Genomics – A New Era for Cattle Breeding. Session - ICBF

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SNP haplotype to MS allele BM1824 Imputated Allele Haplotype Brown Swiss Guernesy Holstein Jersey Overall BABBAABBAAAABBBAABABABBBABBBAAAB 178 178 178 178 178 BAABAABBAAAABBBAABABABBBABBBAAAB 178 178 BBBBAABBAAAABBBAABABABBBABBBAAAB 178 178 BABBAABBAAAABBBAABABABBBAABBBBAB 178 178 BABBAABBAAAABBBAABABABBBABBBAABA 178 178 BAABBAABBAAABBBAABABABABABBBAAAB 178 178 BAABABABBAAABBAABAABABBBABAAAABA 180 180 BAABABABBAAABBAABAABABBBABBBAAAB 180 180 AABBAABBBAAABBAABAABABBBABBBAAAB 180 180 AAAABAAABBABBAAABAABABABABAAAAAB 180 180 180 AAAABAAABBABBAAABAABABABABAAAABA 182 182 182 182 182 AAAABAAABBABBAAABAABABABABAAAAAA 182 182 BAABBAABBBABBBAABBABABABABABAAAA 182 182 AAAABAAABBABBAAABAABABABABABAAAA 182 182 BABBAABBAABAABBBBBBABAAABABBBBAB 182 182 BAAABABBAABAABBBBBBABAAABABBBBAB 188 188 BAABAABBAABAABBBBBBABAAABABBBBAB 182 188 182_188 AABBAABBAABAABBBBBBABAAABABBBBAB 188 188 188 AAAABABBAABAABBBBBBABAAABABBBBAB 188 188 188_190 188_190 188_190 17% MS-SNP haplotypes identical across >2 breeds
Validate <strong>Cattle</strong> with SNP and MS on self or parent Brown Swiss= 71 Guernsey= 60 Holstein= 1110 Jersey= 60
Page 1 and 2: Genomics - A New Era for Cattle Bre
Page 3 and 4: Session 1. Genomics & parentage ide
Page 5 and 6: Introduction to Animal Breeding & G
Page 7 and 8: Traditional Animal Breeding • Cal
Page 9 and 10: Using technology of today • At bi
Page 11 and 12: How do we use this DNA information?
Page 13 and 14: What is a SNP? • 99.9% of human D
Page 15 and 16: SNP effect on performance SNP Var M
Page 17 and 18: Indentifying Mendelian sampling ter
Page 19 and 20: Cost of sequencing has decreased Bu
Page 21 and 22: Sire …..TCACCGCTGAG….. …..CAG
Page 27 and 28: Parentage Sire 1 Sire 2 Sire 3 Sire
Page 29 and 30: Recessive genetic disorders AB AB A
Page 31 and 32: To Conclude • Differences seen be
Page 33 and 34: Genomic Advances in Parentage Verif
Page 35 and 36: U.S. Department of Agriculture, Agr
Page 37 and 38: Blood Typing >1990’s Used to dete
Page 39 and 40: Used to detect bi-allelic polymorph
Page 41 and 42: Technology Transfer via Imputation
Page 43 and 44: Impute ISAG cattle MS alleles from
Page 45: SNP haplotype to MS allele BM1824 I
Page 49 and 50: Validate Phase, impute, check 316 S
Page 51 and 52: Validate Phase, impute, check 316 S
Page 53 and 54: Validation with DAIRY table Order:
Page 55 and 56: Microsatellite Imputation 2 nd Stud
Page 57 and 58: Initial Results 642 456 312 233 220
Page 59 and 60: Acknowledgements • BFGL (USDA-ARS
Page 61 and 62: Parentage verification Genomic sele
Page 63 and 64: LD+ content (V1-19K) • Genomic se
Page 65 and 66: Proportion allele concordance 1.00
Page 67 and 68: • CVM • BLAD Lethal Recessives
Page 69 and 70: Major genes • 14 major genes incl
Page 71 and 72: From just 1 hair sample! Calf ID CV
Page 73 and 74: Conclusions • Custom chip - value
Page 75 and 76: Implementation of Genomic Services
Page 77 and 78: What is Genotyping? • Identifying
Page 79 and 80: Typical example of processing a Bov
Page 81 and 82: ICBF & Teagasc Genomics Conference
Page 93 and 94: Work Flow Summary • Sample assign
Page 95 and 96: IRISH CATTLE BREEDING FEDERATION Ge
Page 97 and 98:
© Irish Cattle Breeding Federation
Page 99 and 100:
User friendly, fully integrated, tr
Page 101 and 102:
AI Company/Breed Society Order Scre
Page 103 and 104:
HerdPlus® User genotype request sc
Page 105 and 106:
Page 107 and 108:
Page 109 and 110:
Page 111 and 112:
VIEW YOUR RESULTS Genomic Evaluatio
Page 113 and 114:
Page 115 and 116:
Chip Type Number of animals genotyp
Page 117 and 118:
LIST OF BEEF BULLS WANTED Contact I
Page 119 and 120:
Page 121 and 122:
Genomics & Breeding Programs • Ge
Page 123 and 124:
Pedigree dairy registrations (2011)
Page 125 and 126:
Moving Beef to SNP’s for parentag
Page 127 and 128:
Moving beef industry to SNP’s for
Page 129 and 130:
Quantifying the Benefits. A quick s
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Genomics – A New Era for Cattle Breeding. Session - ICBF

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