M.Sc Syllabus - Andhra University, Visakhapatnam

AC 304 : DRUGS AND DYES
DRUGS – I Introduction - classification – chemotherapeutic agents –
pharmacodynamic agents – Definition of the terms commonly used in the
chemistry of drugs – Definitions of the terms commonly used in the chemistry of
drugs (pharmacy, pharmacology, pharmacodynamics, pharmacopore,
pharmacodynamic agents Metabolites and Antimetabolites, Therapeutic Index)-
Structure & Physiological activity relationship, Assay of drugs (chemical assay).
ANTIBIOTICS Chemical structures , methods of production and medical uses of
pencillin, streptomycin, chloramphenicol, Tetracyclines.
STRUCTURES AND SYNTHESIS OF THE FOLLOWING TYPES OF DRUGS
(Non – structural Streatment only):
SULPHONAMIDES Sulphanilamide, sulphapyridine, sulphathiazole (cibazole),
sulphadiazine, sulphamerazine, sulphaguanidine, sulphisoxazole,
sulphapyrazine, Marfanil (sulphamylon). Mechanism of action of sulpha drugs.
ANTIPROTOZOAL AGENTS Diodoquine Carbarsone
ANTISEPTICS Chloramine- T (chlorozone ), Thymol, Dichloramine- T ,
Iodoform, Dettol, Mandelic acid , Urotropine.
DRUGS – II
STRUCTURE AND SYNTHESIS OF THE FOLLOWING TYPES OF DRUGS
(Non – structural treatment only)
ANTILEPROTIC DRUGS Dapsone (DDS), Acedapsone (DADDS)Chaulmoogra
and Hydrocarpus oil .
ANTI CANCER AGENTS Alkylating agents.
MUSTARDS Melphalan, chlorambucil, Amethopterin.
ANAESTHETICS Benzocaine, pentothal sodium
SEDATIVES , HYPNOTICS and ANTICONVULSANTS (anti epileptics )
Bromural, Barbiturates (veronal ), phenobarbitone, Hydental.
TRANQUILISERS Chloropromazine, Diazepam, Hydroxyzine (atarax ), pipradol
(meratran ).
CARDIOVASCULAR DRUGS Amyl nitrate, Methyldopa.
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