Genomics – A New Era for Cattle Breeding. Session - ICBF

More documents

Recommendations

Info

IRISH CATTLE BREEDING FEDERATION Role of Genomics in Irish Dairy and Beef Breeding Programs. Part I. Parentage Verification. Andrew Cromie, ICBF. 12 th November 2012. © Irish Cattle Breeding Federation Soc. Ltd 2009 120
Genomics & Breeding Programs • Genetic improvement (€); – Quality & quantity of data (ID, ancestry & performance). – Profit based genetic indexes (EBI & €uro-Stars), – Selecting the best to breed the next generation. • Focus on two areas; (i) parentage verification and (ii) genetic gain. 121
Page 1 and 2:
Genomics - A New Era for Cattle Bre
Page 3 and 4:
Session 1. Genomics & parentage ide
Page 5 and 6:
Introduction to Animal Breeding & G
Page 7 and 8:
Traditional Animal Breeding • Cal
Page 9 and 10:
Using technology of today • At bi
Page 11 and 12:
How do we use this DNA information?
Page 13 and 14:
What is a SNP? • 99.9% of human D
Page 15 and 16:
SNP effect on performance SNP Var M
Page 17 and 18:
Indentifying Mendelian sampling ter
Page 19 and 20:
Cost of sequencing has decreased Bu
Page 21 and 22:
Sire …..TCACCGCTGAG….. …..CAG
Page 23 and 24:
Page 25 and 26:
Page 27 and 28:
Parentage Sire 1 Sire 2 Sire 3 Sire
Page 29 and 30:
Recessive genetic disorders AB AB A
Page 31 and 32:
To Conclude • Differences seen be
Page 33 and 34:
Genomic Advances in Parentage Verif
Page 35 and 36:
U.S. Department of Agriculture, Agr
Page 37 and 38:
Blood Typing >1990’s Used to dete
Page 39 and 40:
Used to detect bi-allelic polymorph
Page 41 and 42:
Technology Transfer via Imputation
Page 43 and 44:
Impute ISAG cattle MS alleles from
Page 45 and 46:
SNP haplotype to MS allele BM1824 I
Page 47 and 48:
Validate Cattle with SNP and MS on
Page 49 and 50:
Validate Phase, impute, check 316 S
Page 51 and 52:
Validate Phase, impute, check 316 S
Page 53 and 54:
Validation with DAIRY table Order:
Page 55 and 56:
Microsatellite Imputation 2 nd Stud
Page 57 and 58:
Initial Results 642 456 312 233 220
Page 59 and 60:
Acknowledgements • BFGL (USDA-ARS
Page 61 and 62:
Parentage verification Genomic sele
Page 63 and 64:
LD+ content (V1-19K) • Genomic se
Page 65 and 66:
Proportion allele concordance 1.00
Page 67 and 68:
• CVM • BLAD Lethal Recessives
Page 69 and 70: Major genes • 14 major genes incl
Page 71 and 72: From just 1 hair sample! Calf ID CV
Page 73 and 74: Conclusions • Custom chip - value
Page 75 and 76: Implementation of Genomic Services
Page 77 and 78: What is Genotyping? • Identifying
Page 79 and 80: Typical example of processing a Bov
Page 81 and 82: ICBF & Teagasc Genomics Conference
Page 93 and 94: Work Flow Summary • Sample assign
Page 95 and 96: IRISH CATTLE BREEDING FEDERATION Ge
Page 97 and 98: © Irish Cattle Breeding Federation
Page 99 and 100: User friendly, fully integrated, tr
Page 101 and 102: AI Company/Breed Society Order Scre
Page 103 and 104: HerdPlus® User genotype request sc
Page 111 and 112: VIEW YOUR RESULTS Genomic Evaluatio
Page 115 and 116: Chip Type Number of animals genotyp
Page 117 and 118: LIST OF BEEF BULLS WANTED Contact I
Page 119: © Irish Cattle Breeding Federation
Page 123 and 124: Pedigree dairy registrations (2011)
Page 125 and 126: Moving Beef to SNP’s for parentag
Page 127 and 128: Moving beef industry to SNP’s for
Page 129 and 130: Quantifying the Benefits. A quick s
show all

Genomics – A New Era for Cattle Breeding. Session - ICBF

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?