> toxic effects and the tendency <strong>of</strong> poisoned aniaal z
to hide an reasons why a19 animal5 and birds - goisoned by 1080 bait stat'ovs
wlae uii; 7 kelj LCI 02 T oknu &rid repi)! tra, I nese facts wou i a ai so seem .eo make
it less likely that the carcasses sf poisoned birds and animals would be
available to scavengers.