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Genomics - A New Era for Cattle Bre
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Session 1. Genomics & parentage ide
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Introduction to Animal Breeding & G
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Traditional Animal Breeding • Cal
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Using technology of today • At bi
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How do we use this DNA information?
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What is a SNP? • 99.9% of human D
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SNP effect on performance SNP Var M
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Indentifying Mendelian sampling ter
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Cost of sequencing has decreased Bu
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Sire …..TCACCGCTGAG….. …..CAG
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Sire …..TCACCGCTGAG….. …..CAG
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Sire …..TCACCGCTGAG….. …..CAG
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Parentage Sire 1 Sire 2 Sire 3 Sire
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Recessive genetic disorders AB AB A
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To Conclude • Differences seen be
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Genomic Advances in Parentage Verif
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U.S. Department of Agriculture, Agr
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Blood Typing >1990’s Used to dete
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Used to detect bi-allelic polymorph
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Technology Transfer via Imputation
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Impute ISAG cattle MS alleles from
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SNP haplotype to MS allele BM1824 I
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Validate Cattle with SNP and MS on
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Validate Phase, impute, check 316 S
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Validate Phase, impute, check 316 S
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Validation with DAIRY table Order:
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Microsatellite Imputation 2 nd Stud
- Page 57 and 58: Initial Results 642 456 312 233 220
- Page 59 and 60: Acknowledgements • BFGL (USDA-ARS
- Page 61 and 62: Parentage verification Genomic sele
- Page 63 and 64: LD+ content (V1-19K) • Genomic se
- Page 65 and 66: Proportion allele concordance 1.00
- Page 67 and 68: • CVM • BLAD Lethal Recessives
- Page 69 and 70: Major genes • 14 major genes incl
- Page 71 and 72: From just 1 hair sample! Calf ID CV
- Page 73 and 74: Conclusions • Custom chip - value
- Page 75 and 76: Implementation of Genomic Services
- Page 77 and 78: What is Genotyping? • Identifying
- Page 79 and 80: Typical example of processing a Bov
- Page 81 and 82: ICBF & Teagasc Genomics Conference
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- Page 93 and 94: Work Flow Summary • Sample assign
- Page 95 and 96: IRISH CATTLE BREEDING FEDERATION Ge
- Page 97 and 98: © Irish Cattle Breeding Federation
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- Page 111 and 112: VIEW YOUR RESULTS Genomic Evaluatio
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- Page 115 and 116: Chip Type Number of animals genotyp
- Page 117 and 118: LIST OF BEEF BULLS WANTED Contact I
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- Page 121 and 122: Genomics & Breeding Programs • Ge
- Page 123 and 124: Pedigree dairy registrations (2011)
- Page 125 and 126: Moving Beef to SNP’s for parentag
- Page 127 and 128: Moving beef industry to SNP’s for
- Page 129 and 130: Quantifying the Benefits. A quick s