Use of nasal and buccal cells in human biomonitoring ... - Formacare

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siegfried.knasmueller@meduniwien.ac.at Staining a b c Figures a and c depict May-Grünwald-Giemsa stained cells. Figures b and d show the same cells after staining with Feulgen and DAPI. d A large number of earlier studies used DNA unspecific stains (e.g. Giemsa) which lead to false positive results (as they stain keratin bodies that are formed in epithelial cells as a consequence of cytotoxicity. Nersesyan et al. Cancer Epidemiol Biomarkers Prev 2006;15(10). October 2006 14
siegfried.knasmueller@meduniwien.ac.at Slide preparation • Optimal slide preparation is achieved by use of a cytospin. • Direct smears will lead to „low quality slides“ that are hard to evaluate. 15
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Page 3 and 4: siegfried.knasmueller@meduniwien.ac
Page 5 and 6: Not all endpoints are related to ca
Page 9 and 10: Different types of nucelar aberrati
Page 11 and 12: Nat Protoc. 2009;4(6):825-37. 2009
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Page 17 and 18: Number of participants requested si
Page 19 and 20: Methodological aspects: experiments
Page 27 and 28: Chicken manure B: ─ / N ─ Studi
Page 29 and 30: Which cell types are more sensitive
Page 31 and 32: FA studies with exfoliated cells
Page 33 and 34: Micronucleus frequencies in exfolia

Use of nasal and buccal cells in human biomonitoring ... - Formacare

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