DSM+II+1968

18 MENTAL DISORDERS
Glucogenosis (Von Gierke's disease). Due to a deficiency in glycogenmetabolizing
enzymes with deposition of glycogen in various organs,
including the brain.
Hypoglycemosis. Caused by various conditions producing hypoglycemia
which, in the infant, may result in epilepsy and mental defect.
Diagnosis may be confirmed by glucose tolerance tests.
.3 Associated with gross brain disease (postnatal)
This group includes all diseases and conditions associated with neoplasms,
but not growths that are secondary to trauma or infection. The
category also includes a number of postnatal diseases and conditions
in which the structural reaction is evident but the etiology is unknown
or uncertain, though frequently presumed to be of hereditary or familial
nature. Structural reactions may be degenerative, infiltrative, inflammatory,
proliferative, sclerotic, or reparative.
Neurofibromatosis (Neurofibroblastomatosis, von Recklinghausen's
disease). A disease transmitted by a dominant autosomal gene but
with reduced penetrance and variable expressivity. It is characterized
by cutaneous pigmentation ("cafe au lait" patches) and neurofibromas
of nerve, skin and central nervous system with intellectual capacity
varying from normal to severely retarded.
Trigeminal cerebral angiomatosis (Sturge-Weber-Dimitri's disease).
A condition characterized by a "port wine stain" or cutaneous angioma,
usually in the distribution of the trigeminal nerve, accompanied
by vascular malformation over the meninges of the parietal and occipital
lobes with underlying cerebral maldevelopment.
Tuberous sclerosis (Epiloia, Bourneville's disease). Transmitted by
a dominant autosomal gene, characterized by multiple gliotic nodules
in the central nervous system, and associated with adenoma sebaceum
of the face and tumors in other organs. Retarded development and
seizures may appear early and increase in severity along with tumor
growth.
Intracranial neoplasm, other. Other relatively rare neoplastic diseases
leading to mental retardation should be included in this category
and specified when possible.
Encephalopathy associated with diffuse sclerosis of the brain. This
category includes a number of similar conditions differing to some
extent in their pathological and clinical features but characterized