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Use of nasal and buccal cells in human biomonitoring ... - Formacare

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siegfried.knasmueller@meduniwien.ac.at<br />

Historical notes<br />

• Micronuclei were discovered by Schmid <strong>in</strong> 1972.<br />

• The first experiment with exfoliated <strong>cells</strong> was conducted by<br />

Stich <strong>and</strong> Parida <strong>in</strong> 1982.<br />

• The first FA study with <strong>nasal</strong> <strong>cells</strong> was published <strong>in</strong> 1992 by<br />

Ballar<strong>in</strong> et al.<br />

• A review on the effects <strong>of</strong> FA <strong>in</strong> exfoliated <strong>cells</strong> appeared <strong>in</strong><br />

2006 (Speit et al.)<br />

• In 2004 the HUMN xl consortium was formed (M. Fenech, E.<br />

Zeiger, N. Holl<strong>and</strong>, C. Bolognesi, S Burgaz, S. Knasmüller)<br />

<strong>and</strong> started to evaluate <strong>and</strong> st<strong>and</strong>ardize MN experiments<br />

with exfoliated <strong>buccal</strong> <strong>cells</strong>.<br />

7

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