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Beyond IUI, IVF and ICSI - New developments in - eshre 2013

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CD45 + Dynabeads <strong>and</strong> Leukocyte removal from Sperm prep ns<br />

tes (104 Leucocy / ml)<br />

6<br />

5<br />

4<br />

3<br />

2<br />

1<br />

0<br />

Semen<br />

Leucocytes<br />

**<br />

Pre- Post-<br />

Dynabead<br />

nce 106 Chemilum<strong>in</strong>escen counts/5 m<strong>in</strong>)<br />

20<br />

10<br />

0<br />

Chemilum<strong>in</strong>escence<br />

*<br />

Pre- Post-<br />

Dynabead<br />

Oocyte Penetration<br />

(sperm/egg)<br />

2.0<br />

1.0<br />

0.0<br />

Oocyte Penetration<br />

**<br />

Pre- Post-<br />

Dynabead<br />

Problems associated with Assisted Conception<br />

Incidence of stillbirth 4 times higher follow<strong>in</strong>g <strong>IVF</strong>/<strong>ICSI</strong> than babies conceived<br />

naturally (Wisborg et al., 2010)<br />

Children conceived with ART also have about twice the risk of hav<strong>in</strong>g a<br />

major birth defect or low birth weight than children conceived naturally<br />

(Hansen et al., 2002)<br />

Cumulative Prevalencce<br />

of<br />

Major Birth Defects (%)<br />

10<br />

8<br />

6<br />

4<br />

2<br />

<strong>ICSI</strong><br />

<strong>IVF</strong><br />

Natural conception<br />

0<br />

Prenatal

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