Notice of Hearing on the Application to Use Sodium Fluoroacetate ...

136
and ;ha. for a scls2n eagle is 1,25 tg 5.C0 -x/t,. J.
(7;
-1 .
5 -P4, 2--
1 tu I Su i;s
1.5 g <strong>of</strong> 1080 per 160 pounds <strong>of</strong> bait, thac a i50-pound man wauid
obtain an LD5g by the consumption <strong>of</strong> from 47.6 oz -LO 142.3 oz and
that a gol'den eagle (average weight 7 pounds) wouid recsive an LDS0
by consuming from 4.0 oz co i5.9 oz <strong>of</strong> such bait macerial. An LDlgO
for a coy0t2 has been estimated 3t 0.16 ~~g/kg. ic is zcparsnt tha;
- values fcr nan and the 23912 as neil as scter s?ecifs ar?
the LDcO
not precise and have a cgnsiderable ranee. - 12szs so 2stablish :hese
values have obviously not been csnducted on humans 3nd Tne xsts 3r1
many other species including coyots and eac12s have not wen
conducted on a sufficient number <strong>of</strong> 3ninals cha~ a staciszjczl
coniidence interval can oe zstablished. Inasmuch as the fcod
consurnprion <strong>of</strong> an eagle is approximatoi y h o pounds a day, L i i
clear that an eagle could obtain a potentially lethal dose in feeding
on 3 bait station. This is, <strong>of</strong> course, also true <strong>of</strong> cther ncn-carget
sgecies. There is evidence that the $350 valu? can vary depending
on whether the god? gf administration is by a tallow bait or water.
Moreover, Drs. Buck and Seasley (finding 184) referred to a study
indicating that a median lethal dose <strong>of</strong> 1080 ac 22°C was 21 mg/kg,
while at 8OC, the equivalent dose was 4.5 mg/kg, indicating that
temperature had a great effect on the toxicity <strong>of</strong> the poison. LDjO
values are more likely to have been establ i ined in laboratori?~ at
or near normal room temperatures.