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Use of nasal and buccal cells in human biomonitoring ... - Formacare

Use of nasal and buccal cells in human biomonitoring ... - Formacare

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Not all endpo<strong>in</strong>ts are related to cancer risks !!!!<br />

• MN <strong>in</strong> lymphocytes <strong>and</strong> <strong>buccal</strong> <strong>cells</strong> reflect<br />

<strong>human</strong> cancer risks.<br />

• Chromosomal aberrations <strong>in</strong> lymphocytes<br />

correlate with <strong>human</strong> cancer risks.<br />

• Sister chromatid exchanges <strong>in</strong> lymphocytes: no<br />

correlation.<br />

• Comets: not known !!!!!<br />

• DNA Adducts: for certa<strong>in</strong> adducts clear<br />

associations were established.<br />

• OHdG <strong>in</strong> ur<strong>in</strong>e <strong>and</strong> lymphocytes: not known.<br />

siegfried.knasmueller@meduniwien.ac.at<br />

4

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