Use of nasal and buccal cells in human biomonitoring ... - Formacare
Use of nasal and buccal cells in human biomonitoring ... - Formacare
Use of nasal and buccal cells in human biomonitoring ... - Formacare
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siegfried.knasmueller@meduniwien.ac.at<br />
Comments II<br />
• The results <strong>of</strong> the rema<strong>in</strong><strong>in</strong>g studies are controversial; none <strong>of</strong><br />
them fulfills the criteria for optimal <strong>in</strong>vestigations<br />
• Ladeira et al (2011) <strong>and</strong> also Viegas et al (2010) conducted<br />
relatively large studies; they evaluated 2000 <strong>cells</strong> <strong>and</strong> used<br />
Feulgen without counter sta<strong>in</strong>.<br />
• All other studies were smaller as suggested <strong>and</strong> <strong>in</strong> some <strong>of</strong><br />
them the number <strong>of</strong> evaluated <strong>cells</strong> was below 2000 (Holl<strong>and</strong><br />
et al, 1996, Zeller et al, 2011).<br />
• In none <strong>of</strong> the FA studies published so far nuclear anomalies<br />
other than MN were evaluated.<br />
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