Genomics – A New Era for Cattle Breeding. Session - ICBF

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© Irish Cattle Breeding Federation Soc. Ltd 2012 BEEF BULLS WANTED Large reference population needed for each breed to estimate the genetic marker (SNP) effects. 116
LIST OF BEEF BULLS WANTED Contact ICBF on 1850 600 900 if you have any of these straws © Irish Cattle Breeding Federation Soc. Ltd 2012 ANALYSIS OF MAIN BEEF BREEDS IN MASTERFILE ABOVE BREED HD GENOTYPES HAVE DNA WANT AA 364 63 268 CH 866 192 403 HE 284 44 426 LM 951 163 203 SI 343 40 176 117
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Genomics - A New Era for Cattle Bre
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Session 1. Genomics & parentage ide
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Introduction to Animal Breeding & G
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Traditional Animal Breeding • Cal
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Using technology of today • At bi
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How do we use this DNA information?
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What is a SNP? • 99.9% of human D
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SNP effect on performance SNP Var M
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Indentifying Mendelian sampling ter
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Cost of sequencing has decreased Bu
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Sire …..TCACCGCTGAG….. …..CAG
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Parentage Sire 1 Sire 2 Sire 3 Sire
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Recessive genetic disorders AB AB A
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To Conclude • Differences seen be
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Genomic Advances in Parentage Verif
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U.S. Department of Agriculture, Agr
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Blood Typing >1990’s Used to dete
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Used to detect bi-allelic polymorph
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Technology Transfer via Imputation
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Impute ISAG cattle MS alleles from
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SNP haplotype to MS allele BM1824 I
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Validate Cattle with SNP and MS on
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Validate Phase, impute, check 316 S
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Validate Phase, impute, check 316 S
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Validation with DAIRY table Order:
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Microsatellite Imputation 2 nd Stud
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Initial Results 642 456 312 233 220
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Acknowledgements • BFGL (USDA-ARS
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Parentage verification Genomic sele
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LD+ content (V1-19K) • Genomic se
Page 65 and 66: Proportion allele concordance 1.00
Page 67 and 68: • CVM • BLAD Lethal Recessives
Page 69 and 70: Major genes • 14 major genes incl
Page 71 and 72: From just 1 hair sample! Calf ID CV
Page 73 and 74: Conclusions • Custom chip - value
Page 75 and 76: Implementation of Genomic Services
Page 77 and 78: What is Genotyping? • Identifying
Page 79 and 80: Typical example of processing a Bov
Page 81 and 82: ICBF & Teagasc Genomics Conference
Page 93 and 94: Work Flow Summary • Sample assign
Page 95 and 96: IRISH CATTLE BREEDING FEDERATION Ge
Page 97 and 98: © Irish Cattle Breeding Federation
Page 99 and 100: User friendly, fully integrated, tr
Page 101 and 102: AI Company/Breed Society Order Scre
Page 103 and 104: HerdPlus® User genotype request sc
Page 111 and 112: VIEW YOUR RESULTS Genomic Evaluatio
Page 115: Chip Type Number of animals genotyp
Page 121 and 122: Genomics & Breeding Programs • Ge
Page 123 and 124: Pedigree dairy registrations (2011)
Page 125 and 126: Moving Beef to SNP’s for parentag
Page 127 and 128: Moving beef industry to SNP’s for
Page 129 and 130: Quantifying the Benefits. A quick s
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Genomics – A New Era for Cattle Breeding. Session - ICBF

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