Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Beyond IUI, IVF and ICSI - New developments in - eshre 2013
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<strong>ICSI</strong> <strong>and</strong> absolute asthenozoospermia (AA)<br />
May be reversible V<strong>and</strong>ervorst et al. 1997<br />
11 couples, 11 first cycles with AA 12.4% FR<br />
9 couples couples, 16 subsequent cycles<br />
0% PR<br />
• 12 cycles with motile sperm 56.5% FR<br />
4 pregnancies<br />
• 4 cycles with immotile sperm 15.6% FR<br />
0 pregnancies<br />
Absolute asthenozoospermia<br />
If no corrective action<br />
If only immotile sperm available<br />
The lab must solve the problem<br />
Challenge = discrim<strong>in</strong>ate immotile live sperm<br />
from immotile dead sperm<br />
Absolute asthenozoospermia<br />
100% immotility <strong>in</strong> the ejaculate<br />
Two possibilities<br />
Viability = 0% necrozoospermia<br />
Viability > 0%<br />
• How to select viable sperm for <strong>ICSI</strong>?<br />
• Exposure to dyes<br />
<br />
Unsuitable for <strong>ICSI</strong><br />
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