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Plants with toxic alkaloids - University of Washington

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<strong>Plants</strong> <strong>with</strong> <strong>toxic</strong> amino acids and proteins<br />

Lectins are sugar-binding proteins<br />

that are highly specific for their<br />

sugar moieties. They moderate<br />

biological recognition like viruses<br />

use lectins to attach themselves to<br />

the cells.<br />

Plant lectins like arbrin and ricin<br />

attach themselves to the<br />

glycoproteins at the surface <strong>of</strong><br />

erythrocytes and cause them to<br />

clump together hemagglutinins<br />

Peter Hermann Stillmark in 1888 (<strong>University</strong> <strong>of</strong> Dorpat) isolated ricin, an extremely <strong>toxic</strong><br />

hemagglutinin, from seeds <strong>of</strong> the castor plant (Ricinus communis) The first lectin to be<br />

purified on a large scale and available on a commercial basis was concanavalin A from<br />

the jack bean.

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