Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Beyond IUI, IVF and ICSI - New developments in - eshre 2013
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Table 1. Results of oocyte electroactivation <strong>in</strong> 10 <strong>ICSI</strong> cycles for patients<br />
with previous total failure of fertilization<br />
Case<br />
number<br />
1<br />
2<br />
3<br />
4<br />
5<br />
6<br />
7<br />
8<br />
9<br />
10<br />
Total<br />
Oocytes<br />
Retrieved<br />
13<br />
4<br />
18<br />
12<br />
14<br />
12<br />
4<br />
12<br />
6<br />
8<br />
103<br />
MII<br />
oocytes<br />
8<br />
4<br />
10<br />
7<br />
8<br />
6<br />
4<br />
9<br />
5<br />
5<br />
66<br />
2 PN<br />
oocytes<br />
5<br />
1<br />
2<br />
3<br />
3<br />
2<br />
2<br />
7<br />
2<br />
5<br />
31<br />
Embryos NO.<br />
of<br />
transferred<br />
3<br />
1<br />
2<br />
3<br />
2<br />
1<br />
2<br />
3<br />
2<br />
3<br />
22<br />
NO. of embryos<br />
Cryopreserved<br />
--<br />
--<br />
--<br />
--<br />
--<br />
--<br />
--<br />
4<br />
--<br />
2<br />
6<br />
Pregnancy<br />
results<br />
-ve<br />
-ve<br />
-ve<br />
s<strong>in</strong>gle<br />
-ve<br />
-ve<br />
-ve<br />
s<strong>in</strong>gle<br />
s<strong>in</strong>gle<br />
s<strong>in</strong>gle<br />
4 healthy<br />
babies<br />
Note: -ve = negative Mansour,et al.,2009<br />
Degenerated oocytes<br />
(n=98) 5.9%<br />
assessed for eligibility (n=249)<br />
selected for t he study (n=246)<br />
started ovarian stimulation (n = 244)<br />
underwent ovum pick-up (n=241)<br />
retrieved oocytes (n=3516)<br />
MII oocytes (n=3075)<br />
excluded (n=3)<br />
not meet<strong>in</strong>g <strong>in</strong>clusion criteria<br />
refused to participate<br />
(n=2)<br />
dropped due to poor ovarian<br />
response (n=3)<br />
G.V oocytes (n=290)<br />
MI oocytes (n=151)<br />
electroactivated oocytes (n=1640) control oocytes (n=1435)<br />
Fertilized oocytes<br />
(n=1116) 68%<br />
Degenerated oocytes<br />
(n=70) 4.9%<br />
Fertilized oocytes<br />
(n= 872)60%<br />
Mansour,et al.,2009<br />
Table 2. The effect of electroactivation on the fertilization <strong>and</strong> rates of sibl<strong>in</strong>g<br />
oocytes of 241 <strong>ICSI</strong> cycles with expected poor or failure of fertilization.<br />
Parameter<br />
Electroactivated<br />
oocytes<br />
Control<br />
oocytes<br />
No. (mean ± SD) of metaphase II oocytes 1,640 (6.8 ± 2.48) 1,435 (5.95 ± 29)<br />
No. (mean ± SD) of 2-pronuclear oocytes 1,116 (4.63 ± 2.3) 872 (3.62 ± 1.96)<br />
Fertilization rate (%) 68<br />
60<br />
a Fertilization rate (%)<br />
68<br />
60<br />
No. (mean ± SD) of Degenerated oocytes 98 ( 1.73 ± 1.2) 70 (1.39 ± 0.79)<br />
Degeneration rate (%) 5.9<br />
4.9%<br />
b<br />
a Odds ratio = 1.397, 95% confidence <strong>in</strong>terval = 1.198 to 1.63, P< .001.<br />
b Odds ratio = 0.96 , 95% confidence <strong>in</strong>terval = 0.73 to 1.26, P=0.821<br />
Mansour,et al.,2009<br />
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