Notice of Hearing on the Application to Use Sodium Fluoroacetate ...

, r,no,rz z-Q?~ 53 352 '32; ~5 7 y zz3;ii?shi3 csnr2.l n i v gm-?rc;:j--a'_-l~
1,3 g cf 1CSO cr sli~nsly less :mn the 1.5 crms 39r 130 ~ O U ~ SUSC~C S
in a ? arge s cati cn. 'Aycni ng ' s appl i caci ;n apparenciy i qtsn~s chat th?
amount <strong>of</strong> 1280 in eacn bait as well as the maximum applicaricn raz2
be left to the judgmen?: <strong>of</strong> the applicators. 9r. :iiliiam suck, Pr<strong>of</strong>essor
<strong>of</strong> Vezerinary Toxicology and Director <strong>of</strong> the Animal Poison Cantroi
Center, Gniversity <strong>of</strong> Illinois, lirbana and Dr. '/a1 I?. B2?sl9y, 20ct~r
<strong>of</strong> Vetari nary Xedicine and Research ,Asscci ate in Toxicoic~y a: the
University <strong>of</strong> I1 1 inois , w i tness3s for Deflndzrs , kstified :?a: Secause
SLDs wer2 designed for more widespread use, chey were mcr2 iikoly co
be more availabls to domestic dogs and cats and use <strong>of</strong> SLDs could
result in the poiscning <strong>of</strong> large numbers <strong>of</strong> thesz and other snail
non-target carnivores. Dr. Buck acknowledged, however, rhat a requi rz-
menc tnat baits be placed no nearzr than a ~i 3 e or mo from 2 home or
occupied dwei 1 ins would 1 esszn the nazara co nese animals.
185. The contzntion that Compcund 1C8C is a sel~ctivs poisan is bas& in
?rinci?al par: on differing levei s <strong>of</strong> s2nsi tivi ty 10 rho, joison.
Carniiores .rp_ in general Tore sensitive to 1030 than a;her s jet! es,
while canines are considerzd :o be 2speciaIiy susceptible theraf3.
- 23/
For example, the LD50 <strong>of</strong> 1080 for a coyotg has keen determined tc
be 0.10 mg/kg, whils that for a man is estimated at 0.7 to 2.1 mg/kg
23/ An LD50 value is a statistical estimate <strong>of</strong> the dosage that would
be letxal to 50 percent <strong>of</strong> animals t2sted.