Genomics – A New Era for Cattle Breeding. Session - ICBF

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© Irish Cattle Breeding Federation Soc. Ltd 2012 Incorrect Sires Animals that have incorrect sires are identified. Currently 7.5% error rate on sire. These are checked against sires in the database. Reduces error rate down to 1.5%. Changes are made and farmers and Breed Societies notified. Unassigned sires are likely to be un genotyped stock bulls. % WRONG SIRE % SIRE ASSIGNED MALES 7 76 24 FEMALES 8 73 27 114 % SIRE REMOVED
Chip Type Number of animals genotyped AI Companies 2011 © Irish Cattle Breeding Federation Soc. Ltd 2012 AI Companies 2012 Farmers 2011 115 Farmers 2012 Others 2011 Others 2012 Totals 3k 1,768 35 351 10 297 0 2,461 7k-LD 6 3,301 0 6,587 20 496 10,410 54k 117 240 46 2 54 27 486 800K- HD 0 0 0 0 1,999 781 2,780 Totals 1,891 3,576 397 6,599 2,370 1,304 Overall animals genotyped =16,137
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Genomics - A New Era for Cattle Bre
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Session 1. Genomics & parentage ide
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Introduction to Animal Breeding & G
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Traditional Animal Breeding • Cal
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Using technology of today • At bi
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How do we use this DNA information?
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What is a SNP? • 99.9% of human D
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SNP effect on performance SNP Var M
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Indentifying Mendelian sampling ter
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Cost of sequencing has decreased Bu
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Sire …..TCACCGCTGAG….. …..CAG
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Parentage Sire 1 Sire 2 Sire 3 Sire
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Recessive genetic disorders AB AB A
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To Conclude • Differences seen be
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Genomic Advances in Parentage Verif
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U.S. Department of Agriculture, Agr
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Blood Typing >1990’s Used to dete
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Used to detect bi-allelic polymorph
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Technology Transfer via Imputation
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Impute ISAG cattle MS alleles from
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SNP haplotype to MS allele BM1824 I
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Validate Cattle with SNP and MS on
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Validate Phase, impute, check 316 S
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Validate Phase, impute, check 316 S
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Validation with DAIRY table Order:
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Microsatellite Imputation 2 nd Stud
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Initial Results 642 456 312 233 220
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Acknowledgements • BFGL (USDA-ARS
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Parentage verification Genomic sele
Page 63 and 64: LD+ content (V1-19K) • Genomic se
Page 65 and 66: Proportion allele concordance 1.00
Page 67 and 68: • CVM • BLAD Lethal Recessives
Page 69 and 70: Major genes • 14 major genes incl
Page 71 and 72: From just 1 hair sample! Calf ID CV
Page 73 and 74: Conclusions • Custom chip - value
Page 75 and 76: Implementation of Genomic Services
Page 77 and 78: What is Genotyping? • Identifying
Page 79 and 80: Typical example of processing a Bov
Page 81 and 82: ICBF & Teagasc Genomics Conference
Page 93 and 94: Work Flow Summary • Sample assign
Page 95 and 96: IRISH CATTLE BREEDING FEDERATION Ge
Page 97 and 98: © Irish Cattle Breeding Federation
Page 99 and 100: User friendly, fully integrated, tr
Page 101 and 102: AI Company/Breed Society Order Scre
Page 103 and 104: HerdPlus® User genotype request sc
Page 111 and 112: VIEW YOUR RESULTS Genomic Evaluatio
Page 113: © Irish Cattle Breeding Federation
Page 117 and 118: LIST OF BEEF BULLS WANTED Contact I
Page 121 and 122: Genomics & Breeding Programs • Ge
Page 123 and 124: Pedigree dairy registrations (2011)
Page 125 and 126: Moving Beef to SNP’s for parentag
Page 127 and 128: Moving beef industry to SNP’s for
Page 129 and 130: Quantifying the Benefits. A quick s
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Genomics – A New Era for Cattle Breeding. Session - ICBF

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