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Beyond IUI, IVF and ICSI - New developments in - eshre 2013

Beyond IUI, IVF and ICSI - New developments in - eshre 2013

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Unexpected Azoospermia at OPU<br />

Will appear more often <strong>in</strong> :<br />

1. crypto azoospermia cases<br />

2. Reversal of vasectomy<br />

Meniru et. Al, 1997<br />

Unexpected Aspermia at OPU<br />

May appear unrelated to sperm characteristics<br />

The occurrence of unexpected aspermia<br />

Rare event. Less than 0.5%<br />

Assaf Harofeh, TAU<br />

The occurrence of unexpected azoopermia<br />

Rare event. About 0.5%<br />

Assaf Harofeh, TAU<br />

Number of treated cycles <strong>in</strong> Assaf Harofeh, TAU is 1100-1200 per year<br />

Approaches to overcome the problem<br />

In cases of aspermia<br />

1. Repeated sperm emission at the cl<strong>in</strong>ic<br />

2. Repeated sperm emission outside the cl<strong>in</strong>ic (home, hotel)<br />

33. Repeated sperm emission by coitus – us<strong>in</strong>g a medical condom<br />

a condom without spermicidal agents<br />

4. Use of Sildenafil (Viagra) <strong>in</strong> case of erectile dysfunction<br />

Time frame:<br />

1-9 hours post OPU time.<br />

This is the <strong>in</strong>terval period for <strong>in</strong>sem<strong>in</strong>ation without compromis<strong>in</strong>g the<br />

oocyte quality, e.g. fertilization rate <strong>and</strong> embryo quality are unchanged<br />

Fisch et al, 1989<br />

Page 78 of 127

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