Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Beyond IUI, IVF and ICSI - New developments in - eshre 2013
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Ultrastructural defects<br />
Transmission electron microscopy<br />
Ortega et al. 2011 Ortega et al. 2011<br />
Absence of dyne<strong>in</strong> arms Absence of central microtubuli<br />
Necrozoospermia<br />
Rare condition (0.2-0.5% of <strong>in</strong>fertile men)<br />
Orig<strong>in</strong> <strong>in</strong> testis or epididymis<br />
Accurate cl<strong>in</strong>ical assessment<br />
( 9+0 )<br />
medical history, urogenital exam<strong>in</strong>ation, hormone profile, semen <strong>and</strong><br />
ur<strong>in</strong>e culture, sem<strong>in</strong>al biochemistry, transrectal ultrosonography,<br />
testicular biopsy p y<br />
Lecomte et al. 1998, Tournaye et al., 1998<br />
Identify the orig<strong>in</strong> <strong>and</strong> correct if possible<br />
Not always permanent condition<br />
Role of testis biopsy<br />
Tournaye et al. 1996<br />
<strong>ICSI</strong> <strong>and</strong> absolute asthenozoospermia<br />
<strong>ICSI</strong> = only possible treatment option<br />
High rate of fertilization failure (Liu et al. 1995)<br />
Decreased fertilization <strong>and</strong> pregnancy rates (Nagy et al. 1995)<br />
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