Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Beyond IUI, IVF and ICSI - New developments in - eshre 2013
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
No relationship between chromosome aberrations<br />
<strong>and</strong> vacuole-like structures on human sperm head<br />
No relationship between chromosome aberrations<br />
<strong>and</strong> vacuole-like structures on human sperm head<br />
Corrective role of the oocyte<br />
An <strong>in</strong>tact DNA does not appear to be a prerequisite for a successful fertilization as<br />
proven by the ability of <strong>ICSI</strong>, to yield satisfactory fertilization <strong>and</strong> pregnancy<br />
outcomes with compromised semen parameters, or immature spermatozoa such<br />
as those retrieved from the epididymis or result<strong>in</strong>g from a compromised<br />
spermatogenesis such as testicular specimens of non‐obstructive azoospermic<br />
men.<br />
These f<strong>in</strong>d<strong>in</strong>gs highlight the role of the oocyte as<br />
more than just a source of maternal DNA <strong>and</strong><br />
nutrients to the presumptive conceptus, but also<br />
a contribut<strong>in</strong>g <strong>in</strong>tricate mach<strong>in</strong>ery that can undo<br />
the damag<strong>in</strong>g effects of a faulty male genome.<br />
Page 43 of 127
Change language